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Best Practice and Research: Clinical Endocrinology and Metabolism, 08/2011, Volume 25, Issue 4, pp. 543 - 559
The conformationally flexible secosteroid, 1α,25(OH) vitamin D (1α,25(OH) D ) initiates biological responses via binding to the vitamin D receptor (VDR). The... 
retinoid X receptor | genomic responses | rapid responses | transcription | corepressor | ligand conformation | 1α,25-dihydroxyvitamin D | vitamin D receptor | vitamin D responsive elements | coactivator
Journal Article
Calcified Tissue International, ISSN 0171-967X, 2/2013, Volume 92, Issue 2, pp. 77 - 98
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 01/2018, Volume 175, pp. 23 - 28
Vitamin D has emerged as a key regulator of innate immune responses to pathogen threat. The hormonal form of vitamin D signals through a nuclear receptor... 
Vitamin D deficiency | Intervention trials | Vitamin D receptor | 1α,25-dihydroxyvitamin D | Innate immunity | Crohn's disease | Autophagy | REDUCED RISK | VARIANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUSCEPTIBILITY LOCI | NOD2 | INFLAMMATORY-BOWEL-DISEASE | GENE | ENDOCRINOLOGY & METABOLISM | D-RECEPTOR | EPIDEMIOLOGY | 1 alpha,25-dihydroxyvitamin D-3 | GENOME-WIDE ASSOCIATION | Crohn Disease - genetics | Vitamin D Deficiency - complications | Humans | Vitamin D Response Element - immunology | Nod2 Signaling Adaptor Protein - genetics | Interleukin-1beta - genetics | Vitamin D Response Element - genetics | Receptors, Calcitriol - genetics | Crohn Disease - complications | Vitamin D - immunology | Transcription, Genetic | Vitamin D Deficiency - immunology | Vitamin D Deficiency - genetics | Immunity, Innate - drug effects | Signal Transduction | Gene Expression Regulation | Interleukin-1beta - immunology | Nod2 Signaling Adaptor Protein - immunology | Clinical Trials as Topic | Crohn Disease - diet therapy | Crohn Disease - immunology | Receptors, Calcitriol - immunology | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Vitamin D Deficiency - diet therapy | Vitamin D - therapeutic use | Dietary Supplements | Medical research | Immune response | Vitamin D | Gastrointestinal diseases | Medicine, Experimental | Calcifediol | Disease susceptibility | Genetic transcription | Alfacalcidol
Journal Article
Joint Bone Spine, ISSN 1297-319X, 2010, Volume 77, Issue 6, pp. 552 - 557
Abstract Calcitriol, or 1,25-dihydroxyvitamin D3 (1,25(OH)2 D3) is a well-known endocrine regulator of calcium homeostasis. More recently, local calcitriol... 
Internal Medicine | Rheumatology | Dendritic cell | B cell | 1α-hydroxylase | Vitamin D receptor | T cell | 1,25 dihydroxyvitamin D3 | 25-hydroxylase | Macrophage | RHEUMATOID-ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | D DEFICIENCY | RHEUMATOLOGY | 1-ALPHA,25-DIHYDROXYVITAMIN D-3 | DISEASE-ACTIVITY | IN-VITRO | IMMUNE-SYSTEM | 1 alpha-hydroxylase | REGULATORY T-CELLS | 1,25-DIHYDROXYVITAMIN D-3 | D-RECEPTOR | Calcium - metabolism | Dendritic Cells - immunology | Humans | Vitamin D - immunology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Immune System - immunology | Dendritic Cells - drug effects | B-Lymphocytes - metabolism | Calcium Signaling | Dendritic Cells - metabolism | Macrophages - immunology | Disease Models, Animal | Cell Survival - drug effects | Cells, Cultured | Vitamin D - pharmacology | Inflammation - immunology | Immunomodulation - physiology | B-Lymphocytes - drug effects | Macrophages - metabolism | Animals | B-Lymphocytes - immunology | Homeostasis - physiology | Macrophages - drug effects | T-Lymphocytes - immunology | Vitamin D - metabolism | Enzymes | Rheumatoid factor | Vitamin D | Dendritic cells | Type 1 diabetes | Analysis | Rheumatoid arthritis | Calcifediol | Alfacalcidol | T cells | Macrophages | Public health | Cell culture | Vitamin D3 | Animal models | Spine | Calcitriol | Helper cells | Lymphocytes T | Joint diseases | Graft rejection | Infection | Antigen-presenting cells | Supplementation | Vitamin D receptors | Cardiovascular diseases | Calcium homeostasis
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e30773
Vitamin D binding protein (DBP) plays a key role in the bioavailability of active 1,25-dihydroxyvitamin D (1,25(OH)(2)D) and its precursor 25-hydroxyvitamin D... 
ACTIVATION | METABOLISM | MITOCHONDRIAL | MULTIDISCIPLINARY SCIENCES | HUMAN MAMMARY CELLS | SERUM | D-RECEPTOR | LIGAND | D-3 | EXPRESSION | GENOME-WIDE ASSOCIATION | Models, Theoretical | Vitamin D-Binding Protein - metabolism | Humans | Receptors, Calcitriol - physiology | Cells, Cultured | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Vitamin D - pharmacology | Genotype | Monocytes - metabolism | Receptors, Calcitriol - metabolism | Receptors, Calcitriol - genetics | Vitamin D-Binding Protein - blood | Monocytes - drug effects | Osmolar Concentration | Vitamin D-Binding Protein - genetics | Models, Biological | Vitamin D-Binding Protein - physiology | Protein Binding | Ligands | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Vitamin D - pharmacokinetics | Vitamin D Response Element | Vitamin D | Analysis | Cytochrome P-450 | Calcifediol | Genetic aspects | Alfacalcidol | Protein binding | Two dimensional models | Proteins | Mitochondria | Metabolites | Mathematical analysis | Surgery | Fibroblasts | Mathematical models | Supplementation | 25-Hydroxyvitamin D | Binding | Dendritic cells | Dihydroxyvitamin D | Bioavailability | Metabolism | Biological activity | Serum levels | Studies | Monocytes | Hospitals | Affinity | In vivo methods and tests | Vitamin D receptors | Molecular biology | Steady state models
Journal Article
ENDOCRINOLOGY, ISSN 0013-7227, 11/2017, Volume 158, Issue 11, pp. 3792 - 3804
Journal Article
European Journal of Nutrition, ISSN 1436-6207, 4/2018, Volume 57, Issue 3, pp. 1059 - 1072
Journal Article