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1. Full Text Functional analysis of active amino acid residues of the mercaptosuccinate dioxygenase of Variovorax paradoxus B4
by Brandt, Ulrike and Galant, Gulsina and Meinert-Berning, Christina and Steinbüchel, Alexander
Enzyme and microbial technology, ISSN 0141-0229, 01/2019, Volume 120, pp. 61 - 68
Thiol dioxygenase | Active site structure | Site-directed mutagenesis | Mercaptosuccinate dioxygenase | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Amino Acid Sequence | Catalytic Domain | Dioxygenases - metabolism | Comamonadaceae - enzymology | Dioxygenases - chemistry | Mutagenesis, Site-Directed | Amino Acids - chemistry | Substrate Specificity | Cysteine Dioxygenase - chemistry | Cysteine Dioxygenase - metabolism | Amino Acids - genetics | Sequence Homology | Dioxygenases - genetics | Thiomalates - metabolism | Catalysis | Mutation | Cysteine Dioxygenase - genetics | Enzymes | Sulfites | Cysteine | Thiols | Analysis | Heme | Iron proteins | Cystine | Index Medicus
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2. Full Text QM/MM-Simulationen ergeben synergetische Substrat- und Sauerstoffaktivierung in Salicylat-Dioxygenase
by Subhendu Roy and Johannes Kastner
Angewandte Chemie, ISSN 0044-8249, 01/2016, Volume 128, Issue 3, p. 1182
Dioxygenase
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3. Full Text Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
by Xu, Wei and Yang, Hui and Liu, Ying and Yang, Ying and Wang, Ping and Kim, Se-Hee and Ito, Shinsuke and Yang, Chen and Wang, Pu and Xiao, Meng-Tao and Liu, Li-xia and Jiang, Wen-qing and Liu, Jing and Zhang, Jin-ye and Wang, Bin and Frye, Stephen and Zhang, Yi and Xu, Yan-hui and Lei, Qun-ying and Guan, Kun-Liang and Zhao, Shi-min and Xiong, Yue
Cancer cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism | Index Medicus
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4. Full Text Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis
by Takeda, Yukiji and Costa, Sandra and Delamarre, Estelle and Roncal, Carmen and Leite De Oliveira, Rodrigo and Squadrito, Mario Leonardo and Finisguerra, Veronica and Deschoemaeker, Sofie and Bruyère, Françoise and Wenes, Mathias and Hamm, Alexander and Serneels, Jens and Magat, Julie and Bhattacharyya, Tapan and Anisimov, Andrey and Jordan, Benedicte F and Alitalo, Kari and Maxwell, Patrick and Gallez, Bernard and Zhuang, Zhen W and Saito, Yoshihiko and Simons, Michael and De Palma, Michele and Mazzone, Massimiliano
Nature (London), ISSN 0028-0836, 11/2011, Volume 479, Issue 7371, pp. 122 - 126
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Biological and medical sciences | Vertebrata | Animals | Genetics of eukaryotes. Biological and molecular evolution | Homeostasis | Extremities - pathology | Male | NF-kappa B - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases | Mice, 129 Strain | Ischemia - prevention & control | Necrosis | Procollagen-Proline Dioxygenase - metabolism | Arteries - growth & development | Macrophages - metabolism | Phenotype | Extremities - blood supply | Procollagen-Proline Dioxygenase - deficiency | Procollagen-Proline Dioxygenase - genetics | Alleles | Female | Heterozygote | Mice | Mice, Inbred BALB C | Myocytes, Smooth Muscle - cytology | Ischemia - pathology | Disease Models, Animal | Prevention | Care and treatment | Ischemia | Physiological aspects | Diagnosis | Research | Neovascularization | Macrophages | Oxidative stress | Angiogenesis | Genotype & phenotype | Wound healing | Medical imaging | Rodents | Veins & arteries | Index Medicus
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5. Full Text JunD Reduces Tumor Angiogenesis by Protecting Cells from Oxidative Stress
by Gerald, Damien and Berra, Edurne and Frapart, Yves M and Chan, Denise A and Giaccia, Amato J and Mansuy, Daniel and Pouysségur, Jacques and Yaniv, Moshe and Mechta-Grigoriou, Fatima
Cell (Cambridge), ISSN 0092-8674, 2004, Volume 118, Issue 6, pp. 781 - 794
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Proto-Oncogene Proteins c-jun - physiology | Reactive Oxygen Species - metabolism | Antioxidants - metabolism | Humans | ras Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit | Procollagen-Proline Dioxygenase - metabolism | Neoplasms - genetics | Neovascularization, Pathologic - physiopathology | Gene Expression Regulation, Neoplastic - genetics | Proto-Oncogene Proteins c-jun - genetics | Oxidative Stress - genetics | Neoplasms - blood supply | Up-Regulation - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | Dioxygenases | Iron - metabolism | Hydrogen Peroxide - metabolism | Transcription Factors - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Animals | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - metabolism | Oxidative stress | Genetic transcription | Research | Neovascularization | Index Medicus | Up-Regulation | Vascular Endothelial Growth Factor A | Reactive Oxygen Species | ras Proteins | Oxidative Stress | Hydrogen Peroxide | Biochemistry, Molecular Biology | Gene Expression Regulation, Neoplastic | Neovascularization, Pathologic | Iron | Neoplasms | Antioxidants | Life Sciences | Transcription Factors | Procollagen-Proline Dioxygenase | Proto-Oncogene Proteins c-jun | Cancer
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6. Full Text TET-mediated active DNA demethylation: Mechanism, function and beyond
by Wu, Xiaoji and Zhang, Yi
Nature reviews. Genetics, ISSN 1471-0056, 09/2017, Volume 18, Issue 9, pp. 517 - 534
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | DNA Methylation | Dioxygenases - metabolism | Animals | Dioxygenases - chemistry | Dioxygenases - genetics | 5-Methylcytosine - metabolism | Metabolic Networks and Pathways | Humans | Gene Expression Regulation | Genetic research | Cytosine | Research | Gene expression | Properties | Dioxygenase | Thymine | DNA glycosylase | Mapping | Base excision repair | Demethylation | Thymine DNA glycosylase | Dilution | Regulatory mechanisms (biology) | DNA methylation | Oxidation | Methylation | Dissection | Deoxyribonucleic acid--DNA | Index Medicus
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7. Full Text 4-Hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase: Exemplars of the α-keto acid dependent oxygenases
by Moran, Graham R
Archives of biochemistry and biophysics, ISSN 0003-9861, 02/2014, Volume 544, pp. 58 - 68
4-Hydroxyphenylpyruvate dioxygenase | Oxygenase | Dioxygenase | Molecular oxygen | Hydroxymandelate synthase | Ferrous | α-Keto acid | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | 4-Hydroxyphenylpyruvate Dioxygenase - antagonists & inhibitors | Dioxygenases - metabolism | Bacteria - chemistry | Dioxygenases - chemistry | 4-Hydroxyphenylpyruvate Dioxygenase - metabolism | Humans | Mandelic Acids - metabolism | Models, Molecular | Substrate Specificity | Mandelic Acids - chemistry | Animals | Bacteria - enzymology | Protein Conformation | 4-Hydroxyphenylpyruvate Dioxygenase - chemistry | Index Medicus
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