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ACS Nano, ISSN 1936-0851, 2014, Volume 8, Issue 8, pp. 8027 - 8039
Journal Article
FEBS Journal, ISSN 1742-464X, 12/2015, Volume 282, Issue 24, pp. 4747 - 4765
Renal cell carcinoma ( RCC ) is resistant to traditional cancer therapies, and metastatic RCC (mRCC) is incurable. The shortcomings in current therapeutic... 
apoptosis | triptolide | renal cell carcinoma | TRAIL | death receptor | HEAT-SHOCK-PROTEIN-70 INHIBITS APOPTOSIS | DENDRITIC CELLS | (TRAIL)-INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTI-DR5 ANTIBODY THERAPY | HEAT-SHOCK PROTEINS | TUMOR-NECROSIS-FACTOR | APOPTOSIS-INDUCING LIGAND | IN-VIVO | NF-KAPPA-B | PANCREATIC-CANCER CELLS | Recombinant Proteins - therapeutic use | Neoplasm Transplantation | Antineoplastic Combined Chemotherapy Protocols - chemistry | Apoptosis - drug effects | Receptors, TNF-Related Apoptosis-Inducing Ligand - agonists | Humans | Organophosphates - therapeutic use | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Kidney Neoplasms - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Epoxy Compounds - pharmacology | TNF-Related Apoptosis-Inducing Ligand - pharmacology | TNF-Related Apoptosis-Inducing Ligand - agonists | Female | Antineoplastic Agents - pharmacology | Antineoplastic Agents, Phytogenic - therapeutic use | Carcinoma, Renal Cell - drug therapy | Antibodies, Monoclonal - chemistry | Diterpenes - pharmacology | Epoxy Compounds - therapeutic use | Diterpenes - therapeutic use | Phenanthrenes - therapeutic use | Specific Pathogen-Free Organisms | Carcinoma, Renal Cell - pathology | Antibodies, Monoclonal - pharmacology | Recombinant Proteins - chemistry | Recombinant Proteins - pharmacology | Antineoplastic Agents - chemistry | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Drug Synergism | Organophosphates - pharmacology | Carcinoma, Renal Cell - metabolism | Phenanthrenes - pharmacology | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Mice, Inbred BALB C | Prodrugs - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Kidney Neoplasms - drug therapy | Prodrugs - pharmacology | TNF-Related Apoptosis-Inducing Ligand - genetics | Heat shock proteins | Carcinoma, Renal cell | Rodents | Tumors | Apoptosis | Index Medicus
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 08/2017, Volume 37, Issue 15
Journal Article
Pain, ISSN 0304-3959, 12/2018, Volume 159, Issue 12, pp. 2538 - 2546
Journal Article
Journal of Photochemistry & Photobiology, B: Biology, ISSN 1011-1344, 07/2014, Volume 136, pp. 12 - 18
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2017, Volume 485, Issue 1, pp. 69 - 75
Triptolide is the predominant active component of the Chinese herb Tripterygium wilfordii Hook F (TwHF) that has been widely used to treat several chronic... 
Hypertension | NLRP3 | Inflammation | Myocardial remodeling | Triptolide | RHEUMATOID-ARTHRITIS | FIBROSIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOMYOPATHY | INJURY | HEART | CARDIAC FIBROBLASTS | BIOPHYSICS | PATHWAY | DISEASE | DYSFUNCTION | Myocardium - immunology | Heart Ventricles - immunology | Male | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Phenanthrenes - chemistry | Hypertrophy, Left Ventricular - genetics | Tripterygium - chemistry | Hypertrophy, Left Ventricular - pathology | Myocardium - metabolism | Anti-Inflammatory Agents - therapeutic use | Hypertrophy, Left Ventricular - drug therapy | Drugs, Chinese Herbal - therapeutic use | Heart Ventricles - pathology | Diterpenes - chemistry | Epoxy Compounds - therapeutic use | Diterpenes - therapeutic use | Phenanthrenes - therapeutic use | Immunity, Innate - drug effects | Mice, Inbred C57BL | Myocardium - pathology | Down-Regulation - drug effects | Inflammasomes - genetics | Hypertrophy, Left Ventricular - immunology | Animals | Anti-Inflammatory Agents - chemistry | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Drugs, Chinese Herbal - chemistry | Epoxy Compounds - chemistry | Inflammasomes - immunology | Fibrosis | Heart Ventricles - metabolism | Mice | Ventricular Remodeling - drug effects | Heart Ventricles - drug effects | Heart | Cardiology | Transforming growth factors | Heart diseases | MICE | INHIBITION | 60 APPLIED LIFE SCIENCES | INTRAPERITONEAL INJECTION | INFLAMMATION
Journal Article