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CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, ISSN 1386-0291, 2019, Volume 73, Issue 4, pp. 523 - 530
Although the inherited quantitative and qualitative disorders of fibrinogen are rare, in the course of time patients may develop complications including... 
BLOOD-CELL AGGREGATION | THROMBOSIS | PLASMA VISCOSITY | THROMBOEMBOLIC EVENTS | PERIPHERAL VASCULAR DISEASE | SIALIC-ACID | MECHANISMS | PATIENT | HEMATOLOGY | ACQUIRED DYSFIBRINOGENEMIA | FIBRINOGEN | FEATURES
Journal Article
BLOOD TRANSFUSION, ISSN 1723-2007, 05/2019, Volume 17, Issue 3, pp. 237 - 246
Background. Fibrinogen is produced in the liver and tends to be reduced in liver cirrhosis. Quantitative and qualitative tests exist to measure fibrinogen. We... 
linear regression model | DYSFIBRINOGENEMIA | fibrinogen | functional fibrinogen | HEMATOLOGY | cirrhosis | CLOT STRENGTH | Liver Diseases - blood | Thrombelastography | Models, Biological | Humans | Middle Aged | Fibrinogen - metabolism | Liver Diseases - pathology | Aged, 80 and over | Adult | Female | Male | Aged | Original
Journal Article
BLOOD TRANSFUSION, ISSN 1723-2007, 05/2019, Volume 17, Issue 3, pp. 247 - 254
Journal Article
Research and Practice in Thrombosis and Haemostasis, ISSN 2475-0379, 04/2019, Volume 3, Issue 2, pp. 173 - 183
Essentials The C‐terminal domain of the fibrinogen α chain (αC domain) is implicated in different severe diseases via clotting abnormalities or amyloid... 
fibrinogen αC domain | dysfibrinogenemia | Alzheimer’s disease | fibrinogen | renal amyloidosis | Proteins | Medical research | Researchers | Brain research | Peptides | Polymerization | Alzheimers disease | Binding sites
Journal Article
Blood Coagulation & Fibrinolysis, ISSN 0957-5235, 03/2019, Volume 30, Issue 2, pp. 80 - 84
Hypodysfibrinogenemia and protein C deficiency are coagulopathies and in this report, we describe a young patient with both defects confirmed by molecular... 
DYSFIBRINOGENEMIA | VARIANTS | DATABASE | hypodysfibrinogenemia | recurrent thrombophlebitis | protein C | deep venous thrombosis | HEMATOLOGY | ASSOCIATION | DEFICIENCY | Case studies | Gene mutations | Fibrinogen | Protein C | Thrombophlebitis | Genetic aspects | Health aspects
Journal Article
Journal of Clinical Pathology, ISSN 0021-9746, 02/2019, Volume 72, Issue 2, pp. 177 - 180
Most fibrinogen replacement strategies focus on quantitative deficiencies. A thrombin time (TT) mixing study helped to assess qualitative defects caused by... 
dysfibrinogenemia | fibrinogen | thrombin time | cryoprecipitate | PATHOLOGY | Studies | Antigens | Carbohydrates | Liver diseases | Laboratories | Patients | Thrombosis | Binding sites
Journal Article
The application of clinical genetics, ISSN 1178-704X, 2019, Volume 12, pp. 27 - 33
Dysfibrinogenemia is a rare inherited disease that results from mutation in one of the three fibrinogen genes. Diagnosis can be misleading since it may present... 
Medicine | Genotype & phenotype | Ultrasonic imaging | Polymerization | Mutation | Thromboembolism | Thrombosis | Age | Binding sites | Blood | Siblings | Veins & arteries | thrombophilia | dysfibrinogenemia | thrombosis
Journal Article
Thrombosis Research, ISSN 0049-3848, 02/2019, Volume 174, pp. 98 - 103
Clauss fibrinogen assay (CFA) is widely used as a screening test to detect fibrinogen disorders. However, CFA alone cannot distinguish quantitative and... 
Laboratory techniques | Fibrinogen disorders | Clot waveform analysis | Clauss fibrinogen assay | DYSFIBRINOGENEMIA | PLASMA | COAGULATION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Antigens | Medical research | Fibrin | Analysis | Fibrinogen | Medicine, Experimental | Medical screening
Journal Article
Chinese Journal of Medical Genetics, ISSN 1003-9406, 12/2018, Volume 35, Issue 6, pp. 812 - 814
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 11/2018, Volume 118, Issue 11, pp. 1867 - 1874
Abstract Background  Numerous mutations in FGA , FGB or FGG lead to congenital fibrinogen disorders (CFDs), but their epidemiology is not well characterized.... 
Coagulation and Fibrinolysis | afibrinogenemia | hypofibrinogenemia | mutation | dysfibrinogenemia | congenital | hypodysfibrinogenaemia | BLEEDING DISORDERS | STORAGE | DIAGNOSIS | MANAGEMENT | DEFICIENCIES | THROMBOPHILIA | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | hypodysfibrino-genaemia
Journal Article
Journal of Thrombosis and Thrombolysis, ISSN 0929-5305, 10/2018, Volume 46, Issue 3, pp. 409 - 419
We found a heterozygous dysfibrinogenemia caused by a substitution of AαArg16Cys. The proband suffered multiple cerebral infarctions. Routine coagulation tests... 
Medicine & Public Health | Hematology | Cardiology | Thrombosis | Fibrinogen | Dysfibrinogenemia | Scanning electron microscopy | Fibrin | Human serum albumin | Calcium | Lysis | Albumin | Polymerization | Mass spectroscopy | Immunoblotting | Thrombin | Fibers
Journal Article
by Luo, ML and Wei, AQ and Xiang, LQ and Yan, J and Liao, L and Deng, XL and Deng, DH and Cheng, P and Lin, FQ
JOURNAL OF THROMBOSIS AND THROMBOLYSIS, ISSN 0929-5305, 10/2018, Volume 46, Issue 3, pp. 409 - 419
We found a heterozygous dysfibrinogenemia caused by a substitution of A alpha Arg16Cys. The proband suffered multiple cerebral infarctions. Routine coagulation... 
MANAGEMENT | POLYMERIZATION | CLINICAL-FEATURES | Thrombosis | FIBRINOPEPTIDE | Dysfibrinogenemia | FIBRINOLYSIS | CONGENITAL DYSFIBRINOGENEMIA | Fibrinogen | THROMBOPHILIA | THROMBOTIC DISEASE | PERIPHERAL VASCULAR DISEASE | MUTATIONS | HEMATOLOGY | MOLECULAR-MECHANISMS
Journal Article
Research and Practice in Thrombosis and Haemostasis, ISSN 2475-0379, 10/2018, Volume 2, Issue 4, pp. 800 - 811
Essentials Fibrinogen Disorders are characterized by variable expressivity. Patients with fibrinogen disorders can present with bleeding, thrombosis, or both.... 
afibrinogenemia | fibrinogen disorders | fibrinogen mutations | dysfibrinogenemia | molecular modeling | Proteins | Antigens | Nuclear magnetic resonance--NMR | Congenital diseases | Laboratories | Tomography | Mutation | Thromboembolism | Thrombosis | Binding sites | Deoxyribonucleic acid--DNA | Crystal structure
Journal Article