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PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 11, pp. e112945 - e112945
The kynurenine pathway (KP) is the principal route of L-tryptophan (TRP) catabolism leading to the production of kynurenine (KYN), the neuroprotectants,... 
OXIDATIVE STRESS | QUINOLINIC ACID | MAMMALIAN BRAIN | POOR-PROGNOSIS | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | TRYPTOPHAN 2,3-DIOXYGENASE | TUMORAL IMMUNE RESISTANCE | T-CELLS | IDO EXPRESSION | BRAIN-TUMORS | Immunohistochemistry | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Kynurenic Acid - blood | Gene Expression - drug effects | Humans | Kynurenine - biosynthesis | Brain Neoplasms - physiopathology | Picolinic Acids - blood | Quinolinic Acid - blood | Chromatography, High Pressure Liquid | Glial Fibrillary Acidic Protein - metabolism | Kynurenic Acid - metabolism | Carboxy-Lyases - genetics | Tryptophan - metabolism | Brain Neoplasms - metabolism | Picolinic Acids - metabolism | Antigens, CD - metabolism | Glioma - metabolism | Glioma - genetics | Kynurenine - blood | Tryptophan - blood | Carboxy-Lyases - metabolism | Tumor Cells, Cultured | Astrocytes - drug effects | Disaccharides | Cells, Cultured | Brain Neoplasms - genetics | Biosynthetic Pathways | Reverse Transcriptase Polymerase Chain Reaction | Glucuronates | Tryptophan Oxygenase - metabolism | Tryptophan Oxygenase - genetics | Antigens, Differentiation, Myelomonocytic - metabolism | Quinolinic Acid - metabolism | CD11b Antigen - metabolism | Glioma - physiopathology | Interferon-gamma - pharmacology | Astrocytes - metabolism | Tryptophan | Niacinamide | Methyl aspartate | Enzymes | Metabolites | Gliomas | NADPH | Neuroprotection | Brain | Brain tumors | Brain cancer | Glioblastoma | Tryptophan 2,3-dioxygenase | Immunity | DNA repair | Picolinic acid | Rodents | Glioma cells | L-Tryptophan | Kynurenic acid | Quinolinic acid | Deoxyribonucleic acid--DNA | Pyridines | Medical research | Hydroxylase | Adenine | Kynurenine-oxoglutarate transaminase | NAD | Acids | γ-Interferon | Nicotinamide adenine dinucleotide | Catabolism | Nicotinamide | Interferon | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2011, Volume 6, Issue 10, pp. e26214 - e26214
Ecological performance is all about timing and the endogenous clock that allows the entrainment of rhythms and anticipation of fitness-determining events is... 
CIRCADIAN CLOCK | MOLECULAR-INTERACTIONS | ARABIDOPSIS ROOTS | INSECT HERBIVORES | BIOLOGY | GENE-EXPRESSION | MANDUCA-SEXTA LEPIDOPTERA | TYROSINE DECARBOXYLASE | JASMONIC ACID | AMINO-ACID CONTENT | DITERPENE GLYCOSIDES | Disaccharides - metabolism | Plant Roots - genetics | Manduca - metabolism | RNA, Messenger - metabolism | Plant Roots - drug effects | Plant Roots - physiology | Plant Leaves - drug effects | Tobacco - physiology | Phenylalanine - metabolism | Plant Roots - metabolism | Tobacco - metabolism | Larva - metabolism | RNA, Messenger - genetics | Circadian Rhythm - genetics | Tobacco - drug effects | Herbivory | Fatty Acids, Unsaturated - metabolism | Organ Specificity | Polyamines - metabolism | Oxylipins - metabolism | Tyrosine - metabolism | Animals | Plant Leaves - genetics | Plant Leaves - metabolism | Genes, Plant - genetics | Glycosides - metabolism | Tobacco - genetics | Cyclopentanes - metabolism | Mechanical Phenomena | Plant Leaves - physiology | Metabolites | Animal behavior | Analysis | Physiological aspects | Liquid chromatography | Mass spectrometry | Health aspects | Larvae | Roots | Tissues | Accumulation | Leaves | Entrainment | Drought | Jasmonic acid | Tyrosine | Tyramine | Stresses | Plants (botany) | Computer simulation | Phenylalanine | Mass spectroscopy | Ions | Rhythms | Circadian rhythm | Metabolism | Diurnal | Tobacco | Acids | Insects | Herbivores | Fitness | Index Medicus
Journal Article
Science, ISSN 0036-8075, 11/2011, Volume 334, Issue 6059, pp. 1097 - 1103
The HIV envelope (Env) protein gpl20 is protected from antibody recognition by a dense glycan shield. However, several of the recently identified PGT broadly... 
Polysaccharides | HIV | Neutralizing antibodies | RESEARCH ARTICLES | Antibodies | Viruses | Trimers | Epitopes | Grants | Binding sites | Crystal structure | PANEL | TRIMERS | MULTIDISCIPLINARY SCIENCES | IMMUNOGENS | ENVELOPE GLYCOPROTEIN COMPLEX | GP120 | HUMAN-IMMUNODEFICIENCY-VIRUS | MONOCLONAL-ANTIBODIES | TYPE-1 | Antibody Specificity | Mannose - immunology | Disaccharides - metabolism | Humans | Antibodies, Neutralizing - metabolism | Crystallography, X-Ray | Disaccharides - chemistry | Mannosides - chemistry | HIV Envelope Protein gp120 - metabolism | HIV Envelope Protein gp120 - immunology | Mannose - metabolism | Antibodies, Neutralizing - immunology | HIV-1 - physiology | HIV Antibodies - immunology | Immunoglobulin Fab Fragments - metabolism | Oligosaccharides - chemistry | Polysaccharides - chemistry | HIV Envelope Protein gp120 - chemistry | Mannose - chemistry | HIV Antibodies - metabolism | Protein Structure, Tertiary | Cell Line | Models, Molecular | Antibodies, Neutralizing - genetics | Glycosylation | Polysaccharides - immunology | Oligosaccharides - metabolism | HIV Antibodies - chemistry | Polysaccharides - metabolism | HIV-1 - immunology | Hydrogen Bonding | Antibodies, Neutralizing - chemistry | Immunoglobulin Fab Fragments - chemistry | Oligosaccharides - immunology | Protein Conformation | Mannosides - metabolism | HIV Antibodies - genetics | Immunoglobulin Fab Fragments - immunology | Mutation | Binding Sites, Antibody | Carbohydrate Conformation | Viral antibodies | Physiological aspects | Development and progression | Glycoproteins | HIV (Viruses) | Health aspects | Proteins | Antigens | Immunoglobulins | Human immunodeficiency virus--HIV | Index Medicus
Journal Article
Plant Physiology, ISSN 0032-0889, 12/2011, Volume 157, Issue 4, pp. 1696 - 1710
Journal Article
Journal of nutrition, ISSN 0022-3166, 2008, Volume 138, Issue 8, pp. 1417 - 1420
Journal Article
The Plant Cell, ISSN 1040-4651, 10/2014, Volume 26, Issue 10, pp. 3949 - 3963
Bud dormancy is an adaptive strategy that perennials use to survive unfavorable conditions. Gentians (Gentiana), popular alpine flowers and ornamentals,... 
Dormancy | Cooling | Metabolites | Plant growth regulators | RESEARCH ARTICLES | Amino acids | Budbreak | Plants | Amino acid metabolism | Sugars | Plant cells | ARABIDOPSIS-THALIANA | LEAFY SPURGE | GROWTH CESSATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | UNDERGROUND ADVENTITIOUS BUDS | FLOWERING-LOCUS-T | COLD-ACCLIMATION | POTATO MICROTUBER DORMANCY | FREEZING-TOLERANCE | PLANT SCIENCES | CELL BIOLOGY | CELL-CYCLE | SPURGE EUPHORBIA-ESULA | Carbohydrate Metabolism - drug effects | Gentiana - genetics | Disaccharides - metabolism | Glutathione - metabolism | Meristem - physiology | Carbohydrate Metabolism - genetics | Molecular Sequence Data | Ascorbic Acid - metabolism | beta-Fructofuranosidase - genetics | Amino Acids - metabolism | Disaccharides - pharmacology | Meristem - genetics | Meristem - metabolism | Plant Proteins - metabolism | Seasons | Hexokinase - genetics | Phosphoglucomutase - metabolism | beta-Fructofuranosidase - metabolism | Disaccharides - physiology | Reverse Transcriptase Polymerase Chain Reaction | Metabolomics - methods | Metabolome - genetics | Gentiana - metabolism | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Metabolic Networks and Pathways - genetics | Metabolic Networks and Pathways - drug effects | Hexokinase - metabolism | Phosphoglucomutase - genetics | Gentiana - physiology | Botanical research | Protein research | Gentian root | Growth | Physiological aspects | Research | Oligosaccharides | Growth (Plants) | Gentiana | Index Medicus
Journal Article
BBA - General Subjects, ISSN 0304-4165, 07/2018, Volume 1862, Issue 7, pp. 1592 - 1601
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 09/2015, Volume 114, Issue 11, pp. 1774 - 1783
Obesity is one of the major health problems throughout the world. The present study investigated the preventive effect of epilactose - a rare non-digestible... 
Obesity | Uncoupling protein | Epilactose | Propionic acid | Skeletal muscle | LIPID-METABOLISM | OLIGOSACCHARIDES | RATS | BROWN ADIPOSE-TISSUE | GUT MICROBIOTA | IDENTIFICATION | NUTRITION & DIETETICS | INSULIN-RESISTANCE | ENERGY-METABOLISM | TRANSGENIC MICE | Propionates - metabolism | Up-Regulation | Adipose Tissue, White - immunology | Disaccharides - metabolism | Obesity - immunology | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Ion Channels - genetics | Male | Muscle, Skeletal - metabolism | Mitochondrial Proteins - genetics | Mitochondrial Proteins - agonists | Obesity - microbiology | Anti-Obesity Agents - therapeutic use | Muscle, Skeletal - immunology | Mitochondrial Proteins - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Disaccharides - therapeutic use | Adipose Tissue, Brown - immunology | Anti-Obesity Agents - metabolism | Adipose Tissue, White - pathology | Cell Line | Mice, Inbred C57BL | Gastrointestinal Microbiome | Random Allocation | Fermentation | Adipose Tissue, Brown - pathology | Macrophage Activation | Obesity - metabolism | Prebiotics | Animals | Energy Metabolism | Ion Channels - metabolism | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Obesity - prevention & control | Ion Channels - agonists | Adipose Tissue, Brown - metabolism | Uncoupling Protein 1 | Proteins | Nutrition research | Rodents | Metabolic disorders | Dietary supplements | Index Medicus
Journal Article
Sensors, ISSN 1424-8220, 11/2011, Volume 11, Issue 11, pp. 10638 - 10663
Cadmium, as a hazardous pollutant commonly present in the living environment, represents an important risk to human health due to its undesirable effects... 
Cadmium | Brdicka reaction | Metabolic activity | Biosensor | Electrochemistry | Metabolome | High performance liquid chromatography with electrochemical detection | Voltammetry | Spectrophotometry | Staphylococcus aureus | Microbiome | ENVIRONMENTAL-POLLUTION | BACTERIAL BIOSENSORS | CHEMISTRY, ANALYTICAL | MERCURY DROP ELECTRODE | biosensor | voltammetry | electrochemistry | microbiome | metabolic activity | spectrophotometry | INSTRUMENTS & INSTRUMENTATION | METALLOTHIONEIN DETECTION | LIQUID-CHROMATOGRAPHY | high performance liquid chromatography with electrochemical detection | INTEGRATED-CIRCUITS | cadmium | HEAVY-METAL RESISTANCE | WHOLE-CELL BIOSENSORS | ELECTROCHEMICAL TECHNIQUES | AMPEROMETRIC DETECTION | metabolome | Hydrolases - metabolism | Metallothionein - metabolism | Electrochemical Techniques | Disaccharides - metabolism | Glutathione - metabolism | Cadmium - pharmacology | Environmental Pollutants - pharmacology | Glutathione Transferase - metabolism | Glutathione Disulfide - metabolism | Cadmium - metabolism | Environmental Pollutants - metabolism | Sulfhydryl Compounds - metabolism | Proteins - metabolism | Metabolism - drug effects | Staphylococcus aureus - cytology | Biosensing Techniques - methods | Cadmium - analysis | Urease - metabolism | Cell Proliferation - drug effects | Monosaccharides - metabolism | Phosphoric Monoester Hydrolases - metabolism | Staphylococcus aureus - drug effects | Environmental Pollutants - analysis | Staphylococcus aureus - metabolism | Index Medicus
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 02/2016, Volume 220, pp. 25 - 32
The enzymatic bioconversion of chitin is of considerable interest for the natural production of bioactive compounds such as chitooligosaccharides and -acetyl-... 
Carbohydrates | Biotechnology | Bioconversion | Glucosamine | Enzyme | SERRATIA-MARCESCENS 2170 | HYDROLYSIS | ACETYL-D-GLUCOSAMINE | PROCESSIVITY | ENZYMATIC PRODUCTION | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SUBSTRATE | DEGRADATION | CRUDE ENZYMES | BETA-CHITIN | Streptomyces coelicolor - genetics | Acetylglucosamine - biosynthesis | Disaccharides - metabolism | Streptomyces lividans - metabolism | Chitinases - metabolism | Glucosamine - metabolism | Acetylglucosamine - metabolism | Chitinases - genetics | Streptomyces coelicolor - metabolism | Chitin - analogs & derivatives | Hexosaminidases - metabolism | Plant Proteins - chemistry | Chitin - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Plant Proteins - metabolism | Chitinases - chemistry | Plant Proteins - isolation & purification | Recombinant Proteins - metabolism | Soil Microbiology | Bacterial Proteins - genetics | Enzyme Stability | Recombinant Proteins - chemistry | Chitin - chemistry | Hydrolysis | Plant Proteins - genetics | Chitinases - isolation & purification | Escherichia coli - genetics | Streptomyces coelicolor - enzymology | Bacterial Proteins - metabolism | Enzyme Activation | Chitin | Enzymes | Escherichia coli | Soil microbiology | Index Medicus | Chitinase | Streptomyces coelicolor | Biocompatibility | Crystal structure | Life Sciences
Journal Article