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1. Transdermal and intradermal delivery of therapeutic agents
: application of physical technologies
by Banga, Ajay K
2011, ISBN 1439805091, xv, 285
"Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined... 
Iontophoresis | Electroporation | Transdermal medication | Injections, Intradermal
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2. Full Text Reduced Exposure to Calcineurin Inhibitors in Renal Transplantation
by Ekberg, Henrik and Tedesco-Silva, Helio and Demirbas, Alper and Vítko, Štefan and Nashan, Björn and Gürkan, Alp and Margreiter, Raimund and Hugo, Christian and Grinyó, Josep M and Frei, Ulrich and Vanrenterghem, Yves and Daloze, Pierre and Halloran, Philip F and ELITE Symphony Study and ELITE-Symphony Study and Enheten för forskning kring njurfunktion och njursjukdom and Lund University and Renal Research Unit and Lunds universitet
The New England Journal of Medicine, ISSN 0028-4793, 12/2007, Volume 357, Issue 25, pp. 2562 - 2575
This study examines the toxicity of immunosuppressive regimens in renal-transplant recipients. A regimen containing mycophenolate mofetil, daclizumab, low-dose... 
MULTICENTER TRIAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE MICROEMULSION | EFFICACY | KIDNEY-TRANSPLANTATION | IMMUNOSUPPRESSION | ALLOGRAFT RECIPIENTS | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | NEPHROTOXICITY | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Enzyme Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized | Calcineurin Inhibitors | Treatment Failure | Adult | Diabetes Mellitus - etiology | Female | Drug Therapy, Combination | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Glomerular Filtration Rate | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Kidney Transplantation | Immunoglobulin G - administration & dosage | Opportunistic Infections | Sirolimus - administration & dosage | Mycophenolic Acid - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Cyclosporine - administration & dosage | Immunosuppressive Agents - adverse effects | Aged | Adrenal Cortex Hormones - administration & dosage | Transplantation | Corticosteroids | Kidneys | Research | Health aspects | Immunosuppressive agents | Medical research | Immunology | Inhibitor drugs | Transplants & implants | Toxicity | Inhibidors enzimàtics | Posologia | Ús terapèutic | Corticosteroides | Rebuig (Biologia) | Posology | Therapeutic use | Immunosupressive agents | Graft rejection | Trasplantament renal | Enzyme inhibitors | Adrenocortical hormones | Immunosupressors | Kidney transplantation | Tacrolimus: administration & dosage | Medical and Health Sciences | Graft Rejection: prevention & control | Immunoglobulin G: administration & dosage | Medicin och hälsovetenskap | Mycophenolic Acid: administration & dosage | Antibodies | Klinisk medicin | Monoclonal: administration & dosage | Prednisone: administration & dosage | Adrenal Cortex Hormones: administration & dosage | Immunosuppressive Agents: administration & dosage | Mycophenolic Acid: analogs & derivatives | Sirolimus: administration & dosage | Cyclosporine: administration & dosage | Calcineurin: antagonists & inhibitors | Diabetes Mellitus: etiology | Urologi och njurmedicin | Sirolimus: adverse effects | Adrenal Cortex Hormones: therapeutic use | Enzyme Inhibitors: administration & dosage | Immunosuppressive Agents: adverse effects | Clinical Medicine | Immunosuppressive Agents: therapeutic use | Urology and Nephrology
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3. Topical and transdermal drug delivery
: principles and practice
by Benson, Heather A. E and Watkinson, Adam C
2012, 1. Aufl., ISBN 9780470450291, xv, 446
"By understanding the mechanisms by which compounds cross the skin, it becomes possible to devise means for improving drug delivery. Providing an overview of... 
Skin absorption | Drug delivery systems | Transdermal medication | Pharmacology | MEDICAL
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4. Full Text Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial
by Dahlöf, Björn and Sever, Peter S and Poulter, Neil R and Wedel, Hans and Beevers, D Gareth and Caulfield, Mark and Collins, Rory and Kjeldsen, Sverre E and Kristinsson, Arni and McInnes, Gordon T and Mehlsen, Jesper and Nieminen, Markku and O'Brien, Eoin and Östergren, Jan and ASCOT Investigators and Hjärt-kärlinstitutionen and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Cardiovascular Institute and Sahlgrenska Academy
The Lancet, ISSN 0140-6736, 09/2005, Volume 366, Issue 9489, pp. 895 - 906
The apparent shortfall in prevention of coronary heart disease (CHD) noted in early hypertension trials has been attributed to disadvantages of the diuretics... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | MANAGEMENT | MORBIDITY | DISEASE | GUIDELINES | DOUBLE-BLIND | CALCIUM-ANTAGONISTS | HYPERTENSION | INTERVENTION | Calcium Channel Blockers - adverse effects | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antihypertensive Agents - administration & dosage | Bendroflumethiazide - administration & dosage | Hypertension - drug therapy | Male | Perindopril - administration & dosage | Sodium Chloride Symporter Inhibitors - administration & dosage | Diuretics | Adrenergic beta-Antagonists - adverse effects | Adult | Female | Blood Pressure - drug effects | Atenolol - administration & dosage | Drug Therapy, Combination | Amlodipine - administration & dosage | Adrenergic beta-Antagonists - administration & dosage | Risk Factors | Amlodipine - adverse effects | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Antihypertensive Agents - adverse effects | Coronary Disease - prevention & control | Calcium Channel Blockers - administration & dosage | Atenolol - adverse effects | Hypertension - complications | Aged | Hypertension | Antihypertensive drugs | Evaluation | Dosage and administration | Drug therapy | Prevention | Drug therapy, Combination | Health aspects | Coronary heart disease | Risk factors | Studies | Drugs | Cardiovascular disease | Medical treatment | Myocardial infarction | Heart attacks | Clinical trials | Family medical history | Blood | Randomization | Motivation | Blood pressure | Heart diseases | Antihypertensive agents | Cerebral infarction | Stroke | Fasting | Mortality | Diabetes mellitus | Health risks | Triglycerides | Metabolism | Risk analysis | Atenolol | Fatal | Patients | Coronary artery disease | Cholesterol | Heart rate | Infarction | Diabetes | Cardiovascular diseases | Health risk assessment | Potassium | Amlodipine/administration & dosage/adverse effects | Bendroflumethiazide/administration & dosage | Cardiovascular Diseases/prevention & control | Perindopril/administration & dosage | MEDICIN OCH HÄLSOVETENSKAP | Atenolol/administration & dosage/adverse effects | Combination | Antihypertensive Agents/administration & dosage/adverse effects | Angiotensin-Converting Enzyme Inhibitors/administration & dosage | MEDICAL AND HEALTH SCIENCES | Coronary Disease/prevention & control | Drug Therapy | Adrenergic beta-Antagonists/administration & dosage/adverse effects | Blood Pressure/drug effects | Hypertension/complications/drug therapy | Calcium Channel Blockers/administration & dosage/adverse effects | Sodium Chloride Symporter Inhibitors/administration & dosage
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5. Advanced drug delivery reviews
Advanced drug delivery reviews, ISSN 0169-409X, 1987
Drugs | Administration | Periodicals
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6. Full Text Effect of Evolocumab or Ezetimibe Added to Moderate- or High-Intensity Statin Therapy on LDL-C Lowering in Patients With Hypercholesterolemia: The LAPLACE-2 Randomized Clinical Trial
by Robinson, Jennifer G and Nedergaard, Bettina S and Rogers, William J and Fialkow, Jonathan and Neutel, Joel M and Ramstad, David and Somaratne, Ransi and Legg, Jason C and Nelson, Patric and Scott, Rob and Wasserman, Scott M and Weiss, Robert and LAPLACE-2 Investigators
JAMA, ISSN 0098-7484, 05/2014, Volume 311, Issue 18, pp. 1870 - 1882
IMPORTANCE In phase 2 studies, evolocumab, a fully human monoclonal antibody to PCSK9, reduced LDL-C levels in patients receiving statin therapy. OBJECTIVE To... 
MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | EFFICACY | REDUCTION | SAFETY | TOLERABILITY | SUBTILISIN/KEXIN TYPE 9 | ACUTE CORONARY SYNDROMES | MONOCLONAL-ANTIBODY | DYSLIPIDEMIA | AMG 145 | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Dyslipidemias - drug therapy | Double-Blind Method | Pyrimidines - administration & dosage | Simvastatin - administration & dosage | Humans | Middle Aged | Ezetimibe | Rosuvastatin Calcium | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Fluorobenzenes - administration & dosage | Hypercholesterolemia - drug therapy | Atorvastatin Calcium | Azetidines - therapeutic use | Pyrroles - administration & dosage | Anticholesteremic Agents - administration & dosage | Heptanoic Acids - administration & dosage | Female | Aged | Drug Therapy, Combination | Sulfonamides - administration & dosage | Clinical trials | Care and treatment | Pharmacology | Hypercholesterolemia | Research | Analysis | Side effects | Monoclonal antibodies | Drug therapy | Low density lipoprotein | Statins | Cholesterol | Life Sciences | Human health and pathology
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7. Electrically assisted transdermal and topical drug delivery
by Banga, Ajay K
1998, 1, Taylor & Francis series in pharmaceutical sciences, ISBN 9780748406876, xi, 172
Percutaneous absorption is the development of transdermal drug delivery patches, as well as the treatment of skin disorders. The skin permeability of most... 
Iontophoresis | Electroporation | Electro-osmosis | Transdermal medication | Other branches of medicine | Skin absorption
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8. Full Text Geneva Cocktail for Cytochrome P450 and P‐Glycoprotein Activity Assessment Using Dried Blood Spots
by Bosilkovska, M and Samer, C F and Déglon, J and Rebsamen, M and Staub, C and Dayer, P and Walder, B and Desmeules, J A and Daali, Y
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2014, Volume 96, Issue 3, pp. 349 - 359
The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and... 
P4502B6 ACTIVITY | VORICONAZOLE | LC-MS/MS | SINGLE-POINT | ORAL MIDAZOLAM | VOLUNTEERS | IN-VIVO | PHARMACOLOGY & PHARMACY | DRUG-METABOLIZING-ENZYMES | KAROLINSKA COCKTAIL | BUPROPION HYDROXYLATION | Predictive Value of Tests | Pharmaceutical Preparations - blood | Caffeine - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Dried Blood Spot Testing | Humans | Omeprazole - blood | Bupropion - blood | Midazolam - administration & dosage | Substrate Specificity | Male | Chromatography, High Pressure Liquid | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Coffee | Terfenadine - administration & dosage | Caffeine - pharmacokinetics | Feasibility Studies | Enzyme Inhibitors - administration & dosage | Young Adult | Chromatography, Reverse-Phase | Tandem Mass Spectrometry | Capsules | Spectrometry, Mass, Electrospray Ionization | Flurbiprofen - administration & dosage | Adult | Dextromethorphan - pharmacokinetics | Terfenadine - blood | ATP-Binding Cassette, Sub-Family B, Member 1 - blood | Pharmaceutical Preparations - administration & dosage | Terfenadine - pharmacokinetics | Bupropion - pharmacokinetics | Flurbiprofen - pharmacokinetics | Cytochrome P-450 Enzyme System - blood | Administration, Oral | Isoenzymes | Caffeine - blood | Omeprazole - administration & dosage | Terfenadine - analogs & derivatives | Omeprazole - pharmacokinetics | Carbonated Beverages | Midazolam - pharmacokinetics | Bupropion - administration & dosage | Dextromethorphan - blood | Flurbiprofen - blood | Phenotype | Pilot Projects | Midazolam - blood | Dextromethorphan - administration & dosage | Usage | Glycoproteins | Liquid chromatography | Research | Pharmacokinetics | Cytochrome P-450 | Index Medicus | Abridged Index Medicus
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9. Full Text Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis
by Cipriani, Andrea, Dr and Zhou, Xinyu, PhD and Del Giovane, Cinzia, PhD and Hetrick, Sarah E, DPsych and Qin, Bin, MD and Whittington, Craig, PhD and Coghill, David, Prof and Zhang, Yuqing, MD and Hazell, Philip, Prof and Leucht, Stefan, Prof and Cuijpers, Pim, Prof and Pu, Juncai, MD and Cohen, David, PhD and Ravindran, Arun V, Prof and Liu, Yiyun, MD and Michael, Kurt D, Prof and Yang, Lining, MD and Liu, Lanxiang, MD and Xie, Peng, Prof
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10047, pp. 881 - 890
Summary Background Major depressive disorder is one of the most common mental disorders in children and adolescents. However, whether to use pharmacological... 
Internal Medicine | TRIALS | MEDICINE, GENERAL & INTERNAL | ACCEPTABILITY | MENTAL-HEALTH-CARE | TRENDS | GUIDELINES | Mianserin - adverse effects | Triazoles - administration & dosage | Triazoles - adverse effects | Humans | Citalopram - adverse effects | Sertraline - adverse effects | Venlafaxine Hydrochloride - adverse effects | Imipramine - administration & dosage | Paroxetine - adverse effects | Mianserin - analogs & derivatives | Paroxetine - administration & dosage | Desipramine - adverse effects | Nortriptyline - administration & dosage | Nortriptyline - adverse effects | Mianserin - administration & dosage | Child | Fluoxetine - adverse effects | Depressive Disorder, Major - drug therapy | Clomipramine - administration & dosage | Duloxetine Hydrochloride - adverse effects | Double-Blind Method | Drug Administration Schedule | Treatment Outcome | Clomipramine - adverse effects | Evidence-Based Medicine | Desipramine - administration & dosage | Randomized Controlled Trials as Topic | Venlafaxine Hydrochloride - administration & dosage | Citalopram - administration & dosage | Confounding Factors (Epidemiology) | Sertraline - administration & dosage | Adolescent | Amitriptyline - adverse effects | Bayes Theorem | Fluoxetine - administration & dosage | Duloxetine Hydrochloride - administration & dosage | Antidepressive Agents - administration & dosage | Antidepressive Agents - adverse effects | Research Design | Amitriptyline - administration & dosage | Imipramine - adverse effects | Psychological aspects | Medical colleges | Neurosciences | Drugs and youth | Rankings | Comparative analysis | Child psychopathology | Major depressive disorder | Antidepressants, Tricyclic | Pediatric pharmacology | Mental illness | Studies | Teenagers | Mental depression | Antidepressants | Meta-analysis | Children & youth
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