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1. Full Text IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization
by Chu, Derek K., BHSc and Llop-Guevara, Alba, BHSc and Walker, Tina D., BSc and Flader, Kristin, BSc and Goncharova, Susanna, MD, PhD and Boudreau, Jeanette E., PhD and Moore, Cheryl Lynn, BSc and In, Tracy Seunghyun, BHSc and Waserman, Susan, MD, MSc and Coyle, Anthony J., PhD and Kolbeck, Roland, PhD and Humbles, Alison A., PhD and Jordana, Manel, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2012, Volume 131, Issue 1, pp. 187 - 200.e8
Allergy and Immunology | thymic stromal lymphopoietin | OX40 ligand | house dust mite | allergy | asthma | peanut | IL-25 | innate lymphoid cells | IL-33 | TH2 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Digestive allergic diseases | Biological and medical sciences | Allergic diseases | Medical sciences | Chronic obstructive pulmonary disease, asthma | Pneumology | OX40 Ligand - metabolism | Dendritic Cells - immunology | Humans | Hypersensitivity - immunology | Th2 Cells - immunology | Gastrointestinal Tract - immunology | Allergens - immunology | Hypersensitivity - metabolism | Interleukins - immunology | Female | Lung - metabolism | Receptors, Immunologic - immunology | Dendritic Cells - metabolism | Signal Transduction | Interleukin-33 | Interleukin-4 - metabolism | Stromal Cells - metabolism | Thymus Gland - cytology | Stromal Cells - immunology | STAT6 Transcription Factor - metabolism | Th2 Cells - metabolism | Interleukin-4 - immunology | Animals | OX40 Ligand - immunology | Arachis - immunology | Thymus Gland - immunology | Mice | Lung - immunology | Receptors, Immunologic - metabolism | Pyroglyphidae - immunology | Autoimmunity | Allergens | Allergic reaction | Studies | Food allergies | Antigens | Airway management | Disease | Rodents | Software | Allergies | Index Medicus | Abridged Index Medicus
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2. Full Text Distinct TLR-mediated pathways regulate house dust mite–induced allergic disease in the upper and lower airways
by Ryu, Ji-Hwan, PhD and Yoo, Jung-Yeon, BS and Kim, Min-Ji, BS and Hwang, Sang-Gyu, MS and Ahn, Kwang Chul, MS and Ryu, Jae-Chan, BS and Choi, Mi-Kyung, PhD and Joo, Jung Hee, PhD and Kim, Chang-Hoon, MD, PhD and Lee, Sang-Nam, PhD and Lee, Won-Jae, PhD and Kim, Jaesang, PhD and Shin, Dong Min, DDS, PhD and Kweon, Mi-Na, PhD and Bae, Yun Soo, PhD and Yoon, Joo-Heon, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2012, Volume 131, Issue 2, pp. 549 - 561
Allergy and Immunology | pathogen associated molecular pattern | allergic asthma | innate immunity | house dust mite | Allergic rhinitis | reactive oxygen species | epithelium | β-glucans | dual oxidase 2 | Toll-like receptor | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Otorhinolaryngology. Stomatology | Non tumoral diseases | Biological and medical sciences | Medical sciences | Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology | Asthma - metabolism | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Rhinitis, Allergic | NADPH Oxidases - metabolism | Hypersensitivity - immunology | NADPH Oxidases - immunology | Lipopolysaccharides - immunology | Rhinitis, Allergic, Perennial - metabolism | Hypersensitivity - metabolism | Reactive Oxygen Species - immunology | Respiratory Mucosa - immunology | Asthma - immunology | Lung - metabolism | Nasal Mucosa - metabolism | beta-Glucans - immunology | Respiratory System - immunology | Rhinitis, Allergic, Perennial - immunology | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Immunity, Innate - immunology | beta-Glucans - metabolism | Animals | Nasal Mucosa - immunology | Respiratory System - metabolism | Epithelial Cells - immunology | Toll-Like Receptor 2 - immunology | Mice | Respiratory Mucosa - metabolism | Dual Oxidases | Lung - immunology | Pyroglyphidae - immunology | Medical colleges | Asthma | Lipids | Gene expression | Allergies | Immune system | Index Medicus | Abridged Index Medicus
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3. Full Text Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation
by Juncadella, Ignacio J and Kadl, Alexandra and Sharma, Ashish K and Shim, Yun M and Hochreiter-Hufford, Amelia and Borish, Larry and Ravichandran, Kodi S
Nature (London), ISSN 0028-0836, 01/2013, Volume 493, Issue 7433, pp. 547 - 551
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Th2 Cells - secretion | Inflammation - pathology | Up-Regulation | Ovalbumin - immunology | Bronchoalveolar Lavage Fluid - immunology | rac1 GTP-Binding Protein - deficiency | Dust - immunology | Th2 Cells - immunology | Bronchi - immunology | Respiratory Hypersensitivity - pathology | Epithelial Cells - physiology | Allergens - immunology | Interleukins - immunology | Interleukins - biosynthesis | Bronchi - cytology | Bronchi - pathology | Lung - pathology | Interleukin-33 | Inflammation - immunology | Respiratory Hypersensitivity - immunology | Immunity, Innate - immunology | Animals | Epithelial Cells - immunology | Interleukin-10 - biosynthesis | Mice | Bronchoalveolar Lavage Fluid - chemistry | Interleukin-10 - immunology | Lung - immunology | Phagocytosis | rac1 GTP-Binding Protein - metabolism | Apoptosis | Pyroglyphidae - immunology | rac1 GTP-Binding Protein - genetics | Immune response | Epithelial cells | Bronchi | Physiological aspects | Inflammation | Research | Health aspects | Proteins | Cytokines | Rodents | Cells | Index Medicus
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4. Full Text Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma
by Klein Wolterink, Roel and Kleinjan, Alex and Nimwegen, Menno and Bergen, Ingrid and Bruijn, Marjolein and Levani, Yelvi and Heniks, Rudi
European journal of immunology, ISSN 0014-2980, 05/2012, Volume 42, Issue 5, pp. 1106 - 1116
Innate lymphoid cells | Innate immunity | House dust mite | Cytokines | Asthma | Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-1 Receptor-Like 1 Protein | Receptors, Interleukin - immunology | Interleukin-33 | Mice, Inbred C57BL | Cells, Cultured | Bronchoalveolar Lavage Fluid - immunology | Membrane Proteins - immunology | Th2 Cells - immunology | Interleukin-5 - biosynthesis | Lymph Nodes - immunology | Immunity, Innate | Interleukin-13 - biosynthesis | Animals | Lymphocytes - immunology | Antigens, Ly - immunology | Interleukins - administration & dosage | Asthma - immunology | Mice | Mice, Inbred BALB C | Receptors, Interleukin-7 - immunology | Lung - immunology | Interleukin-2 Receptor alpha Subunit - immunology | Pyroglyphidae - immunology | Lungs | Allergies | Index Medicus
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5. Full Text Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
by Castanhinha, Susana, MD and Sherburn, Rebekah, MSc and Walker, Simone, BSc and Gupta, Atul, MD(Res) and Bossley, Cara J., MD(Res) and Buckley, James, PhD and Ullmann, Nicola, MD and Grychtol, Ruth, MD and Campbell, Gaynor, PhD and Maglione, Marco, MD and Koo, Sergio, MPH and Fleming, Louise, MD and Gregory, Lisa, PhD and Snelgrove, Robert J., PhD and Bush, Andrew, MD and Lloyd, Clare M., PhD and Saglani, Sejal, MD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 312 - 322.e7
Allergy and Immunology | steroid resistance | Severe asthma | innate immunity | IL-33 | fungal sensitization | pediatric | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Interleukin-1 Receptor-Like 1 Protein | Anti-Asthmatic Agents - therapeutic use | Humans | Receptors, Interleukin - deficiency | Interleukin-13 - immunology | Omalizumab | Male | Th2 Cells - immunology | Interleukins - genetics | Interleukin-13 - genetics | Immunoglobulin E - immunology | Immunoglobulin E - genetics | Interleukins - immunology | Asthma - immunology | Female | Antibodies, Anti-Idiotypic - therapeutic use | Child | Th2 Cells - pathology | Disease Models, Animal | Animals, Newborn | Severity of Illness Index | Pyroglyphidae - chemistry | Antibodies, Monoclonal, Humanized - therapeutic use | Skin Tests | Receptors, Interleukin - immunology | Interleukin-33 | Asthma - drug therapy | Receptors, Interleukin - genetics | Alternaria - immunology | Cladosporium - immunology | Animals | Asthma - complications | Aspergillus fumigatus - immunology | Budesonide - therapeutic use | Mycoses - pathology | Adolescent | Mycoses - drug therapy | Mice | Mycoses - complications | Asthma - pathology | Mycoses - immunology | Pyroglyphidae - immunology | Pediatrics | Asthma in children | Fungi | Cytokines | Mortality | Smooth muscle | Inflammation | Allergies | Morbidity | Asthma | Milk | Index Medicus | Abridged Index Medicus | ABPA, Allergic bronchopulmonary aspergillosis | ICOS, Inducible costimulator | SPT, Skin prick test | sIgE, Specific IgE | BAL, Bronchoalveolar lavage | HDM, House dust mite | SAFS, Severe asthma with fungal sensitization | MMP-9, Matrix metalloproteinase 9 | Asthma and Lower Airway Disease | STRA, Severe therapy-resistant asthma | ILC, Innate lymphoid cell | AHR, Airway hyperresponsiveness
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6. Full Text Carrier‐bound nonallergenic Der p 2 peptides induce IgG antibodies blocking allergen‐induced basophil activation in allergic patients
by Chen, K.‐W and Focke‐Tejkl, M and Blatt, K and Kneidinger, M and Gieras, A and Dall'Antonia, F and Faé, I and Fischer, G and Keller, W and Valent, P and Valenta, R and Vrtala, S
Allergy (Copenhagen), ISSN 0105-4538, 05/2012, Volume 67, Issue 5, pp. 609 - 621
peptides | Der p 2 | house dust mite allergy | immunotherapy | Peptides | Immunotherapy | House dust mite allergy | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Medical sciences | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Dermatology | Leukocytes, Mononuclear - metabolism | Humans | Hypersensitivity - immunology | Molecular Sequence Data | Pyrophosphatases - antagonists & inhibitors | Antigens, Dermatophagoides - immunology | Vaccines, Conjugate - immunology | Lymphocyte Activation - immunology | Immunoglobulin E - immunology | Allergens - immunology | Antibody Specificity - immunology | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Leukocytes, Mononuclear - immunology | Basophils - immunology | Female | Cytokines - immunology | Amino Acid Sequence | Rabbits | Phosphoric Diester Hydrolases - metabolism | Cytokines - metabolism | Peptides - chemistry | Immunoglobulin E - metabolism | Peptides - immunology | Arthropod Proteins - immunology | Protein Binding - immunology | Pyrophosphatases - metabolism | Arthropod Proteins - chemistry | Animals | Antibodies, Blocking - immunology | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Hemocyanins - chemistry | Antigens, Dermatophagoides - chemistry | Basophils - metabolism | Pyroglyphidae - immunology | Arachnids | Immunoglobulins | Side effects | Vaccines | Allergies | Index Medicus | Allergens | Cytokines | Hypersensitivity | Immunoglobulin G | Vaccination | Immunoglobulin E | Lymphocytes T | Lymphocytes | Peripheral blood mononuclear cells | Leukocytes (basophilic)
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7. Full Text “Auto-anti-IgE”: Naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation
by Chan, Yih-Chih, PhD and Ramadani, Faruk, PhD and Santos, Alexandra F., MD and Pillai, Prathap, MD and Ohm-Laursen, Line, PhD and Harper, Clare E., MSc and Fang, Cailong, PhD and Dodev, Tihomir S., PhD and Wu, Shih-Ying, MSc and Ying, Sun, PhD and Corrigan, Christopher J., PhD and Gould, Hannah J., PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2014, Volume 134, Issue 6, pp. 1394 - 1401.e4
Allergy and Immunology | autoantibodies | IgE | basophil activation | Asthma | basophil inhibition | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Biological and medical sciences | Medical sciences | Chronic obstructive pulmonary disease, asthma | Pneumology | Cell Line | Immunoglobulin G - blood | Antibodies, Anti-Idiotypic - blood | Autoantibodies - blood | Humans | Antibodies, Anti-Idiotypic - immunology | Rats | Antigens, Plant - immunology | Phleum - immunology | Autoantibodies - immunology | Animals | Immunoglobulin E - immunology | Allergens - immunology | Calcium-Binding Proteins - immunology | Immunoglobulin G - immunology | Asthma - blood | Asthma - immunology | Basophils - immunology | Receptors, IgE - immunology | Autoimmunity | Allergens | Autoantibodies | Immunoglobulin G | Immunoglobulin E | Allergic reaction | Studies | Medical research | Hospitals | Biomedical research | Health services | Immunotherapy | Allergies | Immune system | Index Medicus | Abridged Index Medicus | MP, Milk powder | NAC, Non-atopic controls | FACS, Fluorescence-activated cell sorting | FITC, Fluorescein | AA, Atopic asthmatic subjects | MFI, Mean fluorescence intensity | PEFR, Peak expiratory flow rate | SPT, Skin prick test | ANA, Anti-nuclear autoantibodies | APC, Allophycocyanin | Tween 20 | HDM, House dust mite | PE, R-Phycoerythrin | BAT, Basophil activation test | NAA, Non-atopic asthmatic subjects | RT, Room temperature | HRP, Horseradish peroxidase | PBS-T, Phosphate-buffered saline | Mechanisms of Allergy and Clinical Immunology
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8. Full Text Biased generation and in situ activation of lung tissue-resident memory CD4 T cells in the pathogenesis of allergic asthma
by Turner, Damian L and Goldklang, Monica and Cvetkovski, Filip and Paik, Daniel and Trischler, Jordis and Barahona, Josselyn and Cao, Minwei and Dave, Ronak and Tanna, Nicole and D'Armiento, Jeanine M and Farber, Donna L
The Journal of immunology (1950), ISSN 0022-1767, 03/2018, Volume 200, Issue 5, pp. 1561 - 1569
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammation Mediators - immunology | Mice, Inbred C57BL | Hypersensitivity - immunology | Respiratory Hypersensitivity - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Animals | Allergens - immunology | Asthma - immunology | Pneumonia - immunology | Female | Mice | CD8-Positive T-Lymphocytes - immunology | Lung - immunology | Disease Models, Animal | Pyroglyphidae - immunology | Allergens | Immunological memory | Memory cells | Dendritic cells | Pathogenesis | CD8 antigen | House dust | Lymphocytes T | Exposure | Allergies | Asthma | CD4 antigen | Recruitment | Chronic exposure | Cell activation | Lungs | Lymphocytes | Respiratory tract diseases | Index Medicus | Abridged Index Medicus
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