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PLoS Biology, ISSN 1544-9173, 12/2015, Volume 13, Issue 12, p. e1002318
Detecting danger is one of the foremost tasks for a neural system. Larval parasitoids constitute clear danger to Drosophila, as up to 80% of fly larvae become... 
ODORS | PHEROMONE | EVOLUTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | RECEPTOR | SPATIAL REPRESENTATION | SELECTION | MAP | AGGRESSION | PREFERENCE | FLIES | Receptors, Odorant - metabolism | Drosophila melanogaster - physiology | Olfactory Bulb - metabolism | Drosophila Proteins - agonists | Drosophila Proteins - metabolism | Wasps - metabolism | Drosophila melanogaster - genetics | Odorants | Receptors, Odorant - agonists | Terpenes - pharmacology | Protein Isoforms - metabolism | Protein Isoforms - agonists | Larva - drug effects | Behavior, Animal - drug effects | Female | Larva - genetics | Sensory Receptor Cells - metabolism | Alkaloids - pharmacology | Signal Transduction | Animals, Genetically Modified | Nerve Tissue Proteins - agonists | Mutant Proteins - metabolism | Nerve Tissue Proteins - genetics | Drosophila melanogaster - drug effects | Nerve Tissue Proteins - metabolism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Sensory Receptor Cells - drug effects | Iridoids - pharmacology | Larva - parasitology | Receptors, Odorant - genetics | Drosophila melanogaster - parasitology | Oviposition | Pyridines - pharmacology | Drosophila Proteins - genetics | Larva - physiology | Olfactory Bulb - drug effects | Mutant Proteins - agonists | Biological Sciences | Biologi | Naturvetenskap | Natural Sciences | Zoologi | Zoology | Ligands | Behavior | Insects | Females | Neurons
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2015, Volume 11, Issue 4, p. e1004794
Monoamines, such as 5-HT and tyramine (TA), paralyze both free-living and parasitic nematodes when applied exogenously and serotonergic agonists have been used... 
BIOACTIVITY | INFECTIONS | INDUCED PARALYSIS | FUNCTIONAL RECONSTITUTION | MICROBIOLOGY | GATED CHLORIDE CHANNEL | HAEMONCHUS-CONTORTUS | VIROLOGY | PROTEIN-COUPLED RECEPTOR | IN-VIVO | RESISTANCE | SEROTONIN | PARASITOLOGY | GTP-Binding Protein alpha Subunits - chemistry | Humans | Receptors, Biogenic Amine - genetics | Caenorhabditis elegans Proteins - metabolism | Motor Activity - drug effects | Serotonin 5-HT1 Receptor Agonists - pharmacology | Drug Discovery - methods | Drosophila Proteins - agonists | Drosophila Proteins - metabolism | Caenorhabditis elegans Proteins - agonists | Behavior, Animal - drug effects | Helminth Proteins - metabolism | Recombinant Proteins - metabolism | Caenorhabditis elegans - metabolism | GTP-Binding Protein alpha Subunits - metabolism | Caenorhabditis elegans - genetics | Chloride Channel Agonists - pharmacology | Nerve Tissue Proteins - agonists | Interneurons - drug effects | Recombinant Proteins - chemistry | GTP-Binding Protein alpha Subunits - genetics | Helminth Proteins - genetics | Recombinant Proteins - genetics | Hypotonic Solutions - toxicity | Animals, Genetically Modified - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Caenorhabditis elegans - drug effects | Interneurons - metabolism | Animals, Genetically Modified - genetics | Anthelmintics - pharmacology | Receptors, Biogenic Amine - metabolism | Haemonchus | Helminth Proteins - agonists | Drosophila Proteins - genetics | Caenorhabditis elegans Proteins - genetics | Drosophila melanogaster | Receptors, Biogenic Amine - agonists | Proteins | Nematodes | Parasites | Mutation | Permeability | Worms
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2011, Volume 31, Issue 38, pp. 13357 - 13375
Journal Article
Immunity, ISSN 1074-7613, 06/2009, Volume 30, Issue 6, pp. 789 - 801
Cellular inhibitor of apoptosis proteins (cIAPs) block apoptosis, but their physiological functions are still under investigation. Here, we report that cIAP1... 
MOLIMMUNO | CELLS | ACTIVATION | C-IAP1 | PROTEIN | DROSOPHILA IMD PATHWAY | IN-VIVO | KINASE | IMMUNOLOGY | POLYUBIQUITINATION | NF-KAPPA-B | RIP2 | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Receptors, Pattern Recognition - immunology | Inhibitor of Apoptosis Proteins - genetics | Nod1 Signaling Adaptor Protein - agonists | Colitis - pathology | Baculoviral IAP Repeat-Containing 3 Protein | Nod1 Signaling Adaptor Protein - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Receptors, Pattern Recognition - agonists | Nod2 Signaling Adaptor Protein - agonists | Inhibitor of Apoptosis Proteins - metabolism | Colitis - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Cytokines - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Nod2 Signaling Adaptor Protein - immunology | Ubiquitination - immunology | Nod1 Signaling Adaptor Protein - immunology | Immunity, Innate | Mice, Knockout | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Ubiquitin-Protein Ligases | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Apoptosis - immunology | Colitis - enzymology | Nod2 Signaling Adaptor Protein - metabolism | Signal Transduction - drug effects | Inhibitor of Apoptosis Proteins - immunology | Mice | Ubiquitin | Oligomers | Ligases | Physiological aspects | Crohn's disease | Colitis | Apoptosis | Medical research | Enzymes | Statistical analysis | Cytokines | Kinases | Proteins | Inflammatory bowel disease | Genotype & phenotype | Insects | Bacteria | Gram-negative bacteria | Chemokines | Immune system
Journal Article
Nature Communications, ISSN 2041-1723, 10/2016, Volume 7, Issue 1, p. 13135
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 50, pp. 20599 - 20612
The short neuropeptide F (sNPF) neuropeptides, closely related to vertebrate neuropeptide Y (NPY), have been suggested to exert pleiotropic effects on many... 
signaling | DROSOPHILA-MELANOGASTER | neuropeptide | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSECT CELLS | Bombyx mori | ANOPHELES-GAMBIAE | FUNCTIONAL-CHARACTERIZATION | TSETSE-FLY | silkworm | N-LINKED GLYCOSYLATION | FEEDING-BEHAVIOR | G protein-coupled receptor (GPCR) | GENE-EXPRESSION | GLOSSINA-MORSITANS-MORSITANS | NEUROHORMONE GPCRS | short neuropeptide F | GTP-Binding Protein alpha Subunits, Gi-Go - agonists | Phosphorylation | Receptors, G-Protein-Coupled - metabolism | Humans | Receptors, Neuropeptide - metabolism | Receptors, G-Protein-Coupled - agonists | Recombinant Fusion Proteins - metabolism | MAP Kinase Signaling System | Spodoptera | Bombyx - metabolism | Sf9 Cells | Protein Isoforms - metabolism | Protein Isoforms - agonists | HEK293 Cells | Insect Proteins - agonists | Receptors, Neuropeptide - agonists | Neuropeptides - genetics | Insect Proteins - metabolism | Peptide Fragments - genetics | Calcium Signaling | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Down-Regulation | Gene Expression Regulation | Insect Proteins - genetics | Receptors, Neuropeptide - genetics | Recombinant Proteins - chemistry | Neuropeptides - metabolism | Recombinant Fusion Proteins - chemistry | Protein Transport | Peptide Fragments - chemistry | Animals | GTP-Binding Protein alpha Subunits, Gi-Go - antagonists & inhibitors | Insect Proteins - chemistry | Protein Processing, Post-Translational | Receptors, G-Protein-Coupled - genetics | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism | Neuropeptides - chemistry | Protein Isoforms - genetics | Signal Transduction
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 35, pp. 14334 - 14348
Synaptic vesicles (SVs) form distinct pools at synaptic terminals, and this well-regulated separation is necessary for normal neurotransmission. However, how... 
LOCALIZATION | RECRUITMENT | EXCHANGE FACTOR | EXOCYTOSIS | SYNAPSES | BIOCHEMISTRY & MOLECULAR BIOLOGY | AUTISM SPECTRUM DISORDER | DYNAMICS | CELL-ADHESION | POLYMERIZATION | DROSOPHILA NEUREXIN | Neuromuscular Junction - cytology | Synaptic Vesicles - metabolism | Neuromuscular Junction - metabolism | Humans | Protein Multimerization | rac GTP-Binding Proteins - metabolism | Green Fluorescent Proteins - genetics | Drosophila Proteins - agonists | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Recombinant Fusion Proteins - metabolism | rac GTP-Binding Proteins - agonists | Drosophila melanogaster - metabolism | ATP-Binding Cassette Transporters - chemistry | Nerve Tissue Proteins - chemistry | ATP-Binding Cassette Transporters - genetics | Gene Deletion | Larva - growth & development | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Cell Adhesion Molecules, Neuronal - metabolism | Larva - genetics | Membrane Proteins - metabolism | Protein Interaction Domains and Motifs | Peptide Fragments - genetics | Green Fluorescent Proteins - metabolism | Peptide Fragments - metabolism | Actin Cytoskeleton - metabolism | Cell Adhesion Molecules, Neuronal - chemistry | Animals, Genetically Modified | Membrane Proteins - genetics | Larva - metabolism | Drosophila melanogaster - cytology | Drosophila Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Nerve Tissue Proteins - genetics | Cell Adhesion Molecules, Neuronal - genetics | Larva - cytology | Nerve Tissue Proteins - metabolism | Neuromuscular Junction - growth & development | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | rac GTP-Binding Proteins - chemistry | Drosophila melanogaster - growth & development | Drosophila Proteins - genetics | Electrophysiological Phenomena | Mutation | actin | synapse | cell adhesion | Drosophila | Neurobiology | vesicles
Journal Article