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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2013, Volume 110, Issue 29, pp. 12108 - 12113
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2013, Volume 23, Issue 24, pp. 6682 - 6687
Journal Article
Molecules, ISSN 1420-3049, 10/2018, Volume 23, Issue 10, p. 2602
The acute activation of kappa opioid receptors (KOPr) produces antinociceptive and anti-cocaine effects, however, their side-effects have limited further... 
Drug abuse | Locomotion | Conditioned taste aversion | Forced swim test | Kappa opioid | Addiction | Behavioral sensitization | Salvinorin A | Depression | Behavioral pharmacology | LONG-TERM | EXTRACELLULAR DOPAMINE | CONDITIONED PLACE AVERSION | behavioral sensitization | NEOCLERODANE DITERPENES | PLANT-DERIVED HALLUCINOGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | locomotion | addiction | A ANALOGS | conditioned taste aversion | ELEVATED PLUS-MAZE | NALFURAFINE HYDROCHLORIDE | CHEMISTRY, MULTIDISCIPLINARY | kappa opioid | behavioral pharmacology | NUCLEUS-ACCUMBENS | drug abuse | depression | INCENTIVE-SENSITIZATION | forced swim test | Learning - drug effects | Motor Activity - drug effects | Male | Anxiety - drug therapy | Pain - metabolism | Diterpenes, Clerodane - chemistry | Cocaine-Related Disorders - metabolism | Pain - drug therapy | Nociception - drug effects | Pain - etiology | Behavior, Animal - drug effects | Cocaine - adverse effects | Anxiety - metabolism | Diterpenes - chemistry | Diterpenes - pharmacology | Cocaine-Related Disorders - psychology | Receptors, Opioid, kappa - agonists | Rats | Diterpenes, Clerodane - adverse effects | Mesylates - adverse effects | Mesylates - chemistry | Animals | Recognition (Psychology) - drug effects | Mesylates - pharmacology | Diterpenes, Clerodane - pharmacology | Cocaine-Related Disorders - drug therapy | Mice | Diterpenes - adverse effects
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2018, Volume 63, Issue 2, pp. 705 - 723
Soluble amyloid-beta (A beta) oligomers have been recognized as early neurotoxic intermediates with a key role in the synaptic dysfunction observed in... 
ferruginol | diterpenes | Amyloid-β | junicedric acid | neuroprotection | jatrophone | PROTEIN-KINASE-C | SIGNALING PATHWAYS | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | COGNITIVE IMPAIRMENT | NEUROSCIENCES | MOUSE MODELS | SPATIAL MEMORY | LONG-TERM POTENTIATION | SOLUBLE OLIGOMERS | Amyloid-beta | IMPAIR SYNAPTIC PLASTICITY | Neurons - pathology | Synaptic Transmission - physiology | Apoptosis - drug effects | Calcium - metabolism | Humans | Male | Hippocampus - drug effects | Synapses - pathology | Alzheimer Disease - pathology | Diterpene Alkaloids - chemistry | Neuroprotective Agents - pharmacology | Synapses - metabolism | Long-Term Potentiation - drug effects | Amyloid beta-Peptides - metabolism | Long-Term Potentiation - physiology | Synaptic Transmission - drug effects | Neurons - metabolism | Neurons - drug effects | Diterpenes - chemistry | Diterpenes - pharmacology | Synapses - drug effects | Peptide Fragments - metabolism | Neuroprotective Agents - chemistry | Tissue Culture Techniques | Mice, Inbred C57BL | Cells, Cultured | Alzheimer Disease - drug therapy | Diterpenes, Abietane - chemistry | Hippocampus - pathology | Hippocampus - metabolism | Diterpenes, Abietane - pharmacology | Animals | Alzheimer Disease - metabolism | Apoptosis - physiology | Diterpene Alkaloids - pharmacology | Potentiation | Neuroprotection | Protein kinase C | Calcium | Glutamic acid receptors (ionotropic) | Spatial discrimination | Plants (organisms) | Kinases | Proteins | Oligomers | Memory tasks | Signal transduction | Neurotoxicity | Synaptic transmission | Rodents | Calcium-binding protein | Amyloid | Alzheimer's disease | Calmodulin | Medicinal plants | Calcium (intracellular) | Neurons | Long-term potentiation | Spatial analysis | N-Methyl-D-aspartic acid receptors | Biological activity | Intermediates | Acids | Diterpenes | Intracellular | Postsynaptic density proteins | Hippocampus | Apoptosis | Ca2+/calmodulin-dependent protein kinase II
Journal Article
Phytochemistry, ISSN 0031-9422, 02/2015, Volume 110, pp. 120 - 132
Journal Article