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1. Full Text Distinct Dopamine D₂ Receptor Antagonists Differentially Impact D₂ Receptor Oligomerization
by Wouters, Elise and Marín, Adrián Ricarte and Dalton, James Andrew Rupert and Giraldo, Jesús and Stove, Christophe
International journal of molecular sciences, ISSN 1422-0067, 04/2019, Volume 20, Issue 7, p. 1686
Biotechnology | Bioluminescence | Oligomerization | Dopamine | G protein-coupled receptors | Peptides | Mental disorders | Schizophrenia | Fluorescence | Proteins | Interfaces | Lifetime | Microscopy | Isoforms | Cell lines | Comparative studies | Ligands | Physiology | Resonance | Dimers | Fluorescence resonance energy transfer | Dopamine D2 receptors | Energy transfer | G protein-coupled receptor (GPCR) | dimerization | protein complementation assay | NanoLuc binary technology (NanoBiT) | oligomerization | dopamine D2 receptor
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2. Full Text Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO
by Girgis, Ragy R and Slifstein, Mark and D’Souza, Deepak and Lee, Yih and Periclou, Antonia and Ghahramani, Parviz and Laszlovszky, István and Durgam, Suresh and Adham, Nika and Nabulsi, Nabeel and Huang, Yiyun and Carson, Richard E and Kiss, Béla and Kapás, Margit and Abi-Dargham, Anissa and Rakhit, Ashok
Psychopharmacology, ISSN 0033-3158, 10/2016, Volume 233, Issue 19, pp. 3503 - 3512
Neurosciences | Biomedicine | Cariprazine | Dopamine D 3 receptor | Occupancy | Schizophrenia | Antipsychotic | Pharmacology/Toxicology | Psychiatry | [ 11 C]-(+)-PHNO | Dopamine D 2 receptor | Positron emission tomography | C]-(+)-PHNO | receptor | Dopamine D | Brain - diagnostic imaging | Oxazines | Schizophrenia - metabolism | Humans | Middle Aged | Receptors, Dopamine D3 - metabolism | Male | Piperazines - metabolism | Positron-Emission Tomography | Receptors, Dopamine D2 - metabolism | Dopamine Agonists | Brain - metabolism | Young Adult | Antipsychotic Agents - therapeutic use | Adult | Female | Radiopharmaceuticals | Dopamine - metabolism | Drug Partial Agonism | Piperazines - therapeutic use | Schizophrenia - diagnostic imaging | Protein Binding | Antipsychotic Agents - metabolism | Schizophrenia - drug therapy | Carbon Radioisotopes | Index Medicus | Dopamine D2 receptor | Dopamine D3 receptor | [11C]-(+)-PHNO | Original Investigation
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3. Full Text The D2/3 dopamine receptor in pathological gambling: a positron emission tomography study with [11C]‐(+)‐propyl‐hexahydro‐naphtho‐oxazin and [11C]raclopride
by Boileau, Isabelle and Payer, Doris and Chugani, Bindiya and Lobo, Daniela and Behzadi, Arian and Rusjan, Pablo M and Houle, Sylvain and Wilson, Alan A and Warsh, Jerry and Kish, Stephen J and Zack, Martin
Addiction (Abingdon, England), ISSN 0965-2140, 05/2013, Volume 108, Issue 5, pp. 953 - 963
[11C]‐(+)‐PHNO | pathological gambling | positron emission tomography | dopamine | Pathological gambling | C]-(+)-PHNO | Dopamine | Positron emission tomography | Life Sciences & Biomedicine | Substance Abuse | Psychiatry | Science & Technology | Drug addiction | Psycholeptics: tranquillizer, neuroleptic | Miscellaneous | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopharmacology | Pharmacology. Drug treatments | Psychopathology. Psychiatry | Addictive behaviors | Biological and medical sciences | Medical sciences | Neuropharmacology | Brain - diagnostic imaging | Oxazines | Raclopride | Humans | Middle Aged | Receptors, Dopamine D3 - metabolism | Self Report | Male | Positron-Emission Tomography - methods | Receptors, Dopamine D2 - metabolism | Behavior, Addictive - metabolism | Case-Control Studies | Young Adult | Adult | Dopamine Antagonists | Carbon Radioisotopes | Gambling - metabolism | PET imaging | Phenols | Compulsive gambling | Tomography | Gambling | Addictions | Index Medicus
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4. Full Text A2A‐D2 receptor–receptor interaction modulates gliotransmitter release from striatal astrocyte processes
by Cervetto, Chiara and Venturini, Arianna and Passalacqua, Mario and Guidolin, Diego and Genedani, Susanna and Fuxe, Kjell and Borroto‐Esquela, Dasiel O and Cortelli, Pietro and Woods, Amina and Maura, Guido and Marcoli, Manuela and Agnati, Luigi F
Journal of neurochemistry, ISSN 0022-3042, 01/2017, Volume 140, Issue 2, pp. 268 - 279
astrocyte processes | heterodimers | glutamate | Receptor–receptor interactions | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Animals | Synaptic Transmission - physiology | Adenosine - metabolism | Male | Neostriatum - metabolism | Glutamic Acid - metabolism | Receptor, Adenosine A2A - metabolism | Receptors, Dopamine D2 - metabolism | Corpus Striatum - metabolism | Rats, Sprague-Dawley | Astrocytes - metabolism | Schizophrenia | Glutamate | Diseases | Neurochemistry | Neurotransmitters | Mental disorders | Neurological disorders | Cells | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: In vivo imaging with [18F]fallypride
by Vučcković, Marta G and Li, Quanzheng and Fisher, Beth and Nacca, Angelo and Leahy, Richard M and Walsh, John P and Mukherjee, Jogesh and Williams, Celia and Jakowec, Michael W and Petzinger, Giselle M
Movement disorders, ISSN 0885-3185, 12/2010, Volume 25, Issue 16, pp. 2777 - 2784
basal ganglia | positron emission tomography | treadmill exercise | neuroplasticity | Neuroplasticity | Treadmill exercise | Basal ganglia | Positron emission tomography | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Corpus Striatum - physiopathology | Mice, Inbred C57BL | Male | Positron-Emission Tomography | Physical Conditioning, Animal - physiology | Receptors, Dopamine D2 - metabolism | Corpus Striatum - metabolism | Blotting, Western | Animals | Analysis of Variance | Parkinson Disease, Secondary - physiopathology | Parkinson Disease, Secondary - metabolism | Pyrrolidines | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Mice | Neurons - metabolism | Benzamides | Parkinson Disease, Secondary - chemically induced | Corpus Striatum - diagnostic imaging | Parkinson Disease, Secondary - diagnostic imaging | Parkinson's disease | Dopamine | Medical imaging | Neurodegenerative diseases | Fitness equipment | Parkinsons disease | Immunoblotting | Spiny neurons | Rodents | Neostriatum | MPTP | Dopamine D2 receptors | Movement disorders | Dopamine receptors | Index Medicus
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6. Full Text In response to the letter “[11C]raclopride and extrastriatal binding to D2/3 receptors”
by Svensson, Jonas E and Schain, Martin and Plavén-Sigray, Pontus and Cervenka, Simon and Tiger, Mikael and Nord, Magdalena and Halldin, Christer and Farde, Lars and Lundberg, Johan
NeuroImage (Orlando, Fla.), ISSN 1053-8119, 02/2020, Volume 207, pp. 116371 - 116371
Neuroimaging | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Cerebellum | Brain | Raclopride | Neostriatum | Thalamus | Regions | Substantia grisea | Dopamine D2 receptors | Quetiapine | Index Medicus | Medicin och hälsovetenskap
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7. Full Text Evidence against dopamine D1/D2 receptor heteromers
by Frederick, A.L and Yano, H and Trifilieff, P and Vishwasrao, H.D and Biezonski, D and Mészáros, J and Urizar, E and Sibley, D.R and Kellendonk, C and Sonntag, K.C and Graham, D.L and Colbran, R.J and Stanwood, G.D and Javitch, J.A
Molecular psychiatry, ISSN 1359-4184, 11/2015, Volume 20, Issue 11, pp. 1373 - 1385
Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Humans | Nucleus Accumbens - metabolism | Motor Activity - drug effects | Male | Receptors, Dopamine D2 - metabolism | Corpus Striatum - metabolism | Receptors, Dopamine D1 - metabolism | Protein Multimerization - physiology | HEK293 Cells | Phosphorylation - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Protein Structure, Tertiary | Dopamine Agonists - pharmacology | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Mice, Inbred C57BL | Grooming - drug effects | Models, Molecular | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - analogs & derivatives | Receptors, Dopamine D2 - genetics | Mice, Knockout | Motor Activity - genetics | Animals | Dopamine Antagonists - pharmacology | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology | Corpus Striatum - drug effects | Luminescent Proteins - genetics | Mice | Nucleus Accumbens - drug effects | Protein Multimerization - drug effects | Luminescent Proteins - metabolism | Receptors, Dopamine D1 - genetics | Oligomers | Depression, Mental | Schizophrenia | Physiological aspects | Research | Risk factors | Dopamine receptors | Bioluminescence | Dopamine | G protein-coupled receptors | Mental disorders | Brain slice preparation | Pharmacology | Phospholipase C | Mutants | Nucleus accumbens | Proteins | Phospholipase | Signaling | Receptors | Dopamine D1 receptors | Grooming | Dimers | Receptor mechanisms | Biosensors | Localization | Dopamine D2 receptors | Energy transfer | Index Medicus | Life Sciences | BRET | D5 | striatum | Gαq | hetero-oligomer | proximity ligation assay | biased agonism | dopamine | D1 | D2
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8. Full Text On the existence of a possible A2A-D2-β- arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment
by Borroto-Escuela, Dasiel O and Romero-Fernandez, Wilber and Tarakanov, Alexander O and Ciruela, Francisco and Agnati, Luigi F and Fuxe, Kjell
Journal of molecular biology, ISSN 0022-2836, 03/2011, Volume 406, Issue 5, pp. 687 - 699
receptor-protein interaction | internalization | heteromerization | G-protein-coupled receptors | allosteric modulation | Cell Line | Humans | Protein Multimerization | Receptors, Dopamine D2 - agonists | Models, Molecular | Phenethylamines - metabolism | Adenosine A2 Receptor Agonists - metabolism | Receptor, Adenosine A2A - metabolism | Receptors, Dopamine D2 - metabolism | Arrestins - metabolism | beta-Arrestins | Adenosine - analogs & derivatives | Protein Structure, Quaternary | Adenosine - metabolism | Protein Binding | Index Medicus | Medicin och hälsovetenskap
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9. Full Text Increased Dopamine D2/D3 Receptor Binding After Recovery from Anorexia Nervosa Measured by Positron Emission Tomography and [ 11C]Raclopride
by Frank, Guido K and Bailer, Ursula F and Henry, Shannan E and Drevets, Wayne and Meltzer, Carolyn C and Price, Julie C and Mathis, Chester A and Wagner, Angela and Hoge, Jessica and Ziolko, Scott and Barbarich-Marsteller, Nicole and Weissfeld, Lisa and Kaye, Walter H
Biological psychiatry (1969), ISSN 0006-3223, 2005, Volume 58, Issue 11, pp. 908 - 912
brain imaging | [ 11C]raclopride | Anorexia nervosa | eating disorders | positron emission tomography | dopamine | Brain imaging | Dopamine | Positron emission tomography | Eating disorders | C]raclopride | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Psycholeptics: tranquillizer, neuroleptic | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopharmacology | Pharmacology. Drug treatments | Psychopathology. Psychiatry | Eating behavior disorders | Biological and medical sciences | Medical sciences | Neuropharmacology | Nucleus Accumbens - diagnostic imaging | Raclopride | Humans | Receptors, Dopamine D3 - metabolism | Anorexia - metabolism | Positron-Emission Tomography | Receptors, Dopamine D2 - metabolism | Magnetic Resonance Imaging | Algorithms | Anorexia - psychology | Anorexia - diagnostic imaging | Adult | Female | Neostriatum - diagnostic imaging | Reward | Dopamine Antagonists | Medical colleges | PET imaging | Phenols | Anxiety | Index Medicus
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