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Supportive Care in Cancer, ISSN 0941-4355, 7/2015, Volume 23, Issue 7, pp. 1917 - 1923
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 06/2016, Volume 77, pp. 25 - 34
Narrow Therapeutic Index Drugs (NTIDs) are characterized by a small range between therapeutic and toxicological effect. Missing international harmonized... 
Imatinib | Sunitinib | Receptor tyrosine kinase (RTK) | Toxicity | Cell viability | Tyrosine kinase inhibitor (TKI) | Drug safety | Apoptosis | Narrow Therapeutic Index Drug (NTID) | Narrow therapeutic index drug (NTID) | SURVIVAL | MANAGEMENT | VIVO | MEDICINE, LEGAL | PHOSPHORYLATION | SAFETY | Imatinib Narrow Therapeutic Index Drug (NTID) | ANTITUMOR-ACTIVITY | SU11248 | TYROSINE KINASE INHIBITOR | PHARMACOLOGY & PHARMACY | TOXICOLOGY | GROWTH-FACTOR | CARCINOMA | Phosphorylation | Apoptosis - drug effects | Humans | Antineoplastic Agents - administration & dosage | Indoles - administration & dosage | Antineoplastic Agents - toxicity | Dose-Response Relationship, Drug | Pyrroles - administration & dosage | Imatinib Mesylate - administration & dosage | Inhibitory Concentration 50 | Toxicity Tests - methods | Drug and Narcotic Control | Cell Survival - drug effects | Risk Assessment | Drugs, Generic - administration & dosage | Neoplasms - enzymology | Imatinib Mesylate - toxicity | Indoles - toxicity | Organ Specificity | Apoptosis Regulatory Proteins - metabolism | Neoplasms - drug therapy | Protein Kinase Inhibitors - administration & dosage | Animals | Signal Transduction - drug effects | Pyrroles - toxicity | Cell Line, Tumor | Protein Kinase Inhibitors - toxicity | Neoplasms - pathology | Drugs, Generic - toxicity | Proteins | Antimitotic agents | Tyrosine | Antineoplastic agents | Health aspects | Analysis | Generic drugs | Index Medicus
Journal Article
Journal Article
Cancer Science, ISSN 1347-9032, 01/2011, Volume 102, Issue 1, pp. 162 - 165
Journal Article