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Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 02/2010, Volume 35, Issue 3, pp. 752 - 763
  The Wistar Kyoto (WKY) rat strain is a putative genetic model of comorbid depression and anxiety. Previous research showing increased kappa-opioid receptor... 
Depression | K-opioid receptor | Antidepressants | Piriform cortex | Wistar Kyoto rat | Dynorphin
Journal Article
Journal Article
Depression and Anxiety, ISSN 1091-4269, 10/2016, Volume 33, Issue 10, pp. 895 - 906
Kappa‐opioid receptor (KOR) antagonists are currently being considered for the treatment of a variety of neuropsychiatric conditions, including depressive,... 
anxiety | treatment | anxiety disorders | mood disorders | pharmacotherapy | substance use disorders | CREB PHOSPHORYLATION | PSYCHIATRY | RATS | COCAINE REWARD | ELEMENT-BINDING PROTEIN | RECEPTOR-AGONIST SALVINORIN | FORCED SWIM TEST | PSYCHOLOGY, CLINICAL | PSYCHOLOGY | INTRACRANIAL SELF-STIMULATION | ACUTE FLUOXETINE | BUPRENORPHINE | NUCLEUS-ACCUMBENS SHELL | Humans | Dynorphins - physiology | Dynorphins - therapeutic use | CREB-Binding Protein - genetics | Anti-Anxiety Agents - therapeutic use | Anxiety Disorders - drug therapy | Disease Models, Animal | Nucleus Accumbens - physiopathology | Receptors, Opioid, kappa - antagonists & inhibitors | Brain - physiopathology | Translational Medical Research | Gene Expression Regulation - physiology | Substance-Related Disorders - physiopathology | Substance-Related Disorders - complications | Antidepressive Agents - therapeutic use | Brain - drug effects | Gene Expression Regulation - drug effects | Receptors, Opioid, kappa - physiology | Animals | Narcotic Antagonists - therapeutic use | Reward | Nucleus Accumbens - drug effects | Anxiety Disorders - physiopathology | Stress, Psychological - complications | Stress, Psychological - physiopathology | Clinical trials | Substance abuse | Anxiety | Stress (Psychology) | Antidepressants | Protein binding | Narcotics | Rodents
Journal Article
Peptides, ISSN 0196-9781, 05/2017, Volume 91, pp. 40 - 48
We previously reported a series of novel endomorphin analogs with unnatural amino acid modifications. These analogs display good binding affinity and... 
Spinal antinociception | Antagonist | Endomorphin | Antibody | Dynorphin | CORD | MORPHINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | INVOLVEMENT | RELEASE | MU-OPIOID RECEPTOR | POTENT | PEPTIDOMIMETICS | ADMINISTERED ENDOMORPHIN-1 | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGY & PHARMACY | ANALGESIA | Analgesics, Opioid - antagonists & inhibitors | Naltrexone - analogs & derivatives | Opioid Peptides - pharmacology | Analgesics, Opioid - pharmacology | Male | Enkephalin, Leucine - administration & dosage | Opioid Peptides - administration & dosage | Receptors, sigma - antagonists & inhibitors | Dynorphins - chemistry | Enkephalin, Methionine - pharmacology | Pain - metabolism | Enkephalin, Leucine - antagonists & inhibitors | Naltrexone - pharmacology | Enkephalin, Methionine - chemistry | Pain - drug therapy | Enkephalin, Leucine - pharmacology | Analgesics, Opioid - chemistry | Antibodies - immunology | Enkephalin, Methionine - administration & dosage | Naltrexone - administration & dosage | Oligopeptides - chemistry | Enkephalin, Methionine - antagonists & inhibitors | Injections, Spinal | Oligopeptides - antagonists & inhibitors | Receptors, Opioid, kappa - antagonists & inhibitors | Receptors, Opioid, mu - antagonists & inhibitors | Dynorphins - antagonists & inhibitors | Enkephalin, Leucine - chemistry | Analgesia | Opioid Peptides - chemistry | Animals | Dynorphins - administration & dosage | Analysis of Variance | Analgesics, Opioid - administration & dosage | Naloxone - pharmacology | Opioid Peptides - antagonists & inhibitors | Narcotic Antagonists - pharmacology | Dynorphins - pharmacology | Mice | Oligopeptides - administration & dosage | Naloxone - administration & dosage | Oligopeptides - pharmacology | Pain Measurement | Fluorine - chemistry | Viral antibodies | Antibodies | Yuan (China) | Analysis
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2007, Volume 323, Issue 3, pp. 838 - 845
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 12/2012, Volume 37, Issue 13, pp. 2809 - 2816
Journal Article