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Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 08/2016, Volume 97, pp. 95 - 108
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease characterized by progressive loss of motor neurons, gliosis, neuroinflammation... 
SOD1G93A mice | Thioridazine | NADPH oxidase | NOX | Amyotrophic lateral sclerosis | Perphenazine | Microglia | Phenothiazine | DUOX dual oxidase | List of abbreviations ALS amyotrophic lateral sclerosis | WST-1 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt | PBS phosphate buffered saline | HOCl hypochlorous acid | BBB blood brain barrier | WT wild typ | 2-chloroethidium | 2-Cl-E | NOXO1 NADPH oxidase organiser type 1 | CNS central nervous system | DPI diphenyleneiodonium | ethidium | NOX NADPH oxidase | HE hydroethidine | qPCR quantitative polymerase chain reaction | MPO myeloperoxidase | LC/MS/MS Liquid chromatography-tandem mass spectrometry | GM-CSF granulocyte-macrophage colony-stimulating factor | PMA phorbol myristate acetate | TDP 43 TAR DNA binding protein 43 | DMEM Dulbecco's modified Eagle Medium | hydrogen peroxide | DNA deoxyribonucleic acid | ROS reactive oxygen species | superoxide radical anion | SOD superoxide dismutase | HBSS Hank's buffered salt solution | half maximal efficient concentration | 2-hydroxyethidium | NADPH nicotinamide adenine dinucleotide phosphate | NC non-carrier | FBS fetal bovine serum | 2-OH-E | FUS/TLS Fused in Sarcoma/Translocated in Sarcoma | DMSO Dimethylsulfoxide | SURVIVAL | SUPEROXIDE | HYDROETHIDINE | SOD1(G93A) mice | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINAL-CORD | REACTIVE OXYGEN | MOTOR-NEURON DEGENERATION | NOX FAMILY | ENDOCRINOLOGY & METABOLISM | ALS MICE | INHIBITOR | Spinal Cord - drug effects | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Male | NADPH Oxidase 1 - genetics | Thioridazine - administration & dosage | Amyotrophic Lateral Sclerosis - drug therapy | Motor Neurons - pathology | Gene Expression Regulation - drug effects | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | NADPH Oxidase 2 - metabolism | Spinal Cord - pathology | Superoxide Dismutase-1 - genetics | Adult | Female | Aged | Mice | Perphenazine - administration & dosage | NADPH Oxidase 2 - genetics | Superoxide Dismutase-1 - antagonists & inhibitors | Disease Models, Animal | Oxidases | Nervous system diseases | Analysis | Oncology, Experimental | Superoxide | Research | Cancer
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54205 - e54205
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2014, Volume 34, Issue 9, pp. 2023 - 2032
OBJECTIVE—Reactive oxygen species (ROS) act as signaling molecules during angiogenesis; however, the mechanisms used for such signaling events remain unclear.... 
migration | stromal cell-derived factor-1aα | angiogenesis | NADPH oxidase | reactive oxygen species | OXIDATIVE STRESS | ACTIVATION | SUPEROXIDE | MECHANISM | INACTIVATION | NAD(P)H OXIDASE | NOX-FAMILY | PROSTATE-CANCER CELLS | REVERSIBLE OXIDATION | stromal cell-derived factor-1 alpha | PERIPHERAL VASCULAR DISEASE | GROWTH-FACTOR | HEMATOLOGY | Endothelium, Vascular - cytology | Chemokine CXCL12 - physiology | Neovascularization, Physiologic - drug effects | Reactive Oxygen Species - metabolism | Mitogen-Activated Protein Kinase Phosphatases - physiology | Organoselenium Compounds - pharmacology | Gene Knockdown Techniques | Dual-Specificity Phosphatases - physiology | Cattle | Membrane Proteins - physiology | NADPH Oxidases - genetics | Aorta | Isoenzymes - physiology | Oxidation-Reduction | Isoenzymes - genetics | Membrane Proteins - genetics | Mitogen-Activated Protein Kinase 10 - physiology | NADPH Oxidases - antagonists & inhibitors | Antioxidants - pharmacology | Azoles - pharmacology | Hyperglycemia - metabolism | Cell Movement - drug effects | Neovascularization, Physiologic - physiology | Animals | Membrane Proteins - antagonists & inhibitors | Signal Transduction - drug effects | Chemokine CXCL12 - pharmacology | Acetylcysteine - pharmacology | Signal Transduction - physiology | NADPH Oxidases - physiology | Isoenzymes - antagonists & inhibitors | Endothelial Cells - drug effects
Journal Article