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The Journal of neuroscience, ISSN 1529-2401, 2007, Volume 27, Issue 35, pp. 9525 - 9533
Oligodendrocyte death and demyelination are hallmarks of multiple sclerosis (MS). Here we show that ATP signaling can trigger oligodendrocyte excitotoxicity... 
EAE | Multiple sclerosis | Demyelination | ATP | Excitotoxicity | Oligodendrocytes | oligodendrocytes | excitotoxicity | demyelination | multiple sclerosis
Journal Article
Journal Article
Nature immunology, ISSN 1529-2908, 7/2016, Volume 17, Issue 7, pp. 797 - 805
Perivascular, meningeal and choroid plexus macrophages are non-parenchymal macrophages that mediate immune responses at brain boundaries. Although the origin... 
CX3CR1 | EAE | inflammation | multiple sclerosis
Journal Article
Glia, ISSN 0894-1491, 11/2016, Volume 64, Issue 11, pp. 1925 - 1937
Intracerebral levels of Transforming Growth Factor beta (TGFβ) rise rapidly during the onset of experimental autoimmune encephalomyelitis (EAE), a mouse model... 
TGF beta | MOG-EAE | monocyte-derived dendritic cells | reactive oxygen species | gene deletion | TGFβ | monocyte‐derived dendritic cells | MOG‐EAE | Reactive oxygen species | Gene deletion | Monocyte-derived dendritic cells | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MACROPHAGES | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | NEUROSCIENCES | EFFECTOR PHASE | MULTIPLE-SCLEROSIS | ADOPTIVE TRANSFER | MICROGLIA | C-MET | T-CELLS | CYTOKINE GM-CSF | Myelin-Oligodendrocyte Glycoprotein - immunology | Th1 Cells - physiology | Leukocyte Common Antigens - metabolism | Reactive Oxygen Species - metabolism | Monocytes - cytology | Humans | Dendritic Cells - physiology | Encephalomyelitis, Autoimmune, Experimental - immunology | Myelin-Oligodendrocyte Glycoprotein - toxicity | Encephalomyelitis, Autoimmune, Experimental - genetics | Cytokines - genetics | Disease Models, Animal | Encephalomyelitis, Autoimmune, Experimental - pathology | Cytokines - metabolism | Gene Expression Regulation - genetics | Amyotrophic Lateral Sclerosis - genetics | Mice, Inbred C57BL | Genotype | Mice, Transgenic | Cell Polarity - genetics | Amyotrophic Lateral Sclerosis - pathology | Animals | Transforming Growth Factor beta - genetics | NADPH Oxidase 2 - metabolism | Polymorphism, Single Nucleotide - genetics | Cell Polarity - physiology | Leukocyte Common Antigens - genetics | Mice | NADPH Oxidase 2 - genetics | Transforming Growth Factor beta - metabolism | Cohort Studies
Journal Article
Nature immunology, ISSN 1529-2908, 3/2016, Volume 17, Issue 3, pp. 259 - 268
The proinflammatory cytokines interleukin 12 (IL-12) and IL-23 connect innate and adaptive immune responses and are also involved in autoimmune and... 
EAE | Trabid | Ubiquitination | IL-12 | Jmjd2d
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 2/2016, Volume 196, Issue 4, pp. 1455 - 1459
Myeloid cells play a crucial role in the induction and sustained inflammation in neuroinflammatory disorders such as MS. miR-223, a myeloid cell-specific... 
miR-223 | EAE | Ag presentation | mDCs | TH17
Journal Article
Journal Article
Journal of neuroimmunology, ISSN 0165-5728, 2015, Volume 278, pp. 112 - 122
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 5/2015, Volume 194, Issue 9, pp. 4251 - 4264
IFN-γ, the hallmark cytokine of Th1 cells, plays an important role in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis... 
EAE | IFN-γ | astrocytes | microglia
Journal Article
Journal Article
Journal of cellular and molecular medicine, ISSN 1582-1838, 01/2016, Volume 20, Issue 1, pp. 81 - 94
Myelin oligodendrocyte glycoprotein (MOG) is an antigen of the myelin sheath, which may trigger immune cell responses and the production of auto‐antibodies in... 
apoptosis in different organs | colony formation | hematopoietic progenitors | catalytic antibodies | lymphocyte proliferation | EAE model, C57BL/6 mice | Lymphocyte proliferation | Hematopoietic progenitors | Catalytic antibodies | Colony formation | Apoptosis in different organs | AUTOANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | SERA | EAE model | CELL BIOLOGY | B-CELLS | HETEROGENEITY | HYDROLYZING ANTIBODIES | MULTIPLE-SCLEROSIS | C57BL/6 mice | AUTOIMMUNE-DISEASES | DNA | BASIC-PROTEIN | Myelin-Oligodendrocyte Glycoprotein - immunology | Cell Proliferation | Encephalomyelitis, Autoimmune, Experimental - pathology | Lymphocyte Activation | Mice, Inbred C57BL | Cells, Cultured | Encephalomyelitis, Autoimmune, Experimental - immunology | Lymphocytes - physiology | Animals | Hematopoietic Stem Cells - physiology | Mice, Inbred CBA | Mice, Inbred BALB C | Apoptosis | Lymphocytes | Analysis | Hematopoietic stem cells | Myelin proteins | Bone marrow | Multiple sclerosis | Immunoglobulins | Glycoproteins | Immune system | Cell proliferation | Oligodendrocyte-myelin glycoprotein | Abzymes | Pathogenesis | Immunoglobulin G | Antibodies | Stem cell transplantation | Myelin basic protein | Thymus | Sheaths | Proteolysis | Deoxyribonucleic acid--DNA | Lupus | Spleen | Antigens | Deoxyribonuclease | Immunization | Statistical analysis | Myelin | Organs | Chemical reactions | Experimental allergic encephalomyelitis | Hemopoiesis | Stem cells | Mice | Autoimmune diseases | Proteinuria | 6 mice | EAE model, C57BL | Original
Journal Article
Frontiers in neurology, ISSN 1664-2295, 2012, Volume 3, p. 84
Resveratrol is a naturally occurring polyphenol that activates SIRT1, an NAD-dependent deacetylase. SRT501, a pharmaceutical formulation of resveratrol with... 
EAE | Neuroprotection | Multiple sclerosis | SIRT1 | Optic neuritis | Resveratrol | Multiple Sclerosis | Optic Neuritis | resveratrol
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2016, Volume 7
Most multiple sclerosis (MS) patients develop over time a secondary progressive disease course, characterized histologically by axonal loss and atrophy. In... 
FLIM-FRET | Intravital imaging | Calcium | NOX | EAE/MS | calcium | MONOCYTES | INJURY | CNS | MODEL | IMMUNOLOGY | LESIONS | DAMAGE | MULTIPLE-SCLEROSIS | DEMYELINATION | MICROGLIA | INFLAMMATION | intravital imaging
Journal Article
International immunopharmacology, ISSN 1567-5769, 2011, Volume 11, Issue 7, pp. 789 - 793
Journal Article