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Advanced Drug Delivery Reviews, ISSN 0169-409X, 03/2019, Volume 143, pp. 97 - 114
Journal Article
Pharmacogenomics, ISSN 1462-2416, 02/2011, Volume 12, Issue 2, pp. 215 - 233
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 03/2012, Volume 25, Issue 3, pp. 513 - 531
Journal Article
Drug metabolism and disposition: the biological fate of chemicals, ISSN 0090-9556, 2014, Volume 42, Issue 11, pp. 1914 - 1920
Antibody-drug conjugates (ADCs) are a class of therapeutics that are designed to deliver potent small-molecule drugs selectively to cells that express a... 
Tissue Distribution | Immunoconjugates - pharmacokinetics | Immunoconjugates - therapeutic use | Animals | Drug Stability | Humans
Journal Article
CANCER CHEMOTHERAPY AND PHARMACOLOGY, ISSN 0344-5704, 07/2014, Volume 74, Issue 1, pp. 63 - 75
The absorption, distribution, metabolism, and excretion of the hedgehog pathway inhibitor sonidegib (LDE225) were determined in healthy male subjects. Six... 
ACIDIC DRUGS | Absorption | ONCOLOGY | Distribution | Excretion Hedgehog | PHARMACOLOGY & PHARMACY | Sonidegib (LDE225) | Metabolism | ACCELERATOR MASS-SPECTROMETRY | BINDING | CANCER | HEDGEHOG
Journal Article
Xenobiotica, ISSN 0049-8254, 01/2019, Volume 49, Issue 1, pp. 43 - 53
1. The absorption, distribution, metabolism, and excretion of CC-223 were studied following a single oral dose of [ 14 C]CC-223 to rats (3 mg/kg; 90 μCi/kg),... 
Accelerator mass spectrometry | mTOR kinase inhibitor | ADME | species comparison | DRUG | SAFETY | ACCELERATOR MASS-SPECTROMETRY | BALANCE | THROUGHPUT | PATHWAY | PHARMACOLOGY & PHARMACY | EXPERIENCE | TOXICOLOGY
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2015, Volume 43, Issue 2, pp. 273 - 283
Journal Article