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American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 06/2009, Volume 296, Issue 6, pp. 1318 - 1323
Journal Article
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, ISSN 1871-5206, 2018, Volume 18, Issue 11, pp. 1599 - 1605
Background: Thioredoxin reductase (E.C 1.6.4.5.; TrxR) is a widely distributed flavoprotein that catalyzes the NAI)PH-dependent reduction of thioredoxin (Trx)... 
SECONDARY METABOLITES | MAMMALIAN THIOREDOXIN | CHEMISTRY, MEDICINAL | LIVER THIOREDOXIN | inhibition | CELL-LINES | Thioredoxin reductase | mitochondrial TrxR.f | MAJOR METABOLITES | lichen acid | HYPOGYMNIA-PHYSODES | ONCOLOGY | ANTIOXIDANT | rat lung | PURIFICATION | USNIC ACID | cancer | DIFFRACTAIC ACID | Depsides - chemical synthesis | Anisoles - pharmacology | Antineoplastic Agents - chemical synthesis | Furans - pharmacology | Lichens - chemistry | Male | Doxorubicin - chemistry | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Lactones - pharmacology | Depsides - pharmacology | Lung - enzymology | Phenylacetates - chemistry | Salicylates - chemistry | Dose-Response Relationship, Drug | Salicylates - pharmacology | Cisplatin - chemistry | Hydroxybenzoates - pharmacology | Lactones - chemical synthesis | Thioredoxin-Disulfide Reductase - metabolism | Furans - chemistry | Hydroxybenzoates - chemical synthesis | Phenylacetates - chemical synthesis | Enzyme Inhibitors - chemistry | Hydroxybenzoates - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Lactones - chemistry | Enzyme Inhibitors - pharmacology | Rats | Thioredoxin-Disulfide Reductase - isolation & purification | Depsides - chemistry | Anisoles - chemistry | Mitochondria - metabolism | Cisplatin - pharmacology | Mitochondria - drug effects | Salicylates - chemical synthesis | Antineoplastic Agents - chemistry | Rats, Sprague-Dawley | Animals | Thioredoxin-Disulfide Reductase - antagonists & inhibitors | Anisoles - chemical synthesis | Furans - chemical synthesis | Doxorubicin - pharmacology | Phenylacetates - pharmacology
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 06/2012, Volume 90, Issue 6, pp. 1218 - 1229
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2005, Volume 39, Issue 5, pp. 696 - 703
Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 2011, Volume 11, Issue 3, pp. 249 - 253
Garlic and garlic-derived compounds reduce the development of mammary cancer in animals and suppress the growth of human breast cancer cells in culture.... 
7,12-dimethylbenz[α]anthracene (DMBA) | Breast | Garlic | N-methyl-Nnitrosourea (MNU) | Selenium | Mammary | Diallyl disulfide (DADS) | Apoptosis | DNA-ADDUCTS | N-methyl-N-nitrosourea (MNU) | CHEMISTRY, MEDICINAL | PREVENTION | RATS | apoptosis | 7,12-dimethylbenz[alpha] anthracene (DMBA) | CELL-PROLIFERATION | CHEMOPREVENTION | MAMMARY-CANCER | S-ALLYLMERCAPTOCYSTEINE | ORGANOSULFUR COMPOUNDS | mammary | selenium | ONCOLOGY | breast | DIALLYL DISULFIDE | diallyl disulfide (DADS) | Plant Extracts - chemistry | DNA Adducts - drug effects | Apoptosis - drug effects | Plant Extracts - pharmacology | Selenium - pharmacology | Humans | Sulfinic Acids - pharmacology | Garlic - chemistry | Organoselenium Compounds - pharmacology | Linoleic Acid - adverse effects | Eicosapentaenoic Acid - pharmacology | Disulfides - pharmacology | Female | Antineoplastic Agents - pharmacology | Anticarcinogenic Agents - pharmacology | Solubility | Rats | Allyl Compounds - pharmacology | Antineoplastic Agents - chemistry | Breast Neoplasms - drug therapy | Rats, Sprague-Dawley | Breast Neoplasms - prevention & control | Drug Synergism | Reactive Oxygen Species - antagonists & inhibitors | Animals | Anticarcinogenic Agents - chemistry | Drug Antagonism | Breast Neoplasms - pathology | Cell Line, Tumor | Cell Cycle - drug effects | Selenium compounds | Cell culture | Enzymes | Reactive oxygen species | Breast cancer | Carcinogenesis | Synergism | diallyl disulfide | Linoleic acid | Carcinogens | Side effects | DNA adducts | Eicosapentaenoic acid
Journal Article
Nature Biotechnology, ISSN 1087-0156, 08/2008, Volume 26, Issue 8, pp. 925 - 932
Journal Article
Journal Article
Journal Article