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excitatory amino acid antagonists - pharmacology (37) 37
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membrane potentials - drug effects (34) 34
neurons - physiology (34) 34
analysis of variance (33) 33
nicotinic receptors (33) 33
time factors (33) 33
alkaloids - pharmacology (31) 31
dopamine - metabolism (31) 31
action potentials - drug effects (30) 30
central-nervous-system (30) 30
pyridines - pharmacology (30) 30
behavior, animal - drug effects (29) 29
acetylcholine - metabolism (28) 28
nicotine - administration & dosage (28) 28
nucleus-accumbens (28) 28
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nervous system (26) 26
animals, newborn (25) 25
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neurons - metabolism (25) 25
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Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15148 - 15157
Several behavioral effects of nicotine are mediated by changes in serotonin (5-HT) release in brain areas that receive serotonergic afferents from the dorsal... 
Electric Stimulation | Rats, Wistar | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotinic Antagonists - pharmacology | Raphe Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Nicotine - pharmacology | Excitatory Postsynaptic Potentials - physiology | Muscarinic Antagonists - pharmacology | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Cadmium Chloride - pharmacology | Cholinergic Agonists - pharmacology | Ryanodine - pharmacology | Animals, Newborn | Serotonergic Neurons - physiology | Presynaptic Terminals - drug effects | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Glutamic Acid - physiology | Rats | Atropine - pharmacology | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Chelating Agents - pharmacology | Aconitine - pharmacology | GABA Antagonists - pharmacology | Physostigmine - pharmacology | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Receptors, Nicotinic - physiology | Nicotine - analogs & derivatives | Serotonin - metabolism | In Vitro Techniques | Serotonergic Neurons - cytology | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 5/2014, Volume 231, Issue 9, pp. 1975 - 1985
Neuronal nicotinic acetylcholine receptors (nAChRs) play a modulatory role in cognition, and zebrafish provide a preclinical model to study learning and... 
Neurosciences | α-Conotoxin | Scopolamine | Neuronal nicotinic receptors | Zebrafish | Cholinergic system | Methyllycaconitine | Mecamylamine | Biomedicine | Dihydro-β-erythroidine | Pharmacology/Toxicology | T-maze | Psychiatry | Spatial memory | Dihydro-beta-erythroidine | DANIO-RERIO | TASK | CHOLINERGIC CHANNEL ACTIVATOR | PSYCHIATRY | BEHAVIOR | INVOLVEMENT | Spatialmemory | SYNAPTIC PLASTICITY | NEUROSCIENCES | COGNITIVE FUNCTION | SELECTIVE STIMULATION | PARTIAL AGONIST | PHARMACOLOGY & PHARMACY | alpha-Conotoxin | WORKING-MEMORY | Memory - drug effects | Cholinergic Agents - pharmacology | Dihydro-beta-Erythroidine - pharmacology | Nicotinic Antagonists - pharmacology | Nicotine - pharmacology | Dose-Response Relationship, Drug | Scopolamine Hydrobromide - pharmacology | Muscarinic Antagonists - pharmacology | Mecamylamine - pharmacology | Neurons - physiology | Swimming | Neurons - drug effects | Nicotinic Agonists - pharmacology | Azocines - chemistry | Receptors, Nicotinic - metabolism | Alkaloids - pharmacology | Maze Learning - physiology | Zebrafish Proteins - metabolism | Quinolizines - pharmacology | Aconitine - analogs & derivatives | Aconitine - pharmacology | Maze Learning - drug effects | Conotoxins - pharmacology | Animals | Nicotinic Antagonists - chemistry | Zebrafish - physiology | Azocines - pharmacology | Alkaloids - chemistry | Quinolizines - chemistry | Memory - physiology | Learning | Receptors | Memory | Zebra fish | Physiological aspects | Genetic aspects | Acetylcholine | Research | Fish | Psychopharmacology | Animal memory | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2008, Volume 28, Issue 14, pp. 3769 - 3780
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 807 - 816
Accumulating evidence suggests that acetylcholine nicotinic systems may contribute importantly to the abuse-related effects of d-methamphetamine (d-MA). The... 
DIHYDRO-BETA-ERYTHROIDINE | ACETYLCHOLINE-RECEPTORS | SQUIRREL-MONKEYS | DOPAMINE RELEASE | BEHAVIORAL SENSITIZATION | PHARMACOLOGY & PHARMACY | MONOAMINE TRANSPORTERS | STIMULUS PROPERTIES | ALPHA-BUNGAROTOXIN | NUCLEUS-ACCUMBENS | UPTAKE INHIBITORS | Nicotinic Antagonists - administration & dosage | Cholinergic Agents - administration & dosage | Cholinergic Agents - pharmacology | Varenicline | Pentobarbital - administration & dosage | Pentobarbital - pharmacology | Male | Nicotinic Antagonists - pharmacology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Drug Interactions | Muscarinic Antagonists - pharmacology | Discrimination (Psychology) | Mecamylamine - pharmacology | Behavior, Animal - drug effects | Nicotinic Agonists - pharmacology | Discrimination Learning | Methamphetamine - pharmacology | Dopamine Agonists - pharmacology | Mecamylamine - administration & dosage | Dextroamphetamine - pharmacology | Quinoxalines - administration & dosage | Reinforcement (Psychology) | Rats | Benzazepines - pharmacology | Rats, Sprague-Dawley | Muscarinic Antagonists - administration & dosage | Nicotinic Agonists - administration & dosage | Animals | Cholinesterase Inhibitors - administration & dosage | Cholinesterase Inhibitors - pharmacology | Methamphetamine - administration & dosage | Dopamine Agonists - administration & dosage | Conditioning, Operant | Benzazepines - administration & dosage | Dextroamphetamine - administration & dosage | Index Medicus | Behavioral Pharmacology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2011, Volume 31, Issue 7, pp. 2537 - 2548
Journal Article
Psychopharmacology, ISSN 0033-3158, 7/2013, Volume 228, Issue 2, pp. 321 - 333
Receptor mechanisms underlying the behavioral effects of clinically used nicotinic acetylcholine receptor agonists have not been fully established.Drug... 
Drug discrimination | Neurosciences | Agonist | Varenicline | Cytisine | Efficacy | Mecamylamine | Biomedicine | Mouse | Antagonist | Dihydro-β-erythroidine | Pharmacology/Toxicology | Psychiatry | Nicotine | Dihydro-beta-erythroidine | PSYCHIATRY | PHARMACOLOGICAL CHARACTERIZATION | RATS | RECEPTOR PARTIAL AGONIST | NEUROSCIENCES | ACETYLCHOLINE-RECEPTORS | MU OPIOIDS | PHARMACOLOGY & PHARMACY | DISCRIMINATIVE STIMULUS PROPERTIES | ALPHA-4-BETA-2 | Nicotine - administration & dosage | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotine - pharmacology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Discrimination Learning - drug effects | Tobacco Use Cessation Products | Mecamylamine - pharmacology | Nicotinic Agonists - pharmacology | Quinolizines - administration & dosage | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Alkaloids - pharmacology | Morphine - pharmacology | Quinoxalines - administration & dosage | Mice, Inbred C57BL | Quinolizines - pharmacology | Benzazepines - pharmacology | Smoking Cessation - methods | Nicotinic Agonists - administration & dosage | Animals | Alkaloids - administration & dosage | Azocines - pharmacology | Benzazepines - administration & dosage | Mice | Azocines - administration & dosage | Midazolam - pharmacology | Smoking cessation programs | Dosage and administration | Health aspects | Smoking cessation | Pharmacology | Rodents | Index Medicus | dihydro-β-erythroidine | mecamylamine | varenicline | mouse | nicotine | drug discrimination | agonist | antagonist | cytisine | efficacy
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/1997, Volume 17, Issue 2, pp. 576 - 585
Presynaptic nicotinic acetylcholine receptors (nAChRs) are present in many regions of the brain and potentially serve as targets for the pharmacological action... 
GABA | calcium | facilitation | thalamus (sensory nuclei) | nicotinic acetylcholine receptors | presynaptic | ADRENAL CHROMAFFIN CELLS | INTERPEDUNCULAR NUCLEUS | FROG NEUROMUSCULAR-JUNCTION | OPTIC-NERVE TERMINALS | RAT CENTRAL NEURONS | NEUROSCIENCES | LATERAL GENICULATE-NUCLEUS | ACETYLCHOLINE-RECEPTORS | SUBUNIT MESSENGER-RNAS | CHOLINERGIC RECEPTORS | EXCITATORY SYNAPTIC TRANSMISSION | Thalamic Nuclei - metabolism | Dihydro-beta-Erythroidine - pharmacology | Lobeline - pharmacology | Nicotinic Antagonists - pharmacology | Pyridazines - pharmacology | Cations, Divalent - pharmacology | Nicotine - pharmacology | Quinolizines | Calcium Channels - physiology | Calcium - physiology | Receptors, Nicotinic - chemistry | Receptors, GABA-A - drug effects | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Dimethylphenylpiperazinium Iodide - pharmacology | Ion Transport | gamma-Aminobutyric Acid - secretion | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Microcystins | Alkaloids - pharmacology | Mice, Inbred C57BL | Atropine - pharmacology | Aconitine - analogs & derivatives | Marine Toxins - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Neurons, Afferent - physiology | GABA Antagonists - pharmacology | Mice, Knockout | Carbachol - pharmacology | Arousal - physiology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Patch-Clamp Techniques | Animals | Azocines | Receptors, Nicotinic - physiology | Bacterial Toxins - pharmacology | Thalamic Nuclei - secretion | Mice | Pyridines - pharmacology | Receptors, Nicotinic - genetics | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 540, Issue 1, pp. 96 - 106
Male Wistar rats were trained to discriminate (−)-nicotine (0.4 mg/kg) from saline under a two-lever, fixed-ratio 10 schedule of water reinforcement. During... 
Drug discrimination | Rat | Nicotinic acetylcholine receptor | Cannabinoid system | Nicotine | nicotine | DIHYDRO-BETA-ERYTHROIDINE | rat | ANTAGONIST SR141716A | BEHAVIOR | PLACE PREFERENCES | ANANDAMIDE TRANSPORT | drug discrimination | AFFINITY | PHARMACOLOGY & PHARMACY | cannabinoid system | MEDIATED RESPONSES | XENOPUS OOCYTES | BRAIN | nicotinic acetylcholine receptor | AGONIST | Receptor, Cannabinoid, CB2 - physiology | Rats, Wistar | Cannabinoid Receptor Antagonists | Dihydro-beta-Erythroidine - pharmacology | Bornanes - pharmacology | Receptors, Cannabinoid - physiology | Male | Nicotinic Antagonists - pharmacology | Azetidines - pharmacology | Benzoxazines | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Receptor, Cannabinoid, CB1 - physiology | Nicotine - pharmacology | Dose-Response Relationship, Drug | Discrimination Learning - drug effects | Mecamylamine - pharmacology | Benzamides - pharmacology | Cyclohexanols - pharmacology | Endocannabinoids | Nicotinic Agonists - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Morpholines - pharmacology | Rats | Aconitine - analogs & derivatives | Aconitine - pharmacology | Arachidonic Acids - pharmacology | Discrimination Learning - physiology | Naphthalenes - pharmacology | Drug Synergism | Animals | Receptors, Nicotinic - physiology | Polyunsaturated Alkamides - pharmacology | Pyridines - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Enzymes | Pyridine | Hydrolases | Drug therapy, Combination | Cyclohexanol | Fatty acids | Index Medicus
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 01/2009, Volume 587, Issue 2, pp. 345 - 361
Journal Article