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Journal of Clinical Oncology, ISSN 0732-183X, 07/2012, Volume 30, Issue 21, pp. 2691 - 2697
Monoclonal antibodies directed against the immune checkpoint protein cytotoxic T-lymphocyte antigen-4 (CTLA-4; CD152)-ipilimumab and tremelimumab-have been... 
REGRESSION | METASTATIC MELANOMA | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | EFFICACY | ONCOLOGY | PHASE-II | MONOCLONAL-ANTIBODY | CTLA-4 | PATIENT | CANCER-IMMUNOTHERAPY | BLOCKADE | Stevens-Johnson Syndrome - immunology | Peripheral Nervous System Diseases - chemically induced | Skin Neoplasms - drug therapy | Humans | Ipilimumab | Antibodies, Monoclonal - adverse effects | Scleritis - chemically induced | Antineoplastic Agents - administration & dosage | Liver - immunology | Liver - drug effects | Antineoplastic Agents - adverse effects | Diarrhea - immunology | Pancreatitis - immunology | Scleritis - immunology | Mucous Membrane - drug effects | Colitis - immunology | Peripheral Nervous System Diseases - immunology | Antibodies, Monoclonal - immunology | Drug Eruptions - immunology | Skin - immunology | Melanoma - metabolism | Skin Neoplasms - pathology | Skin Neoplasms - immunology | Antineoplastic Agents - immunology | CTLA-4 Antigen - drug effects | Lymphatic Diseases - immunology | Antibodies, Monoclonal - pharmacokinetics | CTLA-4 Antigen - immunology | Pancreatitis - chemically induced | Melanoma - secondary | Chemical and Drug Induced Liver Injury - immunology | Pituitary Gland - immunology | Skin Neoplasms - metabolism | Lymphatic Diseases - chemically induced | Mucous Membrane - immunology | Antibodies, Monoclonal - administration & dosage | Melanoma - immunology | Uveitis - immunology | Melanoma - drug therapy | Uveitis - chemically induced | Pituitary Gland - drug effects | Skin - drug effects | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 20, pp. 2457 - 2464
Highlights • We developed and tested a new oral ETEC vaccine in mice, alone and with an adjuvant. • The vaccine contains E. coli overexpressing CFA/I, CS3, CS5... 
Allergy and Immunology | Vaccine | Mucosal immunity | Immune responses | ETEC | dmLT | Colonization factors | DmLT | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | DIARRHEA | PREVENTION | IMMUNOLOGY | VIBRIO-CHOLERAE | CELL CHOLERA VACCINE | TRAVELERS | CONSTRUCTION | ENTEROTOXIGENIC ESCHERICHIA-COLI | INTRANASAL IMMUNIZATION | ANTIBODY-RESPONSES | Immunity, Mucosal - immunology | Adjuvants, Immunologic - administration & dosage | Immunoglobulin G - blood | Escherichia coli Infections - prevention & control | Antigens, Bacterial - immunology | Antigens, Bacterial - genetics | Intestines - immunology | Enterotoxins - immunology | Escherichia coli Proteins - administration & dosage | Immunoglobulin G - immunology | Cholera Toxin - immunology | Bacterial Toxins - genetics | Female | Escherichia coli Proteins - immunology | Immunoglobulin G - analysis | Mutant Proteins - immunology | Fimbriae Proteins - immunology | Cholera Toxin - administration & dosage | Antibody Formation - immunology | Vaccines, Inactivated - genetics | Administration, Oral | Bacterial Toxins - immunology | Escherichia coli Infections - microbiology | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Mutant Proteins - administration & dosage | Enterotoxins - administration & dosage | Vaccines, Inactivated - adverse effects | Enterotoxins - genetics | Vaccines, Inactivated - immunology | Animals | Escherichia coli Vaccines - adverse effects | Fimbriae Proteins - genetics | Vaccines, Inactivated - administration & dosage | Cholera Toxin - genetics | Immunoglobulin A - immunology | Escherichia coli Proteins - genetics | Immunoglobulin A - blood | Bacterial Toxins - administration & dosage | Escherichia coli Infections - immunology | Escherichia coli Vaccines - genetics | Mice | Mice, Inbred BALB C | Escherichia coli Vaccines - immunology | Immunoglobulin A - analysis | Antigens | Safety and security measures | Analysis | Escherichia coli | Bacteria | Vaccines | Contamination | Proteins | Studies | Immunology | E coli | Rodents | Index Medicus | Basic Medicine | Medicinska grundvetenskaper
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 163, pp. 60 - 65
Abstract Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a monogenic autoimmune disease characterized by early-onset... 
Allergy and Immunology | Autoimmunity | IPEX | Mutation | FOXP3 | Primary immunodeficiency | X-LINKED SYNDROME | ENTEROPATHY | STABILITY | IMMUNOLOGY | IMMUNE DYSREGULATION | DIMER | SEQUENCE | DISEASE | REGULATORY T-CELLS | POLYENDOCRINOPATHY | IMMUNODYSREGULATION | Eczema - genetics | Eczema - immunology | Immune System Diseases - genetics | Humans | Diabetes Mellitus, Type 1 - congenital | Infant | Male | Meningoencephalitis - immunology | Thrombocytopenia - genetics | Immunoglobulin E - immunology | Diarrhea - immunology | Eosinophilia - genetics | Fatal Outcome | Hepatomegaly - immunology | Genetic Diseases, X-Linked - genetics | Diabetes Mellitus, Type 1 - immunology | Dimerization | Hemorrhage - genetics | Sepsis - immunology | Splenomegaly - genetics | Growth Disorders - immunology | Hemorrhage - immunology | Splenomegaly - immunology | Thrombocytopenia - immunology | Immune System Diseases - immunology | Leukocytosis - immunology | Meningoencephalitis - genetics | Diabetes Mellitus, Type 1 - genetics | Models, Molecular | Klebsiella Infections - genetics | Hepatomegaly - genetics | Forkhead Transcription Factors - genetics | Sepsis - genetics | Lung Diseases - immunology | Genetic Diseases, X-Linked - immunology | Immune System Diseases - congenital | Thymus Gland - abnormalities | Lung Diseases - genetics | Eosinophilia - immunology | Diarrhea - genetics | Klebsiella Infections - immunology | Phenylalanine - genetics | Hydrophobic and Hydrophilic Interactions | Growth Disorders - genetics | Leukocytosis - genetics
Journal Article
Clinical and Vaccine Immunology, ISSN 1556-6811, 12/2016, Volume 23, Issue 12, pp. 908 - 917
Journal Article
Immunity, ISSN 1074-7613, 02/2015, Volume 42, Issue 2, pp. 279 - 293
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42788
Group A Rotaviruses are the most common cause of severe, dehydrating diarrhea in children worldwide. The aim of the present work was to evaluate protection... 
SECRETING CELL RESPONSES | EGG-YOLK IMMUNOGLOBULIN | WA HUMAN ROTAVIRUS | NEWBORN CALVES | CLINICAL-TRIAL | BOVINE ROTAVIRUS | IMMUNE-RESPONSES | NASAL IMMUNIZATION | MULTIDISCIPLINARY SCIENCES | VIRUS-LIKE PARTICLES | MATERNAL ANTIBODIES | Germ-Free Life - immunology | Immunoglobulins - immunology | Cell Count | Humans | Rotavirus - immunology | Sus scrofa - blood | Diarrhea - prevention & control | Neutralization Tests | Virus Shedding | Diarrhea - blood | Antibody Specificity - immunology | Immunoglobulin G - immunology | Diarrhea - immunology | Capsid Proteins - immunology | Rotavirus Infections - virology | Disease Models, Animal | Animals, Newborn | Duodenum - immunology | Duodenum - virology | Antibody Formation - immunology | Enzyme-Linked Immunosorbent Assay | Administration, Oral | Egg Yolk - immunology | Diarrhea - virology | Rotavirus Infections - blood | Sus scrofa - virology | Rotavirus Infections - immunology | Antigens, Viral - immunology | Animals | Antibody-Producing Cells - immunology | Chickens | Duodenum - pathology | Immunoglobulin A - immunology | Antibodies, Viral - immunology | Sus scrofa - immunology | Rotavirus Infections - prevention & control | Swine | Analysis | Immunoglobulin G | Diarrhea | Infants | Immunoglobulin A | Enzyme-linked immunosorbent assay | Milk | Neonates | Poultry | Antibodies | Viruses | Vaccines | Dehydration | Cow's milk | Intestine | Children | Supplementation | Immune system | Yolk | Immunoglobulins | Immune response | Duodenum | Dietary supplements | Oral administration | Preventive medicine | Hogs | Neutralization
Journal Article
Immunity, ISSN 1074-7613, 10/2015, Volume 43, Issue 4, pp. 788 - 802
Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin-9 (IL-9). However, the primary cellular source of IL-9 and the... 
HETEROGENEITY | PROGENITORS | LUNG | PROTECTIVE IMMUNITY | TRICHINELLA-SPIRALIS | RECEPTOR | INFECTION | DIFFERENTIATION | IMMUNOLOGY | ANAPHYLAXIS | SEVERITY | Ovalbumin - immunology | Species Specificity | Humans | Molecular Sequence Data | Adoptive Transfer | Mastocytosis - immunology | Interleukin-9 - biosynthesis | RNA, Messenger - biosynthesis | Ovalbumin - toxicity | Food Hypersensitivity - immunology | Immunoglobulin E - immunology | Interleukins - physiology | Intestinal Mucosa - immunology | Base Sequence | Diarrhea - immunology | Mast Cells - metabolism | Anaphylaxis - immunology | STAT6 Transcription Factor - physiology | Interleukins - biosynthesis | Food Hypersensitivity - etiology | Interleukin-9 - secretion | Duodenum - immunology | Mast Cells - immunology | Disease Susceptibility | Anaphylaxis - etiology | Bone Marrow Cells - cytology | RNA, Messenger - genetics | Hypersensitivity, Immediate - complications | Mastocytosis - pathology | Chymases - biosynthesis | Mice, Inbred Strains | Chymases - genetics | Food Hypersensitivity - pathology | Cell Lineage | Animals | Ovalbumin - administration & dosage | Interleukin-9 - genetics | Duodenum - pathology | Diarrhea - etiology | T-Lymphocytes - immunology | Mice | Mast Cells - transplantation | Interleukins - secretion | Immunoglobulin E | Food allergy | Crosslinked polymers | Interleukins | T cells | Proteases | Diarrhea | Food allergies | Peanuts | Cytokines | Rodents | Food
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2013, Volume 190, Issue 9, pp. 4742 - 4753
Journal Article