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PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 5, pp. e10498 - e10498
Background: Diphtheria toxin (DT) has been utilized as a prospective anti-cancer agent for the targeted delivery of cytotoxic therapy to otherwise untreatable... 
DENILEUKIN DIFTITOX | COLONY-STIMULATING FACTOR | MOUSE MODEL | IN-VIVO | BIOLOGY | FACTOR FUSION PROTEIN | CYNOMOLGUS MONKEYS | ACUTE MYELOID-LEUKEMIA | GROWTH-FACTOR | EXPRESSION | CYTOTOXICITY | Cell Survival - drug effects | Diphtheria Toxin - pharmacology | Endocytosis - drug effects | Humans | Chorioallantoic Membrane - metabolism | Neoplasms - blood supply | Chick Embryo | Mutant Proteins - pharmacology | Neovascularization, Pathologic - pathology | Xenograft Model Antitumor Assays | Animals | Cattle | Chorioallantoic Membrane - drug effects | Cell Line, Tumor | Protein Biosynthesis - drug effects | Cell Proliferation - drug effects | Mice | Neovascularization, Pathologic - metabolism | Cell Death - drug effects | Neoplasms - pathology | Proteins | Care and treatment | Lung cancer | Analysis | Cancer cells | Protein biosynthesis | Cancer | Protein binding | Cell proliferation | Biotechnology | Phosphorylation | Toxicity | Lung | Cytotoxicity | Biosynthesis | Biochemistry | Anticancer properties | Angiogenesis | Cell growth | Antitumor agents | Penicillin | Fibroblasts | Biocompatibility | Inhibition | Catalysis | Diphtheria toxin | Growth factors | Deoxyribonucleic acid--DNA | Recombinant | Departments | Pulmonary arteries | Cloning | Pharmacology | Lung carcinoma | Tumor cell lines | Diphtheria | Gene expression | Embryos | Chemical compounds | Endothelium | Pathology | Chorioallantoic membrane | Protein synthesis | In vivo methods and tests | Molecular biology | In vitro methods and tests | Prostate | Tumors | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nature, ISSN 0028-0836, 04/2010, Volume 464, Issue 7292, pp. 1149 - 1154
Journal Article
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 09/2017, Volume 448, pp. 51 - 58
Ontak® is a FDA-approved diphtheria toxin-based recombinant fusion toxin for treatment of human CD25 cutaneous T cell lymphoma (CTCL). However, it has been... 
Ontak | CD25 | Pichia Pastoris | Diphtheria toxin | CTCL | IL-2 fusion toxin | DENILEUKIN DIFTITOX | DIPHTHERIA | BIOCHEMICAL RESEARCH METHODS | T-CELL LYMPHOMA | IMMUNOLOGY | IMMUNOTOXIN | CD25(+) CELLS | Immunoconjugates - toxicity | Diphtheria Toxin - pharmacology | Skin Neoplasms - drug therapy | Recombinant Fusion Proteins - pharmacology | Lymphoma, T-Cell, Cutaneous - immunology | Humans | Diphtheria Toxin - toxicity | Lymphoma, T-Cell, Cutaneous - drug therapy | Antineoplastic Agents - toxicity | Antineoplastic Agents - metabolism | Dose-Response Relationship, Drug | Immunoconjugates - pharmacology | Pichia - metabolism | Time Factors | Antineoplastic Agents - pharmacology | Interleukin-2 Receptor alpha Subunit - immunology | Skin Neoplasms - pathology | Skin Neoplasms - immunology | Immunoconjugates - metabolism | Recombinant Fusion Proteins - toxicity | Mice, SCID | Interleukin-2 - toxicity | Safety-Based Drug Withdrawals | Mice, Knockout | Lymphoma, T-Cell, Cutaneous - pathology | Xenograft Model Antitumor Assays | Interleukin-2 - genetics | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Tumor Burden - drug effects | Immunoconjugates - genetics | Pichia - genetics | Cell Line, Tumor | Interleukin-2 - pharmacology | Mice, Inbred NOD | Interleukin-2 - biosynthesis | Non-Hodgkin's lymphomas | T cells | Drug approval | Analysis | Index Medicus | diphtheria toxin
Journal Article
Kidney International, ISSN 0085-2538, 10/2012, Volume 82, Issue 8, pp. 928 - 933
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 5/1998, Volume 141, Issue 4, pp. 905 - 915
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1748, pp. 203 - 228
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Journal Article
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