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phosphate-buffered saline (63) 63
erk, extracellular-signal-regulated kinase (62) 62
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cercopithecus aethiops (57) 57
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Reactive and Functional Polymers, ISSN 1381-5148, 05/2013, Volume 73, Issue 5, pp. 683 - 689
Nanocomposite hydrogels (NC gels) were synthesized through in situ polymerization of N-isopropylacrylamide (NIPAm) in the hectorite clay suspension made from... 
Cell culture | Dulbecco’s modified Eagle medium | Nanocomposite hydrogel | Hectorite | Mechanical relaxation | Dulbecco's modified Eagle medium | NETWORK CHAIN DENSITY | ADHESIVE | POLYMER SCIENCE | GELS | BEHAVIOR | ENGINEERING, CHEMICAL | CHEMISTRY, APPLIED | CLAY | Polymerization | Nanotechnology
Journal Article
Redox Biology, ISSN 2213-2317, 01/2019, Volume 20, pp. 167 - 181
Monoamine oxidases (MAOs) are located on the outer mitochondrial membrane and are drug targets for the treatment of neurological disorders. MAOs control the... 
Reactive oxygen species | Monoamine oxidase | Neurodegeneration | Autophagy | CLEARANCE | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOPHAGY | REAL-TIME PCR | LYSOSOMES | TYRAMINE | FISSION | MITOCHONDRIAL-DNA DELETIONS | PROTEINS | INHIBITOR
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 08/2016, Volume 97, pp. 95 - 108
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease characterized by progressive loss of motor neurons, gliosis, neuroinflammation... 
SOD1G93A mice | Thioridazine | NADPH oxidase | NOX | Amyotrophic lateral sclerosis | Perphenazine | Microglia | Phenothiazine | DUOX dual oxidase | List of abbreviations ALS amyotrophic lateral sclerosis | WST-1 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt | PBS phosphate buffered saline | HOCl hypochlorous acid | BBB blood brain barrier | WT wild typ | 2-chloroethidium | 2-Cl-E | NOXO1 NADPH oxidase organiser type 1 | CNS central nervous system | DPI diphenyleneiodonium | ethidium | NOX NADPH oxidase | HE hydroethidine | qPCR quantitative polymerase chain reaction | MPO myeloperoxidase | LC/MS/MS Liquid chromatography-tandem mass spectrometry | GM-CSF granulocyte-macrophage colony-stimulating factor | PMA phorbol myristate acetate | TDP 43 TAR DNA binding protein 43 | DMEM Dulbecco's modified Eagle Medium | hydrogen peroxide | DNA deoxyribonucleic acid | ROS reactive oxygen species | superoxide radical anion | SOD superoxide dismutase | HBSS Hank's buffered salt solution | half maximal efficient concentration | 2-hydroxyethidium | NADPH nicotinamide adenine dinucleotide phosphate | NC non-carrier | FBS fetal bovine serum | 2-OH-E | FUS/TLS Fused in Sarcoma/Translocated in Sarcoma | DMSO Dimethylsulfoxide | SURVIVAL | SUPEROXIDE | HYDROETHIDINE | SOD1(G93A) mice | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINAL-CORD | REACTIVE OXYGEN | MOTOR-NEURON DEGENERATION | NOX FAMILY | ENDOCRINOLOGY & METABOLISM | ALS MICE | INHIBITOR | Spinal Cord - drug effects | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Male | NADPH Oxidase 1 - genetics | Thioridazine - administration & dosage | Amyotrophic Lateral Sclerosis - drug therapy | Motor Neurons - pathology | Gene Expression Regulation - drug effects | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | NADPH Oxidase 2 - metabolism | Spinal Cord - pathology | Superoxide Dismutase-1 - genetics | Adult | Female | Aged | Mice | Perphenazine - administration & dosage | NADPH Oxidase 2 - genetics | Superoxide Dismutase-1 - antagonists & inhibitors | Disease Models, Animal | Oxidases | Nervous system diseases | Analysis | Oncology, Experimental | Superoxide | Research | Cancer
Journal Article
Pulmonary Pharmacology & Therapeutics, ISSN 1094-5539, 2015, Volume 33, pp. 66 - 74
Abstract Background Serine proteases act through the proteolytic cleavage of the hemagglutinin (HA) of influenza viruses for the entry of influenza virus into... 
Medical Education | Pulmonary/Respiratory | Airway epithelial cell | Cell culture | Camostat | Serine protease | Influenza | Interleukin | GABEXATE MESILATE | NEUTROPHIL ELASTASE | SODIUM-CHANNEL | RESPIRATORY EPITHELIUM | RESPIRATORY SYSTEM | A VIRUSES | AIRWAY EPITHELIUM | GENE-EXPRESSION | HOST-DEFENSE | PHARMACOLOGY & PHARMACY | SENDAI VIRUS | TRYPSIN-LIKE PROTEASE | Virus Replication - drug effects | Trachea - cytology | Epithelial Cells - drug effects | Humans | Middle Aged | Cells, Cultured | Gabexate - pharmacology | Gabexate - analogs & derivatives | Male | Trachea - virology | Animals | Aprotinin - pharmacology | Influenza A Virus, H1N1 Subtype - isolation & purification | Influenza A Virus, H3N2 Subtype - isolation & purification | Epithelial Cells - virology | Dogs | Madin Darby Canine Kidney Cells | Female | Influenza, Human - virology | Aged | RNA, Viral - metabolism | Influenza, Human - drug therapy | Serine Proteinase Inhibitors - pharmacology | Influenza viruses | Medical colleges | Cytokines | Protease inhibitors | Serine | Lectins | Thrombin | Health aspects | Medicine, Preventive | Preventive health services | SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis | COPD, chronic obstructive pulmonary disease | F-12, Ham's F-12 medium | ELISA, enzyme-linked immunosorbent assay | SARS-CoV, severe acute respiratory syndrome coronavirus | DMEM, Dulbecco's modified Eagle's medium | PVDF, polyvinylidene difluoride | ANOVA, analysis of variance | TMPRSS, transmembrane protease serine S1 member | MEM, Eagle's minimum essential medium | HAT, human trypsin-like protease | RT, room temperature | TCID, tissue culture infective dose | IFN, interferon | PBS-T, phosphate buffered saline with Tween® 20 | TNF, tumor necrosis factor | LDH, lactate dehydrogenase | PBS, phosphate buffered saline | MDCK, Madin Darby Canine Kidney | KIU, Kallikrein Inhibitor Unit | MOI, multiplicity of infection | HA, hemagglutinin | IL, interleukin | DF-12, mixture of Dulbecco's modified Eagle's medium-Ham's F-12 medium | AEBSF, 4-(2-aminoethyl)-benzenesulfonyl fluoride | LPS, lipopolysaccharide | USG, Ultroser G | CLEIA, chemiluminescent enzyme immunoassay
Journal Article
Autophagy, ISSN 1554-8627, 03/2015, Volume 11, Issue 3, pp. 503 - 515
Autophagy is an essential component of host innate and adaptive immunity. Viruses have developed diverse strategies for evading or utilizing autophagy for... 
RNAi, RNA interference | dsRNA, double-stranded RNA | mAb, monoclonal antibody | TSC, tuberous sclerosis complex | Gg, Gallus gallus (chicken) | HE-IBDV, heat-inactivated IBDV | DMEM, Dulbecco's modified Eagle's medium | HSP90AA1, heat shock protein 90 kDa alpha (cytosolic), class A member 1 | ANOVA, analysis of variance | EIF2AK2, eukaryotic translation initiation factor 2-alpha kinase 2 | 50 | HSP90AA1 | autophagy | GST, glutathione S-transferase | IBDV, infectious bursal disease virus | EBSS, Earle's balanced salt solution | EIF2S1, eukaryotic translation initiation factor 2, subunit 1 alpha | BECN1, Beclin 1, autophagy-related | MTOR, mechanistic target of rapamycin (serine/threonine kinase) | IgG, immunoglobulin G | Ni-NTA, nickel-nitrilotriacetic acid | SQSTM1, sequestosome 1 | LPS, lipopolysaccharide | shRNA, short hairpin RNA | PAMP, pathogen-associated molecular patterns | 50% tissue culture infectious doses | PI3K, phosphoinositide 3-kinase | cDNA, complementary DNA | eGFP, enhanced green fluorescent protein | HSV-1, herpes simplex virus 1 | hpi, hours post-infection | MAP1LC3/LC3, microtubule-associated protein 1 light chain 3 | SDS, sodium dodecyl sulfate | PBS, phosphate-buffered saline | SVP, subviral particle | ATG5, autophagy-related 5 | PRR, pattern recognition receptors | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | CoIP, coimmunoprecipitation | VP, viral protein | BCA, bicinchoninic acid | Hs, Homo sapiens (human) | TCID | TLR, toll-like receptors | siRNA, small interfering RNA | AKT-MTOR pathway | viral protein VP2 | MOI, multiplicity of infection | GOPC, golgi-associated PDZ and coiled-coil motif containing | ER, endoplasmic reticulum | avibirnavirus | Viral protein VP2 | Autophagy | Avibirnavirus | PROTEIN | toll-like receptors | sequestosome 1 | nickel-nitrilotriacetic acid | phosphate-buffered saline | CELL BIOLOGY | class A member 1 | PI3K | autophagy-related | infectious bursal disease virus | dsRNA | HE-IBDV | BCA | SDS | Dulbecco's modified Eagle's medium | HERPES-SIMPLEX-VIRUS | heat-inactivated IBDV | mechanistic target of rapamycin (serine | BIOSYNTHESIS | PURIFICATION | lipopolysaccharide | SQSTM1 | phosphoinositide 3-kinase | RNA interference | PARTICLES | IBDV | SVP | LPS | complementary DNA | heat shock protein 90kDa alpha (cytosolic) | ANOVA | subunit 1 alpha | ATG5 | hpi | EIF2AK2 | viral protein | EIF2S1 | mAb | PAMP | eukaryotic translation initiation factor 2 | enhanced green fluorescent protein | glutathione S-transferase | coimmunoprecipitation | SYSTEM | subviral particle | autophagy-related 5 | small interfering RNA | double-stranded RNA | PRR | HSV-1 | CoIP | shRNA | short hairpin RNA | INFECTIOUS BURSAL DISEASE | herpes simplex virus 1 | cDNA | threonine kinase | EBSS | LC3 | Homo sapiens (human) | PBS | RNAi | golgi-associated PDZ and coiled-coil motif containing | TSC | MAP1LC3 | hours post-infection | pathogen-associated molecular patterns | GAPDH | Ni-NTA | INNATE IMMUNITY | BECN1 | tuberous sclerosis complex | Earle's balanced salt solution | IgG | TCID50 | microtubule-associated protein 1 light chain 3 | bicinchoninic acid | DMEM | multiplicity of infection | analysis of variance | Gallus gallus (chicken) | sodium dodecyl sulfate | glyceraldehyde-3-phosphate dehydrogenase | TLR | CELLS | eGFP | immunoglobulin G | MOI | eukaryotic translation initiation factor 2-alpha kinase 2 | GST | siRNA | MTOR | pattern recognition receptors | Beclin 1 | GOPC | monoclonal antibody | endoplasmic reticulum | Microscopy, Electron, Transmission | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Capsid Proteins - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Phagosomes - metabolism | Avibirnavirus - metabolism | Microscopy, Confocal | Animals | Lysosomes - metabolism | RNA Interference | Chickens | HEK293 Cells | HSP90 Heat-Shock Proteins - metabolism | Protein Binding | Cytosol - metabolism | Cell Membrane - metabolism | Proto-Oncogene Proteins c-akt - metabolism | RNA, Small Interfering - metabolism
Journal Article