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1. Full Text Azole fungicides – understanding resistance mechanisms in agricultural fungal pathogens
by Price, Claire L and Parker, Josie E and Warrilow, Andrew GS and Kelly, Diane E and Kelly, Steven L
Pest management science, ISSN 1526-498X, 08/2015, Volume 71, Issue 8, pp. 1054 - 1058
cytochrome P450 | fungicide | resistance | CYP51 | azole | Resistance | Azole | Cytochrome P450 | Fungicide | Agriculture | Life Sciences & Biomedicine | Entomology | Agronomy | Science & Technology | Gene Expression Regulation, Fungal | Sequence Analysis, Protein | Fungi - drug effects | Sterol 14-Demethylase - genetics | Sterol 14-Demethylase - metabolism | Azoles - pharmacology | Fungi - metabolism | Drug Resistance, Fungal | Fungi - genetics | Fungicides, Industrial - pharmacology | Drug resistance in microorganisms | Pathogenic microorganisms | Fungicides | Cytochrome P-450 | Fungi | Pest control | Resistance to control | Crops | Pesticides | Index Medicus
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2. Full Text Fungal echinocandin resistance
by Walker, Louise A and Gow, Neil A.R and Munro, Carol A
Fungal genetics and biology, ISSN 1087-1845, 02/2010, Volume 47, Issue 2, pp. 117 - 126
Candida albicans | Antifungals | Glucan | Chitin | Aspergillus fumigatus | Fungal cell wall | Genetics & Heredity | Life Sciences & Biomedicine | Mycology | Science & Technology | Antifungal Agents - pharmacology | Aspergillus fumigatus - drug effects | Humans | Drug Resistance, Fungal - physiology | Candida albicans - metabolism | Drug Resistance, Fungal - genetics | Aspergillus fumigatus - genetics | Candida albicans - growth & development | Antifungal Agents - therapeutic use | Candida albicans - genetics | Biofilms | Candida albicans - drug effects | Cell Wall - drug effects | Genome, Fungal - genetics | Models, Biological | Cell Wall - metabolism | Mycoses - drug therapy | Echinocandins - therapeutic use | Aspergillus fumigatus - metabolism | Mycoses - immunology | Echinocandins - pharmacology | Enzymes | Polyketides | Enzyme inhibitors | Antifungal agents | Physiological aspects | Plant metabolites | Index Medicus
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3. Full Text A LysM Receptor-like Kinase Plays a Critical Role in Chitin Signaling and Fungal Resistance in Arabidopsis
by Jinrong Wan and Xue-Cheng Zhang and David Neece and Katrina M. Ramonell and Steve Clough and Sung-yong Kim and Minviluz G. Stacey and Gary Stacey
The Plant cell, ISSN 1040-4651, 2/2008, Volume 20, Issue 2, pp. 471 - 481
Pathogens | Legumes | Receptors | Inoculation | Reverse transcriptase polymerase chain reaction | Complementary DNA | Chitin | Plants | Genetic mutation | Plant cells | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Arabidopsis Proteins - genetics | Oligonucleotide Array Sequence Analysis | Plant Proteins - physiology | Transcriptional Activation | Signal Transduction - genetics | Ascomycota - growth & development | Reverse Transcriptase Polymerase Chain Reaction | Genetic Complementation Test | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Oligosaccharides - pharmacology | Arabidopsis - microbiology | Plant Proteins - genetics | Bacteria - growth & development | Gene Expression Regulation, Plant - drug effects | Oligosaccharides - chemistry | Chitin - metabolism | Fabaceae - metabolism | Signal Transduction - physiology | Plant Proteins - metabolism | Fabaceae - genetics | Mutation | Fabaceae - microbiology | Arabidopsis thaliana | Infection | Genetic aspects | Health aspects | Index Medicus
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4. Full Text Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction
by Nishikawa, Joy L and Boeszoermenyi, Andras and Vale-Silva, Luis A and Torelli, Riccardo and Posteraro, Brunella and Sohn, Yoo-Jin and Ji, Fei and Gelev, Vladimir and Sanglard, Dominique and Sanguinetti, Maurizio and Sadreyev, Ruslan I and Mukherjee, Goutam and Bhyravabhotla, Jayaram and Buhrlage, Sara J and Gray, Nathanael S and Wagner, Gerhard and Naar, Anders M and Arthanari, Haribabu
Nature (London), ISSN 0028-0836, 02/2016, Volume 530, Issue 7591, pp. 485 - 489
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fluconazole - pharmacology | Mediator Complex - metabolism | Transcriptional Activation - drug effects | Thiourea - pharmacology | Candidiasis - microbiology | Trans-Activators - chemistry | Ketoconazole - pharmacology | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Fungal - drug effects | Mediator Complex - chemistry | Drug Resistance, Multiple, Fungal - drug effects | Candidiasis - drug therapy | Protein Binding - drug effects | Nuclear Magnetic Resonance, Biomolecular | Binding Sites - drug effects | Antifungal Agents - pharmacology | Protein Structure, Tertiary | Hydrazines - pharmacology | Drug Resistance, Fungal - drug effects | Hydrazines - pharmacokinetics | Models, Molecular | Thiourea - pharmacokinetics | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Candida glabrata - metabolism | Transcription Factors - metabolism | Up-Regulation - drug effects | Animals | Saccharomyces cerevisiae Proteins - metabolism | Trans-Activators - metabolism | Mice | Candida glabrata - genetics | Thiourea - analogs & derivatives | Candida glabrata - drug effects | Fungal Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Prevention | Drug resistance in microorganisms | Gene mutations | Yeast fungi | Physiological aspects | Genetic aspects | Research | Fungi | Transcription factors | Genes | Mutation | Fungal infections | RNA polymerase | Drug resistance | Urogenital system | Index Medicus
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5. Full Text Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance
by Healey, Kelley R and Zhao, Yanan and Perez, Winder B and Lockhart, Shawn R and Sobel, Jack D and Farmakiotis, Dimitrios and Kontoyiannis, Dimitrios P and Sanglard, Dominique and Taj-Aldeen, Saad J and Alexander, Barbara D and Jimenez-Ortigosa, Cristina and Shor, Erika and Perlin, David S
Nature communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, pp. 11128 - 11128
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Kidney - pathology | Drug Resistance, Multiple - drug effects | Humans | Colony Count, Microbial | Candidiasis - microbiology | Antifungal Agents - therapeutic use | Candidiasis - drug therapy | Gene Deletion | Genes, Fungal | Echinocandins - pharmacology | Disease Models, Animal | Antifungal Agents - pharmacology | Drug Resistance, Multiple - genetics | Kidney - drug effects | Drug Resistance, Fungal - drug effects | Genotype | Drug Resistance, Fungal - genetics | Mutation - genetics | Kidney - microbiology | Phenotype | Animals | Candida glabrata - isolation & purification | Echinocandins - therapeutic use | Mice | Candida glabrata - genetics | Index Medicus
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6. Full Text A nuclear receptor-like pathway regulating multidrug resistance in fungi
by Thakur, Jitendra K and Arthanari, Haribabu and Yang, Fajun and Pan, Shih-Jung and Fan, Xiaochun and Breger, Julia and Frueh, Dominique P and Gulshan, Kailash and Li, Darrick K and Mylonakis, Eleftherios and Struhl, Kevin and Moye-Rowley, W. Scott and Cormack, Brendan P and Wagner, Gerhard and Näär, Anders M
Nature (London), ISSN 0028-0836, 04/2008, Volume 452, Issue 7187, pp. 604 - 609
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Action of physical and chemical agents | Biological and medical sciences | Microbiology | Mycology | Fungal Proteins - chemistry | Multigene Family | Receptors, Steroid - metabolism | Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae - drug effects | Trans-Activators - chemistry | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Antifungal Agents - metabolism | Trans-Activators - genetics | Gene Expression Regulation, Fungal - genetics | Xenobiotics - metabolism | Mediator Complex | Genes, Fungal - genetics | Antifungal Agents - pharmacology | Protein Structure, Tertiary | Drug Resistance, Fungal - genetics | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Candida glabrata - metabolism | DNA-Binding Proteins - chemistry | Transcription Factors - metabolism | Animals | Saccharomyces cerevisiae Proteins - metabolism | Trans-Activators - metabolism | Transcription, Genetic - genetics | Candida glabrata - genetics | Candida glabrata - drug effects | Fungal Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Biomedical research | Fungal infections | Drug resistance | Molecular biology | Binding sites | Index Medicus
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7. Full Text Antifungal Drug Resistance: Mechanisms, Epidemiology, and Consequences for Treatment
by Pfaller, Michael A., MD
The American journal of medicine, ISSN 0002-9343, 2012, Volume 125, Issue 1, pp. S3 - S13
Internal Medicine | Antifungal resistance | Echinocandins | Azoles | Clinical breakpoint | Candida glabrata | Epidemiologic cutoff | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antifungal Agents - pharmacology | Candidiasis - genetics | Gene Expression Regulation, Fungal | Up-Regulation | Drug Resistance, Fungal - drug effects | Humans | Fungal Proteins - genetics | Candidiasis - microbiology | Antifungal Agents - therapeutic use | Point Mutation | Furin - genetics | Time Factors | Candidiasis - drug therapy | Candida glabrata - isolation & purification | Female | Drug Therapy, Combination | Child | Microbial Sensitivity Tests - methods | Candida glabrata - drug effects | Fungal Proteins - metabolism | Glucosyltransferases - genetics | Research | Drug resistance | Health aspects | Antifungal agents | Fungal infections | Epidemiology | Medical treatment | Breakpoints | Enzymes | Pathogens | Prophylaxis | Antimicrobial agents | Data processing | Infection | azoles | Minimum inhibitory concentration | Point mutation | echinocandins | Candidemia | Index Medicus | Abridged Index Medicus
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