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PloS one, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, pp. e0155772 - e0155772
Journal Article
Nature medicine, ISSN 1546-170X, 11/2017, Volume 23, Issue 12, pp. 1424 - 1435
Human liver cancer research currently lacks in vitro models that can faithfully recapitulate the pathophysiology of the original tumor. We recently described a... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Cell Proliferation | Primary Cell Culture - methods | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Male | Antineoplastic Agents - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - isolation & purification | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Bile Duct Neoplasms - genetics | Tumor Cells, Cultured | Bile Duct Neoplasms - drug therapy | Precision Medicine | Drug Screening Assays, Antitumor - methods | Organoids - pathology | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Mice, SCID | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Carcinoma, Hepatocellular - pathology | Cholangiocarcinoma - genetics | Mice, Inbred NOD | Mice | Bile Duct Neoplasms - pathology | Cell culture | Liver cancer | Development and progression | Usage | Models | Research | Propagation | Liver | Extracellular signal-regulated kinase | Hepatocellular carcinoma | Pharmacology | Gene expression | Tissues | Drug screening | Chemical compounds | Metastases | Screening | Utilities | Biomedical materials | Hepatocytes | Organoids | Xenografts | Biomarkers | In vivo methods and tests | Cholangiocarcinoma | Tumors | Cancer | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e103817 - e103817
Journal Article
PloS one, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e45571 - e45571
.... Using cancer cell-based survivin-reporter systems (US 7,569,221 B2) via high throughput screening (HTS... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasms - metabolism | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Promoter Regions, Genetic - drug effects | Tumor Suppressor Protein p53 - genetics | Antineoplastic Agents - toxicity | Proto-Oncogene Proteins c-bcl-2 - metabolism | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Benzodioxoles - toxicity | Neoplasms - genetics | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Benzodioxoles - chemistry | Gene Expression Regulation, Neoplastic - drug effects | DNA Topoisomerases, Type I - metabolism | Tumor Suppressor Protein p53 - metabolism | Antineoplastic Agents - chemistry | Mice, SCID | X-Linked Inhibitor of Apoptosis Protein - genetics | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Maximum Tolerated Dose | Animals | High-Throughput Screening Assays | Tumor Burden - drug effects | Indolizines - chemistry | Mice, Nude | Myeloid Cell Leukemia Sequence 1 Protein | Indolizines - toxicity | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Benzodioxoles - pharmacology | Indolizines - pharmacology | Drug Screening Assays, Antitumor | Antimitotic agents | Physiological aspects | Genetic aspects | Research | Survivin | Antineoplastic agents | Drug therapy | Tumor proteins | Tumors | Animal models | Gemcitabine | p53 Protein | Genes | Radiation | Colorectal cancer | Clinical trials | High-throughput screening | XIAP protein | Body weight loss | Metastasis | Cancer therapies | Doxorubicin | Anticancer properties | Oxaliplatin | Xenografts | Cell cycle | Fibroblasts | Inhibition | Deoxyribonucleic acid--DNA | Medical research | DNA topoisomerase | Cell division | Topotecan | Pharmacology | Lead compounds | Regression analysis | Gene expression | Cisplatin | Mcl-1 protein | Gene silencing | Irinotecan | Chemotherapy | Stem cells | Radiation tolerance | Antitumor activity | In vivo methods and tests | Laboratory animals | Prostate cancer | Cancer | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Cancer science, ISSN 1347-9032, 07/2014, Volume 105, Issue 7, pp. 870 - 874
Journal Article