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Pharmacology and Therapeutics, ISSN 0163-7258, 06/2016, Volume 162, pp. 1 - 9
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2012, Volume 55, Issue 21, pp. 9312 - 9330
DYRKs (dual specificity, tyrosine phosphorylation regulated kinases) and CLKs (cdc2-like kinases) are implicated in the onset and development of Alzheimer’s... 
TAU EXON 10 | FUNCTIONAL-LINK | CHEMISTRY, MEDICINAL | DYRK1A OVEREXPRESSION | DOWN-SYNDROME | INTRACELLULAR TARGETS | NEUROFIBRILLARY DEGENERATION | DUAL-SPECIFICITY | PHOSPHATIDYLINOSITOL 3,5-BISPHOSPHATE | AFFINITY-CHROMATOGRAPHY | GLYCOGEN-SYNTHASE KINASE | Stereoisomerism | Humans | Imidazoles - chemistry | Alkaloids - chemical synthesis | Crystallography, X-Ray | Structure-Activity Relationship | Dioxoles - chemical synthesis | Protein Kinase Inhibitors - chemistry | Neuroprotective Agents - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Protein-Tyrosine Kinases - chemistry | Dioxoles - pharmacology | Molecular Structure | Pyramidal Cells - drug effects | Cell Death - drug effects | Imidazoles - chemical synthesis | Porifera - chemistry | Pyramidal Cells - cytology | Cell Line | Protein Kinase Inhibitors - chemical synthesis | Brain - cytology | Recombinant Proteins - antagonists & inhibitors | Alkaloids - pharmacology | Neuroprotective Agents - chemistry | Glutamic Acid - pharmacology | Models, Molecular | Rats | Recombinant Proteins - chemistry | Cyclin-Dependent Kinase 2 - chemistry | Imidazoles - pharmacology | Dioxoles - chemistry | Rats, Sprague-Dawley | Brain - drug effects | Neuroprotective Agents - chemical synthesis | Amyloid beta-Protein Precursor - genetics | Animals | Chromatography, Affinity | Cyclin-Dependent Kinase 2 - antagonists & inhibitors | Protein Binding | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - chemistry | In Vitro Techniques | Alkaloids - chemistry | Protein-Tyrosine Kinases - antagonists & inhibitors | Organic chemistry | Chemical Sciences
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 03/2015, Volume 80, Issue 6, pp. 3339 - 3342
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2002, Volume 124, Issue 23, pp. 6552 - 6554
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2017, Volume 139, pp. 441 - 453
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2017, Volume 27, Issue 2, pp. 176 - 179
[Display omitted] (−)-Cubebin (CUB), isolated from seeds of Piper cubeba, was used as starting material to obtain the derivatives (−)-hinokinin (HK) and... 
Anti-inflammatory activity | (−)-Hinokinin | Piper cubeba | (−)-Cubebin | (−)-O-benzylcubebin | SWISS-MODEL | DENSITY | CHEMISTRY, MEDICINAL | APPROXIMATION | (-)-Cubebin | (-)-0-benzylcubebin | LEAVES | CHEMISTRY, ORGANIC | (-)-Hinokinin | LIGNANS | Rats, Wistar | Furans - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Benzodioxoles - administration & dosage | Cyclooxygenase 2 Inhibitors - chemistry | Dioxoles - chemical synthesis | Lignans - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Cyproheptadine - pharmacology | Polysorbates - pharmacology | Dextrans - pharmacology | Dioxoles - administration & dosage | Furans - chemistry | Computer Simulation | Dioxoles - pharmacology | 4-Butyrolactone - chemistry | Benzodioxoles - chemistry | Lignans - chemical synthesis | Rutaceae - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Benzodioxoles - chemical synthesis | Cyclooxygenase 2 Inhibitors - chemical synthesis | Dinoprostone - pharmacology | Catalytic Domain | Cyclooxygenase 2 Inhibitors - pharmacology | Lignans - chemistry | Cyclooxygenase 2 - chemistry | Cyclooxygenase 2 Inhibitors - administration & dosage | 4-Butyrolactone - pharmacology | 4-Butyrolactone - chemical synthesis | Dioxoles - chemistry | Indomethacin - pharmacology | Lignans - isolation & purification | Lignans - administration & dosage | Animals | 4-Butyrolactone - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Ligands | Mice | Molecular Docking Simulation | 4-Butyrolactone - analogs & derivatives | Edema - chemically induced | Furans - chemical synthesis | Benzodioxoles - pharmacology | Furans - administration & dosage
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 04/2013, Volume 62, pp. 728 - 737
Journal Article
Organic Letters, ISSN 1523-7060, 03/2015, Volume 17, Issue 5, pp. 1232 - 1235
Journal Article
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