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Journal of Biological Chemistry, ISSN 0021-9258, 03/2012, Volume 287, Issue 10, pp. 7556 - 7572
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 07/2015, Volume 74, Issue 7, pp. 1432 - 1440
ObjectivesMammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific... 
RAPAMYCIN | LIFE-SPAN | MOUSE | KINASE | GROWTH | ACTIVATED-RECEPTOR-GAMMA | AMPK | ULK1 | MODEL | RHEUMATOLOGY | AMP-Activated Protein Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Male | Autophagy - physiology | Intracellular Signaling Peptides and Proteins - metabolism | TOR Serine-Threonine Kinases - deficiency | Autophagy-Related Protein-1 Homolog | Chondrocytes - drug effects | Cartilage, Articular - metabolism | Up-Regulation - physiology | Aged, 80 and over | Osteoarthritis - pathology | Immunosuppressive Agents - pharmacology | Intracellular Signaling Peptides and Proteins - genetics | Chondrocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Chondrocytes - pathology | Osteoarthritis - prevention & control | Mice, Inbred C57BL | Cells, Cultured | Gene Silencing | Protein-Serine-Threonine Kinases - genetics | Osteoarthritis - metabolism | Sirolimus - pharmacology | Matrix Metalloproteinase 13 - metabolism | Mice, Knockout | Cartilage, Articular - pathology | Animals | Dogs | Signal Transduction - physiology | Aged | Mice | Apoptosis - physiology | Cartilage, Articular - drug effects | Physiology, Pathological | Care and treatment | Analysis | Cellular signal transduction | Research | Gene expression | Osteoarthritis | Proteins | Studies | Phosphorylation | Genes | Rodents | Surgery | Homeostasis | Arthritis | Kinases | Autophagy | Index Medicus
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, ISSN 0193-1849, 09/2017, Volume 313, Issue 3, pp. E273 - E283
Journal Article
Circulation, ISSN 0009-7322, 11/2004, Volume 110, Issue 20, pp. 3168 - 3174
Background - Computational biology is a powerful tool for elucidating arrhythmogenic mechanisms at the cellular level, where complex interactions between ionic... 
Electrophysiology | Action potentials | Ion channels | Calcium | CARDIAC & CARDIOVASCULAR SYSTEMS | calcium | action potentials | PROTEIN-KINASE | CA2+ RELEASE | SARCOPLASMIC-RETICULUM | ENDOCARDIAL MYOCYTES | ion channels | EPICARDIAL BORDER ZONE | HEART-CELLS | PHOSPHOLAMBAN PHOSPHORYLATION | electrophysiology | RYANODINE RECEPTORS | PERIPHERAL VASCULAR DISEASE | OUTWARD CURRENT | LOCAL-CONTROL | HEMATOLOGY | Potassium - metabolism | Heart Ventricles - cytology | Calcium - metabolism | Calcium Signaling - physiology | Ryanodine Receptor Calcium Release Channel - metabolism | Sodium - metabolism | Action Potentials | Myocytes, Cardiac - enzymology | Pericardium - physiology | Potassium Channels, Voltage-Gated - metabolism | Sodium-Calcium Exchanger - metabolism | Chlorides - metabolism | Computer Simulation | Heart Conduction System - physiology | Sodium Channels - metabolism | Heart Rate - physiology | Ion Transport | Sarcoplasmic Reticulum - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 | 4-Aminopyridine - pharmacology | Sodium Chloride Symporters | Isoenzymes - physiology | Calcium-Calmodulin-Dependent Protein Kinases - physiology | Models, Cardiovascular | Computational Biology | Cardiac Pacing, Artificial | Delayed Rectifier Potassium Channels | Symporters - metabolism | Animals | Myocytes, Cardiac - physiology | Dogs | Calcium Channels, L-Type - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Cell Science, ISSN 0021-9533, 04/2004, Volume 117, Issue 9, pp. 1675 - 1685
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 01/2017, Volume 21, Issue 1, pp. 23 - 34
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 03/2016, Volume 524, Issue 4, pp. 874 - 895
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2009, Volume 11, Issue 10, pp. 1233 - 1240
Journal Article