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1. Full Text Protein-Restricted Diet Regulates Lipid and Energy Metabolism in Skeletal Muscle of Growing Pigs
by Li, Yinghui and Li, Fengna and Chen, Shuai and Duan, Yehui and Guo, Qiuping and Wang, Wenlong and Wen, Chaoyue and Yin, Yulong
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 12/2016, Volume 64, Issue 49, pp. 9412 - 9420
The aim of this work was to study the lipid metabolism and energy status of skeletal muscle of pigs as affected by dietary protein restriction. Eighteen... 
protein restriction | fat | growing pigs | energy status | skeletal muscle | CELLS | ACID-SUPPLEMENTED DIETS | MEAT QUALITY | FOOD SCIENCE & TECHNOLOGY | KINASE | SIRT1 | GROWTH-PERFORMANCE | CRUDE PROTEIN | CARCASS CHARACTERISTICS | AGRICULTURE, MULTIDISCIPLINARY | MITOCHONDRIAL DYSFUNCTION | CHEMISTRY, APPLIED | INTRAMUSCULAR FAT-CONTENT | Sirtuin 1 - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | AMP-Activated Protein Kinases - metabolism | Swine - metabolism | Muscle, Skeletal - growth & development | Lipid Metabolism | Muscle, Skeletal - metabolism | Swine - genetics | Swine - growth & development | Sirtuin 1 - genetics | Diet, Protein-Restricted | Dietary Proteins - metabolism | Animals | Animal Feed - analysis | Energy Metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | AMP-Activated Protein Kinases - genetics
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2. Full Text Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications
by Lillycrop, Karen A and Slater-Jefferies, Jo L and Hanson, Mark A and Godfrey, Keith M and Jackson, Alan A and Burdge, Graham C
British Journal of Nutrition, ISSN 0007-1145, 6/2007, Volume 97, Issue 6, pp. 1064 - 1073
Prenatal nutritional constraint induces an altered metabolic phenotype in the offspring which in humans confers an increased risk of non-communicable disease.... 
Human | Histones | Epigenetic | Rat | Fetal programming | Glucocorticoid receptor | FETAL EXPOSURE | IN-UTERO | glucocorticoid receptor | DNMT1 | rat | epigenetic | fetal programming | SUPPLEMENTATION | PHOSPHOENOLPYRUVATE CARBOXYKINASE | NUTRITION & DIETETICS | histones | SYSTOLIC BLOOD-PRESSURE | MESSENGER-RNA | GENE | XENOPUS EMBRYOS | human | BINDING | Prenatal Exposure Delayed Effects | Maternal Nutritional Physiological Phenomena | Rats, Wistar | Fetal Nutrition Disorders - metabolism | Methyl-CpG-Binding Protein 2 - metabolism | Fetal Nutrition Disorders - genetics | Receptors, Glucocorticoid - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | Epigenesis, Genetic - physiology | DNA Methylation | Umbilical Cord - metabolism | Gene Expression Regulation, Developmental | Female | Fetal Development - genetics | Acetylation | Promoter Regions, Genetic | DNA (Cytosine-5-)-Methyltransferase 1 | Liver - metabolism | Rats | Diet, Protein-Restricted | Pregnancy | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Receptors, Glucocorticoid - genetics | Histones - metabolism | Proteins | Nutrition | Diet | Neurons | Genes | Rodents | Genetics | Metabolic disorders | Deoxyribonucleic acid--DNA
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3. Regulatory role of amino acids in pigs fed on protein-restricted diets
by Kim, Sung Woo and Chen, Hongyu and Parnsen, Wanpuech
Current Protein and Peptide Science, ISSN 1389-2037, 2019, Volume 20, Issue 2, pp. 132 - 138
The high inclusion of dietary protein and the imbalance of amino acid (AA) composition in animal husbandry result in inefficient utilization of protein... 
Pigs | Dietary protein | Protein-restricted diet | Nutrient requirement | Amino acid | Ideal amino acid profile | Diet, Protein-Restricted | Amino Acids - metabolism | Dietary Proteins - metabolism | Nitrogen - metabolism | Animal Husbandry - methods | Animals | Animal Nutritional Physiological Phenomena | Swine | Dietary Supplements | Excretion | Nutrient deficiency | Dietary supplements | Amino acid composition | Amino acids | Metabolism | Nitrogen | Breeding of animals | Protein turnover | Proteins | Diet | Regulatory mechanisms (biology) | Husbandry | Supplementation | High protein diet
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4. Regulatory Role of Ammo Acids in Pigs Fed on Protein-restricted Diets
by Kim, SW and Chen, HY and Parnsen, W
CURRENT PROTEIN & PEPTIDE SCIENCE, ISSN 1389-2037, 2019, Volume 20, Issue 2, pp. 132 - 138
The high inclusion of dietary protein and the imbalance of amino acid (AA) composition in animal husbandry result in inefficient utilization of protein... 
LIPID-METABOLISM | protein-restricted diet | BIOCHEMISTRY & MOLECULAR BIOLOGY | ARGININE SUPPLEMENTATION | BARRIER FUNCTION | GRADE L-METHIONINE | GUT MICROBIOTA | ideal amino acid profile | GROWTH-PERFORMANCE | pigs | Amino acid | ILEAL DIGESTIBLE TRYPTOPHAN | AMINO-ACIDS | LEUCINE SUPPLEMENTATION | dietary protein | nutrient requirement | NURSERY PIGS
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5. Full Text Protein-restricted diets for ameliorating motor fluctuations in Parkinson's disease
by Wang, Luxi and Xiong, Nian and Huang, Jinsha and Guo, Shiyi and Liu, Ling and Han, Chao and Zhang, Guoxin and Jiang, Haiyang and Ma, Kai and Xia, Yun and Xu, Xiaoyun and Li, Jie and Liu, Jing Y and Wang, Tao
Frontiers in Aging Neuroscience, ISSN 1663-4365, 06/2017, Volume 9
Levodopa is considered to be the most effective symptomatic drug for Parkinson's disease (PD). As the disease progresses, however, the patients are likely to... 
Diet therapy | Parkinson's disease | Levodopa | Fluctuation | Protein | ANTIPARKINSONIAN RESPONSE | NEUROSCIENCES | REDISTRIBUTION DIET | GERIATRICS & GERONTOLOGY | ENTERAL NUTRITION | PLASMA | levodopa | AMINO-ACIDS | protein | L-DOPA | POSITRON EMISSION TOMOGRAPHY | COMPLICATIONS | fluctuation | CLINICAL-RESPONSE | diet therapy | Competition | Nutrient deficiency | Dopamine | Calcium | Neurodegenerative diseases | Parkinsons disease | Amino acids | Bioavailability | Small intestine | Proteins | Body mass index | Neurology | Side effects | Older people | Malnutrition | Meals | Low protein diet | Drug dosages | Movement disorders | Dyskinesia
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6. Full Text Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring
by Lillycrop, Karen A and Phillips, Emma S and Torrens, Christopher and Hanson, Mark A and Jackson, Alan A and Burdge, Graham C
British Journal of Nutrition, ISSN 0007-1145, 8/2008, Volume 100, Issue 2, pp. 278 - 282
Induction of an altered phenotype by prenatal under-nutrition involves changes in the epigenetic regulation of specific genes. We investigated the effect of... 
Rats | Epigenetic regulation | PPARα | Fetal programming | DNMT1 | TRANSCRIPTION | PPAR alpha | MATERNAL-BEHAVIOR | fetal programming | GENERATIONS | epigenetic regulation | RESPONSES | NUTRITION & DIETETICS | rats | RECEPTORS | STRESS | EXPRESSION | Promoter Regions, Genetic | Epigenesis, Genetic | Liver - metabolism | Molecular Sequence Data | PPAR alpha - genetics | Prenatal Nutritional Physiological Phenomena - genetics | Diet, Protein-Restricted | Pregnancy | Prenatal Exposure Delayed Effects - genetics | DNA Methylation | Animals | Cytosine - metabolism | Base Sequence | Reverse Transcriptase Polymerase Chain Reaction - methods | CpG Islands | Female | Fetal Development - genetics | rat | epigenetic
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7. Full Text Renal sodium handling and blood pressure changes in gestational protein-restricted offspring: Role of renal nerves and ganglia neurokinin expression
by Custódio, Augusto H and De Lima, Marcelo C and Vaccari, Bárbara and Boer, Patrícia A and Gontijo, José A. R
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0179499
Background Considering long-term changes in renal sodium handling and blood pressure in maternal protein-restricted (LP) offspring, we assumed that the... 
AFFERENT NEURONS | GENE-RELATED PEPTIDE | SPONTANEOUSLY HYPERTENSIVE-RATS | RENIN-ANGIOTENSIN SYSTEM | DENERVATION ABOLISHES | MULTIDISCIPLINARY SCIENCES | INHIBITORY RENORENAL REFLEXES | NITRIC-OXIDE | KIDNEY | SENSORY RECEPTORS | SUBSTANCE-P RECEPTOR | Kidney - physiology | Rats, Wistar | Potassium - analysis | Kidney Pelvis - metabolism | Rats | Calcitonin Gene-Related Peptide - genetics | Male | Sodium - metabolism | Lithium - analysis | Diet, Protein-Restricted | Creatinine - metabolism | Neurokinin A - metabolism | Animals | Sodium - analysis | Lithium - metabolism | Catecholamines - analysis | Substance P - genetics | Female | Substance P - metabolism | Blood Pressure - physiology | Neurokinin A - genetics | Calcitonin Gene-Related Peptide - metabolism | Microscopy, Fluorescence | Ganglia, Spinal - metabolism | Sensory receptors | Physiological aspects | Sodium in the body | Genetic aspects | Blood pressure | Research | Ganglia | Renal function | Staining | Lithium | Clearances | Confocal | Pelvis | Blood | Proteins | Receptors | Functional anatomy | Dorsal root ganglia | Newborn babies | Neurokinin | Lasers | Surgery | Nerves | Attenuation | Low protein diet | Hypertension | Creatinine | Medical research | Excretion | Dams | Kidneys | Neurons | Reabsorption | Pregnancy | Rejection | Calcitonin gene-related peptide | Progeny | Offspring | Sodium | Immunofluorescence | Denervation
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8. Full Text Taurine supplementation reduces blood pressure and prevents endothelial dysfunction and oxidative stress in post-weaning protein-restricted rats
by Maia, Aline R and Maia, Aline R and Batista, Thiago M and Batista, Thiago M and Victorio, Jamaira A and Victorio, Jamaira A and Clerici, Stefano P and Clerici, Stefano P and Delbin, Maria A and Delbin, Maria A and Carneiro, Everardo M and Carneiro, Everardo M and Davel, Ana P and Davel, Ana P
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e105851
Introduction: Taurine is a sulfur-containing amino acid that exerts protective effects on vascular function and structure in several models of cardiovascular... 
NADPH OXIDASE | HOMOCYSTEINE | DIET | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | DECREASE | SECRETION | HYPERTENSION | SUPEROXIDE-DISMUTASE | EXPRESSION | BAROREFLEX | Reactive Oxygen Species - metabolism | Rats, Wistar | Weaning | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Male | Heart Rate - drug effects | Aorta, Thoracic - physiology | Acetophenones - pharmacology | Blood Pressure - drug effects | Aorta, Thoracic - drug effects | Nitric Oxide Synthase Type III - metabolism | Superoxide Dismutase - metabolism | Superoxide Dismutase - pharmacology | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Endothelium, Vascular - physiopathology | Blotting, Western | Diet, Protein-Restricted | Animals | Endothelium, Vascular - metabolism | Taurine - administration & dosage | Oxidative Stress - drug effects | Taurine - pharmacology | Vasodilation - drug effects | In Vitro Techniques | Nitric Oxide - metabolism | Dietary Supplements | Drinking water | Oxidative stress | Reactive oxygen species | Phosphorylation | Homeostasis | Amino acids | Superoxide dismutase | Biology | Remodeling | Blood | NAD(P)H oxidase | Rings (mathematics) | Proteins | Antioxidants | Restoration | Rodents | Aorta | Blood pressure | Malnutrition | Sulfur | Heart diseases | Low protein diet | Hypertension | Cardiovascular system | Nutrient deficiency | Antiinflammatory agents | Incubation | Dietary supplements | Rats | Thorax | Inflammation | Bioavailability | Metabolism | Catheters | Nitric-oxide synthase | Endothelium | Diet | Nitric oxide | Coronary vessels | Acetylcholine | Diabetes | Laboratory animals | Cardiovascular diseases | Homocysteine
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9. Full Text Whole Body Protein Oxidation Unaffected after a Protein Restricted Diet in Healthy Young Males
by Reckman, Gerlof A R and Reckman, Gerlof A. R and Navis, Gerjan J and Navis, Gerjan J and Krijnen, Wim P and van der Schans, Cees P and van der Schans, Cees P and Vonk, Roel J and Vonk, Roel J and Jager-Wittenaar, Harriët and Jager-Wittenaar, Harriët
Nutrients, ISSN 2072-6643, 01/2019, Volume 11, Issue 1, p. 115
Protein oxidation may play a role in the balance between anabolism and catabolism. We assessed the effect of a protein restricted diet on protein oxidation as... 
anabolic competence | Naturally enriched | breath test | naturally enriched 13C-milk proteins | oxidation | C-milk proteins | Protein | MALNUTRITION | NUTRITION & DIETETICS | NITROGEN | HUMANS | naturally enriched C-13-milk proteins | LEUCINE | CONSUMPTION | Nephrology | Body weight | Breath tests | Variations | Amino acids | Systematic review | Males | Isotope ratios | Body composition | Protein turnover | Proteins | Ureas | Oxidation | Food | Milk | Urine | Creatinine | Carbohydrates | Protein metabolism | Nutrient deficiency | Internal medicine | Mass spectroscopy | Dietary intake | Metabolism | Nitrogen | Nutrition research | Urea | Diet | Protein synthesis | Catabolism | Diabetes | Mass spectrometry
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10. Full Text Protein-Restricted Diets for Ameliorating Motor Fluctuations in Parkinson's Disease
by Wang, Luxi and Xiong, Nian and Huang, Jinsha and Guo, Shiyi and Liu, Ling and Han, Chao and Zhang, Guoxin and Jiang, Haiyang and Ma, Kai and Xia, Yun and Xu, Xiaoyun and Li, Jie and Liu, Jing Y and Wang, Tao
Frontiers in aging neuroscience, ISSN 1663-4365, 2017, Volume 9, p. 206
Levodopa is considered to be the most effective symptomatic drug for Parkinson's disease (PD). As the disease progresses, however, the patients are likely to... 
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11. Full Text Dietary protein and lifespan across the metamorphic boundary: Protein-restricted larvae develop into short-lived adults
by Runagall-Mcnaull, A and Bonduriansky, R and Crean, A.J
Scientific Reports, ISSN 2045-2322, 06/2015, Volume 5, Issue 1, p. 11783
Restriction of nutrients in the adult diet extends lifespan across a diverse range of species, but less is known about the long-term effects of developmental... 
RESOURCE-ALLOCATION | FIELD CRICKETS | TRADE-OFF | TELOSTYLINUS-ANGUSTICOLLIS DIPTERA | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | EXTENSION | MECHANISMS | SEXUAL SELECTION | REPRODUCTION | FOOD | Dietary Proteins - administration & dosage | Metamorphosis, Biological - physiology | Body Size - drug effects | Longevity - drug effects | Male | Animal Nutritional Physiological Phenomena - drug effects | Animals | Time Factors | Larva - drug effects | Body Size - physiology | Dietary Proteins - pharmacology | Diptera - drug effects | Diptera - physiology | Female | Larva - physiology | Longevity - physiology | Metamorphosis, Biological - drug effects | Proteins | Dietary restrictions | Diet | Life span | Body size | Nutrients | Protein sources | Long-term effects
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12. Full Text Protein restricted diet during gestation and/or lactation in mice affects 15N natural isotopic abundance of organs in the offspring: Effect of diet 15N content and growth
by Bernardo, Karine and Jousse, Céline and Fafournoux, Pierre and Schiphorst, Anne-Marie and Grand, Mathilde and Robins, Richard J and Hankard, Régis and De Luca, Arnaud
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 10, p. e0205271
This study aimed at measuring the effect in normal to restricted protein diets with specific 15N natural isotopic abundance (NIA) given during gestation and/or... 
Growth rate | Disease | Lactation | Weaning | Liver | Amino acids | Biosynthesis | Gestation | Proteins | Rodents | Low protein diet | Food | Hair | Nutrient deficiency | Organs | Muscles | Exponential functions | Metabolism | Nitrogen | Variance analysis | Carbon | Nutrition research | Progeny | Offspring | Dilution | Animals | Diet | Mice | Scientific imaging | Life Sciences | Food and Nutrition | Santé publique et épidémiologie
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13. Full Text ITRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins
by Liu, Xiaomei and Wang, Jun and Gao, Linlin and Liu, Hao and Liu, Caixia
Cellular Physiology and Biochemistry, ISSN 1015-8987, 11/2017, Volume 44, Issue 1, pp. 185 - 199
Background: It is well recognized that adverse events in utero can impair fetal development and lead to the development of kidney injury and hypertension in... 
iTRAQ | Offspring | Prenatal nutrition | IUGR | Kidney | OXIDATIVE STRESS | PHYSIOLOGY | LOW-BIRTH-WEIGHT | BLOOD-PRESSURE | GENOME | CELL BIOLOGY | EMBRYONIC STEM-CELLS | DISEASE | SYMPATHETIC-NERVE ACTIVITY | INTRAUTERINE GROWTH RESTRICTION | HYPERTENSION | FOR-GESTATIONAL-AGE | Animals, Newborn | Up-Regulation | Histone-Lysine N-Methyltransferase - genetics | Rats, Wistar | Purines - metabolism | Down-Regulation | Oxidative Phosphorylation | Rats | Fetal Growth Retardation - metabolism | Proteome - analysis | Pyrimidines - metabolism | TRPP Cation Channels - genetics | Diet, Protein-Restricted | Carrier Proteins - genetics | Kidney - metabolism | Animals | Carrier Proteins - metabolism | Histones - genetics | Histone-Lysine N-Methyltransferase - metabolism | Fetal Growth Retardation - etiology | Databases, Protein | Proteomics | Histones - metabolism | TRPP Cation Channels - metabolism
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14. Full Text Preovulatory exposure to a protein-restricted diet disrupts amino acid kinetics and alters mitochondrial structure and function in the rat oocyte and is partially rescued by folic acid
by Schutt, AK and Blesson, CS and Hsu, JW and Valdes, CT and Gibbons, WE and Jahoor, F and Yallampalli, C
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, ISSN 1477-7827, 01/2019, Volume 17, Issue 1, pp. 12 - 13
BackgroundDetrimental exposures during pregnancy have been implicated in programming offspring to develop permanent changes in physiology and metabolism,... 
OXIDATIVE STRESS | MATERNAL OBESITY | Developmental programming | SEVERE CHILDHOOD UNDERNUTRITION | GLUCOSE-TRANSPORT | Metabolism | PREGNANCY | Mitochondria | REPRODUCTIVE BIOLOGY | Amino acid | ENDOCRINOLOGY & METABOLISM | EPIGENETIC REGULATION | GENE-EXPRESSION | NUTRITION | Kinetics | FISSION | Protein restriction | Oocyte | Follicular Phase | Microscopy, Electron, Transmission | Folic Acid - pharmacology | Gene Expression - drug effects | Rats, Wistar | Oocytes - metabolism | Mitochondria - metabolism | Mitochondria - ultrastructure | Diet, Protein-Restricted | Amino Acids - metabolism | Animals | Cumulus Cells - cytology | Cumulus Cells - metabolism | Oocytes - drug effects | Female | Vitamin B Complex | Hypertension | Medical research | Cysteine | Heart diseases in pregnancy | Liver | Dietary supplements | Folic acid | Cystine | Pregnancy | Diet | Physiological aspects | Medicine, Experimental | Heart diseases | Oxidative stress | Serine | Erythrocytes | Amino acids | Cardiovascular disease | Protein turnover | Oocytes | Proteins | Glucose metabolism | Famine | Ultrastructure | Cell cycle | DNA methylation | Physiology | Malnutrition | Deoxyribonucleic acid--DNA | Glutathione | Obesity | Nutrient deficiency | Catheterization | Diabetes mellitus | Methionine | Gene expression | Glucose transport | Embryos | Carbon | Coronary artery disease | Investigations | Hepatocytes | Epigenetics | Insulin resistance | Intubation | Diabetes | Electron transport | Apoptosis | Tracers | Structure-function relationships
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