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Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2013, Volume 56, Issue 24, pp. 9820 - 9825
Diacylglycerol O-acyltransferase 1 (DGAT1) has recently become a highly interesting target for metabolic disorders as well as for hepatitis C virus (HCV).... 
Animals | Enzyme Inhibitors - chemistry | Humans | Enzyme Inhibitors - pharmacology | Molecular Structure | Structure-Activity Relationship | Diacylglycerol O-Acyltransferase - metabolism | Enzyme Inhibitors - chemical synthesis | Diacylglycerol O-Acyltransferase - antagonists & inhibitors | Drug Discovery
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0125921
Retinyl esters represent an insoluble storage form of vitamin A and are substrates for the retinoid isomerase (Rpe65) in cells of the retinal pigment... 
STORAGE | VISUAL CYCLE | 11-CIS-RETINOL | TRIACYLGLYCEROL SYNTHESIS | MULTIDISCIPLINARY SCIENCES | ISOMERASE | BINDING-PROTEIN | VITAMIN-A | MULLER CELLS | RPE65 | LECITHIN | Retinal Pigment Epithelium - metabolism | Retina - metabolism | Mice, Inbred C57BL | Cells, Cultured | Palmitoyl Coenzyme A - metabolism | Esters - metabolism | Acyltransferases - metabolism | Retinaldehyde - metabolism | Vitamin A - metabolism | Animals | Diacylglycerol O-Acyltransferase - genetics | Retina - cytology | Retina - ultrastructure | Retinal Pigment Epithelium - ultrastructure | Gene Deletion | cis-trans-Isomerases - metabolism | Mice, Inbred BALB C | Diacylglycerol O-Acyltransferase - metabolism | Retinal Pigment Epithelium - cytology | Diacylglycerol O-Acyltransferase - analysis | Vitamin A | Complications and side effects | Care and treatment | Transferases | Influence | Research | Health aspects | Retinal diseases | Neurosciences | Lecithin | Photopigments | Diacylglycerol | Visual pigments | Retina | Esters | Biochemistry | Biology | Glial cells | Isomers | Retinal pigment epithelium | Proteins | Diacylglycerol O-acyltransferase | Ultrastructure | Pigments | Coenzyme A | Catalysis | Chemical synthesis | Research & development--R&D | Epithelium | Substrates | Photoreceptors | Mice | Enzyme kinetics | Laboratory animals | Research & development | R&D
Journal Article
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, p. 14610
Lipids are the primary components of the skin permeability barrier, which is the body's most powerful defensive mechanism against pathogens. Acylceramide... 
Biocatalysis | Linoleic Acid - metabolism | Skin - metabolism | Humans | Substrate Specificity | Lipase - metabolism | Ceramides - biosynthesis | Triglycerides - metabolism | HEK293 Cells | Sjogren-Larsson Syndrome - metabolism | Diacylglycerol O-Acyltransferase - metabolism | Sjogren-Larsson Syndrome - pathology | Acylation
Journal Article
Journal Article
Plant Biotechnology Journal, ISSN 1467-7644, 02/2014, Volume 12, Issue 2, pp. 231 - 239
Journal Article