X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6374) 6374
Publication (325) 325
Newsletter (102) 102
Book Review (67) 67
Magazine Article (41) 41
Paper (6) 6
Trade Publication Article (6) 6
Book Chapter (5) 5
Conference Proceeding (5) 5
Dissertation (5) 5
Data Set (4) 4
Web Resource (4) 4
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
pharmacology & pharmacy (2905) 2905
diclofenac (2844) 2844
animals (2238) 2238
humans (2030) 2030
male (2004) 2004
index medicus (1809) 1809
diclofenac - pharmacology (1514) 1514
rats (1250) 1250
female (1193) 1193
diclofenac sodium (1007) 1007
diclofenac - administration & dosage (942) 942
anti-inflammatory agents, non-steroidal - pharmacology (831) 831
adult (721) 721
anti-inflammatory agents, non-steroidal - administration & dosage (674) 674
nonsteroidal antiinflammatory drugs (646) 646
nonsteroidal anti-inflammatory drugs (640) 640
diclofenac - pharmacokinetics (616) 616
diclofenac - chemistry (612) 612
chemistry, medicinal (555) 555
middle aged (551) 551
diclofenac - therapeutic use (544) 544
mice (526) 526
rats, wistar (524) 524
drugs (520) 520
analysis (472) 472
anti-inflammatory agents, non-steroidal - therapeutic use (455) 455
solubility (451) 451
dose-response relationship, drug (438) 438
inflammation (406) 406
pharmacokinetics (399) 399
diclofenac - adverse effects (398) 398
anti-inflammatory agents, non-steroidal - pharmacokinetics (397) 397
pharmacology/toxicology (395) 395
anti-inflammatory agents, non-steroidal - adverse effects (388) 388
in-vitro (384) 384
pain (355) 355
toxicology (354) 354
aged (351) 351
sodium (351) 351
diclofenac - analogs & derivatives (348) 348
anti-inflammatory agents, non-steroidal - chemistry (344) 344
time factors (312) 312
indomethacin (311) 311
chemistry, multidisciplinary (309) 309
kinetics (308) 308
in vitro techniques (306) 306
rats, sprague-dawley (306) 306
diclofenac - metabolism (305) 305
drug delivery systems (299) 299
research (289) 289
ibuprofen (287) 287
cyclooxygenase inhibitors - pharmacology (283) 283
inhibition (282) 282
double-blind method (280) 280
chemistry, pharmaceutical (273) 273
administration, oral (269) 269
pharmacology (265) 265
osteoarthritis (263) 263
drug interactions (255) 255
analgesics (251) 251
tablets (246) 246
hydrogen-ion concentration (241) 241
administration, cutaneous (240) 240
permeability (234) 234
pharmacy (231) 231
rabbits (231) 231
medicine & public health (229) 229
release (229) 229
particle size (227) 227
biochemistry & molecular biology (224) 224
nsaids (224) 224
delayed-action preparations (220) 220
rheumatoid-arthritis (213) 213
celecoxib (212) 212
biomedicine (210) 210
skin (209) 209
indomethacin - pharmacology (206) 206
metabolism (206) 206
formulation (204) 204
bioavailability (203) 203
rat (201) 201
disease models, animal (198) 198
carrageenan (197) 197
chromatography, high pressure liquid (194) 194
diclofenac - toxicity (193) 193
cells, cultured (191) 191
dosage and administration (190) 190
medicine, research & experimental (188) 188
aspirin (187) 187
biological availability (186) 186
delivery (185) 185
pain - drug therapy (185) 185
double-blind (182) 182
expression (182) 182
efficacy (178) 178
anti-inflammatory agents - pharmacology (177) 177
research article (174) 174
administration, topical (172) 172
liver (172) 172
acid (171) 171
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (6280) 6280
Russian (58) 58
German (53) 53
Japanese (41) 41
Spanish (24) 24
Chinese (21) 21
French (17) 17
Portuguese (11) 11
Croatian (6) 6
Czech (4) 4
Italian (4) 4
Polish (4) 4
Ukrainian (3) 3
Dutch (2) 2
Slovak (2) 2
Turkish (2) 2
Arabic (1) 1
Hungarian (1) 1
Korean (1) 1
Romanian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Chemical Research in Toxicology, ISSN 0893-228X, 09/2008, Volume 21, Issue 9, pp. 1814 - 1822
In vitro covalent binding assessments of drugs have been useful in providing retrospective insights into the association between drug metabolism and a... 
ACYL GLUCURONIDES | CHEMISTRY, MEDICINAL | PROTEIN | RAT | REACTIVE METABOLITES | TIENILIC ACID | HEPATIC-NECROSIS | BIOACTIVATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | TOXICOLOGY | HUMAN URINE | Buspirone - chemistry | Raloxifene Hydrochloride - pharmacology | Thiazoles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Indomethacin - metabolism | Simvastatin - pharmacology | Diclofenac - chemistry | Thiazines - metabolism | Propranolol - pharmacology | Toxicity Tests - methods | Binding Sites | Simvastatin - metabolism | Microsomes, Liver - chemistry | Indomethacin - pharmacology | Paroxetine - metabolism | Raloxifene Hydrochloride - metabolism | Triazoles - metabolism | Ticrynafen - metabolism | Paroxetine - pharmacology | Diclofenac - metabolism | Paroxetine - chemistry | Diphenhydramine - pharmacology | Diclofenac - pharmacology | Triazoles - chemistry | Buspirone - metabolism | Ticrynafen - pharmacology | Structure-Activity Relationship | Buspirone - pharmacology | Hepatocytes - metabolism | Dose-Response Relationship, Drug | Carbamazepine - chemistry | Diphenhydramine - metabolism | Acetaminophen - pharmacology | Microsomes, Liver - drug effects | Propranolol - metabolism | Carbamazepine - metabolism | Thiazines - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Hepatocytes - drug effects | Carbamazepine - pharmacology | Simvastatin - chemistry | Acetaminophen - chemistry | Ticrynafen - chemistry | Propranolol - chemistry | Diphenhydramine - chemistry | Thiazines - chemistry | Triazoles - pharmacology | Indomethacin - chemistry | Thiazoles - chemistry | Thiazoles - pharmacology | Raloxifene Hydrochloride - chemistry | Index Medicus
Journal Article
Journal Article
Brain Research, ISSN 0006-8993, 2010, Volume 1339, pp. 26 - 40
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2006, Volume 20, Issue 3, pp. 542 - 544
It is widely believed that the potencies of nonsteroid anti-inflammatory drugs ( NSAIDs) as inhibitors of cyclooxygenase ( COX) are influenced by protein... 
SITE | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | nonsteroid anti-inflammatory drugs | coxibs | PROSTAGLANDIN H-2 SYNTHASE | CELL BIOLOGY | CYCLO-OXYGENASE-2 | THERAPY | FLUID | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOLOGY | prostaglandins | SELECTIVITY | Organic Chemicals - cerebrospinal fluid | Humans | Naproxen - pharmacology | Synovial Fluid - metabolism | Pyrazoles - cerebrospinal fluid | Sodium Salicylate - pharmacology | Lactones - pharmacology | Aspirin - cerebrospinal fluid | Cell Line - drug effects | Calcium - physiology | Pyrazoles - blood | Organic Chemicals - pharmacology | Dinoprostone - cerebrospinal fluid | Diclofenac - cerebrospinal fluid | Aspirin - pharmacology | Sulfones - cerebrospinal fluid | Aspirin - blood | Thiazines - blood | Sulfonamides - pharmacology | Indomethacin - cerebrospinal fluid | Indomethacin - pharmacology | Cyclooxygenase 1 - drug effects | Cyclooxygenase Inhibitors - adverse effects | Cyclooxygenase Inhibitors - blood | Diclofenac - pharmacology | Thiazoles - blood | Thromboxane A2 - blood | Cerebrospinal Fluid Proteins - pharmacology | Dinoprostone - biosynthesis | Lactones - cerebrospinal fluid | Blood Platelets - enzymology | Cyclooxygenase 2 Inhibitors - cerebrospinal fluid | Sodium Salicylate - cerebrospinal fluid | Sulfones - pharmacology | Blood Proteins - pharmacology | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Naproxen - cerebrospinal fluid | Sodium Salicylate - blood | Thiazines - pharmacology | Cyclooxygenase 2 Inhibitors - blood | Cyclooxygenase Inhibitors - cerebrospinal fluid | Blood Platelets - drug effects | Sulfones - blood | Organic Chemicals - blood | Ionophores - pharmacology | Pyrazoles - pharmacology | Sulfonamides - cerebrospinal fluid | Cyclooxygenase 2 Inhibitors - pharmacology | Thiazoles - cerebrospinal fluid | Celecoxib | Diclofenac - blood | Dinoprostone - blood | Naproxen - blood | Organ Specificity | Calcimycin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Indomethacin - blood | Protein Binding | Thiazines - cerebrospinal fluid | Thiazoles - pharmacology
Journal Article
Biomacromolecules, ISSN 1525-7797, 09/2014, Volume 15, Issue 9, pp. 3246 - 3252
Multifunctional injectable thermo-/pH-responsive hydrogels as release systems for the oral delivery of small molecule drugs and the local delivery of protein... 
POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | COENZYME-A | MECHANICAL-PROPERTIES | BIODEGRADABLE HYDROGELS | IN-VITRO | CHITOSAN MATERIAL | PH | RECENT PROGRESS | SYSTEMS | BIOMEDICAL APPLICATIONS | ORAL DELIVERY | Diclofenac - pharmacology | Adipose Tissue - cytology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Delayed-Action Preparations - chemistry | Hydrogels - pharmacokinetics | Hydrogels - chemical synthesis | Hexuronic Acids - pharmacokinetics | Methacrylates - chemistry | Diclofenac - chemistry | Drug Carriers - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Adipose Tissue - metabolism | Mesenchymal Stromal Cells - cytology | Cattle | Delayed-Action Preparations - pharmacology | Delayed-Action Preparations - pharmacokinetics | Delayed-Action Preparations - chemical synthesis | Serum Albumin, Bovine - chemistry | Hexuronic Acids - chemical synthesis | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Glucuronic Acid - chemical synthesis | Alginates - pharmacology | Rabbits | Serum Albumin, Bovine - pharmacology | Mesenchymal Stromal Cells - metabolism | Drug Carriers - chemical synthesis | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Diclofenac - pharmacokinetics | Drug Carriers - pharmacology | Glucuronic Acid - pharmacology | Serum Albumin, Bovine - pharmacokinetics | Animals | Alginates - chemical synthesis | Alginates - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Drug Carriers - pharmacokinetics | Hydrogels - pharmacology | Hydrogels - chemistry | Hexuronic Acids - pharmacology | Hydrogen-Ion Concentration
Journal Article
Environment International, ISSN 0160-4120, 08/2019, Volume 129, pp. 320 - 332
Background: The presence of pharmaceuticals in the environment is a growing global concern and although environmental risk assessment is required for approval... 
POPULATION | ENVIRONMENTAL SCIENCES | CONSERVATION | PRIORITIZING PHARMACEUTICALS | BIOCONCENTRATION | DICLOFENAC | FISH | CHRONIC TOXICITY | RELEVANT CONCENTRATIONS | FATHEAD MINNOW | KIDNEY | Drugs | Proteins | Environmental aspects | Drug approval
Journal Article
Journal Article
European Journal of Pain (United Kingdom), ISSN 1090-3801, 04/2013, Volume 17, Issue 4, pp. 469 - 479
Background Injection of nerve growth factor (NGF) produces mechanical and thermal hypersensitivity in rodents and humans. Treatment with sequestering... 
ANTI-NGF | SODIUM-CHANNELS | ALLODYNIA | DIFFERENTIAL REGULATION | NEUROSCIENCES | CLINICAL NEUROLOGY | MUSCLE SENSITIZATION | PAIN | INTRAPLANTAR INJECTION | ANESTHESIOLOGY | HYPERALGESIA | PRIMARY SENSORY NEURONS | RECEPTORS | Hyperalgesia - chemically induced | Analgesics - pharmacology | Diclofenac - pharmacology | Pain Threshold - physiology | Sulfones - therapeutic use | Thiophenes - therapeutic use | Pyrazoles - therapeutic use | Male | Sulfones - pharmacology | Nerve Growth Factor | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | TRPV Cation Channels - antagonists & inhibitors | Amines - therapeutic use | Pain Threshold - drug effects | Behavior, Animal - drug effects | gamma-Aminobutyric Acid - therapeutic use | Pyrazoles - pharmacology | Pyridines - therapeutic use | Physical Stimulation | Analgesics - therapeutic use | Cyclohexanecarboxylic Acids - therapeutic use | Diclofenac - therapeutic use | Rats | Thiophenes - pharmacology | gamma-Aminobutyric Acid - pharmacology | Behavior, Animal - physiology | Celecoxib | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Hyperalgesia - physiopathology | Animals | Hyperalgesia - drug therapy | Sulfonamides - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Cyclohexanecarboxylic Acids - pharmacology | Duloxetine Hydrochloride | Pyridines - pharmacology | Amines - pharmacology
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 530, Issue 1, pp. 144 - 151
The mechanisms underlying transient receptor potential vanilloid receptor type 1 (TRPV1)-independent relaxation elicited by capsaicin were studied by measuring... 
Capsaicin | Intestine | Capsazepine | K + channel | Myosin light chain | channel | CELLS | intestine | GENE-RELATED PEPTIDE | MECHANISM | KINASE | VANILLOID RECEPTOR | TETRAETHYLAMMONIUM | RELEASE | K+ channel | SIGNAL-TRANSDUCTION | SMOOTH-MUSCLE | myosin light chain | INHIBITION | capsaicin | capsazepine | PHARMACOLOGY & PHARMACY | Diclofenac - pharmacology | Tetraethylammonium - pharmacology | Calcium - metabolism | Capsaicin - pharmacology | Potassium Channels - physiology | Dimethyl Sulfoxide - pharmacology | Male | Peptide Fragments - pharmacology | Apamin - pharmacology | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Ileum - drug effects | Glyburide - pharmacology | Piperidines - pharmacology | Charybdotoxin - pharmacology | Potassium Chloride - pharmacology | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Caffeine - pharmacology | Muscle, Smooth - physiology | Phosphorylation - drug effects | Benzopyrans - pharmacology | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | Pyrazoles - pharmacology | Diterpenes - pharmacology | Guinea Pigs | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Calcitonin Gene-Related Peptide - pharmacology | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Phosphodiesterase Inhibitors - pharmacology | Capsaicin - analogs & derivatives | Papaverine - pharmacology | Barium - pharmacology | Nitroarginine - pharmacology | Animals | Ileum - physiology | Myosin Light Chains - metabolism | Capsaicin - antagonists & inhibitors | Muscle Relaxation - drug effects | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | In Vitro Techniques | Guanethidine - pharmacology | Acetylcholine | Peptides | Glibenclamide | Muscle proteins | Myosin
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2001, Volume 345, Issue 25, pp. 1809 - 1817
Journal Article