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e3-ligase (35) 35
life sciences & biomedicine (31) 31
science & technology (31) 31
animals (19) 19
cell biology (18) 18
humans (16) 16
ubiquitin (14) 14
ubiquitin-protein ligases - metabolism (12) 12
ubiquitination (11) 11
ligases (9) 9
proteins (9) 9
biology (8) 8
mice (8) 8
ubiquitin-protein ligases - genetics (8) 8
biochemistry & molecular biology (6) 6
oncology (6) 6
protein degradation (6) 6
signal transduction (6) 6
analysis (5) 5
cancer (5) 5
models, biological (5) 5
proteasome endopeptidase complex - metabolism (5) 5
protein binding (5) 5
proteolysis (5) 5
apoptosis (4) 4
cells, cultured (4) 4
membrane proteins - metabolism (4) 4
neurosciences (4) 4
neurosciences & neurology (4) 4
physiological aspects (4) 4
proteasome (4) 4
protein structure, tertiary (4) 4
review (4) 4
sumo (4) 4
ubiquitin - metabolism (4) 4
amino acid sequence (3) 3
binding (3) 3
bioscience (3) 3
calcium (3) 3
carrier proteins - metabolism (3) 3
cell (3) 3
cell nucleus - metabolism (3) 3
cycle (3) 3
drosophila proteins - metabolism (3) 3
female (3) 3
gene expression (3) 3
hela cells (3) 3
landes (3) 3
lif (3) 3
male (3) 3
mass spectrometry (3) 3
molecular sequence data (3) 3
organogenesis (3) 3
rats (3) 3
tumor suppressor (3) 3
tumor suppressor protein p53 - metabolism (3) 3
active transport, cell nucleus (2) 2
adult stem cells (2) 2
axotrophin/march-7 (2) 2
blotting, western (2) 2
botulinum neurotoxin light chain (2) 2
ddc:610 (2) 2
degradation (2) 2
dna damage (2) 2
e3‐ligase (2) 2
enzyme activation (2) 2
enzymes (2) 2
gene expression regulation - genetics (2) 2
gene expression regulation, plant (2) 2
genetic aspects (2) 2
genetics & heredity (2) 2
half-life (2) 2
his-sumo1 (2) 2
leupeptins - pharmacology (2) 2
life sciences & biomedicine - other topics (2) 2
march-7 (2) 2
membrane proteins - genetics (2) 2
messenger rna (2) 2
mice, knockout (2) 2
mitochondria (2) 2
muscle, skeletal - drug effects (2) 2
neoplasms (2) 2
neoplasms. tumors. oncology. including cancer and carcinogens (2) 2
nerve tissue proteins - metabolism (2) 2
neurodegenerative diseases (2) 2
ni2 + pull down (2) 2
nuclear proteins - physiology (2) 2
persistence (2) 2
phosphorylation (2) 2
plant proteins - metabolism (2) 2
plant sciences (2) 2
polyubiquitination (2) 2
protein conformation (2) 2
protein processing, post-translational (2) 2
proteinabbau (2) 2
proto-oncogene proteins - metabolism (2) 2
proto-oncogene proteins c-mdm2 - metabolism (2) 2
ranbp2 ir1 + m (2) 2
recombinant fusion proteins - metabolism (2) 2
research paper (2) 2
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Trends in cell biology, ISSN 0962-8924, 06/2014, Volume 24, Issue 6, pp. 352 - 359
Highlights • E2s and E3s work together to catalyze the transfer of ubiquitin to substrate. • The rate of ubiquitin transfer to the substrate governs its... 
Pathology | ubiquitin proteasome system | E3-ligase | E2-conjugating | proteolysis | E1-activating | Proteolysis | Ubiquitin proteasome system | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Proteasome Endopeptidase Complex - metabolism | Humans | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Ubiquitin | Index Medicus
Journal Article
Cells (Basel, Switzerland), ISSN 2073-4409, 07/2018, Volume 7, Issue 8, p. 87
Lafora disease (LD, OMIM254780) is a rare and fatal form of progressive myoclonus epilepsy (PME). Among PMEs, LD is unique because of the rapid neurological... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Ubiquitin | Oxidative stress | Carbohydrates | Disease | Myoclonus | Glycogen | Epilepsy | Genes | Genomes | Phosphatase | Metabolism | Kinases | Proteins | Convulsions & seizures | Ubiquitination | Databases | Protein folding | Diabetes | Mutation | Endoplasmic reticulum | Ubiquitin-protein ligase | Dementia | malin | E3-ligase | proteostasis | glycogen accumulation | ubiquitination | Lafora disease
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 33, pp. 34342 - 34357
Journal Article
Current biology, ISSN 0960-9822, 02/2020, Volume 30, Issue 3, pp. 465 - 479.e5
In yeast, the main ubiquitin ligase responsible for the sorting of proteins to the lysosomal vacuole is Rsp5, a member of the Nedd4 family of ligases whose... 
E3-ligase | endosome | lysosome | ubiquitin | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
Journal Article
Frontiers in bioscience, ISSN 1093-9946, 06/2012, Volume 17, Issue 6, pp. 2197 - 2212
The Ubiquitin Proteasome System (UPS) is a major regulator of protein abundance in the cell. The UPS influences the functions of multiple biological processes... 
E3-ligase | Phosphorylation | Ubiquitination | Oncogene | SCF | Review | Beta-TRCP | Fbw7 | Tumor suppressor | Cancer | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology
Journal Article
Journal of experimental botany, ISSN 1460-2431, 10/2019, Volume 70, Issue 20, pp. 5643 - 5657
A comprehensive tissue type-specific transcriptional study identifies 45 genes consistently differentially expressed during Boechera sexual as compared with... 
Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Index Medicus | E3-ligase | Research Papers | F-box | RNA-seq | Apomixis | Boechera | laser-assisted microdissection | tissue-specific transcriptome | nucellus tissue | megasporogenesis | plant reproduction
Journal Article