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Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2018, Volume 90, Issue 18, pp. 11078 - 11085
The exploration of single cells reveals cell heterogeneity and biological principle of cellular metabolism. Although a number of mass spectrometry (MS) based... 
CHEMISTRY, ANALYTICAL | MANIPULATION | EXTRACTION | DATABASE | ABLATION | CLASSIFICATION | LEUKEMIA | TISSUES | IONIZATION | CANCER | ACTIVE METABOLITE | Single-Cell Analysis - instrumentation | Tandem Mass Spectrometry - instrumentation | Drug Screening Assays, Antitumor - instrumentation | Humans | Metabolome | Metabolomics - instrumentation | HeLa Cells | Equipment Design
Journal Article
Lab On a Chip, ISSN 1473-0197, 01/2016, Volume 16, Issue 3, pp. 497 - 505
Here we describe a robust, microfluidic technique to generate and analyze 3D tumor spheroids, which resembles tumor microenvironment and can be used as a more... 
Drugs | Screening | Droplets | Devices | Microfluidics | Spheroids | Three dimensional | Tumors
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e108283
3-dimensional (3D) culture models have the potential to bridge the gap between monolayer cell culture and in vivo studies. To benefit anti-cancer drug... 
BREAST-CANCER | TARGET | CELLS | IN-VITRO | MODELS | MULTIDISCIPLINARY SCIENCES | TISSUE | FIBROBLASTS | Human Umbilical Vein Endothelial Cells | Tubulin Modulators - pharmacology | Coculture Techniques | Epithelial Cells - drug effects | Humans | Receptor, ErbB-2 - metabolism | Male | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Cell Culture Techniques - methods | Antineoplastic Agents - toxicity | Dose-Response Relationship, Drug | Protein Processing, Post-Translational - drug effects | Female | Antineoplastic Agents - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Spheroids, Cellular - drug effects | Phosphorylation - drug effects | Antineoplastic Agents - classification | Tubulin Modulators - toxicity | Drug Screening Assays, Antitumor - methods | ErbB Receptors - antagonists & inhibitors | Cell Culture Techniques - instrumentation | Breast - cytology | Cells, Cultured | High-Throughput Screening Assays | Drug Screening Assays, Antitumor - instrumentation | Breast Neoplasms - pathology | Fibroblasts - drug effects | Cell Line, Tumor | Protein Kinase Inhibitors - toxicity | Protein Kinase Inhibitors - pharmacology | Miniaturization | Care and treatment | Diagnosis | Drug discovery | Cells | Cancer | Monomolecular films | Drugs | Cell culture | Toxicity | Epithelial cells | High-throughput screening | Cytotoxicity | Oncology | Kinases | Cancer therapies | Epidermal growth factor | Fibroblasts | Biocompatibility | Medical research | Sensitivity analysis | Epidermal growth factor receptors | Cultures | Breast cancer | FDA approval | Gene expression | Spheroids | Endothelial cells | Studies | Screening | Sensitivity | Inhibitors | Cell lines | Monolayers | In vivo methods and tests | Three dimensional models
Journal Article