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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 01/2018, Volume 141, Issue 1, pp. 152 - 162
Background: Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are both forms of eczema and are common inflammatory skin diseases with a central role... 
Allergic contact dermatitis | atopic dermatitis | IMMUNOLOGY | IL-22 | SKIN BARRIER | prostaglandin E-2 | ATOPIC-DERMATITIS | ALLERGY | T(H)22 cells | IMMUNE-RESPONSES | INFLAMMATION | GENE-EXPRESSION | BETAMETHASONE | CELL-DIFFERENTIATION | MURINE MODELS | CD4(+) T cells | T(H)17 cells | T-CELLS | TH17 CELLS
Journal Article
Journal Article
International Immunopharmacology, ISSN 1567-5769, 09/2011, Volume 11, Issue 9, pp. 1166 - 1172
(AS), an herb used in traditional Chinese medicine, is thought to have anti-inflammatory activities. Ligustilide is its most abundant ingredient. This study... 
Mitogen-activated protein kinase | Activator protein-1 | Ligustilide | Nitric oxide | Nuclear factor κB | ACTIVATION | NITRIC-OXIDE SYNTHASE | DYSMENORRHEA | IMMUNOLOGY | ENDOMETRIOSIS | Nuclear factor kappa B | ISOBENZOFURANONE | PATHOGENESIS | ANTIOXIDANT | PHARMACOLOGY & PHARMACY | TNF-ALPHA | ANGELICA-SINENSIS | PROSTAGLANDIN E-2 | Nitric Oxide Synthase Type II - biosynthesis | Reactive Oxygen Species - metabolism | Transcription Factor RelA - antagonists & inhibitors | Dinoprostone - biosynthesis | Transcription Factor AP-1 - genetics | Transcription Factor AP-1 - metabolism | Transcription Factor RelA - genetics | Mitogen-Activated Protein Kinase Kinases - metabolism | I-kappa B Kinase - metabolism | I-kappa B Kinase - antagonists & inhibitors | Nitric Oxide Synthase Type II - antagonists & inhibitors | MAP Kinase Kinase 4 - antagonists & inhibitors | Phosphorylation - drug effects | Cell Line | Nitric Oxide - biosynthesis | Nitric Oxide - antagonists & inhibitors | 4-Butyrolactone - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | I-kappa B Kinase - genetics | Down-Regulation - drug effects | Macrophages - enzymology | Macrophages - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Transcription Factor AP-1 - antagonists & inhibitors | Animals | MAP Kinase Signaling System - drug effects | Nitric Oxide Synthase Type II - genetics | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | 4-Butyrolactone - analogs & derivatives | Dinoprostone - antagonists & inhibitors | Tumor Necrosis Factor-alpha - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
by Wang, HL and Du, L and Liu, F and Wei, ZY and Gao, L and Feng, WH
JOURNAL OF VIROLOGY, ISSN 0022-538X, 11/2019, Volume 93, Issue 21
Porcine reproductive and respiratory syndrome virus (PRRSV) is widely prevalent in pigs, resulting in significant economic losses worldwide. A compelling... 
PROSTAGLANDIN E-2 PRODUCTION | PHOSPHATIDYLINOSITOL 3-KINASE | PROTEIN-KINASE | P38 MAPK | NECROSIS-FACTOR-ALPHA | T-CELL | nsp11 | TAX PROTEIN | REPLICATION | VIROLOGY | inflammation | IL-17 | IL-17 EXPRESSION | INFECTION | PRRSV
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 2015, Volume 172, Issue 1, pp. 24 - 37
Background and Purpose N-docosahexaenoylethanolamine (DHEA) is the ethanolamine conjugate of the long-chain polyunsaturated n-3 fatty acid docosahexaenoic... 
PLASMA | CONCISE GUIDE | NITRIC-OXIDE SYNTHASE | INFLAMMATION | OXYGENATION | ANANDAMIDE | PHARMACOLOGY & PHARMACY | FATTY-ACIDS | FISH-OIL | KAPPA-B | ETHANOLAMIDE | Endocannabinoids - metabolism | Bornanes - pharmacology | Male | NF-kappa B - metabolism | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | PPAR gamma - metabolism | Piperidines - pharmacology | Thiazolidinediones - pharmacology | Pyrazoles - pharmacology | Cell Line | Indenes - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Dehydroepiandrosterone - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Arachidonic Acids - pharmacology | Mice, Knockout | Dinoprostone - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Macrophages - metabolism | Animals | PPAR gamma - antagonists & inhibitors | Interferon-beta - metabolism | Anilides - pharmacology | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Nitric Oxide - metabolism | Myeloid Differentiation Factor 88 - metabolism | Androgens | Dehydroepiandrosterone | DNA microarrays | Anti-inflammatory drugs | RNA | Ethanolamines | Macrophages | Gene expression | Fatty acids | Medical research | Rodents | Research Papers | arrive guidelines | pharmacology | fatty-acids | cannabinoid receptor | prostaglandin e-2 | nitric-oxide synthase | anandamide | fish-oil | concise guide | kappa-b
Journal Article
Journal Article
Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 08/2018, Volume 156, pp. 295 - 301
As a part of a broader structure-activity relationship study of substituted 2-aminopyrimidines, the influence of the C-5 substitution on inhibition of... 
CHEMISTRY, MEDICINAL | ANALGESIC ACTIVITIES | ANTICANCER AGENTS | Prostaglandin E-2 | CYCLOOXYGENASES | Pyrimidines | POTENT | NITRIC-OXIDE PRODUCTION | THERAPY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOLOGICAL EVALUATION | Inhibitor | DUAL INHIBITORS | DERIVATIVES | Suzuki-Miyaura reaction
Journal Article
EUROPEAN JOURNAL OF PHARMACOLOGY, ISSN 0014-2999, 04/2018, Volume 824, pp. 17 - 23
In this study, a series of rosmarinic acid and analogs were investigated for their anti-inflammatory potential against LPS-induced alveolar macrophages (MH-S).... 
LUNG | ACID | Prostaglandin E-2 | AIRWAY INFLAMMATION | Alveolar macrophages | Ethyl rosmarinate | OBSTRUCTIVE PULMONARY-DISEASE | INFLAMMATORY MECHANISMS | PATHWAY | Nitric oxide | ANIMAL-MODELS | ASTHMA | PHARMACOLOGY & PHARMACY | Chronic obstructive pulmonary disease | NF-KAPPA-B | COPD PATIENTS
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2011, Volume 128, Issue 1, pp. 66 - 72.e1
Researchers have debated whether regulation of the COX enzymes (COX-1 and COX-2), which mediate production of prostaglandins (PGs), affects the pathogenesis of... 
α-smooth muscle actin | fibroblast | chronic rhinosinusitis | cyclooxygenase | nasal mucosa | Aspirin intolerance | asthma | prostaglandin E 2 | nasal polyp | alpha-smooth muscle actin | LUNG | EICOSANOIDS | CYCLOOXYGENASE-2 | IMMUNOLOGY | FIBROBLASTS | prostaglandin E-2 | OBSTRUCTIVE PULMONARY-DISEASE | EPITHELIAL-CELLS | MESSENGER-RNA | ALLERGY | CYSTIC-FIBROSIS | SENSITIVE ASTHMATICS
Journal Article