X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (7740) 7740
Book Review (1282) 1282
Publication (658) 658
Book / eBook (248) 248
Newsletter (165) 165
Newspaper Article (140) 140
Conference Proceeding (89) 89
Book Chapter (80) 80
Magazine Article (25) 25
Report (13) 13
Government Document (12) 12
Dissertation (9) 9
Trade Publication Article (6) 6
Web Resource (4) 4
Reference (3) 3
Data Set (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (6354) 6354
humans (4754) 4754
animals (2131) 2131
female (1945) 1945
male (1911) 1911
drugs (1376) 1376
cancer (1067) 1067
analysis (1047) 1047
middle aged (1001) 1001
drug discovery (995) 995
research (981) 981
adult (976) 976
drug repositioning (926) 926
pharmacology & pharmacy (922) 922
drug therapy (857) 857
proteins (834) 834
aged (750) 750
biochemistry & molecular biology (737) 737
mice (735) 735
medicine (657) 657
multidisciplinary sciences (632) 632
care and treatment (626) 626
oncology (623) 623
article (622) 622
pharmacology (622) 622
treatment outcome (616) 616
health aspects (613) 613
research article (598) 598
gene expression (542) 542
surgery (524) 524
cell biology (515) 515
rats (492) 492
chemotherapy (451) 451
biology (448) 448
studies (427) 427
cell line, tumor (424) 424
neurosciences (424) 424
in-vitro (417) 417
therapy (410) 410
disease (404) 404
methods (402) 402
abridged index medicus (397) 397
apoptosis (396) 396
medical research (395) 395
science (390) 390
dose-response relationship, drug (379) 379
expression (378) 378
drug development (362) 362
usage (361) 361
drug design (358) 358
discovery (350) 350
models, molecular (347) 347
genes (346) 346
algorithms (341) 341
physiological aspects (338) 338
clinical trials (335) 335
medicine & public health (335) 335
time factors (325) 325
biochemistry (320) 320
patients (320) 320
tumors (318) 318
antineoplastic agents - pharmacology (313) 313
inhibition (310) 310
inhibitors (310) 310
binding sites (308) 308
drug resistance (303) 303
chemistry, medicinal (302) 302
identification (302) 302
ligands (302) 302
protein binding (301) 301
adolescent (299) 299
genetic aspects (299) 299
kinases (299) 299
mutation (296) 296
drug discovery - methods (294) 294
drug repositioning - methods (291) 291
biochemical research methods (287) 287
cancer therapies (286) 286
cells (284) 284
prospective studies (283) 283
bioinformatics (280) 280
endocrinology & metabolism (276) 276
mathematical & computational biology (272) 272
disease models, animal (271) 271
aged, 80 and over (269) 269
biotechnology & applied microbiology (268) 268
clinical neurology (268) 268
drug approval (268) 268
genomics (266) 266
pharmaceutical industry (264) 264
computational biology - methods (261) 261
child (259) 259
drug repurposing (259) 259
cell proliferation - drug effects (254) 254
medicine, research & experimental (254) 254
structure-activity relationship (254) 254
enzymes (252) 252
molecular biology (252) 252
metabolism (247) 247
risk factors (245) 245
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (157) 157
Robarts - Stacks (15) 15
Collection Dvlpm't (Acquisitions) - Closed Orders (12) 12
Collection Dvlpm't (Acquisitions) - Vendor file (11) 11
UTL at Downsview - May be requested (9) 9
Online Resources - Online (7) 7
UofT at Mississauga - Stacks (7) 7
Gerstein Science - Missing (4) 4
Humber River Regional Hospital - Church Stacks (4) 4
Dentistry (Harry R Abbott) - Stacks (3) 3
Providence Healthcare - Stacks (3) 3
St. Michael's Hospital - Stacks (3) 3
UofT at Scarborough - Stacks (3) 3
Credit Valley Hospital - Stacks (2) 2
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (2) 2
Lakeridge Health Sciences - Oshawa (2) 2
Markham Stouffville Hospital - Stacks (2) 2
Scarborough Hospital - Birchmount (2) 2
Scarborough Hospital - General (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (2) 2
Toronto East General Hospital - Stacks (2) 2
Trillium Health Centre - Stacks (2) 2
West Park Healthcare Centre - Stacks (2) 2
Women's College Hospital - Stacks (2) 2
Baycrest Hospital - Stacks (1) 1
Chemistry (A D Allen) - Stacks (1) 1
Credit Valley Hospital - Missing (1) 1
Dentistry (Harry R Abbott) - May be requested (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reference (1) 1
Humber River Regional Hospital - Finch Stacks (1) 1
Innis College - Stacks (1) 1
Providence Healthcare - Lost (1) 1
Providence Healthcare - Reference (1) 1
Scarborough Hospital - Hospital Department (1) 1
St. Michael's College (John M. Kelly) - 1st Floor (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
Sunnybrook Health Sciences Centre - Holland Stacks (1) 1
Toronto East General Hospital - Online (1) 1
University College (Laidlaw) - Stacks (1) 1
UofT at Scarborough - Bindery (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8430) 8430
French (10) 10
Spanish (9) 9
German (8) 8
Chinese (3) 3
Japanese (2) 2
Russian (2) 2
Arabic (1) 1
Czech (1) 1
Dutch (1) 1
Hebrew (1) 1
Korean (1) 1
Polish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Bioinformatics (Oxford, England), ISSN 1367-4803, 10/2014, Volume 30, Issue 20, pp. 2923 - 2930
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1903, pp. 291 - 316
Using existing drugs for diseases which are not developed for their treating (drug repositioning) provides a new approach to developing drugs at a lower cost,... 
Drug repositioning | Disease-target relations | Drug-target relations | Heterogeneous label propagation | Drug-disease relations | Semi-supervised learning | Computational Biology - methods | Algorithms | Supervised Machine Learning | Humans | Drug Repositioning - methods
Journal Article
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 10/2013, Volume 14, Issue 16, pp. S3 - S3
Journal Article
Oncogene, ISSN 0950-9232, 01/2018, Volume 37, Issue 3, pp. 403 - 414
Computation-based drug-repurposing/repositioning approaches can greatly speed up the traditional drug discovery process. To date, systematic and comprehensive... 
STEM-CELLS | ONCOLOGY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | PREVENTION | RISK | DISEASE GENETICS PREDICTION | HEALTH | CELL BIOLOGY | Humans | Neoplasms, Glandular and Epithelial - epidemiology | Drug Discovery - methods | Gene Expression Profiling | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Incidence | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Indomethacin - therapeutic use | Female | Genomics - methods | Ovarian Neoplasms - drug therapy | Computational Biology - methods | Sequence Homology, Nucleic Acid | beta Catenin - metabolism | Indomethacin - pharmacology | Ovarian Neoplasms - epidemiology | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Chemotherapy, Adjuvant - methods | Drug Repositioning - methods | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Cell Line, Tumor | Mice | Drugs | Cell death | Oncology, Experimental | Genomics | Stem cells | Research | Drug discovery | Indomethacin | Drug therapy | Epidemiology | Ovarian cancer | Cancer | Clinical trials | Drug development | Cancer therapies | Cisplatin | Nonsteroidal antiinflammatory drugs | β-catenin | Platinum | Cell lines | Computer applications | Index Medicus | Oncogenomics
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1903, pp. 61 - 72
The protocol below describes an in silico method for drug repositioning (drug repurposing). The data source is ClinicalTrials.gov , which contains about a... 
Text mining | Indication discovery | ClinicalTrials.gov | PolyAnalyst | Adverse event | Drug repositioning | Drug repurposing | I2E | User-Computer Interface | Computational Biology - methods | Algorithms | Drug-Related Side Effects and Adverse Reactions | Humans | Drug Repositioning - methods | Software | Data Mining - methods | Databases, Factual
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1903, pp. 97 - 113
The wealth of knowledge and omic data available in drug research allowed the rising of several computational methods in drug discovery field yielding a novel... 
Interaction networks | Drug repositioning | Drug-target interaction prediction | Precision medicine | Network-based drug repurposing | Gene Expression Regulation - drug effects | Computational Biology - methods | Algorithms | Humans | Drug Repositioning - methods | Ligands | Research | Gene Regulatory Networks | Drug Discovery | Precision Medicine
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 11/2013, Volume 9, Issue 11, pp. e1003315 - e1003315
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 08/2016, Volume 1415, pp. 441 - 462
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 09/2015, Volume 16, Issue 13, pp. S4 - S4
Background: Drug repositioning is a cost-efficient and time-saving process to drug development compared to traditional techniques. A systematic method to drug... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | THERAPEUTIC TARGET DATABASE | DISEASE | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | ASTHMA | UPDATE | INNOVATION | CANCER | DISCOVERY | Databases, Factual - utilization | Drug Repositioning - methods | Proteins - chemistry | Databases | Authorship | Health aspects | Drug interactions | Interactomes | Index Medicus
Journal Article
16.