X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3209) 3209
Book Review (381) 381
Publication (226) 226
Newsletter (45) 45
Book / eBook (10) 10
Conference Proceeding (8) 8
Magazine Article (7) 7
Book Chapter (5) 5
Dissertation (3) 3
Transcript (2) 2
Web Resource (2) 2
Data Set (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (2393) 2393
humans (1527) 1527
animals (1045) 1045
diphosphonates - pharmacology (873) 873
diphosphonates - chemistry (794) 794
diphosphonates (767) 767
female (748) 748
diphosphonates - therapeutic use (727) 727
bisphosphonates (712) 712
male (641) 641
osteoporosis (499) 499
zoledronic acid (449) 449
bisphosphonate (418) 418
phosphonates (390) 390
rats (380) 380
diphosphonates - administration & dosage (377) 377
biochemistry & molecular biology (366) 366
endocrinology & metabolism (361) 361
mice (355) 355
chemistry, inorganic & nuclear (349) 349
middle aged (340) 340
aged (321) 321
in-vitro (314) 314
alendronate (305) 305
analysis (298) 298
pharmacology & pharmacy (297) 297
bone density conservation agents - therapeutic use (282) 282
chemistry, multidisciplinary (272) 272
bone (258) 258
research (256) 256
diphosphonates - adverse effects (233) 233
imidazoles - pharmacology (228) 228
bones (227) 227
orthopedics (227) 227
diphosphonate (226) 226
cell biology (218) 218
chemistry (212) 212
cancer (202) 202
chemistry, medicinal (201) 201
oncology (199) 199
bone density conservation agents - pharmacology (196) 196
adult (193) 193
bone density - drug effects (193) 193
pamidronate (189) 189
cell line, tumor (179) 179
drug therapy (178) 178
nitrogen-containing bisphosphonates (178) 178
bone density conservation agents - administration & dosage (175) 175
imidazoles - therapeutic use (173) 173
bone neoplasms - secondary (172) 172
osteoporosis - drug therapy (172) 172
molecular structure (170) 170
diphosphonates - metabolism (169) 169
dose-response relationship, drug (167) 167
apoptosis (163) 163
crystal-structures (162) 162
care and treatment (160) 160
complexes (159) 159
hydrothermal synthesis (159) 159
postmenopausal women (158) 158
time factors (158) 158
bone-resorption (157) 157
diphosphonates - chemical synthesis (157) 157
bone and bones - metabolism (154) 154
therapy (153) 153
bone neoplasms - drug therapy (150) 150
treatment outcome (150) 150
diphosphonates - pharmacokinetics (149) 149
ligands (148) 148
breast-cancer (147) 147
endocrinology (147) 147
abridged index medicus (145) 145
article (145) 145
bone resorption (145) 145
imidazoles - administration & dosage (145) 145
structure-activity relationship (145) 145
bone and bones - drug effects (142) 142
cells, cultured (139) 139
biochemistry, general (137) 137
life sciences (137) 137
acid (135) 135
fractures (134) 134
health aspects (134) 134
medicine & public health (134) 134
models, molecular (134) 134
inhibition (133) 133
aged, 80 and over (132) 132
bone density conservation agents - adverse effects (132) 132
chemistry, physical (132) 132
in-vivo (132) 132
dentistry (131) 131
osteoclasts - drug effects (129) 129
crystal structure (127) 127
bone density (125) 125
chemistry, organic (125) 125
drugs (124) 124
cells (123) 123
metastasis (122) 122
osteoclasts (122) 122
postmenopausal osteoporosis (122) 122
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3213) 3213
German (22) 22
Chinese (16) 16
French (13) 13
Japanese (10) 10
Polish (4) 4
Russian (4) 4
Spanish (4) 4
Italian (2) 2
Danish (1) 1
Norwegian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Coordination Chemistry Reviews, ISSN 0010-8545, 11/2015, Volume 303, pp. 86 - 109
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 02/2017, Volume 95, pp. 1022 - 1036
Cardiotoxins (CTXs) are single polypeptide chain consisting of 59–62 amino acids with four disulfide bridges and globular proteins of simple β-sheet folds. The... 
Molecular dynamics | Snake venom | Heterogeneous bilayer | Inhibitors | RBC lysis | STRUCTURAL STABILITY | INDIAN COBRA | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPASE A | PLASMA-MEMBRANE | UNFOLDING STABILITIES | AMINO-ACID-SEQUENCE | BETA-SHEET PROTEIN | WITHANIA-SOMNIFERA | CHEMISTRY, APPLIED | TAIWAN COBRA | CHEMICAL MODIFICATION | Elapid Venoms - chemistry | Hemolysis - drug effects | Small Molecule Libraries - pharmacology | User-Computer Interface | Humans | Imidazoles - chemistry | Structure-Activity Relationship | Cobra Cardiotoxin Proteins - chemistry | Cobra Cardiotoxin Proteins - antagonists & inhibitors | Cholesterol - chemistry | Disulfides - chemistry | Protein Domains | Elapid Venoms - isolation & purification | Cobra Cardiotoxin Proteins - isolation & purification | Antidotes - pharmacology | Elapid Venoms - toxicity | Amino Acid Sequence | Antidotes - chemistry | Protein Structure, Secondary | Phosphatidylserines - chemistry | Cobra Cardiotoxin Proteins - toxicity | Elapid Venoms - antagonists & inhibitors | Imidazoles - pharmacology | Phosphatidylcholines - chemistry | Erythrocyte Membrane - drug effects | Molecular Dynamics Simulation | Small Molecule Libraries - chemistry | Animals | Etidronic Acid - pharmacology | High-Throughput Screening Assays | Diphosphonates - chemistry | Elapidae - metabolism | Erythrocyte Membrane - chemistry | Etidronic Acid - chemistry | Phosphatidylethanolamines - chemistry | Diphosphonates - pharmacology | Venom | Investigations | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 25, pp. 6918 - 6929
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 82, pp. 178 - 193
Abstract Zoledronate (Zol) is a third-generation bisphosphonate that is widely used as an anti-resorptive agent for the treatment of cancer bone metastasis.... 
Advanced Basic Science | Dentistry | Folate-targeted nanoscale metal-organic frameworks | Chemotherapy | Drug delivery | Zoledronate | Cancer | CANCER-CELLS | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | METASTASES | PHOSPHATE NANOCOMPOSITE PARTICLES | FOLIC-ACID | DOSE-RANGING TRIAL | NANOPARTICLES | BISPHOSPHONATES | COORDINATION POLYMERS | PHASE-I | Nanocomposites - chemistry | Apoptosis - drug effects | Humans | Imidazoles - chemistry | Imidazoles - administration & dosage | Delayed-Action Preparations - chemistry | Antineoplastic Agents - administration & dosage | Calcium - chemistry | Nanocapsules - chemistry | Delayed-Action Preparations - administration & dosage | Neoplasms, Experimental - pathology | Metals - chemistry | Bone Density Conservation Agents | Cell Survival - drug effects | Folic Acid - chemistry | Organic Chemicals - chemistry | Treatment Outcome | Diphosphonates - administration & dosage | Zoledronic Acid | Antineoplastic Agents - chemistry | Folic Acid - pharmacokinetics | Diphosphonates - chemistry | Cell Line, Tumor | Neoplasms, Experimental - drug therapy | Hydrogen-Ion Concentration | Drugs | Drug delivery systems | Care and treatment | Phosphonates | Lung cancer, Non-small cell | Polyols | Folic acid | Vehicles | Analysis | Health aspects | Prostate cancer | Nanotechnology | Index Medicus | Polyethylene glycol | Bones | Nanostructure | Prostate | Metal-organic frameworks | Apoptosis | Tumors | Anticancer properties
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2016, Volume 235, pp. 365 - 378
Osteoinduction can be enhanced by combining scaffolds with bone morphogenic protein-2 (BMP-2). However, BMP's are known to also cause bone resorption. This can... 
Zoledronic acid | Bone tissue engineering | Biomaterial | Biocomposite | Cryogel | GROWTH-FACTOR DELIVERY | VIVO | TISSUE | SILK FIBROIN | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | PHARMACOLOGY & PHARMACY | BIOMATERIALS | DIFFERENTIATION | LOCAL TREATMENT | COLLAGEN-HYDROXYAPATITE SCAFFOLDS | Fibroins - chemistry | Cryogels - chemistry | Alkaline Phosphatase - metabolism | Imidazoles - chemistry | Drug Carriers - administration & dosage | Imidazoles - administration & dosage | Bone Morphogenetic Protein 2 - chemistry | Male | Glass - chemistry | Drug Carriers - chemistry | Cryogels - administration & dosage | Bone Morphogenetic Protein 2 - administration & dosage | Cell Line | Osteogenesis - drug effects | Recombinant Proteins - chemistry | Durapatite - chemistry | Bone Regeneration | Diphosphonates - administration & dosage | Rats, Sprague-Dawley | Recombinant Proteins - administration & dosage | Animals | Chitosan - chemistry | Sepharose - chemistry | Diphosphonates - chemistry | Cell Proliferation - drug effects | Mice | Porosity | Analysis | Phosphatases | Biological products | Tissue engineering | Index Medicus | Biomaterials Science | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinteknik | Medicinsk bioteknologi | Biomaterialvetenskap | Teknik | Medical Biotechnology | Engineering and Technology | Medical Engineering | Medical Materials | Medicinsk material- och protesteknik
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2009, Volume 131, Issue 25, pp. 8781 - 8783
We present here a novel synthesis route to functionalize high molecular weight hyaluronan (HMW-HA) with a hydrazide group and a bioactive ligand, namely... 
VITRO | APOPTOSIS | ACID | DOXORUBICIN | GROWTH | INTRACELLULAR DELIVERY | SIRNA | CHEMISTRY, MULTIDISCIPLINARY | CD44 | COLON-CARCINOMA CELLS | Hydrogel, Polyethylene Glycol Dimethacrylate - toxicity | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Hyaluronoglucosaminidase - metabolism | Antineoplastic Agents - chemical synthesis | Humans | Hyaluronic Acid - toxicity | Hydrazines - toxicity | Drug Carriers - toxicity | Prodrugs - chemistry | Drug Carriers - chemistry | Prodrugs - metabolism | Antineoplastic Agents - toxicity | Antineoplastic Agents - metabolism | Hydrazines - chemistry | Hydrazines - chemical synthesis | Colorectal Neoplasms - drug therapy | Diphosphonates - chemical synthesis | Hyaluronan Receptors - metabolism | Colorectal Neoplasms - metabolism | Diphosphonates - toxicity | Hydrogel, Polyethylene Glycol Dimethacrylate - metabolism | Cell Line | Cell Survival - drug effects | Drug Carriers - metabolism | Hyaluronic Acid - chemistry | Diphosphonates - metabolism | Drug Carriers - chemical synthesis | Kidney - cytology | Antineoplastic Agents - chemistry | Hydrazines - metabolism | Diphosphonates - chemistry | Hyaluronic Acid - metabolism | Prodrugs - toxicity | Cell Line, Tumor | Hyaluronic Acid - chemical synthesis | Prodrugs - chemical synthesis | Hydrogel, Polyethylene Glycol Dimethacrylate - chemical synthesis | Index Medicus | Chemistry | Naturvetenskap | Kemi | Oorganisk kemi | Natural Sciences | Inorganic Chemistry | Chemical Sciences
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2013, Volume 21, Issue 21, pp. 6456 - 6465
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2007, Volume 129, Issue 42, pp. 12638 - 12639
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 11, pp. 4058 - 4063
We report the results of an in vitro screening assay targeting the intraerythrocytic form of the malaria parasite Plasmodium falciparum using a library of 560... 
Molecules | Enzymes | Diphosphonates | Dimers | Diphosphates | Inhibitory concentration 50 | Parasitemia | Molecular chains | Crystal structure | Tunnels | BISPHOSPHONATES | TRYPANOSOMA-BRUCEI | INTRAERYTHROCYTIC STAGES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | FARNESYL PYROPHOSPHATE SYNTHASE | TOXOPLASMA-GONDII | ENTAMOEBA-HISTOLYTICA | HUMAN BONE | LEISHMANIA-DONOVANI | Plasmodium falciparum - enzymology | Plasmodium - enzymology | Humans | Imidazoles - chemistry | Crystallography, X-Ray | Parasitemia - drug therapy | Plasmodium - drug effects | Plasmodium falciparum - drug effects | Farnesyltranstransferase - metabolism | Terpenes - chemistry | Lipids - chemistry | Terpenes - metabolism | Enzyme Inhibitors - chemistry | Protein Binding - drug effects | Diphosphonates - therapeutic use | Farnesyltranstransferase - antagonists & inhibitors | Etidronic Acid - therapeutic use | Imidazoles - therapeutic use | Risedronate Sodium | Etidronic Acid - analogs & derivatives | Plasmodium vivax - enzymology | Plasmodium vivax - drug effects | Enzyme Inhibitors - pharmacology | Models, Molecular | Antimalarials - therapeutic use | Imidazoles - pharmacology | Antimalarials - pharmacology | Erythrocytes - drug effects | Farnesyltranstransferase - chemistry | Animals | Etidronic Acid - pharmacology | High-Throughput Screening Assays | Diphosphonates - chemistry | Antimalarials - chemistry | Survival Analysis | Parasitemia - parasitology | Calorimetry | Mice | Erythrocytes - parasitology | Etidronic Acid - chemistry | Diphosphonates - pharmacology | Risedronate | Microbiological chemistry | Plasmodium falciparum | Chemical properties | Research | Pyrophosphates | Parasites | Molecular structure | Enzyme kinetics | Rodents | Cells | Index Medicus | Physical Sciences | calorimetry | crystallography | drug discovery | high-throughput screening
Journal Article