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Cell Calcium, ISSN 0143-4160, 01/2019, Volume 77, pp. 68 - 76
The 5' AMP-activated protein kinase (AMPK) is a nutrient-sensitive kinase that plays a key role in the control of cellular energy metabolism. We have explored... 
Dorsomorphin | Inositol-1,4,5-trisphosphate receptor | signaling | AMPK | A769662 | Endoplasmic reticulum
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 08/2019, Volume 671, pp. 1 - 7
Maternal Embryonic Leucine Zipper Kinase (MELK) is overexpressed in various tumors which has been convincingly linked to tumor cell survival. As such, MELK... 
Dorsomorphin | MELK | Structure | Kinase | Cancer | DNA binding proteins | Vascular endothelial growth factor | Crystals
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1891, pp. 91 - 114
The BMP signaling pathway has been shown to be involved in different aspects of embryonic development across diverse metazoan phyla. Comparative studies on the... 
Dorsomorphin | Amphioxus | Embryo | BMP | In situ hybridization | Immunostaining
Journal Article
Cell Calcium, ISSN 0143-4160, 01/2019, Volume 77, pp. 68 - 76
The 5' AMP-activated protein kinase (AMPK) is a nutrient-sensitive kinase that plays a key role in the control of cellular energy metabolism. We have explored... 
Dorsomorphin | AMPK | Inositol-1,4,5-trisphosphate receptor | A769662 | Ca2+ signaling | Endoplasmic reticulum | CANCER-CELLS | APOPTOSIS | Inositol-14 5-trisphosphate receptor | MECHANISM | UPSTREAM | PROTEIN-KINASE | SIGNALS | MTOR | CELL BIOLOGY | SMOOTH-MUSCLE | CALCIUM
Journal Article
Gene, ISSN 0378-1119, 07/2018, Volume 663, pp. 65 - 71
Though the roles of BMP signaling in development is studied extensively in insects and vertebrates, our knowledge of BMP signaling in molluscan development is... 
Dorsomorphin | BMP signaling | Dorsal-ventral patterning | Mollusc | Shell field | BILATERIA | CRASSOSTREA-GIGAS | SUGGESTS | DROSOPHILA | EXPRESSION PATTERNS | SIGNALING PATHWAY | SHELL DEVELOPMENT | GENETICS & HEREDITY | EVO-DEVO | SUPERFAMILY | DIFFERENTIATION
Journal Article
Andrologia, ISSN 0303-4569, 04/2019, Volume 51, Issue 3, pp. e13196 - n/a
This study examined the effects of PI3K and AMPK signalling pathway inhibitors on leptin‐induced adverse effects on rat spermatozoa. Sprague‐Dawley rats, aged... 
LY294002 | dorsomorphin | PI3K | leptin | sperm parameters | SIGNALING PATHWAYS | ANDROLOGY | Spermatozoa | Leptin | Signal transduction | Side effects | Deoxyguanosine | Sperm | Morphology | Body weight | Data processing | AKT protein | 1-Phosphatidylinositol 3-kinase
Journal Article
Cancer Biology and Medicine, ISSN 2095-3941, 04/2019, Volume 16, Issue 2, pp. 220 - 233
Heat shock factor 1 (HSF1), a transcriptional regulator of heat shock proteins (HSPs), is an attractive therapeutic target for cancer. However, only a few HSF1... 
Dorsomorphin | Heat shock factor 1 | Heat shock protein | Apoptosis | Cancer | heat shock factor 1 | apoptosis | heat shock protein | cancer | Original
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1891, pp. 221 - 233
The bone morphogenetic protein (BMP) signaling pathway, a subset of the transforming growth factor β (TGF-β) signaling family, consists of structurally diverse... 
Dorsomorphin | LDN-212854 | DMH1 | LDN-214117 | K02288a | LDN-193189 | SB-431452 | Bone morphogenetic protein (BMP) signaling | Kinase inhibitor | kinase inhibitor | bone morphogenetic protein (BMP) signaling
Journal Article
FASEB Journal, ISSN 0892-6638, 10/2015, Volume 29, Issue 10, pp. 4299 - 4312
Zebrafish fin regeneration involves initial formation of the wound epidermis and the blastema, followed by tissue morphogenesis. The mechanisms coordinating... 
Blastemal | Regenerative angiogenesis | Wound epithelium | regenerative angiogenesis | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE | DORSOMORPHIN | DEDIFFERENTIATION | BLASTEMA | INDUCTION | CELL BIOLOGY | blastemal | GROWTH | BIOLOGY | DIFFERENTIATION | RECEPTORS | wound epithelium | SONIC-HEDGEHOG | Bone Morphogenetic Proteins - antagonists & inhibitors | Blood Vessels - growth & development | Animal Fins - surgery | Blood Vessels - metabolism | Green Fluorescent Proteins - genetics | Quinolines - pharmacology | Bone Morphogenetic Proteins - metabolism | In Situ Hybridization | Epidermis - physiopathology | Regeneration - genetics | Animal Fins - physiopathology | Epidermis - injuries | Collagen - genetics | Bone Morphogenetic Proteins - genetics | Pyrazoles - pharmacology | Epidermis - metabolism | Green Fluorescent Proteins - metabolism | Animal Fins - metabolism | Morphogenesis - genetics | Animals, Genetically Modified | Zebrafish Proteins - metabolism | Gene Expression Regulation, Developmental - drug effects | Signal Transduction - genetics | Inhibitor of Differentiation Protein 1 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Zebrafish - genetics | Collagen - metabolism | Microscopy, Confocal | Animals | Zebrafish - metabolism | Inhibitor of Differentiation Protein 1 - genetics | Zebrafish - physiology | Zebrafish Proteins - genetics | Microscopy, Fluorescence
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 11/2018, Volume 28, Issue 20, pp. 3356 - 3362
Journal Article
AUTOPHAGY, ISSN 1554-8627, 07/2015, Volume 11, Issue 7, pp. 1114 - 1129
Autophagy is induced during differentiation of human monocytes into macrophages that is mediated by CSF1/CSF-1/M-CSF (colony stimulating factor 1... 
apoptosis-related cysteine peptidase | ACTIVATION | CSF1 | DRS | EMR1 EGF-like module-containing mucin-like hormone receptor-like 1 | CSF1 colony stimulating factor 1 (macrophage) | UPSTREAM KINASE | PRKAA protein kinase AMP-activated | TFRC transferrin receptor | CELL BIOLOGY | caspase 8 | MAP1LC3B | CASP8 | STK11 serine | CMML | CALMODULIN | ULK1 unc-51 like autophagy activating kinase 1 | calmodulin-dependent protein kinase kinase 2 | UDP | autophagy | CMML chronic myelomonocytic leukemia | PLCB3 phospholipase C | CFLAR CASP8 and FADD-like apoptosis regulator | PLCG2 phospholipase C gamma 2 (phosphatidylinositol-specific) | G-protein coupled 6 | DEGRADATION | PRKAA1 protein kinase AMP-activated 1 catalytic subunit | PRKAA1 | differentiation | PHOSPHORYLATION | ITGAM integrin M | DEFA3 defensin 3 neutrophil-specific | ACTB actin | LC3B microtubule-associated protein 1 light chain 3 | primary monocyte | CAMKK2 | RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 | P2RY6 pyrimidinergic receptor P2Y | AMPK1 | P2RY6 | UDP uridine diphosphate | DEFA1 defensin 1 | CELLS | calcium | WT wild-type | dorsomorphin | FADD Fas (TNFRSF6)-associated via death domain | 3 (phosphatidylinositol-specific) | PROTEIN-KINASE | MACROPHAGES | CSF1R colony stimulating factor 1 receptor | PRKAA2 protein kinase AMP-activated 2 catalytic subunit | PRKAG1 protein kinase AMP-activated gamma 1 noncatalytic subunit | PLC phospholipase | threonine kinase 11 | CHRONIC MYELOMONOCYTIC LEUKEMIA
Journal Article
Expert Opinion on Therapeutic Patents, ISSN 1354-3776, 10/2016, Volume 26, Issue 10, pp. 1115 - 1128
Introduction: The bone morphogenetic protein (BMP) is a critical signaling pathway and plays a diverse role in embryonic pattern formation and is implicated in... 
ALK | inhibitors | small molecule | Bone morphogenetic protein | BMP | activin receptor-like kinase | OSTEOBLAST | CHEMISTRY, MEDICINAL | INTRINSIC PONTINE GLIOMA | DORSOMORPHIN | RECEPTOR | CANCER | ROLES | GROWTH | PHARMACOLOGY & PHARMACY | DIFFERENTIATION | HIGH-GRADE GLIOMA | FIBRODYSPLASIA OSSIFICANS PROGRESSIVA
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1732, pp. 195 - 202
Journal Article