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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2007, Volume 320, Issue 1, pp. 1 - 13
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 01/2009, Volume 23, Issue 1, pp. 65 - 73
Asenapine is a novel psychopharmacologic agent under development for the treatment of schizophrenia and bipolar disorder. We determined and compared the human... 
Schizophrenia | Affinity | Bipolar disorder | Asenapine | Human receptor | NEGATIVE SYMPTOMS | PSYCHIATRY | FOCUS | SEROTONIN RECEPTORS | DISORDERS | RISPERIDONE | schizophrenia | COGNITION | NEUROSCIENCES | CLINICAL NEUROLOGY | bipolar disorder | DOPAMINE D-3 RECEPTOR | PSYCHOSIS | ATYPICAL ANTIPSYCHOTIC-DRUG | PHARMACOLOGY & PHARMACY | asenapine | human receptor | affinity | Humans | Receptors, Serotonin - drug effects | Substrate Specificity | Receptors, Serotonin - genetics | Heterocyclic Compounds, 4 or More Rings - pharmacology | Psychotropic Drugs - therapeutic use | Receptors, Dopamine - drug effects | Clozapine - pharmacology | Histamine Release - genetics | Receptors, Muscarinic - drug effects | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Receptors, Adrenergic - drug effects | Psychotropic Drugs - pharmacology | Cloning, Molecular | Receptors, Adrenergic - genetics | Receptors, Dopamine D2 - drug effects | Inhibitory Concentration 50 | Molecular Structure | Radioligand Assay | Histamine Release - drug effects | Receptors, Muscarinic - genetics | Benzodiazepines - pharmacology | Heterocyclic Compounds, 4 or More Rings - chemistry | Clinical Trials as Topic | Psychotropic Drugs - chemistry | Bipolar Disorder - drug therapy | Receptors, Dopamine D2 - physiology | Schizophrenia - drug therapy | Receptors, Dopamine - genetics | Histamine receptors | Drugs | Neuroleptics | Olanzapine | Acetylcholine receptors (muscarinic) | Mental disorders | Dopamine D4 receptors | Serotonin S1 receptors | Serotonin S7 receptors | Psychotropic drugs | Receptors | Histamine H2 receptors | Risperidone | Dopamine D2 receptors | Dopamine receptors | Binding | Dopamine | Serotonin | Dopamine D3 receptors | Serotonin S6 receptors | Serotonin S2 receptors | Histamine | Dopamine D1 receptors | Serotonin receptors | Receptors (physiology) | Index Medicus
Journal Article
Journal Article
2015, 2015, Neuromethods, ISBN 9781493921959, Volume 96., xiv, 379 pages
Book
Nature Chemical Biology, ISSN 1552-4450, 08/2010, Volume 6, Issue 8, pp. 587 - 594
Journal Article
1980, Receptors and recognition., ISBN 9780412231308, Volume 9-10., 2 v.
Book
1987, Receptor biochemistry and methodology, ISBN 9780845137079, Volume 8, ix, 261
Book
1997, Receptors, ISBN 089603433X, xi, 553
Book
Journal of Neurochemistry, ISSN 0022-3042, 12/2011, Volume 119, Issue 5, pp. 1119 - 1136
Loss of dopaminergic neurons and a-synuclein accumulation are the two major pathological hallmarks of Parkinsons disease. Currently, the mechanisms governing... 
Parkinson's disease | 27-hydroxycholesterol | liver X receptor | estrogen receptors | α-synuclein | tyrosine hydroxylase | CAMP RESPONSE ELEMENT | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | MESSENGER-RNA LEVELS | LXR-ALPHA | NUCLEAR RECEPTOR | BETA-DEFICIENT MICE | GENE-EXPRESSION | INDUCED DOPAMINE DEPLETION | NEURONAL CELLS | RAT-BRAIN | a-synuclein | Humans | Neuroblastoma - enzymology | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | alpha-Synuclein - biosynthesis | Estrogen Receptor beta - biosynthesis | Liver X Receptors | Up-Regulation - physiology | Parkinson Disease - metabolism | alpha-Synuclein - genetics | Estrogen Receptor beta - antagonists & inhibitors | Neuroblastoma - pathology | Orphan Nuclear Receptors - agonists | Tyrosine 3-Monooxygenase - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Signal Transduction - genetics | Down-Regulation - drug effects | Hydroxycholesterols - pharmacology | Orphan Nuclear Receptors - biosynthesis | Disease Progression | Down-Regulation - physiology | Up-Regulation - drug effects | Tyrosine 3-Monooxygenase - biosynthesis | Tyrosine 3-Monooxygenase - genetics | Orphan Nuclear Receptors - antagonists & inhibitors | Parkinson Disease - prevention & control | Parkinson Disease - enzymology | Cell Line, Tumor | Signal Transduction - physiology | Estrogen Receptor alpha - biosynthesis | Neuroblastoma - metabolism
Journal Article
1982, Current reviews in biomedicine, ISBN 0444804285, Volume 2, xii, 179
Book
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 2011, Volume 99, Issue 2, pp. 130 - 145
The investigation of novel drug targets for treating cognitive impairments associated with neurological and psychiatric disorders remains a primary focus of... 
Dopamine | Serotonin | Memory | Attention | Schizophrenia | Glutamate | Glycine | Learning | Histamine | GABA | Acetylcholine | Phosphodiesterase | Alzheimer's | POSITIVE ALLOSTERIC MODULATOR | CONTAINING GABA(A) RECEPTORS | GILL-WITHDRAWAL REFLEX | ALPHA-7 NICOTINIC RECEPTOR | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | LONG-TERM POTENTIATION | METABOTROPIC GLUTAMATE-RECEPTOR | NEUROSCIENCES | MUSCARINIC ACETYLCHOLINE-RECEPTORS | EVENT-RELATED POTENTIALS | HISTAMINE H-3 RECEPTOR | Memory - drug effects | Receptors, Histamine - physiology | Receptors, Serotonin - physiology | Cognition Disorders - physiopathology | Learning - drug effects | Humans | Receptors, Cholinergic - drug effects | Receptors, Serotonin - drug effects | Phosphodiesterase Inhibitors - pharmacology | Receptors, Histamine - drug effects | Cognition Disorders - drug therapy | Receptors, Glutamate - drug effects | Receptors, Cholinergic - physiology | Receptors, Dopamine - drug effects | Learning - physiology | Animals | Glycine Plasma Membrane Transport Proteins - drug effects | Glycine Plasma Membrane Transport Proteins - physiology | Receptors, GABA - physiology | Nootropic Agents - pharmacology | Receptors, Dopamine - physiology | Receptors, Glutamate - physiology | Memory - physiology | Receptors, GABA - drug effects | Nervous system diseases | Attention-deficit hyperactivity disorder | Amyloid beta-protein | Alzheimer's disease
Journal Article