X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (644) 644
Publication (57) 57
Newsletter (24) 24
Book Review (14) 14
Newspaper Article (12) 12
Book Chapter (7) 7
Conference Proceeding (5) 5
Magazine Article (2) 2
Trade Publication Article (1) 1
Transcript (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
dofetilide (594) 594
humans (280) 280
cardiac & cardiovascular systems (232) 232
animals (223) 223
pharmacology & pharmacy (219) 219
male (177) 177
female (160) 160
index medicus (155) 155
anti-arrhythmia agents - pharmacology (134) 134
atrial fibrillation (122) 122
sulfonamides - pharmacology (115) 115
phenethylamines - pharmacology (113) 113
arrhythmia (105) 105
anti-arrhythmia agents - therapeutic use (101) 101
electrocardiography (96) 96
action potentials - drug effects (91) 91
middle aged (85) 85
dose-response relationship, drug (84) 84
atrial fibrillation - drug therapy (82) 82
block (77) 77
aged (73) 73
amiodarone (72) 72
efficacy (71) 71
heart (70) 70
anti-arrhythmia agents - adverse effects (66) 66
patch-clamp techniques (66) 66
heart rate - drug effects (61) 61
potassium channels (60) 60
flutter (59) 59
iii antiarrhythmic agent (58) 58
in vitro techniques (58) 58
analysis (57) 57
herg (57) 57
potassium channel blockers - pharmacology (57) 57
electrophysiology (56) 56
erg1 potassium channel (56) 56
prolongation (56) 56
sotalol (56) 56
anti-arrhythmia agents - administration & dosage (55) 55
atrial-fibrillation (55) 55
drugs (54) 54
guinea pigs (53) 53
sulfonamides - therapeutic use (53) 53
phenethylamines - therapeutic use (52) 52
treatment outcome (51) 51
dogs (50) 50
potassium channel (50) 50
repolarization (50) 50
d-sotalol (49) 49
potassium channel blockers (49) 49
heart - drug effects (48) 48
long qt syndrome (48) 48
qt interval (48) 48
adult (47) 47
anti-arrhythmia drugs (47) 47
atrial fibrillation - physiopathology (46) 46
phenethylamines - administration & dosage (46) 46
sulfonamides - administration & dosage (46) 46
i-kr (45) 45
left-ventricular dysfunction (44) 44
research (44) 44
sulfonamides - adverse effects (43) 43
toxicology (43) 43
arrhythmias (42) 42
ether-a-go-go potassium channels (42) 42
myocytes (42) 42
phenethylamines - adverse effects (42) 42
guinea-pig (41) 41
rectifier k+-current (41) 41
safety (41) 41
torsades de pointes (41) 41
mortality (40) 40
potassium channels, voltage-gated (40) 40
uk-68,798 (40) 40
action-potential duration (39) 39
rabbits (39) 39
drug therapy (38) 38
molecular determinants (38) 38
risk factors (38) 38
sinus rhythm (36) 36
torsade-de-pointes (36) 36
electrocardiogram (35) 35
torsades de pointes - chemically induced (35) 35
cardiac arrhythmia (34) 34
time factors (34) 34
torsades-de-pointes (34) 34
antiarrhythmic agents (33) 33
fibrillation (33) 33
potassium (33) 33
long qt syndrome - chemically induced (32) 32
potassium channels - drug effects (32) 32
care and treatment (31) 31
cation transport proteins (31) 31
electrocardiography - drug effects (31) 31
cell line (30) 30
congestive-heart-failure (30) 30
disease models, animal (30) 30
heart conduction system - drug effects (30) 30
torsade de pointes (30) 30
dofetilide block (29) 29
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0201059
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 08/2019, Volume 172, pp. 183 - 188
A novel method using UPLC with tandem mass-spectrometric detection (UPLC-MS/MS) with positive electrospray ionization was developed for the detection of the... 
UPLC-MS/MS | Dofetilide | Pharmacokinetics | Mouse plasma | Mouse urine
Journal Article
PLOS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12
Background Prolongation of the heart rate corrected QT (QTc) interval is a sensitive marker of torsade de pointes risk; however it is not specific as QTc... 
HEART | WAVES | DOFETILIDE | CELLULAR-BASIS | RECORDINGS | MULTIDISCIPLINARY SCIENCES | RANOLAZINE | BLOCK | ECG | LONG QT SYNDROME | REPOLARIZATION
Journal Article
Therapeutic Advances in Drug Safety, ISSN 2042-0986, 7/2018, Volume 9, Issue 7, pp. 367 - 372
An 84-year-old woman presented to her primary care physician with an unexplained 4-month history of weight and appetite loss after initiation of dofetilide 125... 
aged | dofetilide | anorexia | antiarrhythmia agents | Case Report
Journal Article
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, ISSN 1074-2484, 01/2019, Volume 24, Issue 1, pp. 3 - 10
Dofetilide is a class III antiarrhythmic agent approved by the Food and Drug Administration for the conversion of atrial fibrillation and atrial flutter and... 
ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | RHYTHM CONTROL | ACUTE TERMINATION | EFFICACY | SAFETY | FLUTTER | atrial flutter | dofetilide | PERSISTENT ATRIAL-FIBRILLATION | III ANTIARRHYTHMIC AGENT | ACUTE CONVERSION | atrial fibrillation | ORAL DOFETILIDE | PHARMACOLOGY & PHARMACY
Journal Article
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 08/2019, Volume 176, Issue 15, pp. 2708 - 2723
Background and Purpose The ether-a-go-go (Eag) K-v superfamily comprises closely related K(v)10, K(v)11, and K(v)12 subunits. K(v)11.1 (termed hERG in humans)... 
INACTIVATION | DOFETILIDE BLOCK | HERG | POTASSIUM CHANNELS | CARDIAC-ARRHYTHMIA | FORCE-FIELD | PHARMACOLOGY & PHARMACY | HIGH-AFFINITY BLOCK | MOLECULAR DETERMINANTS | EAG | K+ CHANNEL
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 08/2019, Volume 96, Issue 2, pp. 259 - 271
Abnormal cardiac electrical activity is a common side effect caused by unintended block of the promiscuous drug target human ether-a-go-go-related gene... 
INACTIVATION | ION SELECTIVITY | HUMAN INWARD RECTIFIER | DRUG-BINDING | STRUCTURAL BASIS | DOFETILIDE BINDING | FORCE-FIELD | PHARMACOLOGY & PHARMACY | MOLECULAR DETERMINANTS | LONG-QT SYNDROME | K+ CHANNELS
Journal Article
Pacing and Clinical Electrophysiology, ISSN 0147-8389, 04/2018, Volume 41, Issue 4, pp. 396 - 401
Journal Article
Circulation: Arrhythmia and Electrophysiology, ISSN 1941-3149, 10/2017, Volume 10, Issue 10
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 06/2019, Volume 10
Background and Purpose: Prolongation of cardiac action potentials is considered antiarrhythmic in the atria but can be proarrhythmic in ventricles if the... 
Atrial fibrillation | Dofetilide | Ondansetron | AP14145 | QT prolongation | dofetilide | ondansetron | arrhythmia (heart rhythm disorders)
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.