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Annals of Pharmacotherapy, ISSN 1060-0280, 06/2012, Volume 46, Issue 6, pp. 802 - 811
Journal Article
BRITISH JOURNAL OF CANCER, ISSN 0007-0920, 05/2019, Volume 120, Issue 11, pp. 1026 - 1032
BACKGROUND: This subgroup analysis of a phase 3 study compares outcomes for eribulin versus dacarbazine in patients with leiomyosarcoma. METHODS: Patients >=... 
MESYLATE | SITE | PROGNOSTIC-FACTORS | E7389 | ONCOLOGY | MESILATE | SURVEILLANCE | SOFT-TISSUE SARCOMA | EPIDEMIOLOGY | GEMCITABINE | Dacarbazine | Uterus | Safety management | Subgroups | Liposarcoma | Sarcoma
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9769, pp. 914 - 923
Journal Article
Oncology, ISSN 0030-2414, 07/2018, Volume 94, Issue Suppl 1, pp. 16 - 18
Eribulin, a non-taxane inhibitor of microtubule dynamics, is approved for the treatment of metastatic breast cancer patients after progression with... 
Clinical Study | Metastatic breast cancer | Chemotherapy | Eribulin | Dialysis | Taxanes | HALICHONDRIN-B | E7389 | ONCOLOGY | Index Medicus
Journal Article
Annals of Oncology, ISSN 0923-7534, 2017, Volume 28, Issue 9, pp. 2241 - 2247
Background: Eribulin is a microtubule dynamics inhibitor with a novel mechanism of action. This phase 3 study aimed to compare overall survival (OS) in... 
Phase 3 | Chemotherapy | Eribulin | Non-small cell lung cancer | non-small cell lung cancer | phase 3 | TRIAL | ONCOLOGY | MESYLATE E7389 | eribulin | TAXANE | chemotherapy | DOCETAXEL | ERLOTINIB | Index Medicus
Journal Article
Oncology, ISSN 0030-2414, 07/2018, Volume 94, Issue Suppl 1, pp. 19 - 28
Objectives: Predictive factors of response to eribulin are lacking. We aimed to investigate the activity and safety of eribulin in a real-world population of... 
Clinical Study | Metastatic breast cancer | Eribulin | Progression-free survival | Discriminant functional analysis | MESYLATE | E7389 | ANALOG | ONCOLOGY | TUMORS | Index Medicus
Journal Article
NATURE REVIEWS DRUG DISCOVERY, ISSN 1474-1776, 03/2011, Volume 10, Issue 3, pp. 173 - 174
Journal Article
by Ahn, JH and Woo, JH and Rho, JR and Choi, JH
MARINE DRUGS, ISSN 1660-3397, 02/2019, Volume 17, Issue 2, p. 126
Gukulenin A is a bis-tropolone tetraterpenoid isolated from the marine sponge Phorbas gukhulensis. In this study, we examined the anticancer activities of... 
CELLS | CHEMISTRY, MEDICINAL | EFFICACY | E7389 | ovarian cancer | apoptosis | OVARIAN-CANCER | Phorbas gukhulensis | tumor xenograft model | gukulenin A | DISCODERMOLIDE | TAXOL | TRABECTEDIN
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2016, Volume 138, Issue 50, pp. 16248 - 16251
Recently reported Pd-mediated one-pot ketone synthesis from an unactivated alkyl bromide and a thioester has been extended to a macrocyclic ketone synthesis.... 
HALICHONDRIN-B | ROUTE | E7389 | CHEMISTRY, MULTIDISCIPLINARY | MACROLIDE | MARINE SPONGE | Palladium catalysts | Usage | Analysis | Methyl groups | Chemical bonds | Chemical properties | Chemical synthesis | Electron transport
Journal Article
Journal Article
British Journal of Cancer, ISSN 0007-0920, 02/2019, Volume 120, Issue 4, pp. 379 - 386
BACKGROUND: This phase 1 study examined the safety, tolerability, pharmacokinetics and preliminary efficacy of eribulinliposomal formulation (eribulin-LF) in... 
MECHANISM | ONCOLOGY | MESYLATE E7389 | METASTATIC BREAST-CANCER | Schedules | Alanine | Toxicity | Transaminase | Radioactive half-life | Pharmacology | Patients | Stomatitis | Safety engineering | Alanine transaminase | Hypophosphatemia | Solid tumors | Pharmacokinetics | Tumors | Neutropenia | Index Medicus | Breast cancer
Journal Article
Lung Cancer, ISSN 0169-5002, 04/2018, Volume 118, pp. 148 - 154
Small cell lung cancer (SCLC) patients of all stages are treated with etoposide and cisplatin or carboplatin with or without surgery or chest radiotherapy.... 
SCLC | Eribulin | Non-taxane microtubule inhibitor | THERAPEUTICS | TRIAL | HALICHONDRIN-B | E7389 | ANALOG | ONCOLOGY | RESPIRATORY SYSTEM | METASTATIC BREAST-CANCER | Index Medicus
Journal Article
Synthesis, ISSN 0039-7881, 06/2016, Volume 48, Issue 11, pp. 1663 - 1683
Abstract A practical and scalable stereoselective synthesis of the western substituted tetrahydrofuran ring C27–C35 fragment of eribulin was developed by using... 
special topic | natural products | halichondrins | macrocycles | medicinal chemistry | eribulin | stereoselective synthesis | TOOLBOX | E7389 | HALAVEN | CHEMISTRY, ORGANIC | HALICHONDRIN B | TUBULIN
Journal Article