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Journal of Biological Chemistry, ISSN 0021-9258, 07/2015, Volume 290, Issue 29, pp. 17784 - 17795
Journal Article
Molecular Therapy, ISSN 1525-0016, 02/2012, Volume 20, Issue 2, pp. 443 - 455
Journal Article
Neuroscience, ISSN 0306-4522, 2016, Volume 341, pp. 42 - 51
Journal Article
Transplantation, ISSN 0041-1337, 06/2008, Volume 85, Issue 12, pp. 1791 - 1801
Journal Article
Gene Therapy, ISSN 0969-7128, 09/2007, Volume 14, Issue 17, pp. 1249 - 1260
Using murine models, we have previously demonstrated that recombinant adeno-associated virus (rAAV)-mediated microdystrophin gene transfer is a promising... 
MEDICINE, RESEARCH & EXPERIMENTAL | LONG-TERM CORRECTION | gene transfer | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSDUCTION | T-CELL | MDX MICE | immune response | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | AAV | Duchenne muscular dystrophy | HEMOPHILIA-B | FACTOR-IX | IN-VIVO | GENETICS & HEREDITY | ADENOASSOCIATED VIRUS VECTORS | DUCHENNE MUSCULAR-DYSTROPHY | skeletal muscle | dog | DIRECTED GENE-THERAPY | Calmodulin - genetics | Dependovirus - genetics | Species Specificity | Parvoviridae Infections - immunology | Molecular Sequence Data | RNA, Messenger - analysis | Genetic Vectors - adverse effects | Muscle Fibers, Skeletal - virology | Muscle, Skeletal - immunology | Base Sequence | Muscular Dystrophy, Duchenne - immunology | Models, Animal | Muscular Dystrophy, Animal - therapy | Muscular Dystrophy, Duchenne - therapy | Transgenes | Dystrophin - metabolism | Transduction, Genetic - methods | Immunosuppressive Agents - administration & dosage | T-Lymphocytes, Cytotoxic - immunology | Muscular Dystrophy, Animal - immunology | Lymphocyte Activation | Mice, Inbred C57BL | Injections, Intramuscular | Muscle Fibers, Skeletal - immunology | Reverse Transcriptase Polymerase Chain Reaction | Genetic Vectors - genetics | Animals | Genetic Engineering | Dystrophin - genetics | Interferon-gamma - immunology | Cyclosporine - administration & dosage | Dogs | Mice | beta-Galactosidase - genetics | Genetic Therapy - adverse effects | Genetic Therapy - methods | Immune response | Genetic transformation | Physiological aspects | Muscles | Genetic aspects | Dependoviruses | Research | Health aspects | Signal transduction | Gene therapy | Adenoviruses | Muscular dystrophy | Immune system | Index Medicus
Journal Article
Journal Article
Journal Article
Neuroscience, ISSN 0306-4522, 2006, Volume 142, Issue 4, pp. 1055 - 1069
Perineuronal nets (PNs) are lattice-like condensations of the extracellular matrix (ECM) that envelop synapses and decorate the surface of subsets of neurons... 
aggrecan | phosphacan | RPTPβ | perineuronal net | CSPGs | extracellular matrix | RAT CEREBRAL-CORTEX | DYSTROPHIN-GLYCOPROTEIN COMPLEX | BRAIN EXTRACELLULAR-MATRIX | CONGENITAL MUSCULAR-DYSTROPHIES | NEUROSCIENCES | ACETYLCHOLINE-RECEPTOR | VISUAL-CORTEX | CENTRAL-NERVOUS-SYSTEM | PERINEURONAL NETS | CHONDROITIN SULFATE PROTEOGLYCAN | NEUROMUSCULAR-JUNCTION | RPTP beta | Central Nervous System - ultrastructure | Aggrecans - chemistry | Chondroitin Sulfate Proteoglycans - chemistry | Extracellular Matrix - metabolism | Receptor-Like Protein Tyrosine Phosphatases, Class 5 | Central Nervous System - embryology | Protein Tyrosine Phosphatases - immunology | Central Nervous System - growth & development | Epitopes - immunology | Protein Tyrosine Phosphatases - chemistry | Protein Tyrosine Phosphatases - genetics | Synapses - metabolism | Antibody Specificity - immunology | Cell Differentiation - physiology | Antibodies, Monoclonal - immunology | CD57 Antigens - immunology | Aggrecans - immunology | Cells, Cultured | Chondroitin Sulfate Proteoglycans - metabolism | Rats | Synapses - ultrastructure | Aggrecans - metabolism | Chondroitin Sulfate Proteoglycans - immunology | Rats, Sprague-Dawley | Mice, Knockout | Immunohistochemistry - methods | Animals | Growth Cones - metabolism | Growth Cones - ultrastructure | Amino Acid Motifs - immunology | CD57 Antigens - chemistry | Epitopes - chemistry | Mice | Tyrosine | Cats | Neurosciences | Proteoglycans | Phosphatases | Neurons | Nurses | Monoclonal antibodies | Phenols | Sulfates | Antigenic determinants | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2018, Volume 115, Issue 39, pp. E9182 - E9191
In gene therapy for Duchenne muscular dystrophy there are two potential immunological obstacles. An individual with Duchenne muscular dystrophy has a genetic... 
Gene replacement therapy | Mdx/mTRG2 mice | DNA plasmid | Duchenne muscular dystrophy | Microdystrophin | STEM-CELLS | microdystrophin | TRANSGENIC MDX MICE | MULTIDISCIPLINARY SCIENCES | MUSCULAR-DYSTROPHY | PYRUVATE-KINASE PK | mdx/mTRG2 mice | SOMATIC REVERSION SUPPRESSION | gene replacement therapy | ADENOASSOCIATED VIRAL VECTORS | MYELIN BASIC-PROTEIN | SKELETAL-MUSCLE | MOUSE MODEL | IN-VIVO | DNA - pharmacokinetics | Dependovirus - genetics | Muscle Strength - genetics | Male | Muscle Strength - immunology | DNA - genetics | Plasmids - pharmacology | Animals | Dystrophin - genetics | Genetic Vectors - pharmacology | Muscular Dystrophy, Duchenne - immunology | Mice, Inbred mdx | Plasmids - genetics | Dystrophin - immunology | Mice | Muscular Dystrophy, Duchenne - metabolism | Muscular Dystrophy, Duchenne - genetics | Muscular Dystrophy, Duchenne - therapy | Dystrophin - metabolism | Disease Models, Animal | Genetic Therapy - methods | Care and treatment | Plasmids | Genetic aspects | Gene therapy | Health aspects | Methods | Multiple sclerosis | Antibodies | Viruses | Diabetes mellitus (insulin dependent) | Immunity | Muscular dystrophy | Proteins | Immunology | Technology | Duchenne's muscular dystrophy | Plasmid DNA | Dystrophin | Deoxyribonucleic acid--DNA | Recombinant | Myelin | Diabetes mellitus | Muscles | Gene expression | Insulin | Immunogenicity | Muscle function | Mutation | Dystrophy | Index Medicus | mdx | Biological Sciences | PNAS Plus | mTRG2 mice
Journal Article