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Science, ISSN 0036-8075, 4/2004, Volume 304, Issue 5667, pp. 108 - 110
In adult mammals, the adipocyte-derived hormone leptin acts on the brain to reduce food intake by regulating the activity of neurons in the arcuate nucleus of... 
Neurites | Neuroscience | Neurons | Food intake | Innervation | Reports | Mice | Adults | Hypothalamus | Hormones | Critical periods | ENERGY-BALANCE | BODY-WEIGHT | NERVOUS-SYSTEM | OBESITY | THYROID-HORMONE | MULTIDISCIPLINARY SCIENCES | BRAIN-DEVELOPMENT | Paraventricular Hypothalamic Nucleus - physiology | Hypothalamus - growth & development | Neurites - physiology | Culture Techniques | Dorsomedial Hypothalamic Nucleus - physiology | Hypothalamic Area, Lateral - cytology | Arcuate Nucleus of Hypothalamus - cytology | Axons - physiology | Proteins - analysis | Arcuate Nucleus of Hypothalamus - growth & development | Carbocyanines | Leptin - physiology | Paraventricular Hypothalamic Nucleus - cytology | Nerve Fibers - physiology | Hypothalamic Area, Lateral - physiology | Neurons - physiology | Leptin - pharmacology | Animals, Newborn | Eating | Signal Transduction | Dorsomedial Hypothalamic Nucleus - cytology | Hypothalamus - physiology | Hypothalamic Area, Lateral - growth & development | Intercellular Signaling Peptides and Proteins | Mice, Inbred C57BL | Feeding Behavior | Leptin - genetics | Recombinant Proteins - pharmacology | Arcuate Nucleus of Hypothalamus - physiology | Animals | Hypothalamus - cytology | Mice, Obese | Dorsomedial Hypothalamic Nucleus - growth & development | Leptin - deficiency | Paraventricular Hypothalamic Nucleus - growth & development | Agouti-Related Protein | alpha-MSH - analysis | Physiological aspects | Chemical properties | Eating (Physiology) | Leptin | Neurology | Nutrition | Rodents
Journal Article
Brain Research, ISSN 0006-8993, 2008, Volume 1227, pp. 128 - 141
Abstract Rats can anticipate a daily mealtime when they are maintained on restricted feeding schedules (RFS). Neural substrates of the food-entrainable... 
Neurology | FEO, food-entrainable oscillator | AHA, anterior hypothalamic area | LEO, light-entrainable oscillator | PVTp, paraventricular thalamic nucleus, posterior part | Restricted feeding schedule | PVHp, paraventricular hypothalamic nucleus, parvocellular part | SuM, supramammillary nucleus | PVH, paraventricular hypothalamic nucleus | HPA, hypothalamic–pituitary adrenal axis | CeA, central nucleus of amygdala | DLG, dorsal lateral geniculate nucleus | PVT, paraventricular thalamic nucleus | Food-entrainable oscillator | AD, anterodorsal thalamic nucleus | SG, suprageniculate thalamic nucleus | BLA, basolateral amygdala | LHA, lateral hypothalamic area | Food anticipation | DMHv, dorsomedial hypothalamic nucleus, ventral part | DTg, dorsal tegmental nucleus | SON, supraoptic nucleus | AH/SHi, anterior hippocampal continuation and septohippocampal nucleus | PVTa, paraventricular thalamic nucleus, anterior part | DMH, dorsomedial hypothalamic nucleus | PVHam, paraventricular hypothalamic nucleus, anterior magnocellular part | c- fos | CRF, corticotropin releasing factor | FAA, food-anticipatory activity | Neuronal activation | ACh, acetylcholine | VMH, ventromedial hypothalamic nucleus | LM, lateral mammillary nucleus | ACTH, adrenocorticotropic hormone | NTS, nucleus of the solitary tract | PB, parabrachial nuclei | CRF | SCN, suprachiasmatic nucleus | RFS, restricted feeding schedules | PVHmm, paraventricular hypothalamic nucleus, medial magnocellular part | SuG, superficial gray layer of the superior colliculus | DMHc, dorsomedial hypothalamic nucleus, compact part | HPA, hypothalamic-pituitary adrenal axis | c-fos | ENHANCED ACETYLCHOLINE-RELEASE | restricted feeding schedule | DORSOMEDIAL HYPOTHALAMIC NUCLEUS | CIRCADIAN-RHYTHMS | food-entrainable oscillator | HORMONE MESSENGER-RNA | NEUROSCIENCES | NEUROSECRETORY NEURONS | PLASMA-CORTICOSTERONE | ZUCKER RATS | PARAVENTRICULAR THALAMIC NUCLEUS | neuronal activation | AGED RATS | food anticipation | C-FOS EXPRESSION | Paraventricular Hypothalamic Nucleus - physiology | Insulin - physiology | Rats, Wistar | Dorsomedial Hypothalamic Nucleus - physiology | Male | Insulin - blood | RNA, Messenger - metabolism | Brain - physiology | Eating - physiology | Brain - metabolism | Paraventricular Hypothalamic Nucleus - cytology | In Situ Hybridization | Neurons - physiology | Corticotropin-Releasing Hormone - genetics | Neurons - metabolism | Corticosterone - blood | Gene Expression | Enzyme-Linked Immunosorbent Assay | Dorsomedial Hypothalamic Nucleus - cytology | RNA, Messenger - genetics | Amygdala - metabolism | Proto-Oncogene Proteins c-fos - metabolism | Rats | Amygdala - cytology | Dorsomedial Hypothalamic Nucleus - metabolism | Hippocampus - cytology | Corticotropin-Releasing Hormone - metabolism | Feeding Behavior - physiology | Food Deprivation - physiology | Hippocampus - metabolism | Animals | Glucose - physiology | Paraventricular Hypothalamic Nucleus - metabolism | Proto-Oncogene Proteins c-fos - genetics | Corticosterone - metabolism | Body Weight - physiology | Glucose - analysis | Hippocampus - physiology | Amygdala - physiology
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2003, Volume 23, Issue 33, pp. 10691 - 10702
The suprachiasmatic nucleus (SCN) contains the brain's circadian pacemaker, but mechanisms by which it controls circadian rhythms of sleep and related... 
Suprachiasmatic nucleus | Corticosteroid | Melatonin | Sleep | Locomotor activity | Feeding | EFFERENT PROJECTIONS | PHASEOLUS-VULGARIS-LEUKOAGGLUTININ | GOLDEN-HAMSTER | SUBPARAVENTRICULAR ZONE | NEUROSCIENCES | sleep | PARAVENTRICULAR NUCLEUS | VENTROLATERAL PREOPTIC NUCLEUS | feeding | corticosteroid | locomotor activity | GALANINERGIC NEURONS | RAT-BRAIN | suprachiasmatic nucleus | melatonin | Darkness | Fluorescent Dyes - pharmacokinetics | Ibotenic Acid - administration & dosage | Wakefulness - drug effects | Dorsomedial Hypothalamic Nucleus - physiology | Motor Activity - drug effects | Male | Neural Pathways - physiology | Suprachiasmatic Nucleus - physiology | Melatonin - blood | Behavior, Animal - drug effects | Stilbamidines - administration & dosage | Sleep - physiology | Fluorescent Dyes - administration & dosage | Neurotoxins - administration & dosage | Preoptic Area - physiology | Dorsomedial Hypothalamic Nucleus - drug effects | Cholera Toxin - administration & dosage | Microinjections | Stilbamidines - pharmacokinetics | Rats | Behavior, Animal - physiology | Circadian Rhythm - physiology | Rats, Sprague-Dawley | Sleep - drug effects | Feeding Behavior - drug effects | Animals | Cholera Toxin - pharmacokinetics | Wakefulness - physiology | Adrenal Cortex Hormones - blood | Circadian Rhythm - drug effects | Behavioral | Cognitive | Systems
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2010, Volume 30, Issue 30, pp. 10220 - 10232
Diet restriction retards aging and extends lifespan by triggering adaptive mechanisms that alter behavioral, physiological, and biochemical responses in... 
LIFE-SPAN EXTENSION | ENERGY-BALANCE | STIMULATED INSULIN-SECRETION | CAENORHABDITIS-ELEGANS | C-FOS | FOOD-ANTICIPATORY ACTIVITY | MICE | SACCHAROMYCES-CEREVISIAE | NEUROSCIENCES | INCREASED DOSAGE | CALORIE RESTRICTION | Enzyme-Linked Immunosorbent Assay - methods | Sirtuin 1 - metabolism | Receptors, G-Protein-Coupled - metabolism | Body Temperature - drug effects | Adaptation, Physiological - drug effects | Dorsomedial Hypothalamic Nucleus - physiology | Hypothalamic Area, Lateral - cytology | Motor Activity - drug effects | Male | Receptors, Neuropeptide - metabolism | RNA, Messenger - metabolism | Sirtuin 1 - genetics | Brain - metabolism | Hypothalamic Area, Lateral - physiology | Statistics, Nonparametric | Chromatin Immunoprecipitation - methods | Female | Neurons - metabolism | Sirtuin 1 - deficiency | Neurons - drug effects | Dorsomedial Hypothalamic Nucleus - drug effects | Dorsomedial Hypothalamic Nucleus - cytology | Mice, Inbred C57BL | Adaptation, Physiological - physiology | Receptors, Neuropeptide - genetics | Ghrelin - pharmacology | Up-Regulation - genetics | Orexin Receptors | Food Deprivation - physiology | Motor Activity - genetics | Ghrelin - blood | Microdissection - methods | Animals | Body Temperature - genetics | Hypothalamic Area, Lateral - drug effects | Mice | Receptors, G-Protein-Coupled - genetics
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 05/2005, Volume 32, Issue 5, pp. 419 - 425
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 08/2016, Volume 311, Issue 2, pp. H433 - H444
Hypothalamic arcuate nucleus (ARCN) stimulation elicited increases in sympathetic nerve activity (IBATSNA) and temperature (T-BAT) of interscapular brown... 
Glutamate receptors | Bat nerve activity | Melanocortin receptors | Dorsomedial nucleus | Interscapular brown adipose tissue | Proopiomelanocortin | Paraventricular nucleus | Brown adipose tissue temperature | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | bat nerve activity | interscapular brown adipose tissue | RAT | brown adipose tissue temperature | RECEPTOR MESSENGER-RNA | BRAIN-STEM | SYSTEM REGULATION | PREOPTIC AREA | SYMPATHETIC OUTFLOW | NEUROPEPTIDE-Y | ARTERIAL-PRESSURE | FEEDING-BEHAVIOR | NEURONS | proopiomelanocortin | PERIPHERAL VASCULAR DISEASE | dorsomedial nucleus | melanocortin receptors | glutamate receptors | paraventricular nucleus | Immunohistochemistry | Muscimol - pharmacology | Paraventricular Hypothalamic Nucleus - physiology | Temperature | Neural Inhibition | Rats, Wistar | Sympathetic Nervous System - drug effects | 2-Amino-5-phosphonovalerate - pharmacology | Dorsomedial Hypothalamic Nucleus - physiology | Male | alpha-MSH - metabolism | N-Methylaspartate - pharmacology | Quinoxalines - pharmacology | Thermogenesis - physiology | Adipose Tissue, Brown - innervation | Sympathetic Nervous System - physiology | GABA-A Receptor Agonists - pharmacology | Arcuate Nucleus of Hypothalamus - drug effects | Dorsomedial Hypothalamic Nucleus - drug effects | Receptor, Melanocortin, Type 4 - antagonists & inhibitors | Microinjections | Rats | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Arcuate Nucleus of Hypothalamus - physiology | Vesicular Glutamate Transport Proteins - metabolism | Pro-Opiomelanocortin - metabolism | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Receptor, Melanocortin, Type 3 - antagonists & inhibitors | Stilbamidines | 2-Amino-5-phosphonovalerate - analogs & derivatives | Adipose Tissue, Brown - drug effects | Glutamic Acid - metabolism | Thermogenesis - drug effects | Fluorescent Dyes | Physiological aspects | Nervous system, Sympathetic | Metabotropic glutamate receptors | Brown adipose tissue | Cardiovascular Neurohormonal Regulation
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 04/2009, Volume 29, Issue 7, pp. 1447 - 1460
Circadian rhythms in mammals are regulated by a light-entrainable circadian pacemaker in the hypothalamic suprachiasmatic nucleus and food-entrainable... 
Suprachiasmatic nucleus | Food entrainment | Period genes | MBMAL1 | Arcuate nucleus | mBMAL1 | RATS | FEEDING SCHEDULES | NEUROSCIENCES | food entrainment | ORGANIZATION | ENTRAINMENT | arcuate nucleus | METABOLISM | OSCILLATORS | LIVER | LAMINA TERMINALIS | suprachiasmatic nucleus | PHASE-SHIFT | Motor Activity - physiology | Dorsomedial Hypothalamic Nucleus - physiology | Receptors, N-Methyl-D-Aspartate - metabolism | Male | Intracellular Signaling Peptides and Proteins - metabolism | Body Temperature - physiology | RNA, Messenger - metabolism | Neocortex - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Cycle Proteins - genetics | Nuclear Proteins - genetics | Solitary Nucleus - metabolism | Intracellular Signaling Peptides and Proteins - genetics | ARNTL Transcription Factors | Basic Helix-Loop-Helix Transcription Factors - genetics | Arcuate Nucleus of Hypothalamus - metabolism | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Gene Expression Regulation | Nuclear Proteins - metabolism | Circadian Rhythm - physiology | Photoperiod | Transcription Factors - genetics | Period Circadian Proteins | Feeding Behavior - physiology | Transcription Factors - metabolism | Food Deprivation - physiology | Animals | Mice | Body Weight - physiology | Circadian rhythms | Methyl aspartate | Brain | Messenger RNA | Universities and colleges | Gene expression
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 2008, Volume 192, Issue 2, pp. 185 - 190
The hypothalamus plays especially important roles in various endocrine, autonomic, and behavioral responses that guarantee the survival of both the individual... 
Defensive behaviors | RET | Anterior hypothalamic nucleus | Ventromedial hypothalamic nucleus | Mouse | Dorsal premammillary nucleus | CAT ODOR | BRAIN-REGIONS | PHASEOLUS-VULGARIS-LEUKOAGGLUTININ | defensive behaviors | RAT | anterior hypothalamic nucleus | FOS IMMUNOREACTIVITY | NEUROSCIENCES | ventromedial hypothalamic nucleus | mouse | PREDATORY ODOR | MESSENGER-RNA | BEHAVIORAL SCIENCES | STRESS | dorsal premammillary nucleus | BEHAVIORS | Immunohistochemistry | Predatory Behavior - physiology | Hypothalamic Area, Lateral - metabolism | Paraventricular Hypothalamic Nucleus - physiology | Species Specificity | Rats, Long-Evans | Dorsomedial Hypothalamic Nucleus - physiology | Male | Ventromedial Hypothalamic Nucleus - physiology | Preoptic Area - metabolism | Fear - physiology | Neural Pathways - physiology | Hypothalamic Area, Lateral - physiology | Preoptic Area - physiology | Hypothalamus - physiology | Proto-Oncogene Proteins c-fos - analysis | Proto-Oncogene Proteins c-fos - metabolism | Rats | Behavior, Animal - physiology | Ventromedial Hypothalamic Nucleus - metabolism | Dorsomedial Hypothalamic Nucleus - metabolism | Escape Reaction - physiology | Animals | Hypothalamus - metabolism | Anterior Hypothalamic Nucleus - physiology | Paraventricular Hypothalamic Nucleus - metabolism | Freezing Reaction, Cataleptic - physiology | Neural Pathways - metabolism | Anterior Hypothalamic Nucleus - metabolism | Mice | Animal behavior | Investigations
Journal Article