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Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7605, pp. 129 - 132
The epidermal growth factor receptor (EGFR)-directed tyrosine kinase inhibitors (TKIs) gefitinib, erlotinib and afatinib are approved treatments for non-small... 
CELL LUNG-CANCER | EGFR KINASE | GROWTH-FACTOR RECEPTOR | TARGETED THERAPIES | GEFITINIB | ACTIVATION | MECHANISM | MULTIDISCIPLINARY SCIENCES | MUTATIONS | AZD9291 | Lung Neoplasms - drug therapy | Drug Resistance, Multiple - drug effects | Protein Conformation - drug effects | ErbB Receptors - genetics | Lung Neoplasms - pathology | Antineoplastic Agents - pharmacology | Benzeneacetamides - pharmacology | Mutant Proteins - antagonists & inhibitors | Disease Models, Animal | Allosteric Regulation - drug effects | Carcinoma, Non-Small-Cell Lung - pathology | Drug Resistance, Multiple - genetics | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Lung Neoplasms - enzymology | Allosteric Site - drug effects | Mutant Proteins - genetics | Cetuximab - pharmacology | Mutant Proteins - metabolism | Drug Synergism | Drug Resistance, Neoplasm - genetics | Animals | ErbB Receptors - chemistry | Mutant Proteins - chemistry | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Protein Multimerization - drug effects | Drug Resistance, Neoplasm - drug effects | Studies | Phosphorylation | Nuclear magnetic resonance--NMR | Epidermal growth factor | Mutation | Kinases | Enzyme kinetics | Tumors
Journal Article
Journal Article
ACS Nano, ISSN 1936-0851, 02/2013, Volume 7, Issue 2, pp. 994 - 1005
Journal Article
Cancer Research, ISSN 0008-5472, 10/2010, Volume 70, Issue 20, pp. 7981 - 7991
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2018, Volume 13, Issue 3, p. e0193977
Background Multiple drug resistant (MDR) intra-abdominal infections (IAls) are associated with notable direct and societal costs. As previous studies have not... 
ORGANISMS | IMPACT | BACTERIA | RISK-FACTORS | MANAGEMENT | MULTIDISCIPLINARY SCIENCES | CLINICAL CHARACTERISTICS | OUTCOMES | ANTIMICROBIAL RESISTANCE | KLEBSIELLA-PNEUMONIAE | Drug resistance in microorganisms | Care and treatment | Analysis | Abscess | Research | Medical care, Cost of | Abdomen
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 9, pp. 2780 - 2790
Abstract Co-delivery of siRNA and chemotherapeutic agents has been developed to combat multidrug resistance in cancer therapy. Recently, we developed a series... 
Advanced Basic Science | Dentistry | QDs | β-CD | Co-delivery | siRNA | Doxorubicin | Multidrug resistance | SiRNA | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | MODULATORS | MECHANISMS | DRUG-RESISTANCE | CANCER | P-GLYCOPROTEIN | NANOPARTICLES | MDR1 | THERAPY | beta-CD | INHIBITORS | EXPRESSION | RNA, Small Interfering - genetics | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Adsorption - drug effects | Cell Tracking - methods | Flow Cytometry | Time Factors | Gene Expression Regulation, Neoplastic - drug effects | Gene Transfer Techniques | Microscopy, Electron, Transmission | Drug Resistance, Multiple - genetics | Intracellular Space - drug effects | Spectrometry, Fluorescence | Static Electricity | Cell Shape - drug effects | Particle Size | Microscopy, Confocal | Drug Resistance, Neoplasm - genetics | Quantum Dots | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Intracellular Space - metabolism | ATP Binding Cassette Transporter, Sub-Family B | HeLa Cells | Drug Delivery Systems - methods | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Drug resistance in microorganisms | Chemotherapy | Anthracyclines | Biological products | Messenger RNA | Genes | Fluorescence | Cyclodextrins | Cancer
Journal Article