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Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 05/2014, Volume 522, Issue 7, pp. 1506 - 1526
ABSTRACT Dynorphins, leumorphin, and neoendorphins are preprodynorphin (PPD)‐derived peptides and ligands for κ‐opioid receptors. Using an antibody to PPD... 
GABAergic neuron | double immunofluorescence labeling | opioid peptide | combined labeling of immunofluorescence and fluorescent mRNA signals | somatostatin | Double immunofluorescence labeling | Somatostatin | Combined labeling of immunofluorescence and fluorescent mRNA signals | Opioid peptide | IMMUNOHISTOCHEMICAL LOCALIZATION | ULTRASTRUCTURAL-LOCALIZATION | RECEPTOR MESSENGER-RNA | IN-SITU HYBRIDIZATION | KAPPA-OPIOID RECEPTOR | NEUROSCIENCES | CEREBRAL-CORTEX | ZOOLOGY | RAT CNS | VASOACTIVE INTESTINAL POLYPEPTIDE | CENTRAL-NERVOUS-SYSTEM | CHOLINE-ACETYLTRANSFERASE | Cell Count | Male | Neurons - cytology | RNA, Messenger - metabolism | Immunoenzyme Techniques | Neuropeptide Y - metabolism | Neocortex - metabolism | GABAergic Neurons - cytology | Somatosensory Cortex - cytology | Cell Adhesion Molecules, Neuronal - metabolism | Interneurons - cytology | Neurons - metabolism | GABAergic Neurons - metabolism | Dynorphins - metabolism | Somatostatin - metabolism | Extracellular Matrix Proteins - metabolism | Calbindin 2 - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Vesicular Glutamate Transport Proteins - metabolism | Protein Precursors - metabolism | Nerve Tissue Proteins - metabolism | Animals | Interneurons - metabolism | Fluorescent Antibody Technique | Glutamate Decarboxylase - metabolism | Neocortex - cytology | Mice | Nitric Oxide Synthase - metabolism | Serine Endopeptidases - metabolism | Somatosensory Cortex - metabolism | Neuropeptide Y | GABA | Glutamate | Neurons
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 06/2016, Volume 30, Issue 6, pp. 630 - 644
Journal Article
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 11/2010, Volume 285, Issue 47, pp. 36625 - 36634
Journal Article
Endocrinology, ISSN 0013-7227, 08/2013, Volume 154, Issue 8, pp. 2750 - 2760
Kisspeptin neurons located in the arcuate nucleus (ARN) coexpress dynorphin and neurokinin B (NKB) and may interact to influence gonadotropin secretion. Using... 
GNRH PULSE-GENERATOR | HORMONE SECRETION | MORPHOLOGIC EVIDENCE | FEMALE MOUSE | IN-VITRO | MESSENGER-RNA EXPRESSION | PHARMACOLOGICAL CHARACTERIZATION | ENDOCRINOLOGY & METABOLISM | MEDIAN-EMINENCE | KAPPA-OPIOID RECEPTOR | SUBSTANCE-P | Receptors, Neurokinin-2 - antagonists & inhibitors | Receptors, Tachykinin - metabolism | Analgesics, Non-Narcotic - pharmacology | Arcuate Nucleus of Hypothalamus - cytology | Male | Peptide Fragments - pharmacology | Substance P - pharmacology | Green Fluorescent Proteins - genetics | Neurokinin B - pharmacology | Quinolines - pharmacology | Kisspeptins - genetics | Piperidines - pharmacology | Neurons - physiology | Receptors, Neurokinin-3 - metabolism | Neurons - metabolism | Receptors, Neurokinin-2 - metabolism | Dynorphins - metabolism | Neurons - drug effects | Substance P - analogs & derivatives | Receptors, Neurokinin-3 - antagonists & inhibitors | Membrane Potentials - drug effects | Green Fluorescent Proteins - metabolism | Arcuate Nucleus of Hypothalamus - metabolism | Receptors, Opioid, kappa - agonists | Receptors, Neurokinin-3 - agonists | Receptors, Opioid, kappa - metabolism | Mice, Transgenic | Kisspeptins - metabolism | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Neurokinin B - metabolism | Patch-Clamp Techniques | Animals | Dynorphins - pharmacology | Kisspeptins - pharmacology | Mice | Oligopeptides - pharmacology
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 01/2011, Volume 300, Issue 1, pp. 202 - 210
Neurokinin B (NKB) and its cognate receptor neurokinin 3 (NK3R) play a critical role in reproduction. NKB and NK3R are coexpressed with dynorphin (Dyn) and... 
Estradiol | Hypothalamus | PHYSIOLOGY | GONADOTROPIN-SECRETION | ARCUATE NUCLEUS | MORPHOLOGIC EVIDENCE | MESSENGER-RNA | LUTEINIZING-HORMONE SECRETION | DYNORPHIN-A | ENDOCRINOLOGY & METABOLISM | MEDIAN-EMINENCE | GENE-EXPRESSION | NEURONS | HYPOGONADOTROPIC HYPOGONADISM | hypothalamus | estradiol | Rats, Wistar | Arcuate Nucleus of Hypothalamus - cytology | Peptide Fragments - pharmacology | Substance P - pharmacology | Neurokinin B - agonists | Neurokinin B - genetics | RNA, Messenger - metabolism | Kisspeptins | Arcuate Nucleus of Hypothalamus - drug effects | Receptors, Neurokinin-3 - metabolism | Female | Neurons - metabolism | Prosencephalon - metabolism | Neurons - drug effects | Substance P - analogs & derivatives | Receptors, Neurokinin-3 - genetics | Gonadotropin-Releasing Hormone - secretion | Estradiol - metabolism | Luteinizing Hormone - blood | Arcuate Nucleus of Hypothalamus - metabolism | Gene Expression Regulation | Proto-Oncogene Proteins c-fos - metabolism | Receptors, Neurokinin-3 - agonists | Rats | Organ Specificity | Neurokinin B - metabolism | Proteins - genetics | Feedback, Physiological | Animals | Proteins - metabolism | Signal Transduction - drug effects | Prosencephalon - cytology | Proto-Oncogene Proteins c-fos - genetics | Estrous Cycle - metabolism | Physiological aspects | Neurohormones | Genetic aspects | Research | Gonadotropin releasing hormone
Journal Article
Pain, ISSN 0304-3959, 07/2014, Volume 155, Issue 7, pp. 1293 - 1302
Lack of interleukin-17 leads to a modulated micro-environment and amelioration of mechanical hypersensitivity after peripheral nerve injury in mice.... 
Nerve injury | Animal model | Inflammation | Interleukin-17 | Neuropathic pain | CELLS | ASSAY | RAT | SPINAL-CORD | NEUROSCIENCES | BETA-ENDORPHIN | CLINICAL NEUROLOGY | IMMUNE | BEHAVIORAL HYPERSENSITIVITY | PAIN | HOST-DEFENSE | ANESTHESIOLOGY | INFLAMMATORY RESPONSE | Tumor Necrosis Factor-alpha - metabolism | Sciatic Nerve - injuries | Neuralgia - genetics | Peripheral Nerve Injuries - immunology | Enkephalins - metabolism | Interleukin-17 - immunology | Neuralgia - metabolism | Interleukin-13 - immunology | Behavior, Animal | beta-Endorphin - metabolism | Neuralgia - immunology | Interleukin-2 - immunology | Interleukin-1beta - metabolism | Peripheral Nerve Injuries - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Dynorphins - metabolism | Interleukin-6 - metabolism | Macrophages - immunology | Cytokines - immunology | Disease Models, Animal | Interleukin-2 - metabolism | Nociception | Central Nervous System Sensitization - immunology | Cytokines - metabolism | Hyperalgesia - metabolism | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-17 - genetics | Interleukin-1beta - immunology | Inflammation - immunology | Interleukin-13 - metabolism | Mice, Knockout | Hyperalgesia - immunology | Animals | Hyperalgesia - genetics | Interleukin-6 - immunology | Inflammation - genetics | T-Lymphocytes - immunology | Mice | Central Nervous System Sensitization - genetics | Peripheral Nerve Injuries - genetics | Interleukin-10 - immunology | Peroxidase - metabolism | Interleukins | Allergy | Allergic reaction
Journal Article
Endocrinology, ISSN 0013-7227, 06/2012, Volume 153, Issue 6, pp. 2800 - 2812
Journal Article
Endocrinology, ISSN 0013-7227, 04/2016, Volume 157, Issue 4, pp. 1555 - 1565
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2012, Volume 32, Issue 49, pp. 17582 - 17596
Activation of the dynorphin/kappa-opioid receptor (KOR) system by repeated stress exposure or agonist treatment produces place aversion, social avoidance, and... 
INTRAVENOUS COCAINE | ACTIVATED PROTEIN-KINASE | ELECTRODE VOLTAMMETRIC MEASUREMENTS | PLACE PREFERENCE | 5-HYDROXYINDOLEACETIC ACID | NUCLEUS-ACCUMBENS SHELL | TRANSPORTER KINETICS | MAJOR DEPRESSION | DORSAL RAPHE NUCLEUS | NEUROSCIENCES | KAPPA-OPIOID-RECEPTOR | Naltrexone - analogs & derivatives | Narcotic Antagonists - administration & dosage | Microinjections - methods | Nucleus Accumbens - metabolism | Dynorphins - physiology | Male | Synaptosomes - metabolism | Stress, Psychological - psychology | Corpus Striatum - metabolism | Raphe Nuclei - metabolism | Nicotine - adverse effects | Brain - metabolism | Naltrexone - pharmacology | Serotonin Plasma Membrane Transport Proteins - genetics | Substance Withdrawal Syndrome - metabolism | Stress, Psychological - metabolism | Membrane Transport Proteins - metabolism | Dynorphins - metabolism | Narcotic Antagonists - pharmacokinetics | Naltrexone - administration & dosage | Dopamine - metabolism | G-Protein-Coupled Receptor Kinase 3 - genetics | Receptors, Opioid, kappa - antagonists & inhibitors | p38 Mitogen-Activated Protein Kinases - physiology | G-Protein-Coupled Receptor Kinase 3 - physiology | Mice, Inbred C57BL | p38 Mitogen-Activated Protein Kinases - genetics | Mice, Transgenic | Avoidance Learning - physiology | Mice, Knockout | Receptors, Opioid, kappa - physiology | Serotonin Plasma Membrane Transport Proteins - metabolism | Cocaine - pharmacology | Animals | Raphe Nuclei - drug effects | Raphe Nuclei - physiology | Signal Transduction - drug effects | Serotonin - metabolism | Signal Transduction - physiology | Avoidance Learning - drug effects | Mice | Reward | Nucleus Accumbens - drug effects
Journal Article