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Journal Article
Journal Article
Journal Article
Journal of carcinogenesis, ISSN 1477-3163, 2012, Volume 11, Issue 1, pp. 2 - 2
Since their first discovery as potential anti-cancer drugs decades ago, there is increasing evidence that digitalis-like compounds (DLC) have anti-tumor... 
Adrenal exhaustion | stress | endogenous digitalis-like compounds | Na/K-ATPase | isoforms | threshold | tumorigenesis
Journal Article
Journal Article
JOURNAL OF PSYCHIATRIC RESEARCH, ISSN 0022-3956, 08/2019, Volume 115, pp. 21 - 28
Na+, K+-ATPase is an essential membrane transporter. In the brain, the alpha 3 isoform of Na+, K+-ATPase is vital for neuronal function. The enzyme and its... 
DIGITALIS-LIKE COMPOUNDS | SODIUM-PUMP | PSYCHIATRY | ENDOGENOUS CARDIAC STEROIDS | SCHIZOPHRENIA | BIPOLAR DISORDER | RAPID-ONSET | EXPRESSION | BRAIN | INTERNEURONS | PATHOPHYSIOLOGY
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 08/2007, Volume 293, Issue 2, pp. 509 - 536
Cardiotonic steroids (CTS), long used to treat heart failure, are endogenously produced in mammals. Among them are the hydrophilic cardenolide ouabain and the... 
Cell proliferation | Arterial hypertension | Endogenous cardiotonic steroids | Rostafuroxin | Sodium/potassium-adenosinetriphosphatase | Cancer therapy | Ouabain | Marinobufagenin | Sodium pump | Oleandrin | Bufalin | Sodium metabolism | ouabain | PROTEIN-KINASE-C | PHYSIOLOGY | BOVINE ADRENOCORTICAL-CELLS | BUFALIN INDUCES APOPTOSIS | PLASMALEMMAL NA/K-ATPASE | cell proliferation | SIGNAL-TRANSDUCING FUNCTION | endogenous cardiotonic steroids | FACTOR-KAPPA-B | oleandrin | sodium/potassium-adenosinetriphosphatase | VASCULAR SMOOTH-MUSCLE | NA+-K+-ATPASE | CELL BIOLOGY | arterial hypertension | cancer therapy | OUABAIN-LIKE COMPOUND | sodium pump | DIGITALIS-LIKE COMPOUNDS | bufalin | rostafuroxin | sodium metabolism | marinobufagenin | Cardiac Glycosides - pharmacology | Neoplasms - metabolism | Antihypertensive Agents - pharmacology | Digoxin - metabolism | Calcium - metabolism | Humans | Myocardial Contraction - drug effects | Hypertension - drug therapy | Antineoplastic Agents - therapeutic use | Structure-Activity Relationship | Antihypertensive Agents - metabolism | Ouabain - metabolism | Antineoplastic Agents - metabolism | Bufanolides - metabolism | Antineoplastic Agents - pharmacology | Blood Pressure - drug effects | Molecular Structure | Cell Death - drug effects | Sodium Chloride - metabolism | Ouabain - pharmacology | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Diabetes Mellitus - metabolism | Cardiovascular System - drug effects | Antihypertensive Agents - therapeutic use | Antineoplastic Agents - chemistry | Digoxin - pharmacology | Hypertension - physiopathology | Hypertension - metabolism | Neoplasms - drug therapy | Antihypertensive Agents - chemistry | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Myocytes, Cardiac - drug effects | Cardiovascular System - metabolism | Diabetes Mellitus - physiopathology | Cardiac Glycosides - chemistry | Myocytes, Cardiac - metabolism | Bufanolides - pharmacology | Cardiac Glycosides - metabolism | Cardiac Glycosides - therapeutic use | Cell Proliferation - drug effects | Neoplasms - pathology
Journal Article