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Journal of Neuroscience, ISSN 0270-6474, 08/2007, Volume 27, Issue 35, pp. 9525 - 9533
Oligodendrocyte death and demyelination are hallmarks of multiple sclerosis (MS). Here we show that ATP signaling can trigger oligodendrocyte excitotoxicity... 
EAE | Multiple sclerosis | Demyelination | ATP | Excitotoxicity | Oligodendrocytes | oligodendrocytes | excitotoxicity | demyelination | multiple sclerosis
Journal Article
Brain, behavior, and immunity, ISSN 0889-1591, 06/2019
Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that promotes immune modulation and tissue regeneration and is recognized as a potential... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2019, Volume 116, Issue 3, pp. 982 - 987
Journal Article
Brain Research Bulletin, ISSN 0361-9230, 11/2019, Volume 153, pp. 30 - 38
Stressed oligodendrocytes (OLGs) activate microglia to produce an inflammatory response, and the impairment of mitochondria further aggravates OLG damage,... 
EAE | MAT | Mitochondria | OLG | Autophagy | Index Medicus
Journal Article
Multiple Sclerosis Journal, ISSN 1352-4585, 2019, pp. 1352458518822408 - 1352458518822408
Experimental autoimmune encephalomyelitis (EAE) in the common marmoset is a nonhuman primate model of multiple sclerosis (MS) that shares numerous clinical,... 
EAE | Multiple sclerosis | marmoset | spinal cord | MRI
Journal Article
The Journal of Chemical Thermodynamics, ISSN 0021-9614, 12/2019, Volume 139, p. 105862
The absorption amount ( ) and loading ( ) of CO in 2-(ethylamino)ethanol (EAE) activated 3-(dimethylamino)propan-1-ol (3DMA1P) aqueous solution were measured.... 
EAE | Absorption performance | Removal efficiency | 3DMA1P | CO2
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 01/2016, Volume 20, Issue 1, pp. 81 - 94
Myelin oligodendrocyte glycoprotein ( MOG ) is an antigen of the myelin sheath, which may trigger immune cell responses and the production of auto‐antibodies... 
6 mice | hematopoietic progenitors | catalytic antibodies | EAE | apoptosis in different organs | colony formation | BL | model, C57 | lymphocyte proliferation | Lymphocyte proliferation | Hematopoietic progenitors | Catalytic antibodies | Colony formation | Apoptosis in different organs | EAE model, C57BL/6 mice | AUTOANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | SERA | EAE model | CELL BIOLOGY | B-CELLS | HETEROGENEITY | HYDROLYZING ANTIBODIES | MULTIPLE-SCLEROSIS | C57BL/6 mice | AUTOIMMUNE-DISEASES | DNA | BASIC-PROTEIN | Myelin-Oligodendrocyte Glycoprotein - immunology | Cell Proliferation | Encephalomyelitis, Autoimmune, Experimental - pathology | Lymphocyte Activation | Mice, Inbred C57BL | Cells, Cultured | Encephalomyelitis, Autoimmune, Experimental - immunology | Lymphocytes - physiology | Animals | Hematopoietic Stem Cells - physiology | Mice, Inbred CBA | Mice, Inbred BALB C | Apoptosis | Lymphocytes | Analysis | Hematopoietic stem cells | Myelin proteins | Bone marrow | Multiple sclerosis | Immunoglobulins | Glycoproteins | Immune system | Cell proliferation | Oligodendrocyte-myelin glycoprotein | Abzymes | Encephalomyelitis | Pathogenesis | Immunoglobulin G | Antibodies | Stem cell transplantation | Myelin basic protein | Thymus | Sheaths | Proteolysis | Deoxyribonucleic acid--DNA | Lupus | Spleen | Antigens | Deoxyribonuclease | Immunization | Statistical analysis | Myelin | Glycoprotein | Organs | Chemical reactions | Experimental allergic encephalomyelitis | Hemopoiesis | Immune systems | Stem cells | Mice | Autoimmune diseases | Proteinuria | Index Medicus | EAE model, C57BL | Original
Journal Article
Neuroscience, ISSN 0306-4522, 09/2019, Volume 416, pp. 74 - 87
Multiple sclerosis (MS) is a demyelination disease that causes gradual damage to neurons. Despite the necessity of appropriate treatments at each disease stage... 
EAE | metabolomics | neuroinflammation | multiple sclerosis | lipidomics | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2908, 7/2016, Volume 17, Issue 7, pp. 797 - 805
Perivascular, meningeal and choroid plexus macrophages are non-parenchymal macrophages that mediate immune responses at brain boundaries. Although the origin... 
CX3CR1 | EAE | inflammation | multiple sclerosis
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2011, Volume 163, Issue 7, pp. 1507 - 1519
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 53, Issue C, pp. 95 - 104
Unlike genetic alterations, epigenetic modifications are reversible and amenable to pharmacological interventions, which make them appealing targets for... 
EAE | Epigenetic | Methylation | T-bet | MBD2
Journal Article
National Medical Journal of China, ISSN 0376-2491, 06/2018, Volume 98, Issue 23, pp. 1873 - 1875
Journal Article
Molecular Immunology, ISSN 0161-5890, 10/2013, Volume 55, Issue 3-4, pp. 237 - 246
► Intraperitoneal administration of rCRT/39-272 inhibits murine EAE. ► rCRT/39-272 activates and expands mouse splenic B10 cells in vitro. ► rCRT/39-272... 
EAE | RegulatoryB cells | Calreticulin | IL-10
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2017, Volume 37, Issue 38, pp. 9332 - 9344
Journal Article
Nature immunology, ISSN 1529-2908, 3/2016, Volume 17, Issue 3, pp. 259 - 268
The proinflammatory cytokines interleukin 12 (IL-12) and IL-23 connect innate and adaptive immune responses and are also involved in autoimmune and... 
EAE | Trabid | Ubiquitination | IL-12 | Jmjd2d
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 2/2016, Volume 196, Issue 4, pp. 1455 - 1459
Myeloid cells play a crucial role in the induction and sustained inflammation in neuroinflammatory disorders such as MS. miR-223, a myeloid cell-specific... 
miR-223 | EAE | Ag presentation | mDCs | TH17
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 12/2017, Volume 23, Issue 12, pp. 2093 - 2095
Journal Article
European Journal of Immunology, ISSN 0014-2980, 10/2014, Volume 44, Issue 10, pp. 2903 - 2917
Journal Article
Clinical Immunology, ISSN 1521-6616, 09/2016, Volume 170, pp. 22 - 30
Interleukin 17 (IL-17), produced by T cells, plays an important role in Multiple Sclerosis (MS) and its animal model, Experimental Autoimmune Encephalomyelitis... 
MOG | T cell | IL-17 | EAE | TLR
Journal Article
Glia, ISSN 0894-1491, 11/2016, Volume 64, Issue 11, pp. 1925 - 1937
Intracerebral levels of Transforming Growth Factor beta (TGFβ) rise rapidly during the onset of experimental autoimmune encephalomyelitis (EAE), a mouse model... 
TGFβ | monocyte‐derived dendritic cells | MOG‐EAE | reactive oxygen species | gene deletion | Reactive oxygen species | Gene deletion | Monocyte-derived dendritic cells | MOG-EAE | monocyte-derived dendritic cells | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MACROPHAGES | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | NEUROSCIENCES | EFFECTOR PHASE | MULTIPLE-SCLEROSIS | ADOPTIVE TRANSFER | MICROGLIA | C-MET | TGF beta | T-CELLS | CYTOKINE GM-CSF | Myelin-Oligodendrocyte Glycoprotein - immunology | Th1 Cells - physiology | Leukocyte Common Antigens - metabolism | Reactive Oxygen Species - metabolism | Monocytes - cytology | Humans | Dendritic Cells - physiology | Encephalomyelitis, Autoimmune, Experimental - immunology | Myelin-Oligodendrocyte Glycoprotein - toxicity | Encephalomyelitis, Autoimmune, Experimental - genetics | Cytokines - genetics | Disease Models, Animal | Encephalomyelitis, Autoimmune, Experimental - pathology | Cytokines - metabolism | Gene Expression Regulation - genetics | Amyotrophic Lateral Sclerosis - genetics | Mice, Inbred C57BL | Genotype | Mice, Transgenic | Cell Polarity - genetics | Amyotrophic Lateral Sclerosis - pathology | Animals | Transforming Growth Factor beta - genetics | NADPH Oxidase 2 - metabolism | Polymorphism, Single Nucleotide - genetics | Cell Polarity - physiology | Leukocyte Common Antigens - genetics | Mice | NADPH Oxidase 2 - genetics | Transforming Growth Factor beta - metabolism | Cohort Studies | Index Medicus | s
Journal Article
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