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Chemical Research in Toxicology, ISSN 0893-228X, 09/2008, Volume 21, Issue 9, pp. 1814 - 1822
In vitro covalent binding assessments of drugs have been useful in providing retrospective insights into the association between drug metabolism and a... 
ACYL GLUCURONIDES | CHEMISTRY, MEDICINAL | PROTEIN | RAT | REACTIVE METABOLITES | TIENILIC ACID | HEPATIC-NECROSIS | BIOACTIVATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | TOXICOLOGY | HUMAN URINE | Buspirone - chemistry | Raloxifene Hydrochloride - pharmacology | Thiazoles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Indomethacin - metabolism | Simvastatin - pharmacology | Diclofenac - chemistry | Thiazines - metabolism | Propranolol - pharmacology | Toxicity Tests - methods | Binding Sites | Simvastatin - metabolism | Microsomes, Liver - chemistry | Indomethacin - pharmacology | Paroxetine - metabolism | Raloxifene Hydrochloride - metabolism | Triazoles - metabolism | Ticrynafen - metabolism | Paroxetine - pharmacology | Diclofenac - metabolism | Paroxetine - chemistry | Diphenhydramine - pharmacology | Diclofenac - pharmacology | Triazoles - chemistry | Buspirone - metabolism | Ticrynafen - pharmacology | Structure-Activity Relationship | Buspirone - pharmacology | Hepatocytes - metabolism | Dose-Response Relationship, Drug | Carbamazepine - chemistry | Diphenhydramine - metabolism | Acetaminophen - pharmacology | Microsomes, Liver - drug effects | Propranolol - metabolism | Carbamazepine - metabolism | Thiazines - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Hepatocytes - drug effects | Carbamazepine - pharmacology | Simvastatin - chemistry | Acetaminophen - chemistry | Ticrynafen - chemistry | Propranolol - chemistry | Diphenhydramine - chemistry | Thiazines - chemistry | Triazoles - pharmacology | Indomethacin - chemistry | Thiazoles - chemistry | Thiazoles - pharmacology | Raloxifene Hydrochloride - chemistry | Index Medicus
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Journal Article
AAPS PharmSciTech, ISSN 1530-9932, 6/2012, Volume 13, Issue 2, pp. 556 - 567
We prepared pressure-sensitive adhesive (PSA) patches based on styrene–isoprene–styrene (SIS) thermoplastic elastomer using hot-melt coating method. The liquid... 
Biochemistry, general | Biotechnology | Biomedicine | rheology | Pharmacy | drug delivery | Pharmacology/Toxicology | thermoplastic elastomer | Peppas equation | MATRIX | DELIVERY-SYSTEMS | PRESSURE-SENSITIVE ADHESIVES | MODEL | SOLVENT | KINETICS | PHARMACOLOGY & PHARMACY | DIFFUSION | SIS | METHYL SALICYLATE | CAPSAICIN | Diphenhydramine - administration & dosage | Models, Chemical | Capsaicin - chemistry | Crystallography, X-Ray | Elastomers - chemistry | Administration, Cutaneous | Spectroscopy, Fourier Transform Infrared | Plasticizers - chemistry | Polystyrenes - chemistry | Capsaicin - administration & dosage | Drug Carriers | Salicylates - chemistry | Terpenes - chemistry | Water - chemistry | Microscopy, Atomic Force | Molecular Structure | Diffusion | Transdermal Patch | Rheology | Salicylates - administration & dosage | Solubility | Technology, Pharmaceutical - methods | Diphenhydramine - chemistry | Chemistry, Pharmaceutical | Calorimetry, Differential Scanning | Kinetics | Chromatography, Gel | Drugs | Atomic force microscopy | Drug delivery systems | Thermoplastics | Digoxin | Analysis | Elastomers | Esters | Medicine, Chinese | Diphenhydramine | Transdermal medication | Vehicles | Drugstores | Polymers | Competition | I.R. spectroscopy | Differential scanning calorimetry | Salicylic acid | Plasticizers | Capsaicin | X-ray diffraction | Drug delivery | Coatings | Drug development | atomic force microscopy | Adhesives | Mathematical models | Models | diphenhydramine
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2005, Volume 353, Issue 2, pp. 334 - 344
In mammals, histamine action is terminated through metabolic inactivation by histamine N-methyltransferase (HNMT) and diamine oxidase. In addition to three... 
amodiaquine | tacrine | metoprine | diphenhydramine | HNMT inhibitors | Amodiaquine | Metoprine | Diphenhydramine | Tacrine | MONOAMINE-OXIDASE | H-3 RECEPTOR | BRAIN HISTAMINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAST-CELLS | ESCHERICHIA-COLI | LOCOMOTOR-ACTIVITY | DEFICIENT MICE | RAT-BRAIN | Folic Acid Antagonists - chemistry | Histamine N-Methyltransferase - chemistry | Histamine N-Methyltransferase - metabolism | Humans | Cholinesterase Inhibitors - chemistry | Crystallography, X-Ray | Amodiaquine - chemistry | Pyrimethamine - metabolism | Amodiaquine - metabolism | Histamine H1 Antagonists - metabolism | Cholinesterase Inhibitors - metabolism | Diphenhydramine - metabolism | Pyrimethamine - analogs & derivatives | Molecular Structure | Tacrine - chemistry | Pyrimethamine - chemistry | Tacrine - metabolism | Antimalarials - metabolism | Models, Molecular | Diphenhydramine - chemistry | Animals | Folic Acid Antagonists - metabolism | Antimalarials - chemistry | Protein Conformation | Histamine N-Methyltransferase - antagonists & inhibitors | Histamine H1 Antagonists - chemistry | Oxidases | Histamine | Permeability | Cholinesterase inhibitors | Alzheimer's disease | STIMULATION | PERMEABILITY | BASIC BIOLOGICAL SCIENCES | CELL PROLIFERATION | national synchrotron light source | INACTIVATION | CONTRACTION | AROMATICS | GASTRIC ACID | HISTAMINE | REGULATIONS | SECRETION | PROTEINS | RESIDUES | MUSCLES | MAMMALS
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