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The Journal of Cell Biology, ISSN 0021-9525, 3/2004, Volume 164, Issue 5, pp. 769 - 779
All ligands of the epidermal growth factor receptor (EGFR), which has important roles in development and disease, are released from the membrane by proteases.... 
EGF receptor | Growth factor signaling | EGF receptor ligands | ADAMs | Ectodomain shedding | CELLS | ectodomain shedding | HB-EGF | TACE | PROTEIN-COUPLED RECEPTORS | ALPHA-CONVERTING-ENZYME | growth factor signaling | MICE LACKING | FAMILY | CELL BIOLOGY | EPIDERMAL-GROWTH-FACTOR | TGF-ALPHA | METALLOPROTEASE-DISINTEGRIN | ADAM17 Protein | Metalloendopeptidases - genetics | Phenylalanine - analogs & derivatives | Glycoproteins - metabolism | Metalloendopeptidases - metabolism | Thiophenes - metabolism | Epiregulin | Amphiregulin | Disintegrins - genetics | ADAM12 Protein | Intercellular Signaling Peptides and Proteins - metabolism | Receptor, Epidermal Growth Factor - metabolism | EGF Family of Proteins | Embryo, Mammalian - anatomy & histology | Aspartic Acid Endopeptidases | Amyloid Precursor Protein Secretases | Muscle Proteins - metabolism | Membrane Proteins - metabolism | Transforming Growth Factor alpha - metabolism | Fibroblasts - metabolism | Tetradecanoylphorbol Acetate - metabolism | Protein Structure, Tertiary | Endopeptidases - metabolism | Phenylalanine - metabolism | Disintegrins - metabolism | Membrane Proteins - genetics | Cells, Cultured | Epidermal Growth Factor - metabolism | Genotype | Protease Inhibitors - metabolism | ADAM Proteins | Mice, Knockout | Muscle Proteins - genetics | Heparin-binding EGF-like Growth Factor | Animals | Endopeptidases - genetics | Betacellulin | Ligands | Fibroblasts - cytology | Mice | Cytology | Research | Proteins | Enzymes | Cellular biology | Rodents | Index Medicus | EGF receptor; EGF receptor ligands; ADAMs; ectodomain shedding; growth factor signaling
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 02/2012, Volume 302, Issue 4, pp. C644 - C651
Borst O, Abed M, Alesutan I, Towhid ST, Qadri SM, Foller M, Gawaz M, Lang F. Dynamic adhesion of eryptotic erythrocytes to endothelial cells via... 
Scavenger receptor binding phosphatidylserine and oxidized low-density lipoprotein | Eryptosis | Phosphatidylserine | Endothelium | endothelium | CHEMOKINE LIGAND-16 | PHYSIOLOGY | CATION CONDUCTANCE | SR-PSOX | INFECTED ERYTHROCYTES | CELL BIOLOGY | phosphatidylserine | eryptosis | SCAVENGER RECEPTOR | DISINTEGRIN | scavenger receptor binding phosphatidylserine and oxidized low-density lipoprotein | RED-BLOOD-CELLS | PHOSPHATIDYLSERINE EXPOSURE | SUICIDAL DEATH | EXPRESSION | Endothelium, Vascular - cytology | RNA, Small Interfering - genetics | Antibodies - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Calcium - metabolism | Humans | Receptors, Scavenger - antagonists & inhibitors | Human Umbilical Vein Endothelial Cells - cytology | Erythrocytes - cytology | Cell Membrane - metabolism | Receptors, Scavenger - metabolism | Chemokines, CXC - antagonists & inhibitors | Chemokine CXCL16 | Rheology | Phosphatidylserines - metabolism | Gene Silencing | Cell Size | Chemokines, CXC - genetics | Cell Adhesion | Glucose - deficiency | Annexin A5 - metabolism | Cell Death - physiology | Receptors, Scavenger - genetics | Endothelium, Vascular - metabolism | Chemokines, CXC - metabolism | Erythrocytes - metabolism | Ionomycin - metabolism | Calcium Ionophores - metabolism | Cytosol - metabolism | Erythrocyte Count | RNA, Small Interfering - metabolism | Research | Properties | Cell adhesion | Erythrocytes | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/2003, Volume 22, Issue 10, pp. 2411 - 2421
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2005, Volume 25, Issue 12, pp. 3032 - 3040
Epidemiological studies suggest that increased intake of the omega-3 ( n-3) polyunsaturated fatty acid (PUFA) docosahexaenoic acid (DHA) is associated with... 
Polyunsaturated fatty acid | APP | DHA | Alzheimer | Secretase | OXIDATIVE STRESS | LIPID-PEROXIDATION | secretase | N-3 FATTY-ACIDS | NEUROSCIENCES | DISINTEGRIN METALLOPROTEASE | A beta | DOCOSAPENTAENOIC ACID | PLAQUE-FORMATION | RETINOID-X-RECEPTOR | PRECURSOR PROTEIN | polyunsaturated fatty acid | ALPHA-SECRETASE CLEAVAGE | TRANSGENIC MICE | Enzyme-Linked Immunosorbent Assay - methods | Prealbumin - genetics | Central Nervous System - metabolism | Male | Statistics as Topic | RNA, Messenger - metabolism | Apolipoproteins E - metabolism | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Alzheimer Disease - diet therapy | Amyloid - metabolism | Aspartic Acid Endopeptidases | Reverse Transcriptase Polymerase Chain Reaction - methods | Amyloid Precursor Protein Secretases | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Fatty Acids - metabolism | Disease Models, Animal | Endopeptidases - metabolism | Blotting, Western - methods | Peptide Fragments - metabolism | Plaque, Amyloid - pathology | Administration, Oral | Mice, Transgenic | Docosahexaenoic Acids - administration & dosage | Immunohistochemistry - methods | Docosahexaenoic Acids - pharmacology | Amyloid beta-Protein Precursor - genetics | Animals | Endopeptidases - genetics | Analysis of Variance | Prealbumin - metabolism | Apolipoproteins E - genetics | Alzheimer Disease - metabolism | Central Nervous System - drug effects | Dietary Fats, Unsaturated - administration & dosage | Mice | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2004, Volume 10, Issue 24, pp. 8363 - 8370
Purpose and Experimental Design: We have been investigating genes involved in pulmonary carcinogenesis by examining gene expression profiles of non–small-cell... 
ONCOLOGY | DISINTEGRIN | TISSUE MICROARRAYS | CLASSIFICATION | PROTEINS | IDENTIFICATION | EXPRESSION | CARCINOMA | CHEMOTHERAPY | FAMILY | METALLOPROTEASES | NIH 3T3 Cells | Adenocarcinoma - pathology | Carcinoma, Small Cell - genetics | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Metalloendopeptidases - metabolism | RNA, Messenger - metabolism | Antigens, CD - genetics | Immunoenzyme Techniques | Antigens, CD - metabolism | Carcinoembryonic Antigen - metabolism | Adenocarcinoma - metabolism | Aged, 80 and over | Biomarkers, Tumor - metabolism | Membrane Proteins - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Proteoglycans - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Mice | Carcinoma, Small Cell - pathology | COS Cells | Cell Movement | Metalloendopeptidases - genetics | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Cercopithecus aethiops | Lung Neoplasms - pathology | Serology | Case-Control Studies | Transfection | Adult | Female | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Lung - metabolism | Membrane Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Carcinoma, Large Cell - metabolism | Enzyme-Linked Immunosorbent Assay | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Small Cell - metabolism | Neoplasm Invasiveness | RNA, Messenger - genetics | ADAM Proteins | Collagen - metabolism | Animals | Aged | Laminin - metabolism | Drug Combinations | Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 06/2012, Volume 104, Issue 12, pp. 906 - 922
Background A disintegrin and metalloproteinase 28 (ADAM28) is implicated in tumor growth and metastasis in human breast and non-small cell lung carcinomas. We... 
VONWILLEBRAND-FACTOR | A1 DOMAIN | ANGIOGENESIS | ONCOLOGY | DISINTEGRIN | FACTOR BINDING PROTEIN-3 | TUMOR-CELLS | PROLIFERATION | INTEGRIN ALPHA(V)BETA | GROWTH-FACTOR | METALLOPROTEINASES | Immunohistochemistry | Neoplasms - metabolism | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Immunoblotting | Lung Neoplasms - pathology | Transplantation, Heterologous | Kidney Neoplasms - metabolism | von Willebrand Factor - genetics | Luminescent Measurements | Breast Neoplasms - metabolism | Gene Knockdown Techniques | Neoplasms, Experimental - pathology | Liver Neoplasms - pathology | von Willebrand Factor - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Renal Cell - pathology | Carcinoma, Non-Small-Cell Lung - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Gene Expression Regulation, Enzymologic | Carcinoma, Renal Cell - metabolism | Two-Hybrid System Techniques | ADAM Proteins - metabolism | Animals | Breast Neoplasms - pathology | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Neoplasms, Experimental - metabolism | ADAM Proteins - genetics | Neoplasms - pathology | RNA, Small Interfering - administration & dosage | Apoptosis | Carcinoma, Hepatocellular - metabolism | RNA, Small Interfering - metabolism | Physiological aspects | Breast cancer | Metastasis | Research | Lung cancer, Non-small cell | Von Willebrand factor | Enzymes | Oncology | Glycoproteins | Ribozymes | Cells | Index Medicus
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2015, Volume 185, Issue 4, pp. 1145 - 1155
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 01/2017, Volume 1864, Issue 1, pp. 217 - 230
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 10/2004, Volume 31, Issue 4, pp. 413 - 422
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 19, pp. 6080 - 6085
Journal Article
Journal Article
Allergy, ISSN 0105-4538, 01/2018, Volume 73, Issue 1, pp. 125 - 136
BackgroundAllergy and allergic asthma are significant health burdens in developed countries and are increasing in prevalence. Dendritic cells (DCs) initiate... 
animal models | asthma | dendritic cells | IgE | ACTIVATION | OX40 LIGAND | INDUCTION | IMMUNOLOGY | B-CELL | ALLERGY | DISINTEGRIN | INFLAMMATION | IN-VIVO | ARCHITECTURE | DIFFERENTIATION | EXPRESSION | Amyloid Precursor Protein Secretases - genetics | Immunoglobulin G - blood | ADAM10 Protein - genetics | Dendritic Cells - immunology | ADAM10 Protein - metabolism | Hypersensitivity - immunology | Th2 Cells - immunology | Th1 Cells - immunology | Th1 Cells - metabolism | Immunoglobulin E - immunology | Hypersensitivity - metabolism | Th17 Cells - metabolism | Immunoglobulin G - immunology | Kruppel-Like Transcription Factors - metabolism | Anaphylaxis - immunology | Membrane Proteins - metabolism | Interleukin-6 - metabolism | Dendritic Cells - metabolism | Disease Models, Animal | Gene Expression | Interleukin-6 - genetics | Signal Transduction | Membrane Proteins - genetics | Receptor, Notch1 - metabolism | Th2 Cells - metabolism | Mice, Knockout | Amyloid Precursor Protein Secretases - metabolism | Animals | Biomarkers | Th17 Cells - immunology | Mice | Anaphylaxis - metabolism | Receptor, Notch1 - genetics | Kruppel-Like Transcription Factors - genetics | Pyroglyphidae - immunology | Immunoglobulin E | Dendritic cells | Analysis | Asthma | Developed countries | Allergens | Animal models | Immune response | Cytokines | Lung | Hypersensitivity | Helper cells | House dust | Intracellular signalling | Lymphocytes T | Immunity | Substrates | Respiratory tract | Anaphylaxis | Respiratory tract diseases | Notch protein | Citrobacter | Index Medicus
Journal Article