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1. Full Text Increase in plasma endotoxin concentrations and the expression of toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: Implications for insulin resistance
by Ghanim, Husam and Abuaysheh, Sanaa and Sia, Ching Ling and Korzeniewski, Kelly and Chaudhuri, Ajay and Fernandez-Real, Jose Manuel and Dandona, Paresh
Diabetes Care, ISSN 0149-5992, 12/2009, Volume 32, Issue 12, pp. 2281 - 2287
OBJECTIVE - To compare the effect of a high-fat, high-carbohydrate meal (HFHC) with that of a high-fiber and fruit meal on the concentrations of endotoxin... 
METABOLIC SYNDROME | ACTIVATION | PROINFLAMMATORY STATE | OBESE SUBJECTS | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | SENSITIVITY | MONOCYTES | FACTOR-KAPPA-B | MICE | ADIPOSE-TISSUE | Endotoxins - blood | Toll-Like Receptor 2 - genetics | Humans | Middle Aged | Male | Reference Values | Insulin - blood | Young Adult | Lipopolysaccharides - blood | Suppressor of Cytokine Signaling Proteins - blood | Dietary Fats - pharmacology | Insulin Resistance - physiology | Adult | Dietary Fiber | Female | Fruit | Dietary Carbohydrates - pharmacology | Suppressor of Cytokine Signaling Proteins - genetics | Toll-Like Receptor 4 - genetics | Thiobarbituric Acid Reactive Substances - metabolism | Suppressor of Cytokine Signaling 3 Protein | Toll-Like Receptor 4 - blood | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - blood | Oxidative Stress - drug effects | Blood Glucose - metabolism | Endotoxins - pharmacology | Care and treatment | Cytokines | High-carbohydrate diet | Endotoxins | Physiological aspects | Insulin resistance | Research | Health aspects | Plasma | Carbohydrates | Diabetes | Meals | Dietary fiber | Insulin | Index Medicus | Original Research
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2. Full Text Carbohydrate sensing in the human mouth: effects on exercise performance and brain activity
by E. S. Chambers and M. W. Bridge and D. A. Jones
The Journal of Physiology, ISSN 0022-3751, 04/2009, Volume 587, Issue 8, pp. 1779 - 1794
Exercise studies have suggested that the presence of carbohydrate in the human mouth activates regions of the brain that can enhance exercise performance but... 
HEDONIC EXPERIENCE | PHYSIOLOGY | MUSCLE GLYCOGEN | TRIAL CYCLING PERFORMANCE | ENDURANCE PERFORMANCE | GLUCOSE KINETICS | 1-H TIME TRIAL | ELECTROLYTE FEEDINGS | UMAMI TASTE | ORBITOFRONTAL CORTEX | NEUROSCIENCES | PREFRONTAL CORTEX | Brain - anatomy & histology | Sweetening Agents - pharmacology | Dietary Carbohydrates - pharmacology | Anaerobic Threshold - drug effects | Humans | Male | Glucose - pharmacology | Taste - physiology | Brain - physiology | Oxygen Consumption - physiology | Polysaccharides - pharmacology | Young Adult | Magnetic Resonance Imaging | Exercise Test | Mouth - physiology | Heart Rate - physiology | Adult | Female | Exercise - physiology | Saccharin - pharmacology | Cyclists | Glucose | Dextrins | Dextrose | Index Medicus | Skeletal Muscle and Exercise
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3. Full Text A Resveratrol and Polyphenol Preparation Suppresses Oxidative and Inflammatory Stress Response to a High-Fat, High-Carbohydrate Meal
by Ghanim, Husam and Sia, Chang Ling and Korzeniewski, Kelly and Lohano, Teekam and Abuaysheh, Sanaa and Marumganti, Anuritha and Chaudhuri, Ajay and Dandona, Paresh
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2011, Volume 96, Issue 5, pp. 1409 - 1414
A supplement containing resveratrol and muscadine polyphenols prior to a high-fat high-carbohydrate meal significantly reduced multiple indices of oxidative... 
ACTIVATION | ACID | NRF2 | ENDOCRINOLOGY & METABOLISM | MONONUCLEAR-CELLS | RESISTANCE | SOCS-3 | DYSFUNCTION | Inflammation - chemically induced | Fallopia japonica - chemistry | Toll-Like Receptor 4 - biosynthesis | Vitis - chemistry | Plant Extracts - pharmacology | Humans | Male | Stilbenes - pharmacology | Inflammation - metabolism | Polyphenols | Adult | DNA - biosynthesis | Female | Flavonoids - pharmacology | Lipopolysaccharide Receptors - biosynthesis | Phenols - pharmacology | Dietary Fats - adverse effects | Dietary Carbohydrates - pharmacology | Antioxidants - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | DNA - genetics | Suppressor of Cytokine Signaling 3 Protein | Lipopolysaccharides - pharmacology | Inflammation - prevention & control | Oxidative Stress - drug effects | NF-E2-Related Factor 2 - biosynthesis | Suppressor of Cytokine Signaling Proteins - biosynthesis | Cytokines - biosynthesis | Index Medicus | Abridged Index Medicus | 100 | 500 | Endocrine Research
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4. Full Text Fermentable carbohydrate restriction reduces luminal bifidobacteria and gastrointestinal symptoms in patients with irritable bowel syndrome
by Staudacher, Heidi M and Lomer, Miranda C. E and Anderson, Jacqueline L and Barrett, Jacqueline S and Muir, Jane G and Irving, Peter M and Whelan, Kevin
Journal of Nutrition, ISSN 0022-3166, 08/2012, Volume 142, Issue 8, pp. 1510 - 1518
Preliminary studies indicate that dietary restriction of fermentable short-chain carbohydrates improves symptoms in irritable bowel syndrome (IBS). Prebiotic... 
HEALTHY HUMANS | DIETARY-MANAGEMENT | BACTERIA | NUTRITION & DIETETICS | ANTIBIOTIC PERTURBATION | CHAIN FATTY-ACIDS | DENDRITIC CELL | FECAL MICROBIOTA | CLINICAL-TRIALS | DISEASE | GUT MICROBIOTA | Dietary Carbohydrates - administration & dosage | Fatty Acids - chemistry | Dietary Carbohydrates - pharmacology | Irritable Bowel Syndrome - diet therapy | Humans | Middle Aged | Male | Fermentation | Young Adult | Feces - microbiology | Bifidobacterium - drug effects | Food Analysis | Diet | Irritable Bowel Syndrome - pathology | Adult | Female | Prevention | Low-carbohydrate diet | Health aspects | Irritable bowel syndrome | Index Medicus
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5. Full Text Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome
by Major, Giles and Pritchard, Sue and Murray, Kathryn and Alappadan, Jan Paul and Hoad, Caroline L and Marciani, Luca and Gowland, Penny and Spiller, Robin
Gastroenterology, ISSN 0016-5085, 2017, Volume 152, Issue 1, pp. 124 - 133.e2
Background & Aims Poorly digested, fermentable carbohydrates may induce symptoms of irritable bowel syndrome (IBS) via unclear mechanisms. We performed a... 
Gastroenterology and Hepatology | Fermentation | MRI | FODMAP | Bloating | FODMAPS REDUCES SYMPTOMS | HEALTHY-SUBJECTS | LACTOSE-INTOLERANCE | TRANSIT-TIME | DIET LOW | FRUCTOSE | INGESTION | WATER-CONTENT | MALABSORPTION | GASTROENTEROLOGY & HEPATOLOGY | Area Under Curve | Humans | Middle Aged | Male | Dietary Carbohydrates - metabolism | Case-Control Studies | Fructose - metabolism | Inulin - pharmacology | Young Adult | Fructose - pharmacology | Irritable Bowel Syndrome - diagnostic imaging | Adult | Colon - physiopathology | Female | Hydrogen - analysis | Hydrogen - metabolism | Colon, Sigmoid - diagnostic imaging | Flatulence - etiology | Abdominal Pain - etiology | Double-Blind Method | Dietary Carbohydrates - pharmacology | Breath Tests | Glucose - pharmacology | Irritable Bowel Syndrome - physiopathology | Cross-Over Studies | Magnetic Resonance Imaging | Irritable Bowel Syndrome - complications | Glucose - metabolism | Diarrhea - etiology | Inulin - metabolism | Gastrointestinal Contents - drug effects | Gas industry | Gastrointestinal diseases | Natural gas | Irritable bowel syndrome | Index Medicus | Abridged Index Medicus
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6. Full Text Effect of changing the amount and type of fat and carbohydrate on insulin sensitivity and cardiovascular risk: The RISCK (Reading, Imperial, Surrey, Cambridge, and Kings) trial
by Jebb, Susan A and Lovegrove, Julie A and Griffin, Bruce A and Frost, Gary S and Moore, Carmel S and Chatfield, Mark D and Bluck, Les J and Williams, Christine M and Sanders, Thomas A.B and RISCK Study Grp and RISCK Study Group
American Journal of Clinical Nutrition, ISSN 0002-9165, 10/2010, Volume 92, Issue 4, pp. 748 - 758
Background: Insulin sensitivity (Si) is improved by weight loss and exercise, but the effects of the replacement of saturated fatty acids (SFAs) with... 
LIFE-STYLE INTERVENTION | GLYCEMIC INDEX | METABOLIC SYNDROME | FIBRINOLYTIC-ACTIVITY | NUTRITION & DIETETICS | SERUM-LIPIDS | METAANALYSIS | ACIDS | DISEASE | PREVENTION | FACTOR-VII | Glucose Tolerance Test | Insulin - physiology | Dietary Carbohydrates - pharmacology | Cholesterol - blood | Humans | Middle Aged | Risk Factors | Male | Apolipoproteins B - blood | Dietary Fats - pharmacology | England - epidemiology | Cardiovascular Diseases - epidemiology | Cholesterol, HDL - blood | Adult | Female | Aged | Research Design | Metabolic Syndrome - epidemiology | Apolipoprotein A-I - blood | Fatty Acids - pharmacology | Monounsaturated fatty acids | Low density lipoproteins | Research | Metabolic syndrome X | Cardiovascular diseases | Health aspects | Saturated fatty acids | Risk factors | Cardiovascular system | Carbohydrates | Oils & fats | Physiology | Insulin | Fatty acids | Index Medicus | Abridged Index Medicus
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7. Full Text Shifts in the rumen microbiota due to the type of carbohydrate and level of protein ingested by dairy cattle are associated with changes in rumen fermentation
by Belanche, Alejandro and Doreau, Michel and Edwards, Joan E and Moorby, Jon M and Pinloche, Eric and Newbold, Charles J
Journal of Nutrition, ISSN 0022-3166, 09/2012, Volume 142, Issue 9, pp. 1684 - 1692
Balancing energy and nitrogen in the rumen is a key to both profitability and environmental sustainability. Four dairy cows were used in a Latin square... 
DIGESTION | RUMINANTS | BACTERIA | NUTRITION & DIETETICS | AMMONIA | BOVINE RUMEN | FREQUENCY | DYNAMICS | ACIDOSIS | COLONIZATION | ANAEROBIC FUNGI | Genes, Bacterial | Dietary Carbohydrates - pharmacology | Adaptation, Physiological - physiology | Animal Nutritional Physiological Phenomena - physiology | Circadian Rhythm - physiology | Dietary Carbohydrates - metabolism | Dietary Proteins - metabolism | Metagenome - genetics | Animals | Rumen - metabolism | Polymorphism, Restriction Fragment Length | Animal Feed - microbiology | Fermentation - physiology | Models, Biological | Dietary Proteins - pharmacology | Dairying | Neocallimastigales - genetics | Nitrogen - pharmacology | Female | Rumen - microbiology | Cattle - physiology | Research | Rumination | Food and nutrition | Rumen fermentation | Dairy cattle | Index Medicus
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8. Full Text Acyl and Total Ghrelin Are Suppressed Strongly by Ingested Proteins, Weakly by Lipids, and Biphasically by Carbohydrates
by Foster-Schubert, Karen E and Overduin, Joost and Prudom, Catherine E and Liu, Jianhua and Callahan, Holly S and Gaylinn, Bruce D and Thorner, Michael O and Cummings, David E
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2008, Volume 93, Issue 5, pp. 1971 - 1979
Context: Ghrelin is an orexigenic hormone that can increase body weight. Its circulating levels increase before meals and are suppressed after food ingestion.... 
ENERGY-BALANCE | HIGH-FAT | POSTPRANDIAL SUPPRESSION | RESPONSES | TEST MEALS | PLASMA-INSULIN | FOOD-INTAKE | ENDOCRINOLOGY & METABOLISM | BODY-WEIGHT REGULATION | APPETITE | OBESE WOMEN | Appetite | Area Under Curve | Dietary Carbohydrates - pharmacology | Humans | Middle Aged | Male | Insulin - blood | Cross-Over Studies | Ghrelin - blood | Leptin - blood | Time Factors | Dietary Fats - pharmacology | Dietary Proteins - pharmacology | Adult | Female | Aged | Acylation | Index Medicus | Abridged Index Medicus | Original
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9. Full Text Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men
by Hall, Kevin D and Chen, Kong Y and Guo, Juen and Lam, Yan Y and Leibel, Rudolph L and Mayer, Laurel E. S and Reitman, Marc L and Rosenbaum, Michael and Smith, Steven R and Walsh, B. Timothy and Ravussin, Eric
American Journal of Clinical Nutrition, ISSN 0002-9165, 08/2016, Volume 104, Issue 2, pp. 324 - 333
Background: The carbohydrate-insulin model of obesity posits that habitual consumption of a high-carbohydrate diet sequesters fat within adipose tissue because... 
Macronutrients | Energy expenditure | Fat | Carbohydrate | Insulin | Body composition | Ketogenic diet | insulin | HIGH-FAT DIET | METABOLIC ADAPTATION | HUMANS | RANDOMIZED CONTROLLED-TRIAL | energy expenditure | carbohydrate | BALANCE | body composition | NUTRITION & DIETETICS | ketogenic diet | CALORIC RESTRICTION | fat | HIGH-PROTEIN | macronutrients | WEIGHT-GAIN | ADIPOSE-TISSUE | Dietary Carbohydrates - administration & dosage | Obesity - diet therapy | Dietary Fats - metabolism | Diet, Ketogenic | Dietary Carbohydrates - pharmacology | Humans | Male | Dietary Carbohydrates - metabolism | Energy Intake | Obesity - metabolism | Overweight | Adipose Tissue - metabolism | Body Composition - drug effects | Dietary Fats - pharmacology | Weight Loss | Dietary Fats - administration & dosage | Adult | Diet, Carbohydrate-Restricted | Energy Metabolism - drug effects | Obesity | Fat metabolism | Diet therapy | Physiological aspects | Research | Health aspects | Energy | Human body | Diet | Men | Oils & fats | Oxidation | Index Medicus | Abridged Index Medicus
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10. Full Text Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota
by Purna C. Kashyap and Angela Marcobal and Luke K. Ursell and Samuel A. Smits and Erica D. Sonnenburg and Elizabeth K. Costello and Steven K. Higginbottom and Steven E. Domino and Susan P. Holmes and David A. Relman and Rob Knight and Jeffrey I. Gordon and Justin L. Sonnenburg
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 42, pp. 17059 - 17064
We investigate how host mucus glycan composition interacts with dietary carbohydrate content to influence the composition and expressed functions of a human... 
Polysaccharides | Microbiota | Gnotobiotics | Diet | Metabolites | Communities | Mucins | Mucus | Mice | Genotypes | Metabolomics | Intestinal microbiota | Host-microbial mutualism | BACTERIAL SYMBIONT | MULTIDISCIPLINARY SCIENCES | FUT2 | host-microbial mutualism | MUCOSA | intestinal microbiota | INFLAMMATORY-BOWEL-DISEASE | metabolomics | INFECTION | MICE | FUCOSYLATION | ECOSYSTEM | ASSOCIATION | SECRETOR STATUS | Fucosyltransferases - genetics | Intestinal Mucosa - metabolism | Microbiota - physiology | Dietary Carbohydrates - pharmacology | Humans | Glucans - genetics | Intestinal Mucosa - microbiology | Mice, Knockout | Bacteroides - genetics | Bacteroides - metabolism | Fucosyltransferases - metabolism | Animals | Glucans - metabolism | Host-parasite relationships | Physiological aspects | Carbohydrate metabolism | Genetic aspects | Research | Gene expression | Microbial colonies | Health aspects | Carbohydrates | Genotype & phenotype | Gram-negative bacteria | Rodents | Index Medicus | Biological Sciences | host–microbial mutualism
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11. Full Text Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
by Mensink, R.P and Zock, P.L and Kester, A.D.M and Katan, M.B
American Journal of Clinical Nutrition, ISSN 0002-9165, 01/2003, Volume 77, Issue 5, pp. 1146 - 1155
Background: The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their effects on LDL cholesterol.... 
Carbohydrates | Serum lipoproteins | Diet | Fatty acids | Coronary artery disease risk | carbohydrates | SUNFLOWER OIL | fatty acids | PALMITIC ACID | DENSITY-LIPOPROTEIN-CHOLESTEROL | CORONARY HEART-DISEASE | TRANS-FATTY | HEALTHY-YOUNG MEN | NUTRITION & DIETETICS | PLASMA-LIPIDS | HYDROGENATED SOYBEAN OIL | STEARIC-ACID | coronary artery disease risk | diet | NORMOLIPIDEMIC MEN | serum lipoproteins | Dietary Carbohydrates - administration & dosage | Cardiovascular Diseases - etiology | Fatty Acids - chemistry | Cholesterol, HDL - drug effects | Dietary Carbohydrates - pharmacology | Cholesterol - blood | Humans | Risk Factors | Fatty Acids, Unsaturated - pharmacology | Male | Biomarkers - blood | Lipoproteins - blood | Isomerism | Cardiovascular Diseases - blood | Cholesterol, HDL - blood | Fatty Acids - administration & dosage | Adult | Female | Fatty Acids - pharmacology | Fatty Acids, Unsaturated - administration & dosage | Nutrition | Dietary supplements | Dietary fat | Research | Coronary heart disease | Absorption (Physiology) | Cholesterol | Prevention | Proteolipids | Lipoproteins | Risk factors (Health) | Analysis | Physiological aspects | Causes of | Serum | Health aspects | Index Medicus | Abridged Index Medicus | hydrogenated soybean oil | density-lipoprotein-cholesterol | sunflower oil | coronary heart-disease | stearic-acid | healthy-young men | palmitic acid | plasma-lipids | trans-fatty | normolipidemic men
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