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PLoS ONE, ISSN 1932-6203, 2017, Volume 12, Issue 7, p. e0181357
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 20, pp. 4831 - 4838
Journal Article
Journal Article
BioMetals, ISSN 0966-0844, 6/2016, Volume 29, Issue 3, pp. 389 - 397
HIV infection is known for replicating in proliferating CD+ T-cells. Treatment of these cells with cytostatic (anti-proliferation) compounds such as... 
Life Sciences | Biochemistry, general | HIV-1 | Microbiology | Cytostatic | Chloroquine | Gold complexes | Plant Physiology | Virostatic | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | ENTRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROXYUREA | FUSION INHIBITOR T-20 | GP120 | CELL-LINES | REPLICATION | DIDANOSINE | IMMUNODEFICIENCY-VIRUS TYPE-1 | RESISTANCE | Anti-HIV Agents - pharmacology | Phosphines - pharmacology | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Anti-HIV Agents - chemical synthesis | Quinolines - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Phosphines - chemistry | Ferrous Compounds - pharmacology | Ferrous Compounds - chemistry | Molecular Structure | Organogold Compounds - chemistry | Gold - chemistry | Cell Line | Cell Survival - drug effects | Organogold Compounds - chemical synthesis | HIV-1 - drug effects | HIV Infections - virology | Quinolines - chemistry | Models, Molecular | Gold - pharmacology | Anti-HIV Agents - chemistry | Organogold Compounds - pharmacology | HIV Infections - drug therapy | Gold | Pharmacology | Cellular biology | Human immunodeficiency virus--HIV | Index Medicus | Basic Medicine | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biokemi och molekylärbiologi | Medicinska och farmaceutiska grundvetenskaper | Biochemistry and Molecular Biology | Farmakologi och toxikologi | Biologi | Natural Sciences | Pharmacology and Toxicology
Journal Article
AIDS, ISSN 0269-9370, 11/2004, Volume 18, Issue 16, pp. 2127 - 2136
Journal Article
Antiviral Research, ISSN 0166-3542, 2002, Volume 54, Issue 1, pp. 37 - 45
Clinical studies with tenofovir disoproxil fumarate, an oral prodrug of the nucleotide analog tenofovir, recently approved for the treatment of HIV, have... 
Tenofovir | Cytotoxicity | Nucleoside reverse transcriptase inhibitors (NRTI) | Hematopoiesis | MITOCHONDRIAL TOXICITY | 2',3'-DIDEOXYCYTIDINE | CONTROLLED TRIAL | tenofovir | IMMUNODEFICIENCY-VIRUS-INFECTION | ANTIRETROVIRAL THERAPY | hematopoiesis | ALTERS GLYCOSPHINGOLIPID SYNTHESIS | HEMATOPOIETIC PROGENITOR CELLS | VIROLOGY | PHARMACOKINETICS | AIDS-RELATED COMPLEX | nucleoside reverse transcriptase inhibitors (NRTI) | PHARMACOLOGY & PHARMACY | PHASE-I | cytotoxicity | Anti-HIV Agents - pharmacology | Antigens, CD34 | Zalcitabine - toxicity | Reverse Transcriptase Inhibitors - toxicity | Anti-HIV Agents - toxicity | Epithelial Cells - drug effects | Humans | Didanosine - pharmacology | Reverse Transcriptase Inhibitors - pharmacology | Zalcitabine - pharmacology | Muscle, Skeletal - cytology | Adenine - chemistry | Reverse Transcriptase Inhibitors - chemistry | Stavudine - pharmacology | Organophosphorus Compounds - pharmacology | Tumor Cells, Cultured | Epithelial Cells - cytology | Hematopoietic Stem Cells - drug effects | Cell Line | Dideoxynucleosides - pharmacology | Kidney Tubules, Proximal - cytology | Adenine - analogs & derivatives | Dideoxynucleosides - toxicity | Zidovudine - pharmacology | Organophosphorus Compounds - chemistry | Adenine - pharmacology | Adenine - toxicity | Organophosphonates | Stavudine - toxicity | Anti-HIV Agents - chemistry | Hematopoietic Stem Cells - cytology | Zidovudine - toxicity | Didanosine - toxicity | Liver - cytology | Organophosphorus Compounds - toxicity
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2006, Volume 12, Issue 5, pp. 1547 - 1555
The increased expression of markers associated with a differentiated phenotype, such as P-glycoprotein (Pgp), follows treatment with histone deacetylase... 
MDR1 | ATP-dependent transporters and drug resistance | histone deacetylase inhibitor | BREAST-CANCER CELLS | HISTONE DEACETYLASE INHIBITOR | ADVANCED SOLID TUMORS | ONCOLOGY | SUBEROYLANILIDE HYDROXAMIC ACID | PHASE-I TRIAL | SODIUM-BUTYRATE | CHRONIC LYMPHOCYTIC-LEUKEMIA | P-GLYCOPROTEIN EXPRESSION | THYROID-CARCINOMA CELLS | MULTIDRUG-RESISTANCE | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Leukocytes, Mononuclear - metabolism | Paclitaxel - pharmacology | Antibiotics, Antineoplastic - pharmacology | Drug Resistance, Multiple | Colonic Neoplasms - drug therapy | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Didanosine - pharmacology | Neoplastic Cells, Circulating - metabolism | Drug Resistance, Neoplasm | Depsipeptides - pharmacology | Kidney Neoplasms - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Colonic Neoplasms - metabolism | Kidney - metabolism | Flow Cytometry | ATP-Binding Cassette Transporters - genetics | Hippocalcin - pharmacology | ATP-Binding Cassette Transporters - metabolism | Sezary Syndrome - drug therapy | Multidrug Resistance-Associated Proteins - genetics | Antineoplastic Agents - pharmacology | Acetylation | Tumor Cells, Cultured | Carcinoma, Renal Cell - drug therapy | Neoplasm Proteins - genetics | Antimetabolites - pharmacology | Kidney - drug effects | RNA, Messenger - genetics | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Renal Cell - metabolism | Sezary Syndrome - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Histones - metabolism | Kidney Neoplasms - drug therapy | Multidrug Resistance-Associated Proteins - metabolism | Doxorubicin - pharmacology
Journal Article
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 12/2012, Volume 19, Issue 35, pp. 5924 - 5939
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 4/2011, Volume 50, Issue 4, pp. 229 - 244
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 1, p. e85637
Nucleoside analogue reverse transcriptase inhibitor (NRTI), an integral component of highly active antiretroviral therapy (HAART), was widely used to inhibit... 
HIV/AIDS | REVERSE-TRANSCRIPTASE INHIBITORS | MULTIDISCIPLINARY SCIENCES | ACTIVE ANTIRETROVIRAL THERAPY | LACTIC-ACIDOSIS | TOXICITY | DYSFUNCTION | HYPERLACTATEMIA | CAPTURE | BRAIN | GENOME | DNA, Mitochondrial - metabolism | Liver - metabolism | Cells, Cultured | Didanosine - pharmacology | Zidovudine - pharmacology | Muscle, Skeletal - metabolism | Neurons - cytology | Mitochondria - metabolism | Mitochondria - drug effects | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Animals | Liver - drug effects | Muscle, Skeletal - drug effects | Stavudine - pharmacology | Lamivudine - pharmacology | Mice | Neurons - metabolism | Cerebral Cortex - drug effects | Neurons - drug effects | Antimetabolites - pharmacology | Highly active antiretroviral therapy | Antiviral agents | Brain | Neurons | Nucleosides | DNA polymerases | Mitochondrial DNA | RNA-directed DNA polymerase | Toxicity | Cardiomyopathy | Liver | Central nervous system | Stavudine | Glial cells | Polyneuropathy | Neuronal-glial interactions | Neurotoxicity | Blood-brain barrier | Acquired immune deficiency syndrome--AIDS | Clonal deletion | Antiretroviral agents | Animal tissues | Human immunodeficiency virus--HIV | Deletion | Lactic acidosis | Deoxyribonucleic acid--DNA | Antiretroviral drugs | Cortex | Muscles | Lamivudine | Exposure | Lipoatrophy | Didanosine | Acidosis | Zidovudine | Nucleoside analogs | Myopathy | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | DNA | Human immunodeficiency virus
Journal Article