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The Cochrane database of systematic reviews, ISSN 1469-493X, 2015, Volume 4, Issue 5, p. CD003262
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2019, Volume 380, Issue 11, pp. 1022 - 1032
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2006, Volume 55, Issue 6, pp. 1048 - 1065
Melasma is an irregular brown or grayish-brown facial hypermelanosis, often affecting women, especially those living in areas of intense UV radiation. The... 
FACIAL HYPERPIGMENTATION | CUTANEOUS PIGMENTED LESIONS | RETINOIC ACID | TOPICAL CORTICOSTEROIDS | DARKER-SKINNED PATIENTS | REFRACTORY MELASMA | AZELAIC ACID | SELECTIVE PHOTOTHERMOLYSIS | SWITCHED RUBY-LASER | GLYCOLIC ACID PEELS | DERMATOLOGY | Clinical Trials as Topic - statistics & numerical data | Humans | Pregnancy Complications | Chemexfoliation | Laser Coagulation | Dicarboxylic Acids - pharmacology | Melanosis - therapy | Adrenal Cortex Hormones - therapeutic use | Hydroquinones - pharmacology | Dicarboxylic Acids - therapeutic use | Flavonoids - therapeutic use | Sunlight - adverse effects | Dicarboxylic Acids - adverse effects | Melanosis - etiology | Adult | Female | Drug Therapy, Combination | Tretinoin - pharmacology | Randomized Controlled Trials as Topic - statistics & numerical data | Double-Blind Method | Gonadal Steroid Hormones - adverse effects | Adrenal Cortex Hormones - pharmacology | Melanosis - drug therapy | Melanosis - prevention & control | Treatment Outcome | Combined Modality Therapy | Dermabrasion | Ultraviolet Rays - adverse effects | Phototherapy | Pregnancy | Adrenal Cortex Hormones - adverse effects | Hydroquinones - adverse effects | Tretinoin - therapeutic use | Skin - radiation effects | Hydroquinones - therapeutic use | Pyrones - therapeutic use | Tretinoin - adverse effects | Medical colleges | Azelaic acid | Radiation | Clinical trials | Dermatologic agents | Melanosis | Health aspects | Tretinoin
Journal Article
Atherosclerosis, ISSN 0021-9150, 10/2018, Volume 277, pp. 195 - 203
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 676 - 683
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 01/2013, Volume 54, Issue 1, pp. 134 - 151
ETC-1002 (8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid) is a novel investigational drug being developed for the treatment of dyslipidemia and other... 
Fatty acid oxidation | LDL-cholesterol | Cardiovascular disease | Cholesterol synthesis | Metabolic syndrome | Fatty acid synthesis | RAT-LIVER | cardiovascular disease | cholesterol synthesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACETYL-COA CARBOXYLASE | RECEPTOR-ALPHA | metabolic syndrome | fatty acid synthesis | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | DENSITY-LIPOPROTEIN | fatty acid oxidation | HEXADECANEDIOIC ACID | PEROXISOME PROLIFERATORS | HEPATOCYTE NUCLEAR FACTOR-4-ALPHA | ALPHA,OMEGA-DICARBOXYLIC ACIDS | Carbohydrate Metabolism - drug effects | AMP-Activated Protein Kinases - metabolism | ATP Citrate (pro-S)-Lyase - antagonists & inhibitors | Liver - enzymology | Fatty Acids - therapeutic use | Obesity - drug therapy | Calcium - metabolism | Diet - adverse effects | Humans | Male | Glucose - biosynthesis | Dicarboxylic Acids - pharmacology | Sterols - biosynthesis | Obesity - blood | Dicarboxylic Acids - therapeutic use | Dyslipidemias - blood | Liver - drug effects | Enzyme Inhibitors - chemistry | Female | Obesity - etiology | ATP Citrate (pro-S)-Lyase - metabolism | Molecular Targeted Therapy - methods | Protein-Serine-Threonine Kinases - metabolism | Biomarkers - metabolism | Cricetinae | Dyslipidemias - drug therapy | Fatty Acids - chemistry | Liver - metabolism | Enzyme Inhibitors - pharmacology | Rats | Biomarkers - blood | Enzyme Activation - drug effects | Enzyme Inhibitors - therapeutic use | Hep G2 Cells | Obesity - metabolism | Dicarboxylic Acids - chemistry | Animals | Signal Transduction - drug effects | Lipid Metabolism - drug effects | Dyslipidemias - metabolism | Glucagon - metabolism | Liver - cytology | Mice | Energy Metabolism - drug effects | Fatty Acids - biosynthesis | Fatty Acids - pharmacology
Journal Article
Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, 02/2011, Volume 25, Issue 2, pp. 188 - 200
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2019, Volume 380, Issue 11, pp. 1033 - 1042
The effects on lipid profiles of pharmacologic inhibition of ATP citrate lyase, an enzyme in the cholesterol–biosynthesis pathway upstream of HMGCR (the target... 
MEDICINE, GENERAL & INTERNAL | METAANALYSIS | INHIBITION | EFFICACY | SAFETY | RISK | PCSK9 | DENSITY-LIPOPROTEIN-CHOLESTEROL | CORONARY-HEART-DISEASE | CITRATE LYASE | GENOME-WIDE ASSOCIATION | ATP Citrate (pro-S)-Lyase - antagonists & inhibitors | Fatty Acids - therapeutic use | Diabetes Mellitus - genetics | Humans | Middle Aged | Male | Risk | Dicarboxylic Acids - pharmacology | Cardiovascular Diseases - genetics | Hypercholesterolemia - drug therapy | Dicarboxylic Acids - therapeutic use | Neoplasms - genetics | Mendelian Randomization Analysis | Cholesterol, LDL - blood | Female | Odds Ratio | Genetic Predisposition to Disease | Membrane Proteins - genetics | ATP Citrate (pro-S)-Lyase - genetics | Lipoproteins - blood | Hypolipidemic Agents - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Hypolipidemic Agents - therapeutic use | Hydroxymethylglutaryl CoA Reductases - genetics | Fatty Acids - pharmacology | Care and treatment | Control | Cholesterol, LDL | Genetic aspects | Cardiovascular diseases | Health aspects | Risk factors | Citric acid | Plasma | Lipoproteins (low density) | Medical research | Biomedical research | Heart attacks | Lipids | Cardiovascular disease | Grants | Low density lipoprotein | Cholesterol | Studies | Genetic variance | Acids | Councils | Coronary vessels | Biomarkers | Coenzyme A | Diabetes | Drug therapy | Health risk assessment | Statins | Cancer | Reductase
Journal Article