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index medicus (103) 103
humans (100) 100
clinical neurology (84) 84
male (84) 84
female (83) 83
aged (80) 80
tissue-plasminogen activator (75) 75
middle aged (70) 70
ecass-ii (64) 64
acute ischemic-stroke (57) 57
stroke (55) 55
stroke - drug therapy (55) 55
thrombolytic therapy (53) 53
ecass ii (51) 51
treatment outcome (47) 47
peripheral vascular disease (46) 46
thrombolysis (46) 46
aged, 80 and over (41) 41
alteplase (41) 41
risk factors (40) 40
therapy (37) 37
retrospective studies (33) 33
fibrinolytic agents - adverse effects (31) 31
hemorrhagic transformation (31) 31
tissue plasminogen activator - adverse effects (30) 30
fibrinolytic agents - therapeutic use (28) 28
intracerebral hemorrhage (28) 28
tissue plasminogen activator - therapeutic use (27) 27
intravenous thrombolysis (26) 26
neurosciences (26) 26
thrombolytic therapy - adverse effects (26) 26
tomography, x-ray computed (26) 26
brain ischemia - drug therapy (25) 25
neurology (24) 24
adult (23) 23
cerebral hemorrhage - chemically induced (23) 23
prospective studies (23) 23
time factors (23) 23
controlled-trial (22) 22
cooperative acute stroke (22) 22
predictive value of tests (22) 22
acute ischemic stroke (21) 21
fibrinolytic agents - administration & dosage (21) 21
tissue plasminogen activator (20) 20
tissue plasminogen activator - administration & dosage (20) 20
stroke - diagnostic imaging (19) 19
risk-factors (18) 18
stroke - diagnosis (17) 17
stroke - physiopathology (17) 17
association (16) 16
double-blind (16) 16
hemorrhage (16) 16
thrombolytic therapy - methods (16) 16
acute disease (15) 15
prognosis (15) 15
transformation (15) 15
brain ischemia - complications (14) 14
brain ischemia - diagnostic imaging (14) 14
intracranial hemorrhage (14) 14
severity of illness index (14) 14
stroke - complications (14) 14
stroke - therapy (14) 14
tissue-plasminogen-activator (14) 14
computed-tomography (13) 13
logistic models (13) 13
acute stroke (12) 12
brain ischemia - diagnosis (12) 12
cerebral hemorrhage - epidemiology (12) 12
cerebral hemorrhage - etiology (12) 12
magnetic resonance imaging (12) 12
risk (12) 12
stroke - etiology (12) 12
trial (12) 12
abridged index medicus (11) 11
analysis (11) 11
atlantis (11) 11
cerebral hemorrhage - diagnostic imaging (11) 11
infusions, intravenous (11) 11
stroke - mortality (11) 11
tomography, x-ray computed - methods (11) 11
brain ischemia - physiopathology (10) 10
intravenous alteplase (10) 10
ischemic stroke (10) 10
management (10) 10
odds ratio (10) 10
risk assessment (10) 10
ischemia (9) 9
outcomes (9) 9
registries (9) 9
stroke - epidemiology (9) 9
symptomatic intracerebral hemorrhage (9) 9
care and treatment (8) 8
cerebral hemorrhage - diagnosis (8) 8
cerebral infarction (8) 8
intraarterial thrombolysis (8) 8
mortality (8) 8
multivariate analysis (8) 8
original paper (8) 8
randomized controlled-trial (8) 8
recanalization (8) 8
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LANCET, ISSN 0140-6736, 10/2008, Volume 372, Issue 9646, pp. 1303 - 1309
Background Intravenous alteplase is approved for use within 3 h of ischaemic stroke onset, although a meta-analysis of randomised controlled trials suggests... 
CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | MULTICENTER | THERAPY | MANAGEMENT | TISSUE-PLASMINOGEN ACTIVATOR | GUIDELINES | DOUBLE-BLIND | ECASS II | ATLANTIS | ASSOCIATION
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2008, Volume 359, Issue 13, pp. 1317 - 1329
Journal Article
Lancet, The, ISSN 0140-6736, 2007, Volume 369, Issue 9558, pp. 275 - 282
Journal Article
Circulation, ISSN 0009-7322, 04/2002, Volume 105, Issue 14, pp. 1679 - 1685
Background-Intravenous recombinant tissue plasminogen activator (rtPA) is an effective therapy for acute ischemic stroke, but it is associated with risk of... 
Hemorrhage | Plasminogen activators | Stroke | TRANSFORMATION | CARDIAC & CARDIOVASCULAR SYSTEMS | ALTEPLASE | PERIPHERAL VASCULAR DISEASE | EXPERIENCE | plasminogen activators | SCALE | HEMATOLOGY | stroke | THROMBOLYTIC THERAPY | hemorrhage | ECASS-II
Journal Article
DIABETES CARE, ISSN 0149-5992, 12/2010, Volume 33, Issue 12, pp. 2531 - 2537
OBJECTIVE - The use of alteplase in patients who have had a prior stroke and concomitant diabetes is not approved in Europe To examine the influence of... 
INTRAVENOUS ALTEPLASE | HYPERGLYCEMIA | PLASMINOGEN-ACTIVATOR | DICHOTOMIZATION | ACUTE ISCHEMIC-STROKE | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | ATLANTIS | SCALES | CEREBRAL-ISCHEMIA | ECASS-II
Journal Article
Journal Article
Journal Article
Journal Article
Journal of NeuroInterventional Surgery, ISSN 1759-8478, 01/2018, Volume 10, Issue 1, pp. 17 - 21
Background Limited efficacy of IV recombinant tissue plasminogen activator (rt-PA) for large vessel occlusions (LVO) raises doubts about its utility prior to... 
Economics | Intervention | SURGERY | PREDICTS | Stroke | TISSUE-PLASMINOGEN ACTIVATOR | IV-TPA | ECASS II | TRANSCRANIAL DOPPLER | MODEL | NEUROIMAGING | Thrombectomy | ACUTE ISCHEMIC-STROKE | ELEVATION MYOCARDIAL-INFARCTION | Studies | Heart attacks | Financial analysis | Patients | Clinical outcomes | Index Medicus | 1546 | Ischemic Stroke | 1506
Journal Article
Journal Article