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Journal of Clinical Investigation, ISSN 0021-9738, 09/2011, Volume 121, Issue 9, pp. 3564 - 3577
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2008, Volume 118, Issue 1, pp. 183 - 194
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2009, Volume 206, Issue 1, pp. 233 - 248
Atherosclerosis involves a macrophage-rich inflammation in the aortic intima. It is increasingly recognized that this intimal inflammation is paralleled over... 
B-CELLS | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | ORGAN DEVELOPMENT | IMMUNE-RESPONSES | FOLLICULAR DENDRITIC CELLS | REGULATORY T-CELLS | SMOOTH-MUSCLE-CELLS | IMMUNOLOGY | E-DEFICIENT MICE | AUTOIMMUNE-DISEASE | LASER MICRODISSECTION | Leukocytes, Mononuclear - metabolism | Aorta, Abdominal - growth & development | Atherosclerosis - genetics | Gene Expression Profiling | Lymphoid Tissue - growth & development | Chemokine CCL21 - metabolism | Lymphotoxin beta Receptor - physiology | Tunica Media - growth & development | In Situ Hybridization | Biological Transport | Tunica Media - metabolism | Aging | Aorta, Abdominal - metabolism | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Chemokine CXCL13 - genetics | Mice, Inbred C57BL | Cells, Cultured | Tunica Intima - growth & development | Lymphoid Tissue - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Chemokine CCL21 - genetics | Connective Tissue - metabolism | Mice, Knockout | Organogenesis | Tunica Intima - metabolism | Lymphoid Tissue - cytology | Animals | Connective Tissue - growth & development | Apolipoproteins E - genetics | Chemokine CXCL13 - metabolism | Leukocytes, Mononuclear - cytology | Signal Transduction - physiology | Lymphotoxin beta Receptor - antagonists & inhibitors | Mice | Cluster Analysis
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2017, Volume 58, Issue 8, pp. 1536 - 1547
HDL plays crucial roles at multiple stages of the pathogenesis of atherosclerosis. AMP-activated protein kinase (AMPK) is a therapeutic candidate for the... 
Apolipoprotein E deficient | Adenosine monophosphate-activated protein kinase | Atherosclerosis | Reverse cholesterol transport | atherosclerosis | reverse cholesterol transport | SR-BI | PROTEIN-KINASE | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | apolipoprotein E deficient | IDENTIFICATION | REDUCES ATHEROSCLEROSIS | HDL | EFFLUX | PARAOXONASE-1 | adenosine monophosphate-activated protein kinase | EXPRESSION | Cell Line | AMP-Activated Protein Kinases - metabolism | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Mice, Inbred C57BL | Lipoproteins, HDL - metabolism | Body Weight - drug effects | Male | Hepatocytes - metabolism | Enzyme Activation - drug effects | Atherosclerosis - metabolism | Gene Expression Regulation - drug effects | Atherosclerosis - enzymology | Animals | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | CD36 Antigens - metabolism | Lipid Peroxidation - drug effects | Mice | Macrophages, Peritoneal - metabolism | Hepatocytes - drug effects | ATP Binding Cassette Transporter 1 - genetics | Phosphates | AMP | Liver | Paraoxonase 1 | Lipid peroxidation | Inflammation | Glucose | Paraoxonase | AMP-activated protein kinase | Kinases | Macrophages | Cholesterol | High fat diet | ABCA1 protein | Antioxidants | Lipoproteins | Cell activation | Apolipoprotein E | Arteriosclerosis | ATP-binding protein | Peroxidase | Metformin | Lipoproteins (high density)
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 07/2011, Volume 25, Issue 7, pp. 2447 - 2455
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2006, Volume 26, Issue 9, pp. 2117 - 2124
OBJECTIVE—Osteoprotegerin (OPG), a member of the tumor necrosis factor (TNF) superfamily of proteins, plays an important role in bone remodeling and is... 
Vascular calcification | Apolipoprotein E-deficient mice | Atherosclerosis | Osteoprotegerin | apolipoprotein E-deficient mice | atherosclerosis | MYOCARDIAL-INFARCTION | MATRIX GLA PROTEIN | BONE METABOLISM | vascular calcification | HEART-FAILURE | DEFICIENT MICE | CORONARY CALCIFICATION | ARTERIAL CALCIFICATION | RANK LIGAND | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | osteoprotegerin | Mice, Knockout - genetics | Receptor Activator of Nuclear Factor-kappa B | Membrane Glycoproteins - metabolism | Calcium - metabolism | Glycoproteins - metabolism | Male | RANK Ligand | Aorta - metabolism | Brachiocephalic Trunk - pathology | Matrix Metalloproteinase 9 - metabolism | Brachiocephalic Trunk - metabolism | Receptors, Tumor Necrosis Factor - blood | Aging | Female | Aorta - physiopathology | Calcinosis - metabolism | Myocytes, Smooth Muscle - metabolism | Receptors, Tumor Necrosis Factor - genetics | Glycoproteins - genetics | Receptors, Tumor Necrosis Factor - metabolism | Atherosclerosis - pathology | Cell Survival | Mice, Inbred C57BL | Glycoproteins - blood | Receptors, Cytoplasmic and Nuclear - genetics | Atherosclerosis - metabolism | Disease Progression | Aorta - pathology | Receptors, Cytoplasmic and Nuclear - blood | Animals | Carrier Proteins - metabolism | Calcinosis - prevention & control | Mice | Calcinosis - pathology | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 10/2012, Volume 111, Issue 10, pp. 1274 - 1285
RATIONALE:Atherosclerosis is a chronic inflammatory disease of the arterial wall. Several proinflammatory cytokines are known to promote atherosclerosis, but... 
atherosclerosis | vascular inflammation | cytokines | chemokines | inflammation | leukocyte recruitment | CARDIAC & CARDIOVASCULAR SYSTEMS | IL-27 | NECROSIS-FACTOR-ALPHA | T-HELPER-CELLS | IMMUNE | REDUCES ATHEROSCLEROSIS | WSX-1 | MONOCYTE | PERIPHERAL VASCULAR DISEASE | INFECTION | CHRONIC INFLAMMATION | HEMATOLOGY | E-DEFICIENT MICE | Myeloid Cells - cytology | Tumor Necrosis Factor-alpha - metabolism | Male | Aorta - metabolism | Th1 Cells - immunology | Interleukins - metabolism | CD11c Antigen - metabolism | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Signal Transduction - immunology | Th17 Cells - metabolism | Mice, Mutant Strains | Myeloid Cells - immunology | Female | Th17 Cells - cytology | Chemokine CCL2 - metabolism | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - metabolism | Receptors, Cytokine - metabolism | Receptors, LDL - genetics | Atherosclerosis - immunology | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Receptors, LDL - metabolism | Aorta - immunology | Atherosclerosis - metabolism | Interleukin-17 - metabolism | Animals | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology | Myeloid Cells - metabolism | Th17 Cells - immunology | Mice | Th1 Cells - cytology | Aorta - cytology | CD11b Antigen - metabolism
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 06/2009, Volume 50, Issue 6, pp. 1090 - 1100
The role of farnesoid X receptor (FXR) in the development of atherosclerosis has been unclear. Here, LDL receptor (LDLR-/-) or apolipoprotein E (apoE(-/-))... 
Cholesterol 7α-hydroxylase | Sterol 12 α-hydroxylase | Atherosclerosis | Small heterodimer partner | atherosclerosis | TRIGLYCERIDE LEVELS | TRANSGENIC EXPRESSION | NEGATIVE FEEDBACK-REGULATION | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BILE-ACID SYNTHESIS | ESTROGEN-RECEPTOR | DENSITY-LIPOPROTEIN CHOLESTEROL | cholesterol 7 alpha-hydroxylase | NONFASTING TRIGLYCERIDES | small heterodimer partner | E-DEFICIENT MICE | sterol 12 alpha-hydroxylase | Dyslipidemias - genetics | Apolipoproteins E - deficiency | Gene Expression - drug effects | Steroid 12-alpha-Hydroxylase - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - deficiency | Atherosclerosis - genetics | Male | Lipids - blood | Receptors, LDL - deficiency | Dyslipidemias - prevention & control | Female | Indoles - pharmacology | Receptors, LDL - genetics | Atherosclerosis - pathology | Mice, Inbred C57BL | Bile Acids and Salts - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Atherosclerosis - metabolism | Mice, Knockout | Azepines - pharmacology | Cholesterol 7-alpha-Hydroxylase - genetics | Steroid 12-alpha-Hydroxylase - genetics | Animals | Apolipoproteins E - genetics | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Dyslipidemias - metabolism | Mice | Cholesterol 7-alpha-Hydroxylase - antagonists & inhibitors | Atherosclerosis - prevention & control | Receptors, Cytoplasmic and Nuclear - metabolism | sterol 12 α-hydroxylase | cholesterol 7α-hydroxylase
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2015, Volume 465, Issue 4, pp. 732 - 738
Journal Article