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Biochemical Journal, ISSN 0264-6021, 04/2010, Volume 427, Issue 1, pp. 69 - 78
More than 200 phosphorylated 14-3-3-binding sites in the literature were analysed to define 14-3-3 specificities, identify relevant protein kinases, and give... 
Evolution | 14-3-3 protein | Disrupted-in-schizophrenia 1 (DISC1) | calmodulin-dependent protein kinase | AGC protein kinase | NEURONAL MIGRATION | SIGNALING PATHWAYS | MEMBRANE H+-ATPASE | REGULATING 14-3-3 BINDING | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EUKARYOTIC PROTEIN-KINASES | evolution | NUCLEAR-LOCALIZATION | EXOENZYME-S | STRUCTURAL BASIS | Ca2+/calmodulin-dependent protein kinase | disrupted-in-schizophrenia 1 (DISC1) | ENDOPLASMIC-RETICULUM | Protein Kinases - metabolism | Phosphorylation | Immunoprecipitation | Humans | RNA, Messenger - genetics | Cells, Cultured | Computational Biology | Kidney - cytology | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | 14-3-3 Proteins - metabolism | Nerve Tissue Proteins - metabolism | Kidney - metabolism | Carrier Proteins - metabolism | Protein Binding | Binding Sites | Dimerization | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | 14-3-3 Proteins - genetics | Index Medicus | Bcl-2-associated death promoter | AANAT, serotonin acetyltransferase | FOXO, Forkhead box O | KLC, kinesin light chain | CDK5, cyclin-dependent kinase 5 | HEK, human embryonic kidney | MARK, microtubule affinity-regulating kinase | AMPK, AMP-activated protein kinase | EST, expressed sequence tag | PKB, protein kinase B | RSK, ribosomal S6 kinase | CaMK, Ca2 | GLUT4, glucose transporter 4 | protein kinase G | GST, glutathione transferase | HDAC, histone deacetylase | HAP1A, Huntingtin-associated protein 1A | DIG, digoxigenin | PKC, protein kinase C | BAD, Bcl-XL | PP2A, protein phosphatase 2A | DSTT, Division of Signal Transduction Therapy | HA, haemagglutinin | AGC, protein kinase A | Ca2 | PI4K, phosphoinositide 4-kinase | DISC1, disrupted-in-schizophrenia 1 | protein kinase C family kinase | YAP1, yes-associated protein 1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 12, pp. 5622 - 5627
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Neuron, ISSN 0896-6273, 09/2009, Volume 63, Issue 6, pp. 774 - 787
( ), a susceptibility gene for major psychiatric disorders, regulates neuronal migration and differentiation during mammalian brain development. Although roles... 
SYSNEURO | DEVBIO | MOLNEURO | NEURODEVELOPMENT | HIPPOCAMPUS | CELLS | NEURITE OUTGROWTH | ADULT NEUROGENESIS | NEURONAL POLARITY | MECHANISMS | DISC1 | NEUROSCIENCES | BRAIN | DISRUPTED-IN-SCHIZOPHRENIA-1 | Membrane Potentials - genetics | Embryo, Mammalian | Vesicular Transport Proteins - metabolism | Humans | Cercopithecus aethiops | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Cell Movement - genetics | Neurogenesis - genetics | Cell Differentiation - genetics | Dentate Gyrus - embryology | Transfection - methods | Neurons - physiology | Microfilament Proteins - metabolism | Bromodeoxyuridine - metabolism | RNA Interference - physiology | Electric Stimulation - methods | Microfilament Proteins - genetics | Animals, Newborn | Membrane Potentials - drug effects | Growth Cones - physiology | Microfilament Proteins - deficiency | Immunoprecipitation - methods | Mice, Inbred C57BL | Vesicular Transport Proteins - genetics | Cells, Cultured | Rats | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Dentate Gyrus - cytology | Patch-Clamp Techniques | Animals | Vesicular Transport Proteins - deficiency | Analysis of Variance | Neurogenesis - physiology | Dentate Gyrus - growth & development | Protein Binding | Mice | Protein Structure, Tertiary - physiology | Infants (Newborn) | Medical colleges | Neurosciences | Evolutionary biology | RNA | Neurons | Binding proteins | Mental illness | Proteins | Medical research | Brain research | Rodents | Migration | Technological change | Schizophrenia | Kinases | Binding sites | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 12/2017, Volume 96, Issue 5, pp. 1041 - 1054.e5
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2015, Volume 5, Issue 1, pp. 16300 - 16300
Mutated disrupted in schizophrenia 1 (DISC1), a microtubule regulating protein, leads to schizophrenia and other psychiatric illnesses. It is hypothesized that... 
LANGUAGE | NEUROPROTECTIVE PEPTIDE | WEANING SOCIAL-ISOLATION | FOXP2 POLYMORPHISMS | MULTIDISCIPLINARY SCIENCES | SPEECH | DEFICITS | DISC1 | ELEVATED PLUS-MAZE | BRAIN | DAVUNETIDE | Microtubule-Associated Proteins - chemistry | Schizophrenia - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Male | Schizophrenia - pathology | Neuroprotective Agents - metabolism | Neuroprotective Agents - pharmacology | Schizophrenia - genetics | Female | Binding Sites | Oligopeptides - chemistry | Disease Models, Animal | Protein Structure, Tertiary | Amino Acid Sequence | Nerve Tissue Proteins - antagonists & inhibitors | Neuroprotective Agents - chemistry | Risperidone - pharmacology | Mice, Transgenic | Risperidone - chemistry | Oligopeptides - metabolism | Cognition - drug effects | Nerve Tissue Proteins - genetics | Molecular Dynamics Simulation | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Phenotype | Animals | Protein Binding | Doxycycline - pharmacology | Risperidone - metabolism | Mice | Oligopeptides - pharmacology | Neuroprotection | Mental disorders | Cognitive ability | Schizophrenia | Amino acid sequence | Pattern recognition | Gene expression | Mimicry | ADNP protein | Proteins | Foxp2 protein | Plasticity (synaptic) | Language | Doxycycline | Forkhead protein | Anxiety | Risperidone | Bioinformatics | Disc1 protein | Index Medicus
Journal Article
Biological Psychiatry, ISSN 0006-3223, 02/2019, Volume 85, Issue 4, pp. 305 - 316
Disrupted in schizophrenia 1 (DISC1) has been implicated in a number of psychiatric diseases along with neurodevelopmental phenotypes such as the proliferation... 
Schizophrenia | CRISPR | DISC1 | Neurodevelopmental disorders | Proteomics | Neural development | VARIANTS | PSYCHIATRY | PROGENITOR PROLIFERATION | NEUROSCIENCES | DISRUPTED-IN-SCHIZOPHRENIA-1 | INTELLECTUAL DISABILITY | MUTATION | GENETIC RISK-FACTOR | MENTAL-ILLNESS | BRAIN
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 2003, Volume 8, Issue 7, pp. 685 - 694
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