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Oncotarget, ISSN 1949-2553, 06/2018, Volume 9, Issue 47, pp. 28652 - 28665
Meningioma is a primary brain tumor arising from the neoplastic transformation of meningothelial cells. Several histological variants of meningioma have been... 
Epithelial differentiation | NF2 | NHERF1/EBP50 | Chordoid meningioma | Microvilli
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2019, Volume 379, p. 114638
Our previous study has demonstrated that 4-amino-2-trifluoromethyl-phenyl Retinate (ATPR) can induce human leukemia NB4 cells differentiation and G0/G1 phase... 
Acute promyelocytic leukemia (APL) | G0/G1 cell cycle arrest | NCF1 | Differentiation | 4-amino-2-trifluoromethyl-phenyl retinate (ATPR) | EBP50 | MIGRATION | APOPTOSIS | CELL-CYCLE ARREST | COMBINATION | VITAMIN-K-2 | THERAPY | 4-AMINO-2-TRIFLUOROMETHYL-PHENYL RETINATE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | UP-REGULATION | NHERF1/EBP50 | EXPRESSION
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2010, Volume 49, Issue 6, pp. 1012 - 1021
Journal Article
by Wang, L and Du, YR and Ji, MY and Wang, W and Zhan, N and Zhou, QS and Dong, WG
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 12/2014, Volume 18, Issue 24, pp. 3854 - 3863
PURPOSE: The aim of this study was to examine the significance of EBP50 (ezrin-radixin-moesin binding phosphoprotein 50) expression in esophageal squamous cell... 
Prognosis | EZRIN | EPITHELIA | EBP50 | Malignant Progression | PHARMACOLOGY & PHARMACY | NHERF1/EBP50 | ESCC | Prognostic marker | MOESIN-BINDING PHOSPHOPROTEIN-50
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2012, Volume 32, Issue 1, pp. 33 - 41
OBJECTIVE—The Ezrin-radixin–moesin–binding phosphoprotein 50 (EBP50) is a scaffolding protein known to regulate ion homeostasis in the kidney and intestine.... 
smooth muscle | NHERF1 | p21cip1 | proliferation | EBP50 | Skp2
Journal Article
ACTA HISTOCHEMICA, ISSN 0065-1281, 2016, Volume 118, Issue 8, pp. 797 - 805
NHERFI is an adaptor protein expressed in the apical membrane of polarized epithelia, which interacts with the EZRIN-Radixin-Moesin (ERM) family of proteins... 
SURFACE EPITHELIUM | ERM PROTEINS | BREAST CARCINOMAS | TUMORS | Ovarian cancer | CELL BIOLOGY | EZRIN | COLORECTAL-CANCER | EBP50 EXPRESSION | Papillary differentiation | PREDICTS POOR-PROGNOSIS | NHERFI | Apical localization | CELL | NHERF1/EBP50 | BINDING
Journal Article
Journal of cell science, ISSN 0021-9533, 10/2018, Volume 131, Issue 20, p. jcs221853
Cells of transporting epithelia are characterized by the presence of abundant F-actin-based microvilli on their apical surfaces. Likewise, auditory hair cells... 
Stereocilia | Cytoskeleton | Cell polarity | Actin | ERM proteins | Microvilli | F-ACTIN | THREONINE 558 | TIP-LINK | PROTRACTED DIARRHEA | CELL BIOLOGY | HAIR-CELLS | TERMINAL REGION | CYSTIC-FIBROSIS | BETA-ADRENERGIC RECEPTOR | PLANAR POLARITY | SCAFFOLDING PROTEIN EBP50 | 136 | Review
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 08/2019, Volume 33, Issue 8, pp. 9008 - 9016
Na+/H+ exchanger regulatory factor 1 (NHERF1; also known as ezrin-radixin-moesin-binding phosphoprotein 50) is a PSD-95, disc large, zona occludens-1 adapter... 
PROTEIN-KINASE-A | ADAPTER PROTEINS | EBP50 | COMPARTMENTALIZED CAMP | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PKA | asthma | c/EBP | BETA | CELL BIOLOGY | compartmentalized signaling | ADENYLYL-CYCLASE | BIOLOGY | BINDING | BETA-ADRENERGIC RECEPTOR
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2016, Volume 113, Issue 36, pp. E5308 - E5317
Despite numerous reports implicating NADPH oxidases (Nox) in the pathogenesis of many diseases, precise regulation of this family of professional reactive... 
ACTIVATION | NADPH OXIDASE 1 | EBP50 | hypertrophy | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | smooth muscle | ANGIOTENSIN-II | SENSITIVE SIGNALING PATHWAYS | vascular tone | STRUCTURAL BASIS | PDZ DOMAINS | NADPH oxidase | SMOOTH-MUSCLE-CELLS | EXPRESSION
Journal Article
2016
Over the last decade, Scotland has witnessed a rising incidence in squamous cell carcinomas of the head and neck (HNSCC), a phenomenon thought to be linked to... 
EBP50 | HPV
Dissertation
Cancer Biology & Therapy, ISSN 1538-4047, 08/2015, Volume 16, Issue 8, pp. 1140 - 1147
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2019, Volume 294, Issue 3, pp. 887 - 901
Unlike other ErbB family members, HER2 levels are maintained on the cell surface when the receptor is activated, allowing prolonged signaling and contributing... 
heat shock protein 90 (Hsp90) | NHERF1 | protein kinase C (PKC) | scaffold protein | breast cancer | ErbB2/HER2 | ezrin | PDZ domain | PMCA2 | LOCALIZATION | ACTIVATION | COMPLEX | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERACTS | PRODUCT | RECEPTORS | ASSOCIATION | NHERF1/EBP50 | REVEALS
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2015, Volume 89, pp. 34 - 46
The development and progression of liver cancer are characterized by increased levels of reactive oxygen species (ROS). ROS-induced oxidative stress impairs... 
Reactive oxygen species | Hydrogen peroxide | Free radicals | MAPKAPK2 | Hepatocellular carcinoma | EBP50/NHERF-1 | Cholangiocarcinoma | EGFR | EBE50/NHERF-1 | AKT ACTIVATION | PHOSPHORYLATION | ASSOCIATING PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR RECEPTOR | HEAT-SHOCK PROTEINS | HEPATOCELLULAR-CARCINOMA | EPIDERMAL-GROWTH-FACTOR | ENDOCRINOLOGY & METABOLISM | MAPKAP KINASE-2 | PHOSPHOPROTEIN 50 EBP50 | EXPRESSION | Oxidants - pharmacology | Immunoprecipitation | Prognosis | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Middle Aged | Male | Intracellular Signaling Peptides and Proteins - metabolism | Immunoenzyme Techniques | HSP27 Heat-Shock Proteins - genetics | Neoplasm Grading | Biliary Tract Neoplasms - metabolism | Female | Liver Neoplasms - pathology | Biliary Tract Neoplasms - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Tumor Cells, Cultured | Biliary Tract Neoplasms - genetics | Intracellular Signaling Peptides and Proteins - genetics | Real-Time Polymerase Chain Reaction | Protein-Serine-Threonine Kinases - metabolism | Biliary Tract Neoplasms - pathology | Liver Neoplasms - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | Hydrogen Peroxide - pharmacology | Liver Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - genetics | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Two-Hybrid System Techniques | Signal Transduction - drug effects | Liver Neoplasms - metabolism | HSP27 Heat-Shock Proteins - metabolism | Mitogen-Activated Protein Kinases - genetics | Aged | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Neoplasm Staging | Mitogen-Activated Protein Kinases - metabolism | Oxidative stress | Glycosaminoglycans | Liver | Heat shock proteins | Development and progression | Anticoagulants (Medicine) | Antioxidants | Liver cancer | Cancer cells | Physiological aspects | Mitogens | Protein kinases | Epidermal growth factor | Cell death | Heme | Life Sciences | Human health and pathology | Hépatology and Gastroenterology | Cancer
Journal Article